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Publication Detail

Title: Peak flow rate changes in O3 exposed children: spirometry vs miniWright flow meters.

Authors: Lippmann, M; Spektor, D M

Published In J Expo Anal Environ Epidemiol, (1998 Jan-Mar)

Abstract: We compared "miniWright" peak flow (mWPF) readings with spirometric peak expiratory flow rates (PEFR) in 91 children, aged 8-15, exposed to ambient air at a summer camp in northwestern New Jersey. mWPF measurements immediately preceded spirometry, and mWPF-PEFR differences were regressed on spirometric PEFR by child. The ratio (mWPF-PEFR)/PEFR (mean +/- SE) was -0.027 +/- 0.028 (n = 91) (NS). When subdivided into PEFR ranges, the ratios were: -0.089 +/- 0.060 (n = 17) for 2-<4 Liters/second (Lps) (p = 0.04), -0.019 +/- 0.038 (n = 50) for 4-<6 Lps (NS); and -0.000 +/- 0.044 (n = 24) for 6-<8 Lps (NS). The mWPF values were also regressed on the average ozone (O3) concentration in the previous hour, by child. The mWPF response for O3 was -6.63 +/- 0.76 mL/sec/ppb, compared to -6.78 +/- 0.73 mL/sec/ppb O3 for PEFR. Thus: 1) mWPF, with an overall underestimation of approximately 2%, is a useful surrogate for spirometric values of PEFR (although, for the smallest children studied, it underestimated peak flows by approximately 9%), and 2) the portable miniWright peak flow meter is a convenient and effective tool for characterizing changes in PEFR associated with exposures to ambient O3.

PubMed ID: 9470108 Exiting the NIEHS site

MeSH Terms: Adolescent; Air Pollution/analysis*; Calibration; Child; Environmental Exposure*; Female; Humans; Male; Ozone*; Peak Expiratory Flow Rate*; Reproducibility of Results; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Spirometry

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