Title: Polonium metabolism in adult female baboons.
Authors: Fellman, A; Ralston, L; Hickman, D; Ayres, L; Cohen, N
Published In Radiat Res, (1994 Feb)
Abstract: The biokinetics of polonium in nonhuman primates (Papio anubis) has been studied after intravenous injection of 210Po citrate. The urinary excretion of polonium in the baboon could be described by a single exponential function with a half-time of 15.6 days. Excretion fractions of polonium were found to be markedly different from those reported for other species, including humans. Polonium-210 was found to be distributed throughout the soft tissues of the baboon with 29% of the injected polonium being deposited in liver, 7% in kidneys and 0.6% in spleen. Retention of polonium in all tissues exhibited single exponential functions; however, the biological half-times were variable, ranging from 15 to 50 days.
PubMed ID: 8134548
MeSH Terms: Animals; Feces/chemistry; Female; Papio; Polonium/pharmacokinetics*; Tissue Distribution