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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Dihalomethyl compounds as mechanism-based inactivators of cytochromes P450.

Authors: Halpert, J R; Stevens, J C

Published In Methods Enzymol, (1991)

Abstract: Abstract not available from PubMed.

PubMed ID: 1784240 Exiting the NIEHS site

MeSH Terms: Acetamides/pharmacology*; Animals; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors*; Drug Design; Enzyme Inhibitors/pharmacology*; Hydrocarbons, Halogenated/pharmacology*; Isoenzymes/antagonists & inhibitors*; Kinetics; Microsomes, Liver/enzymology; Radioisotope Dilution Technique; Rats

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