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Publication Detail

Title: Deposition of charged particles on lung airways.

Authors: Cohen, B S; Xiong, J Q; Fang, C P; Li, W

Published In Health Phys, (1998 May)

Abstract: The effect of a single electric charge on the efficiency with which ultrafine particles deposit in human airways has been investigated. When inhaled short-lived radon progeny are attached to electrically neutral particles their deposition efficiency is controlled by diffusion. But most ambient particles carry one, or a few, charges. We measured and compared the deposition (DE) of singly charged, charge-neutralized, and zero-charge 20-nm and 125-nm particles in hollow-cast models of human airways. These particle sizes were selected because they are about where modal peaks occur for the activity of the short-lived radon progeny in indoor air. For singly charged 20-nm particles deposition (+/- standard error) in the casts was 3.4 +/- 0.3 times that for charge neutralized aerosols and 5.3 +/- 0.3 times the amount deposited for zero-charged particles. Corresponding ratios for the 125-nm particles were 2.3 +/- 0.3 and 6.2 +/- 0.7. Since most ambient particles are charged this effect must be considered when models are used to predict dose from inhaled ultrafine particles.

PubMed ID: 9570158 Exiting the NIEHS site

MeSH Terms: Adult; Aerosols; Humans; Ions*; Lung/metabolism*; Male; Models, Structural; Plastics; Respiratory System/metabolism*; Surface Properties; Trachea

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