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Who We Fund: Publications associated with Basic Cellular And Molecular Research - Genome Integrity

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 748 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
A precision medicine approach to defining the impact of doxorubicin on the bioenergetic-metabolite i ...   Smith, Matthew Ryan; Chacko, Balu K; Johnson, Michelle S; Benavides, Gloria A; Uppal, Karan; Go ... P30ES019776, R01ES023485, U2CES026560 Redox Biol (2020 01) 31546171 Exiting the NIEHS site 2020 
A special issue dedicated to Dr. Bruce N. Ames: Introduction.   Walker, Graham C R35ES028303 Mutat Res (2020 01) 32087846 Exiting the NIEHS site 2020 
A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis.   Chatterjee, Nimrat; D'Souza, Sanjay; Shabab, Mohammad; Harris, Cynthia A; Hilinski, Gerard J; V ... P30ES002109, R35ES028303 Environ Mol Mutagen (2020 Jun 23) 32573829 Exiting the NIEHS site 2020 
A vision for exposome epidemiology: The pregnancy exposome in relation to breast cancer in the Child ...   Jones, Dean P; Cohn, Barbara A R01ES023485, U2CES026560, U2CES030163 Reprod Toxicol (2020 Mar) 32197999 Exiting the NIEHS site 2020 
Analysis of Telomere Length and Aberrations by Quantitative FISH.   Fouquerel, Elise; Opresko, Patricia R00ES027028 Methods Mol Biol (2020) 31989559 Exiting the NIEHS site 2020 
AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.   Hoitsma, Nicole M; Whitaker, Amy M; Beckwitt, Emily C; Jang, Sunbok; Agarwal, Pratul K; Van Hou ... R01ES029203 Nucleic Acids Res (2020 Jul 27) 32542366 Exiting the NIEHS site 2020 
Arsenic Exposure and Compromised Protein Quality Control.   Tam, Lok Ming; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2020 Jul 20) 32410444 Exiting the NIEHS site 2020 
Arsenite Binds to ZNF598 to Perturb Ribosome-Associated Protein Quality Control.   Tam, Lok Ming; Jiang, Ji; Wang, Pengcheng; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2020 Jul 20) 32324387 Exiting the NIEHS site 2020 
Asymmetric repair of UV damage in nucleosomes imposes a DNA strand polarity on somatic mutations in ...   Mao, Peng; Smerdon, Michael J; Roberts, Steven A; Wyrick, John J R01ES028698 Genome Res (2020 01) 31871068 Exiting the NIEHS site 2020 
Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Famil ...   Yang, Xin; Leslie, Goska; Doroszuk, Alicja; Schneider, Sandra; Allen, Jamie; Decker, Brennan; ... R01ES027121 J Clin Oncol (2020 Mar 01) 31841383 Exiting the NIEHS site 2020 
Collision-Induced Dissociation Studies of Protonated Ions of Alkylated Thymidine and 2'-Deoxyguanosi ...   Cui, Yuxiang; Yuan, Jun; Wang, Pengcheng; Wu, Jun; Yu, Yang; Wang, Yinsheng R01ES029749 J Am Soc Mass Spectrom (2020 Apr 01) 32134268 Exiting the NIEHS site 2020 
Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,N6-Ethenoadenin ...   Caffrey, Paul J; Kher, Raadhika; Bian, Ke; Li, Deyu; Delaney, Sarah R01ES028865, R01ES028865 Chem Res Toxicol (2020 Jul 20) 32293880 Exiting the NIEHS site 2020 
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal M ...   Msaouel, Pavlos; Malouf, Gabriel G; Su, Xiaoping; Yao, Hui; Tripathi, Durga N; Soeung, Melinda ... R01ES029680 Cancer Cell (2020 May 11) 32359397 Exiting the NIEHS site 2020 
Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to ...   Kumar, Namrata; Moreno, Natália C; Feltes, Bruno C; Menck, Carlos Fm; Houten, Bennett Van R01ES019566, R33ES025606 Genet Mol Biol (2020) 32141475 Exiting the NIEHS site 2020 
Defective postreplication repair of UV photoproducts in melanoma: a mutator phenotype.   Brash, Douglas E; Seidman, Michael M R01ES030562 Mol Oncol (2020 01) 31821728 Exiting the NIEHS site 2020 
Development of a DNA Adductome Mass Spectral Database.   Guo, Jingshu; Turesky, Robert J; Tarifa, Anamary; DeCaprio, Anthony P; Cooke, Marcus S; Walmsle ... R01ES019564, R03ES031188 Chem Res Toxicol (2020 Apr 20) 32223224 Exiting the NIEHS site 2020 
DNA polymerase δ proofreads errors made by DNA polymerase ε.   Bulock, Chelsea R; Xing, Xuanxuan; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2020 03 17) 32123096 Exiting the NIEHS site 2020 
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity.   Wilk, Anna; Hayat, Faisal; Cunningham, Richard; Li, Jianfeng; Garavaglia, Silvia; Zamani, Leil ... R01ES014811, U01ES029518, U01ES029518 Sci Rep (2020 01 20) 31959836 Exiting the NIEHS site 2020 
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excisio ...   Koyen, Allyson E; Madden, Matthew Z; Park, Dongkyoo; Minten, Elizabeth V; Kapoor-Vazirani, Priy ... U01ES029520 Oncogene (2020 Jun) 32457468 Exiting the NIEHS site 2020 
Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.   McNeill, Daniel R; Whitaker, Amy M; Stark, Wesley J; Illuzzi, Jennifer L; McKinnon, Peter J; Fr ... R01ES029203 Mutagenesis (2020 02 13) 31816044 Exiting the NIEHS site 2020 
Genome-wide single-nucleotide resolution of oxaliplatin-DNA adduct repair in drug-sensitive and -res ...   Vaughn, Courtney M; Selby, Christopher P; Yang, Yanyan; Hsu, David S; Sancar, Aziz R01ES027255 J Biol Chem (2020 May 29) 32299912 Exiting the NIEHS site 2020 
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanis ...   Bai, Gongshi; Kermi, Chames; Stoy, Henriette; Schiltz, Carl J; Bacal, Julien; Zaino, Angela M; ... R01ES016486 Mol Cell (2020 Jun 18) 32442397 Exiting the NIEHS site 2020 
HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC ...   Mehta, Kavi P M; Lovejoy, Courtney A; Zhao, Runxiang; Heintzman, Darren R; Cortez, David R01ES030575 Cell Rep (2020 Jun 02) 32492421 Exiting the NIEHS site 2020 
Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cance ...   Tsutakawa, Susan E; Sarker, Altaf H; Ng, Clifford; Arvai, Andrew S; Shin, David S; Shih, Brian ... R56ES013773 Proc Natl Acad Sci U S A (2020 Jun 23) 32522879 Exiting the NIEHS site 2020 
Impact of hypoxia on DNA repair and genome integrity.   Kaplan, Alanna R; Glazer, Peter M R01ES005775 Mutagenesis (2020 02 13) 31282537 Exiting the NIEHS site 2020 
Inhibition of base excision repair by natamycin suppresses prostate cancer cell proliferation.   Vasquez, Judy L; Lai, Yanhao; Annamalai, Thirunavukkarasu; Jiang, Zhongliang; Zhang, Manqi; Lei ... R01ES023569 Biochimie (2020 Jan) 31756402 Exiting the NIEHS site 2020 
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA ...   Huang, Jen-Wei; Acharya, Ananya; Taglialatela, Angelo; Nambiar, Tarun S; Cuella-Martin, Raquel; ... R01ES030335 Nat Commun (2020 06 11) 32528060 Exiting the NIEHS site 2020 
Methodologies for detecting environmentally induced DNA damage and repair.   Li, Wentao; Sancar, Aziz K99ES030015, R01ES027255 Environ Mol Mutagen (2020 Feb 21) 32083352 Exiting the NIEHS site 2020 
Mitochondrial dysfunction and DNA damage accompany enhanced levels of formaldehyde in cultured prima ...   Nadalutti, Cristina A; Stefanick, Donna F; Zhao, Ming-Lang; Horton, Julie K; Prasad, Rajendra; ... R56ES013773 Sci Rep (2020 Mar 27) 32221313 Exiting the NIEHS site 2020 
Molecular and structural characterization of disease-associated APE1 polymorphisms.   Whitaker, Amy M; Stark, Wesley J; Flynn, Tony S; Freudenthal, Bret D R01ES029203 DNA Repair (Amst) (2020 Jul - Aug) 32454397 Exiting the NIEHS site 2020 
Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair.   Tam, Lok Ming; Price, Nathan E; Wang, Yinsheng R01ES029749, T32ES018827 Chem Res Toxicol (2020 Mar 16) 31986875 Exiting the NIEHS site 2020 
MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium.   Go, Young-Mi; Zhang, Jing; Fernandes, Jolyn; Litwin, Christopher; Chen, Rui; Wensel, Theodore ... R01ES023485 FASEB J (2020 Jul 28) 32721041 Exiting the NIEHS site 2020 
Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine.   Koag, Myong-Chul; Jung, Hunmin; Lee, Seongmin R01ES026676 Nucleic Acids Res (2020 May 21) 32282906 Exiting the NIEHS site 2020 
N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 ac ...   Zhao, Tianhe; Sun, Donglei; Zhao, Manyu; Lai, Yanhao; Liu, Yuan; Zhang, Zunzhen R01ES023569 Environ Pollut (2020 Apr) 31931413 Exiting the NIEHS site 2020 
New insights into abasic site repair and tolerance.   Thompson, Petria S; Cortez, David R01ES030575 DNA Repair (Amst) (2020 Jun) 32417669 Exiting the NIEHS site 2020 
Oncometabolites suppress DNA repair by disrupting local chromatin signalling.   Sulkowski, Parker L; Oeck, Sebastian; Dow, Jonathan; Economos, Nicholas G; Mirfakhraie, Lily; L ... R01ES005775 Nature (2020 Jun) 32494005 Exiting the NIEHS site 2020 
Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the ...   Jiang, Zhongliang; Lai, Yanhao; Beaver, Jill M; Tsegay, Pawlos S; Zhao, Ming-Lang; Horton, Jul ... R01ES023569 Cells (2020 01 16) 31963223 Exiting the NIEHS site 2020 
Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging.   Vijg, Jan; Dong, Xiao U01ES029519 Cell (2020 Jul 09) 32649873 Exiting the NIEHS site 2020 
Proteome-wide Interrogation of Small GTPases Regulated by N6-Methyladenosine Modulators.   Yang, Yen-Yu; Yu, Kailin; Li, Lin; Huang, Ming; Wang, Yinsheng R35ES031707, T32ES018827 Anal Chem (2020 Jul 21) 32567849 Exiting the NIEHS site 2020 
Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination.   Crickard, J Brooks; Moevus, Corentin J; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Cell (2020 Jun 11) 32502392 Exiting the NIEHS site 2020 
Radiation treatment, ATM, BRCA1/2, and CHEK2*1100delC pathogenic variants, and risk of contralateral ...   Reiner, Anne S; Robson, Mark E; Mellemkjær, Lene; Tischkowitz, Marc; John, Esther M; Lynch, Ch ... R01ES027121 J Natl Cancer Inst (2020 Mar 02) 32119081 Exiting the NIEHS site 2020 
Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1.   Minko, Irina G; Vartanian, Vladimir L; Tozaki, Naoto N; Coskun, Erdem; Coskun, Sanem Hosbas; Ja ... R01ES029357, R01ES031086 DNA Repair (Amst) (2020 01) 31733589 Exiting the NIEHS site 2020 
Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preced ...   Balachander, Sathya; Gombolay, Alli L; Yang, Taehwan; Xu, Penghao; Newnam, Gary; Keskin, Havva ... R01ES026243 Nat Commun (2020 05 15) 32415081 Exiting the NIEHS site 2020 
Single molecule analysis reveals monomeric XPA bends DNA and undergoes episodic linear diffusion dur ...   Beckwitt, Emily C; Jang, Sunbok; Carnaval Detweiler, Isadora; Kuper, Jochen; Sauer, Florian; Si ... R01ES019566 Nat Commun (2020 03 13) 32170071 Exiting the NIEHS site 2020 
Specificity of end resection pathways for double-strand break regions containing ribonucleotides and ...   Daley, James M; Tomimatsu, Nozomi; Hooks, Grace; Wang, Weibin; Miller, Adam S; Xue, Xiaoyu; Ng ... R01ES007061 Nat Commun (2020 Jun 18) 32555206 Exiting the NIEHS site 2020 
The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication.   Tarsounas, Madalena; Sung, Patrick R01ES007061 Nat Rev Mol Cell Biol (2020 05) 32094664 Exiting the NIEHS site 2020 
The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homolo ...   Liang, Fengshan; Miller, Adam S; Tang, Caroline; Maranon, David; Williamson, Elizabeth A; Hroma ... R01ES007061 J Biol Chem (2020 Jun 12) 32350107 Exiting the NIEHS site 2020 
Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules Using a pH-Low Insertion Peptide.   Svoronos, Alexander A; Bahal, Raman; Pereira, Mohan C; Barrera, Francisco N; Deacon, John C; Bo ... R01ES005775 Mol Pharm (2020 02 03) 31855437 Exiting the NIEHS site 2020 
Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki f ...   Thakar, Tanay; Leung, Wendy; Nicolae, Claudia M; Clements, Kristen E; Shen, Binghui; Bielinsky, ... R01ES026184 Nat Commun (2020 05 01) 32358495 Exiting the NIEHS site 2020 
Unhooking of an interstrand cross-link at DNA fork structures by the DNA glycosylase NEIL3.   Imani Nejad, Maryam; Housh, Kurt; Rodriguez, Alyssa A; Haldar, Tuhin; Kathe, Scott; Wallace, S ... R01ES021007 DNA Repair (Amst) (2020 02) 31923807 Exiting the NIEHS site 2020 
USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced ...   Zhu, Qianzheng; Ding, Nan; Wei, Shengcai; Li, Ping; Wani, Gulzar; He, Jinshan; Wani, Altaf A R01ES012991 Cell Cycle (2020 01) 31775559 Exiting the NIEHS site 2020 
Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Impli ...   Cai, Yuqin; Geacintov, Nicholas E; Broyde, Suse R01ES025987 DNA Repair (Amst) (2020 03) 32018112 Exiting the NIEHS site 2020 
YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA.   Dai, Xiaoxia; Gonzalez, Gwendolyn; Li, Lin; Li, Jie; You, Changjun; Miao, Weili; Hu, Junchi; ... R01ES025121, T32ES018827 Anal Chem (2020 01 07) 31815440 Exiting the NIEHS site 2020 
5',8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significanc ...   Chatgilialoglu, Chryssostomos; Ferreri, Carla; Geacintov, Nicholas E; Krokidis, Marios G; Liu, ... R01ES023569, R01ES027059 Cells (2019 05 28) 31141888 Exiting the NIEHS site 2019 
5-Formylcytosine-induced DNA-peptide cross-links reduce transcription efficiency, but do not cause t ...   Ji, Shaofei; Park, Daeyoon; Kropachev, Konstantin; Kolbanovskiy, Marina; Fu, Iwen; Broyde, Sus ... R01ES023350, R01ES025987 J Biol Chem (2019 11 29) 31597704 Exiting the NIEHS site 2019 
A parametric meta-analysis.   Yu, Chang; Zelterman, Daniel R01ES005775 Stat Med (2019 09 20) 31206759 Exiting the NIEHS site 2019 
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.   Xing, Xuanxuan; Kane, Daniel P; Bulock, Chelsea R; Moore, Elizabeth A; Sharma, Sushma; Chabes, ... R01ES015869 Nat Commun (2019 01 22) 30670691 Exiting the NIEHS site 2019 
A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.   Wojtaszek, Jessica L; Chatterjee, Nimrat; Najeeb, Javaria; Ramos, Azucena; Lee, Minhee; Bian, ... R01ES028865, R01ES028865, R35ES028303 Cell (2019 06 27) 31178121 Exiting the NIEHS site 2019 
A two-stage phase II clinical trial design with nested criteria for early stopping and efficacy.   DeVeaux, Michelle; Kane, Michael; Wei, Wei; Zelterman, Daniel R01ES005775, R01ES019179 Pharm Stat (2019 11) 31507079 Exiting the NIEHS site 2019 
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.   Yang, Jason H; Wright, Sarah N; Hamblin, Meagan; McCloskey, Douglas; Alcantar, Miguel A; Schrüb ... R35ES028303 Cell (2019 05 30) 31080069 Exiting the NIEHS site 2019 
Aberrant Activation of β-Catenin Signaling Drives Glioma Tumorigenesis via USP1-Mediated Stabilizati ...   Ma, Li; Lin, Kangyu; Chang, Guoqiang; Chen, Yiwen; Yue, Chen; Guo, Qing; Zhang, Sicong; Jia, ... R01ES025166 Cancer Res (2019 01 01) 30425057 Exiting the NIEHS site 2019 
Accelerating cancer without mutations.   Brash, Douglas E R01ES030562 Elife (2019 03 21) 30895924 Exiting the NIEHS site 2019 
Addendum: Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA.   Koh, Kyung Duk; Balachander, Sathya; Hesselberth, Jay R; Storici, Francesca R01ES026243 Nat Methods (2019 08) 31324896 Exiting the NIEHS site 2019 
Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo a ...   Coskun, Erdem; Jaruga, Pawel; Vartanian, Vladimir; Erdem, Onur; Egner, Patricia A; Groopman, J ... R01ES031086 Chem Res Toxicol (2019 01 22) 30525498 Exiting the NIEHS site 2019 
AID-RNA polymerase II transcription-dependent deamination of IgV DNA.   Pham, Phuong; Malik, Sohail; Mak, Chiho; Calabrese, Peter C; Roeder, Robert G; Goodman, Myron ... R35ES028343 Nucleic Acids Res (2019 11 18) 31566237 Exiting the NIEHS site 2019 
Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral ...   Watt, Gordon P; Reiner, Anne S; Smith, Susan A; Stram, Daniel O; Capanu, Marinela; Malone, Kat ... R01ES027121 JAMA Netw Open (2019 09 04) 31560388 Exiting the NIEHS site 2019 
Associations of Benzo(ghi)perylene and Heptachlorodibenzo-p-dioxin in Serum of Service Personnel Dep ...   Smith, Matthew Ryan; Woeller, Collynn F; Uppal, Karan; Thatcher, Thomas H; Walker, Douglas I; H ... P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800449 Exiting the NIEHS site 2019 
Benzo[a]pyrene Perturbs Mitochondrial and Amino Acid Metabolism in Lung Epithelial Cells and Has Sim ...   Smith, Matthew Ryan; Walker, Douglas I; Uppal, Karan; Utell, Mark J; Hopke, Philip K; Mallon, ... P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800453 Exiting the NIEHS site 2019 
Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole ...   Bellamri, Medjda; Yao, Lihua; Bonala, Radha; Johnson, Francis; Von Weymarn, Linda B; Turesky, ... R01ES019564, R01ES030559 Arch Toxicol (2019 07) 31203411 Exiting the NIEHS site 2019 
Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner.   Bian, Ke; Delaney, James C; Zhou, Xianhao; Li, Deyu R01ES028865, R01ES028865 Toxics (2019 Jun 25) 31242562 Exiting the NIEHS site 2019 
Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase η.   Koag, Myong-Chul; Jung, Hunmin; Kou, Yi; Lee, Seongmin R01ES026676 Molecules (2019 Oct 31) 31683505 Exiting the NIEHS site 2019 
Capture of Ribonucleotides in Yeast Genomic DNA Using Ribose-Seq.   Balachander, Sathya; Yang, Taehwan; Newnam, Gary; El-Sayed, Waleed M M; Koh, Kyung Duk; Storici ... R01ES026243 Methods Mol Biol (2019) 31602603 Exiting the NIEHS site 2019 
Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51.   Kaplan, Alanna R; Gueble, Susan E; Liu, Yanfeng; Oeck, Sebastian; Kim, Hoon; Yun, Zhong; Glaze ... R01ES005775 Sci Transl Med (2019 05 15) 31092693 Exiting the NIEHS site 2019 
Characterization of rare NEIL1 variants found in East Asian populations.   Minko, Irina G; Vartanian, Vladimir L; Tozaki, Naoto N; Linde, Oskar K; Jaruga, Pawel; Coskun, ... R01ES029357 DNA Repair (Amst) (2019 07) 31100703 Exiting the NIEHS site 2019 
Conformational regulation of Escherichia coli DNA polymerase V by RecA and ATP.   Jaszczur, Malgorzata M; Vo, Dan D; Stanciauskas, Ramunas; Bertram, Jeffrey G; Sikand, Adhirath; ... R35ES028343 PLoS Genet (2019 02) 30716079 Exiting the NIEHS site 2019 
Damage sensor role of UV-DDB during base excision repair.   Jang, Sunbok; Kumar, Namrata; Beckwitt, Emily C; Kong, Muwen; Fouquerel, Elise; Rapić-Otrin, V ... R01ES019566, R33ES025606, T32ES007059 Nat Struct Mol Biol (2019 08) 31332353 Exiting the NIEHS site 2019 
Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts.   Biswas, Himadri; Goto, Greicy; Wang, Weibin; Sung, Patrick; Sugimoto, Katsunori R01ES007061 PLoS Genet (2019 08) 31369547 Exiting the NIEHS site 2019 
Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination.   Steinfeld, Justin B; Beláň, Ondrej; Kwon, Youngho; Terakawa, Tsuyoshi; Al-Zain, Amr; Smith, Mi ... R01ES007061 Genes Dev (2019 09 01) 31371435 Exiting the NIEHS site 2019 
Diastereomeric Recognition of 5',8-cyclo-2'-Deoxyadenosine Lesions by Human Poly(ADP-ribose) Polymer ...   Masi, Annalisa; Sabbia, Arianna; Ferreri, Carla; Manoli, Francesco; Lai, Yanhao; Laverde, Edua ... R01ES023569 Cells (2019 02 02) 30717407 Exiting the NIEHS site 2019 
Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse org ...   Yimit, Askar; Adebali, Ogun; Sancar, Aziz; Jiang, Yuchao P30ES010126, R01ES027255 Nat Commun (2019 01 18) 30659176 Exiting the NIEHS site 2019 
Distinct Binding Modes of Vinculin Isoforms Underlie Their Functional Differences.   Krokhotin, Andrey; Sarker, Muzaddid; Sevilla, Ernesto Alva; Costantini, Lindsey M; Griffith, Ja ... R56ES013773 Structure (2019 10 01) 31422909 Exiting the NIEHS site 2019 
DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Res ...   Hu, Chiung-Wen; Chang, Yuan-Jhe; Cooke, Marcus S; Chao, Mu-Rong R01ES030557 Anal Chem (2019 12 03) 31670503 Exiting the NIEHS site 2019 
DNA polymerase θ accomplishes translesion synthesis opposite 1,N6-ethenodeoxyadenosine with a remark ...   Yoon, Jung-Hoon; Johnson, Robert E; Prakash, Louise; Prakash, Satya R01ES022948 Genes Dev (2019 03 01) 30808656 Exiting the NIEHS site 2019 
DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-f ...   Bian, Ke; Lenz, Stefan A P; Tang, Qi; Chen, Fangyi; Qi, Rui; Jost, Marco; Drennan, Catherine ... P30ES002109, R01ES028865, R01ES028865 Nucleic Acids Res (2019 06 20) 31114894 Exiting the NIEHS site 2019 
DNA replication studies of N-nitroso compound-induced O6-alkyl-2'-deoxyguanosine lesions in Escheric ...   Wang, Pengcheng; Leng, Jiapeng; Wang, Yinsheng R01ES025121 J Biol Chem (2019 03 15) 30655287 Exiting the NIEHS site 2019 
DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage re ...   Liang, Fengshan; Miller, Adam S; Longerich, Simonne; Tang, Caroline; Maranon, David; Williamson ... R01ES007061 Nat Commun (2019 06 28) 31253762 Exiting the NIEHS site 2019 
Drosophila, which lacks canonical transcription-coupled repair proteins, performs transcription-coup ...   Deger, Nazli; Yang, Yanyan; Lindsey-Boltz, Laura A; Sancar, Aziz; Selby, Christopher P R01ES027255 J Biol Chem (2019 11 29) 31624146 Exiting the NIEHS site 2019 
Dual regulation of Arabidopsis AGO2 by arginine methylation.   Hu, Po; Zhao, Hongwei; Zhu, Pei; Xiao, Yongsheng; Miao, Weili; Wang, Yinsheng; Jin, Hailing R01ES025121 Nat Commun (2019 02 19) 30783097 Exiting the NIEHS site 2019 
Dynamic interactions of the homologous pairing 2 (Hop2)-meiotic nuclear divisions 1 (Mnd1) protein c ...   Crickard, J Brooks; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2019 01 11) 30420424 Exiting the NIEHS site 2019 
Environmental Cadmium Enhances Lung Injury by Respiratory Syncytial Virus Infection.   Hu, Xin; Kim, Ki-Hye; Lee, Youri; Fernandes, Jolyn; Smith, M Ryan; Jung, Yu-Jin; Orr, Michael ... P30ES019776, R01ES023485 Am J Pathol (2019 08) 31108100 Exiting the NIEHS site 2019 
Environmental Chemicals Altered in Association With Deployment for High Risk Areas.   Smith, Matthew Ryan; Uppal, Karan; Walker, Douglas I; Utell, Mark J; Hopke, Philip K; Mallon, ... P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800447 Exiting the NIEHS site 2019 
Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cells.   Naldiga, Spandana; Ji, Shaofei; Thomforde, Jenna; Nicolae, Claudia M; Lee, Marietta; Zhang, Zh ... R01ES023350, R01ES026184 J Biol Chem (2019 07 05) 31138652 Exiting the NIEHS site 2019 
Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers.   Yoon, Jung-Hoon; McArthur, Mark J; Park, Jeseong; Basu, Debashree; Wakamiya, Maki; Prakash, Lo ... R01ES022948 Cell (2019 03 07) 30773314 Exiting the NIEHS site 2019 
Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay.   Karbaschi, Mahsa; Ji, Yunhee; Abdulwahed, Abdulhadi Mohammed S; Alohaly, Alhanoof; Bedoya, Juan ... R41ES030274 Int J Mol Sci (2019 Dec 02) 31810189 Exiting the NIEHS site 2019 
Excision of Oxidatively Generated Guanine Lesions by Competing Base and Nucleotide Excision Repair M ...   Shafirovich, Vladimir; Kropachev, Konstantin; Kolbanovskiy, Marina; Geacintov, Nicholas E R01ES027059 Chem Res Toxicol (2019 04 15) 30688445 Exiting the NIEHS site 2019 
Fluorescent 5-Pyrimidine and 8-Purine Nucleosides Modified with an N-Unsubstituted 1,2,3-Triazol-4-y ...   Wen, Zhiwei; Tuttle, Paloma R; Howlader, A Hasan; Vasilyeva, Anna; Gonzalez, Laura; Tangar, An ... R01ES023569 J Org Chem (2019 03 15) 30806513 Exiting the NIEHS site 2019 
Generation of 8-oxo-7,8-dihydroguanine in G-Quadruplexes Models of Human Telomere Sequences by One-e ...   Merta, Tomasz J; Geacintov, Nicholas E; Shafirovich, Vladimir R01ES027059 Photochem Photobiol (2019 01) 29679477 Exiting the NIEHS site 2019 
Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thym ...   Alhegaili, Alaa S; Ji, Yunhee; Sylvius, Nicolas; Blades, Matthew J; Karbaschi, Mahsa; Tempest, ... R15ES027196, R15ES027196 Int J Mol Sci (2019 Oct 15) 31618917 Exiting the NIEHS site 2019 
Genome-wide mapping of nucleotide excision repair with XR-seq.   Hu, Jinchuan; Li, Wentao; Adebali, Ogun; Yang, Yanyan; Oztas, Onur; Selby, Christopher P; Sanc ... P30ES010126, R01ES027255 Nat Protoc (2019 01) 30552409 Exiting the NIEHS site 2019 
Genomic sites hypersensitive to ultraviolet radiation.   Premi, Sanjay; Han, Lynn; Mehta, Sameet; Knight, James; Zhao, Dejian; Palmatier, Meg A; Kornac ... R01ES030562 Proc Natl Acad Sci U S A (2019 11 26) 31723047 Exiting the NIEHS site 2019 
Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes.   Klein, Hannah L; Ang, Kenny K H; Arkin, Michelle R; Beckwitt, Emily C; Chang, Yi-Hsuan; Fan, J ... R01ES007061 Microb Cell (2019 Jan 07) 30652106 Exiting the NIEHS site 2019 
GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation.   Terao, Chikashi; Momozawa, Yukihide; Ishigaki, Kazuyoshi; Kawakami, Eiryo; Akiyama, Masato; Loh ... DP2ES030554 Nat Commun (2019 10 17) 31624269 Exiting the NIEHS site 2019 
High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation.   Oeck, Sebastian; Malewicz, Nathalie M; Krysztofiak, Adam; Turchick, Audrey; Jendrossek, Verena; ... R01ES005775 Sci Rep (2019 02 28) 30816253 Exiting the NIEHS site 2019 
Human DNA polymerase η has reverse transcriptase activity in cellular environments.   Su, Yan; Ghodke, Pratibha P; Egli, Martin; Li, Lin; Wang, Yinsheng; Guengerich, F Peter R01ES010546, R01ES025121, R01ES026955 J Biol Chem (2019 04 12) 30842261 Exiting the NIEHS site 2019 
Hydrolyzable Tannins Are Iron Chelators That Inhibit DNA Repair Enzyme ALKBH2.   Chen, Fangyi; Tang, Qi; Ma, Hang; Bian, Ke; Seeram, Navindra P; Li, Deyu R01ES028865, R01ES028865 Chem Res Toxicol (2019 06 17) 31088072 Exiting the NIEHS site 2019 
Identification of charged amino acids required for nuclear localization of human L1 ORF1 protein.   Freeman, B T; Sokolowski, M; Roy-Engel, A M; Smither, M E; Belancio, V P R21ES027797 Mob DNA (2019) 31080522 Exiting the NIEHS site 2019 
Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Va ...   Thakar, Juilee; Thatcher, Thomas H; Smith, Matthew Ryan; Woeller, Collynn F; Walker, Douglas I; ... P30ES001247, P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800452 Exiting the NIEHS site 2019 
Long-term, genome-wide kinetic analysis of the effect of the circadian clock and transcription on th ...   Yang, Yanyan; Liu, Zhenxing; Selby, Christopher P; Sancar, Aziz P30ES010126, R01ES027255 J Biol Chem (2019 08 09) 31217280 Exiting the NIEHS site 2019 
Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung.   Hu, Xin; Chandler, Joshua D; Park, Soojin; Liu, Ken; Fernandes, Jolyn; Orr, Michael; Smith, M ... P30ES019776, R01ES023485, U2CES026560 Free Radic Biol Med (2019 02 01) 30529385 Exiting the NIEHS site 2019 
Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in mic ...   Chandler, Joshua D; Hu, Xin; Ko, Eun-Ju; Park, Soojin; Fernandes, Jolyn; Lee, Young-Tae; Orr, ... R01ES023485 Environ Int (2019 06) 30999129 Exiting the NIEHS site 2019 
Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleo ...   Rai, Priyamvada; Sobol, Robert W P01ES028949, R01ES014811, U01ES029518, U01ES029518 DNA Repair (Amst) (2019 05) 30852368 Exiting the NIEHS site 2019 
Mechanisms underlying aflatoxin-associated mutagenesis - Implications in carcinogenesis.   McCullough, Amanda K; Lloyd, R Stephen R01ES029357 DNA Repair (Amst) (2019 05) 30897375 Exiting the NIEHS site 2019 
Mechanistic Study of TTF-1 Modulation of Cellular Sensitivity to Cisplatin.   Phelps, Cody A; Lindsey-Boltz, Laura; Sancar, Aziz; Mu, David P30ES010126, R01ES027255 Sci Rep (2019 05 29) 31142791 Exiting the NIEHS site 2019 
Metabolic perturbations in classic galactosemia beyond the Leloir pathway: Insights from an untarget ...   Taylor Fischer, S; Frederick, Allison B; Tran, ViLinh; Li, Shuzhao; Jones, Dean P; Fridovich-Ke ... P30ES019776, R01ES023485 J Inherit Metab Dis (2019 03) 30667068 Exiting the NIEHS site 2019 
Metabolome-Wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan.   Go, Young-Mi; Smith, Matthew R; Walker, Douglas I; Uppal, Karan; Rohrbeck, Patricia; Krahl, Pa ... P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800448 Exiting the NIEHS site 2019 
Metabolomic assessment of exposure to near-highway ultrafine particles.   Walker, Douglas I; Lane, Kevin J; Liu, Ken; Uppal, Karan; Patton, Allison P; Durant, John L; J ... P30ES019776, R01ES023485 J Expo Sci Environ Epidemiol (2019 06) 30518795 Exiting the NIEHS site 2019 
Metabolomic Responses to Manganese Dose in SH-SY5Y Human Neuroblastoma Cells.   Fernandes, Jolyn; Chandler, Joshua D; Liu, Ken H; Uppal, Karan; Hao, Li; Hu, Xin; Go, Young-M ... P30ES019776, R01ES023485 Toxicol Sci (2019 05 01) 30715528 Exiting the NIEHS site 2019 
Methods to Study Trinucleotide Repeat Instability Induced by DNA Damage and Repair.   Lai, Yanhao; Lei, Ruipeng; Ren, Yaou; Liu, Yuan R01ES023569 Methods Mol Biol (2019) 31127571 Exiting the NIEHS site 2019 
MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.   Srinivasan, Gayathri; Williamson, Elizabeth A; Kong, Kimi; Jaiswal, Aruna S; Huang, Guangcun; K ... R01ES007061 Proc Natl Acad Sci U S A (2019 08 27) 31395736 Exiting the NIEHS site 2019 
Mitochondria in precision medicine; linking bioenergetics and metabolomics in platelets.   Chacko, Balu K; Smith, Matthew R; Johnson, Michelle S; Benavides, Gloria; Culp, Matilda L; Pill ... P30ES019776, R01ES023485, U2CES026560 Redox Biol (2019 04) 30877854 Exiting the NIEHS site 2019 
Mitochondrial DNA: Epigenetics and environment.   Sharma, Nidhi; Pasala, Monica S; Prakash, Aishwarya R01ES030084, R01ES030084 Environ Mol Mutagen (2019 10) 31335990 Exiting the NIEHS site 2019 
Mitotic DNA Synthesis Is Differentially Regulated between Cancer and Noncancerous Cells.   Graber-Feesl, Cari L; Pederson, Kayla D; Aney, Katherine J; Shima, Naoko R21ES027062 Mol Cancer Res (2019 08) 31113828 Exiting the NIEHS site 2019 
Murine models of accelerated aging and musculoskeletal disease.   Hambright, William S; Niedernhofer, Laura J; Huard, Johnny; Robbins, Paul D U01ES029603 Bone (2019 08) 30844492 Exiting the NIEHS site 2019 
Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Po ...   Koag, Myong-Chul; Jung, Hunmin; Lee, Seongmin R01ES026676 J Am Chem Soc (2019 03 20) 30817143 Exiting the NIEHS site 2019 
Mycoplasma infection of cultured cells induces oxidative stress and attenuates cellular base excisio ...   Ji, Yunhee; Karbaschi, Mahsa; Cooke, Marcus S R15ES027196, R15ES027196 Mutat Res (2019 09) 31561888 Exiting the NIEHS site 2019 
N-Acetylcysteine: Antioxidant, Aldehyde Scavenger, and More.   Zhitkovich, Anatoly R01ES008786, R01ES028072 Chem Res Toxicol (2019 07 15) 31046246 Exiting the NIEHS site 2019 
NuA4 acetyltransferase is required for efficient nucleotide excision repair in yeast.   Hodges, Amelia J; Plummer, Dalton A; Wyrick, John J R01ES028698 DNA Repair (Amst) (2019 01) 30473425 Exiting the NIEHS site 2019 
Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the ...   Shafirovich, Vladimir; Kolbanovskiy, Marina; Kropachev, Konstantin; Liu, Zhi; Cai, Yuquin; Terz ... R01ES025987 Biochemistry (2019 02 12) 30570250 Exiting the NIEHS site 2019 
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma ce ...   Li, Wentao; Liu, Wenjie; Kakoki, Ayano; Wang, Rujin; Adebali, Ogun; Jiang, Yuchao; Sancar, Az ... P30ES010126, R01ES027255 J Biol Chem (2019 04 12) 30808711 Exiting the NIEHS site 2019 
Organization of DNA damage, excision repair, and mutagenesis in chromatin: A genomic perspective.   Mao, Peng; Wyrick, John J R01ES028698, R21ES029302, R21ES029655 DNA Repair (Amst) (2019 09) 31307926 Exiting the NIEHS site 2019 
p53 activation by Cr(VI): a transcriptionally limited response induced by ATR kinase in S-phase.   Luczak, Michal W; Krawic, Casey; Zhitkovich, Anatoly R01ES008786, R01ES028072 Toxicol Sci (2019 Aug 06) 31388677 Exiting the NIEHS site 2019 
Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental meta ...   Dennis, Kristine K; Uppal, Karan; Liu, Ken H; Ma, Chunyu; Liang, Bill; Go, Young-Mi; Jones, D ... P30ES019776, R01ES023485, U2CES030163 Database (Oxford) (2019 01 01) 31267134 Exiting the NIEHS site 2019 
POLE proofreading defects: Contributions to mutagenesis and cancer.   Park, Vivian S; Pursell, Zachary F R01ES028271 DNA Repair (Amst) (2019 04) 30818169 Exiting the NIEHS site 2019 
Probing the Effect of Bulky Lesion-Induced Replication Fork Conformational Heterogeneity Using 4-Ami ...   Cai, Ang; Bian, Ke; Chen, Fangyi; Tang, Qi; Carley, Rachel; Li, Deyu; Cho, Bongsup P R01ES028865, R01ES028865 Molecules (2019 Apr 20) 31009995 Exiting the NIEHS site 2019 
Processing of N5-substituted formamidopyrimidine DNA adducts by DNA glycosylases NEIL1 and NEIL3.   Minko, Irina G; Christov, Plamen P; Li, Liang; Stone, Michael P; McCullough, Amanda K; Lloyd, ... R01ES029357, T32ES007020 DNA Repair (Amst) (2019 01) 30448017 Exiting the NIEHS site 2019 
Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.   Kou, Yi; Koag, Myong-Chul; Lee, Seongmin R01ES026676 Molecules (2019 Sep 27) 31569643 Exiting the NIEHS site 2019 
Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link.   Thompson, Petria S; Amidon, Katherine M; Mohni, Kareem N; Cortez, David; Eichman, Brandt F R01ES030575 Nat Struct Mol Biol (2019 07) 31235915 Exiting the NIEHS site 2019 
Quantification of DNA Lesions Induced by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Mammalian ...   Guo, Su; Leng, Jiapeng; Tan, Ying; Price, Nathan E; Wang, Yinsheng R01ES025121, T32ES018827 Chem Res Toxicol (2019 04 15) 30714728 Exiting the NIEHS site 2019 
R-loop formation by dCas9 is mutagenic in Saccharomyces cerevisiae.   Laughery, Marian F; Mayes, Hannah C; Pedroza, Ivan K; Wyrick, John J R01ES028698 Nucleic Acids Res (2019 03 18) 30590793 Exiting the NIEHS site 2019 
Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast.   Yan, Zhenxin; Xue, Chaoyou; Kumar, Sandeep; Crickard, J Brooks; Yu, Yang; Wang, Weibin; Pham, ... R01ES007061 Mol Cell (2019 12 05) 31542296 Exiting the NIEHS site 2019 
Random Walk Enzymes: Information Theory, Quantum Isomorphism, and Entropy Dispersion.   Mak, Chi H; Pham, Phuong; Goodman, Myron F R35ES028343 J Phys Chem A (2019 Apr 04) 30848911 Exiting the NIEHS site 2019 
Recurrent Noncoding Mutations in Skin Cancers: UV Damage Susceptibility or Repair Inhibition as Prim ...   Roberts, Steven A; Brown, Alexander J; Wyrick, John J R01ES028698, R21ES029302 Bioessays (2019 03) 30801747 Exiting the NIEHS site 2019 
Redox Systems Biology of Nutrition and Oxidative Stress.   Dennis, Kristine K; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485 J Nutr (2019 04 01) 30949678 Exiting the NIEHS site 2019 
Regulatory control of Sgs1 and Dna2 during eukaryotic DNA end resection.   Xue, Chaoyou; Wang, Weibin; Crickard, J Brooks; Moevus, Corentin J; Kwon, Youngho; Sung, Patri ... R01ES007061 Proc Natl Acad Sci U S A (2019 03 26) 30850524 Exiting the NIEHS site 2019 
Repair and translesion synthesis of O6-alkylguanine DNA lesions in human cells.   Du, Hua; Wang, Pengcheng; Li, Lin; Wang, Yinsheng R01ES025121 J Biol Chem (2019 07 19) 31167778 Exiting the NIEHS site 2019 
Replication Stress and Consequential Instability of the Genome and Epigenome.   Tsegay, Pawlos S; Lai, Yanhao; Liu, Yuan R01ES023569 Molecules (2019 Oct 27) 31717862 Exiting the NIEHS site 2019 
Replication-Coupled DNA Repair.   Cortez, David R01ES030575 Mol Cell (2019 06 06) 31173722 Exiting the NIEHS site 2019 
Ribose-Map: a bioinformatics toolkit to map ribonucleotides embedded in genomic DNA.   Gombolay, Alli L; Vannberg, Fredrik O; Storici, Francesca R01ES026243 Nucleic Acids Res (2019 01 10) 30272244 Exiting the NIEHS site 2019 
Ribosomal DNA and the Nucleolus as Keystones of Nuclear Architecture, Organization, and Function.   Cerqueira, Amanda V; Lemos, Bernardo R01ES027981 Trends Genet (2019 10) 31447250 Exiting the NIEHS site 2019 
Ribosomal DNA harbors an evolutionarily conserved clock of biological aging.   Wang, Meng; Lemos, Bernardo P30ES000002, R01ES027981 Genome Res (2019 03) 30765617 Exiting the NIEHS site 2019 
Role of RNase H enzymes in maintaining genome stability in Escherichia coli expressing a steric-gate ...   Walsh, Erin; Henrikus, Sarah S; Vaisman, Alexandra; Makiela-Dzbenska, Karolina; Armstrong, Thom ... R35ES028343 DNA Repair (Amst) (2019 12) 31543434 Exiting the NIEHS site 2019 
Role of Y-family translesion DNA polymerases in replication stress: Implications for new cancer ther ...   Tonzi, Peter; Huang, Tony T R01ES025166 DNA Repair (Amst) (2019 06) 30954011 Exiting the NIEHS site 2019 
Rotational and translational positions determine the structural and dynamic impact of a single ribon ...   Fu, Iwen; Smith, Duncan J; Broyde, Suse R01ES025987 DNA Repair (Amst) (2019 01) 30522887 Exiting the NIEHS site 2019 
Sense and sensibility: ATM oxygen stress signaling manages brain cell energetics.   Schlacher, Katharina R01ES029680 J Cell Biol (2019 03 04) 30782782 Exiting the NIEHS site 2019 
Simple CRISPR-Cas9 Genome Editing in Saccharomyces cerevisiae.   Laughery, Marian F; Wyrick, John J R01ES028698, R21ES029302, R21ES029655 Curr Protoc Mol Biol (2019 12) 31763795 Exiting the NIEHS site 2019 
Single-molecule visualization of human BLM helicase as it acts upon double- and single-stranded DNA ...   Xue, Chaoyou; Daley, James M; Xue, Xiaoyu; Steinfeld, Justin; Kwon, Youngho; Sung, Patrick; Gr ... R01ES007061 Nucleic Acids Res (2019 12 02) 31544923 Exiting the NIEHS site 2019 
Single-nucleotide resolution analysis of nucleotide excision repair of ribosomal DNA in humans and m ...   Yang, Yanyan; Hu, Jinchuan; Selby, Christopher P; Li, Wentao; Yimit, Askar; Jiang, Yuchao; San ... P30ES010126, R01ES027255 J Biol Chem (2019 01 04) 30413533 Exiting the NIEHS site 2019 
SLIRP Interacts with Helicases to Facilitate 2'-O-Methylation of rRNA and to Promote Translation.   Li, Lin; Miao, Weili; Williams, Preston; Guo, Cheng; Wang, Yinsheng R01ES025121 J Am Chem Soc (2019 07 17) 31260285 Exiting the NIEHS site 2019 
Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase η.   Ouzon-Shubeita, Hala; Baker, Meghan; Koag, Myong-Chul; Lee, Seongmin R01ES026676 Biochem J (2019 02 28) 30709915 Exiting the NIEHS site 2019 
Structural consequence of the most frequently recurring cancer-associated substitution in DNA polyme ...   Parkash, Vimal; Kulkarni, Yashraj; Ter Beek, Josy; Shcherbakova, Polina V; Kamerlin, Shina Caro ... R01ES015869 Nat Commun (2019 01 22) 30670696 Exiting the NIEHS site 2019 
Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucl ...   Paul, Debamita; Mu, Hong; Zhao, Hong; Ouerfelli, Ouathek; Jeffrey, Philip D; Broyde, Suse; Min ... R01ES025987, R21ES028384 Nucleic Acids Res (2019 07 09) 31106376 Exiting the NIEHS site 2019 
Synthesis and Characterization of Site-Specific O6 -Alkylguanine DNA-Alkyl Transferase-Oligonucleoti ...   Ghodke, Pratibha P; Albertolle, Matthew E; Johnson, Kevin M; Guengerich, F Peter R01ES010546, R01ES026955 Curr Protoc Nucleic Acid Chem (2019 03) 30657645 Exiting the NIEHS site 2019 
Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis.   Fouquerel, Elise; Barnes, Ryan P; Uttam, Shikhar; Watkins, Simon C; Bruchez, Marcel P; Opresko, ... R00ES027028, R33ES025606 Mol Cell (2019 07 11) 31101499 Exiting the NIEHS site 2019 
Targeted Quantitative Proteomic Approach for High-Throughput Quantitative Profiling of Small GTPases ...   Huang, Ming; Darvas, Martin; Keene, C Dirk; Wang, Yinsheng R01ES025121, T32ES018827 Anal Chem (2019 10 01) 31460748 Exiting the NIEHS site 2019 
Targeted Quantitative Proteomics Revealed Arsenite-induced Proteasomal Degradation of RhoB in Fibrob ...   Tam, Lok Ming; Huang, Ming; Wang, Yinsheng R01ES025121, T32ES018827 Chem Res Toxicol (2019 07 15) 31140275 Exiting the NIEHS site 2019 
Targeting phosphatases in cancer: suppression of many versus the ablation of one.   D'Arcy, Brandon M; Prakash, Aishwarya; Honkanen, Richard E R01ES030084, R01ES030084 Oncotarget (2019 Nov 12) 31762936 Exiting the NIEHS site 2019 
The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.   Zhao, Weixing; Wiese, Claudia; Kwon, Youngho; Hromas, Robert; Sung, Patrick R01ES007061 Annu Rev Biochem (2019 06 20) 30917004 Exiting the NIEHS site 2019 
The Impact of Minor-Groove N2-Alkyl-2'-deoxyguanosine Lesions on DNA Replication in Human Cells.   Wu, Jun; Du, Hua; Li, Lin; Price, Nathan E; Liu, Xiaochuan; Wang, Yinsheng R01ES025121, T32ES018827 ACS Chem Biol (2019 08 16) 31347832 Exiting the NIEHS site 2019 
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.   Rosenbaum, Joel C; Bonilla, Braulio; Hengel, Sarah R; Mertz, Tony M; Herken, Benjamin W; Kazemi ... R01ES007061, R01ES019566 Nat Commun (2019 08 05) 31383866 Exiting the NIEHS site 2019 
The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments.   Crickard, J Brooks; Xue, Chaoyou; Wang, Weibin; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Nucleic Acids Res (2019 05 21) 30916344 Exiting the NIEHS site 2019 
Transcription shapes DNA replication initiation and termination in human cells.   Chen, Yu-Hung; Keegan, Sarah; Kahli, Malik; Tonzi, Peter; Fenyö, David; Huang, Tony T; Smith, ... R01ES025166 Nat Struct Mol Biol (2019 01) 30598550 Exiting the NIEHS site 2019 
Transcriptional Bypass of DNA-Protein and DNA-Peptide Conjugates by T7 RNA Polymerase.   Ji, Shaofei; Thomforde, Jenna; Rogers, Colette; Fu, Iwen; Broyde, Suse; Tretyakova, Natalia Y R01ES023350, R01ES025987 ACS Chem Biol (2019 12 20) 31573793 Exiting the NIEHS site 2019 
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in ...   Fernandes, Jolyn; Chandler, Joshua D; Lili, Loukia N; Uppal, Karan; Hu, Xin; Hao, Li; Go, You ... P30ES019776, R01ES023485 Front Genet (2019) 31396262 Exiting the NIEHS site 2019 
Unlike the Escherichia coli counterpart, archaeal RNase HII cannot process ribose monophosphate abas ...   Malfatti, Matilde Clarissa; Henneke, Ghislaine; Balachander, Sathya; Koh, Kyung Duk; Newnam, Ga ... R01ES026243 J Biol Chem (2019 08 30) 31300556 Exiting the NIEHS site 2019 
Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev1-CT/RIR Protein-Prot ...   Dash, Radha C; Ozen, Zuleyha; McCarthy, Kaitlyn R; Chatterjee, Nimrat; Harris, Cynthia A; Rizzo ... P30ES002109, R35ES028303 ChemMedChem (2019 09 04) 31361935 Exiting the NIEHS site 2019 
Vitamin C as a Modulator of the Response to Cancer Therapy.   Blaszczak, Wiktoria; Barczak, Wojciech; Masternak, Julia; Kopczyński, Przemysław; Zhitkovich, A ... R01ES008786 Molecules (2019 Jan 28) 30695991 Exiting the NIEHS site 2019 
Vitamin C increases DNA breaks and suppresses DNA damage-independent activation of ATM by bleomycin.   Rubis, Blazej; Luczak, Michal W; Krawic, Casey; Zhitkovich, Anatoly R01ES008786, R01ES028072 Free Radic Biol Med (2019 05 20) 30926564 Exiting the NIEHS site 2019 
5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in huma ...   Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... R01ES023350, R01ES025987 Nucleic Acids Res (2018 07 27) 29905846 Exiting the NIEHS site 2018 
A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) o ...   Wang, Weibin; Daley, James M; Kwon, Youngho; Xue, Xiaoyu; Krasner, Danielle S; Miller, Adam S; ... R01ES007061 J Biol Chem (2018 11 02) 30224356 Exiting the NIEHS site 2018 
A new mitotic activity comes into focus.   Saldivar, Joshua C; Cimprich, Karlene A R01ES016486 Science (2018 01 05) 29302000 Exiting the NIEHS site 2018 
A quantitative PCR-based assay reveals that nucleotide excision repair plays a predominant role in t ...   Chesner, Lisa N; Campbell, Colin R01ES023350 DNA Repair (Amst) (2018 02) 29413806 Exiting the NIEHS site 2018 
An intrinsic S/G2 checkpoint enforced by ATR.   Saldivar, Joshua C; Hamperl, Stephan; Bocek, Michael J; Chung, Mingyu; Bass, Thomas E; Cisneros ... R01ES016486 Science (2018 08 24) 30139873 Exiting the NIEHS site 2018 
An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleot ...   Beaver, Jill M; Lai, Yanhao; Rolle, Shantell J; Weng, Liwei; Greenberg, Marc M; Liu, Yuan R01ES023569 PLoS One (2018) 29389977 Exiting the NIEHS site 2018 
Arsenite Targets the RING Finger Domain of Rbx1 E3 Ubiquitin Ligase to Inhibit Proteasome-Mediated D ...   Jiang, Ji; Tam, Lok Ming; Wang, Pengcheng; Wang, Yinsheng R01ES025121 Chem Res Toxicol (2018 05 21) 29658272 Exiting the NIEHS site 2018 
Cisplatin-DNA adduct repair of transcribed genes is controlled by two circadian programs in mouse ti ...   Yang, Yanyan; Adebali, Ogun; Wu, Gang; Selby, Christopher P; Chiou, Yi-Ying; Rashid, Naim; Hu, ... P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2018 05 22) 29735688 Exiting the NIEHS site 2018 
Comparative properties and functions of type 2 and type 4 pigeon cryptochromes.   Wang, Xuefeng; Jing, Chengyu; Selby, Christopher P; Chiou, Yi-Ying; Yang, Yanyan; Wu, Wenjian; ... R01ES027255 Cell Mol Life Sci (2018 Dec) 30264181 Exiting the NIEHS site 2018 
Configurational and Conformational Equilibria of N6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3 ...   Bamberger, Stephanie N; Malik, Chanchal K; Voehler, Markus W; Brown, Summer K; Pan, Hope; Johns ... R01ES029357, T32ES007028 Chem Res Toxicol (2018 09 17) 30169026 Exiting the NIEHS site 2018 
Corrigendum: 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce muta ...   Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... R01ES025987 Nucleic Acids Res (2018 10 12) 30184121 Exiting the NIEHS site 2018 
Cytotoxic and mutagenic properties of alkyl phosphotriester lesions in Escherichia coli cells.   Wu, Jiabin; Wang, Pengcheng; Wang, Yinsheng R01ES025121 Nucleic Acids Res (2018 05 04) 29514270 Exiting the NIEHS site 2018 
Cytotoxic and mutagenic properties of minor-groove O2-alkylthymidine lesions in human cells.   Wu, Jun; Wang, Pengcheng; Li, Lin; You, Changjun; Wang, Yinsheng R01ES025121 J Biol Chem (2018 06 01) 29685891 Exiting the NIEHS site 2018 
Cytotoxic and mutagenic properties of O6-alkyl-2'-deoxyguanosine lesions in Escherichia coli cells.   Wang, Pengcheng; Wang, Yinsheng R01ES025121 J Biol Chem (2018 09 28) 30068548 Exiting the NIEHS site 2018 
Determination of thiocyanate in exhaled breath condensate.   Chandler, Joshua D; Horati, Hamed; Walker, Douglas I; Pagliano, Enea; Tirouvanziam, Rabindra; V ... P30ES019776, R01ES023485, U2CES026560 Free Radic Biol Med (2018 10) 30144632 Exiting the NIEHS site 2018 
Disulfiram combats cancer via crippling valosin-containing protein/p97 segregase adaptor NPL4.   Ding, Nan; Zhu, Qianzheng R01ES012991 Transl Cancer Res (2018 Apr) 30112292 Exiting the NIEHS site 2018 
DNA Damage, Mutagenesis and Cancer.   Basu, Ashis K R01ES023350 Int J Mol Sci (2018 Mar 23) 29570697 Exiting the NIEHS site 2018 
DNA polymerase beta participates in DNA End-joining.   Ray, Sreerupa; Breuer, Gregory; DeVeaux, Michelle; Zelterman, Daniel; Bindra, Ranjit; Sweasy, ... R01ES019179 Nucleic Acids Res (2018 01 09) 29161447 Exiting the NIEHS site 2018 
Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment R ...   Wen, Zhiwei; Peng, Jufang; Tuttle, Paloma R; Ren, Yaou; Garcia, Carol; Debnath, Dipra; Rishi, ... R01ES005775, R01ES023569 Org Lett (2018 12 07) 30457873 Exiting the NIEHS site 2018 
Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributio ...   Chakraborty, Sagnik; Steinbach, Peter J; Paul, Debamita; Mu, Hong; Broyde, Suse; Min, Jung-Hyu ... R01ES025987 Nucleic Acids Res (2018 02 16) 29267981 Exiting the NIEHS site 2018 
Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice (Mus ...   Deng, Yongfeng; Zhang, Yan; Qiao, Ruxia; Bonilla, Melvin M; Yang, Xiaoliang; Ren, Hongqiang; L ... R01ES027981 J Hazard Mater (2018 09 05) 29908513 Exiting the NIEHS site 2018 
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is dri ...   Hodel, Karl P; de Borja, Richard; Henninger, Erin E; Campbell, Brittany B; Ungerleider, Nathan; ... R01ES028271 Elife (2018 02 28) 29488881 Exiting the NIEHS site 2018 
Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae.   Barbari, Stephanie R; Kane, Daniel P; Moore, Elizabeth A; Shcherbakova, Polina V R01ES015869 G3 (Bethesda) (2018 03 02) 29352080 Exiting the NIEHS site 2018 
Genetic control of predominantly error-free replication through an acrolein-derived minor-groove DNA ...   Yoon, Jung-Hoon; Hodge, Richard P; Hackfeld, Linda C; Park, Jeseong; Roy Choudhury, Jayati; Pra ... R01ES022948 J Biol Chem (2018 02 23) 29330301 Exiting the NIEHS site 2018 
Genome-wide excision repair in Arabidopsis is coupled to transcription and reflects circadian gene e ...   Oztas, Onur; Selby, Christopher P; Sancar, Aziz; Adebali, Ogun P30ES010126, R01ES027255 Nat Commun (2018 04 17) 29666379 Exiting the NIEHS site 2018 
Histone tails decrease N7-methyl-2'-deoxyguanosine depurination and yield DNA-protein cross-links in ...   Yang, Kun; Park, Daeyoon; Tretyakova, Natalia Y; Greenberg, Marc M R01ES023350 Proc Natl Acad Sci U S A (2018 11 27) 30429328 Exiting the NIEHS site 2018 
Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and ...   Lu, Yuhong; Liu, Yanfeng; Oeck, Sebastian; Glazer, Peter M R01ES005775 Mol Cancer Res (2018 10) 29934325 Exiting the NIEHS site 2018 
Identification of ATIC as a Novel Target for Chemoradiosensitization.   Liu, Xiangfei; Paila, Uma Devi; Teraoka, Sharon N; Wright, Jocyndra A; Huang, Xin; Quinlan, Aa ... R01ES027121 Int J Radiat Oncol Biol Phys (2018 01 01) 29029884 Exiting the NIEHS site 2018 
Identification of YTH Domain-Containing Proteins as the Readers for N1-Methyladenosine in RNA.   Dai, Xiaoxia; Wang, Tianlu; Gonzalez, Gwendolyn; Wang, Yinsheng R01ES025121, T32ES018827 Anal Chem (2018 06 05) 29791134 Exiting the NIEHS site 2018 
Impact of tobacco-specific nitrosamine-derived DNA adducts on the efficiency and fidelity of DNA rep ...   Du, Hua; Leng, Jiapeng; Wang, Pengcheng; Li, Lin; Wang, Yinsheng R01ES025121 J Biol Chem (2018 07 13) 29789427 Exiting the NIEHS site 2018 
Importance of homo-dimerization of Fanconi-associated nuclease 1 in DNA flap cleavage.   Rao, Timsi; Longerich, Simonne; Zhao, Weixing; Aihara, Hideki; Sung, Patrick; Xiong, Yong R01ES007061 DNA Repair (Amst) (2018 04) 29518739 Exiting the NIEHS site 2018 
In a Class of Its Own: A New Family of Deubiquitinases Promotes Genome Stability.   Coleman, Kate E; Huang, Tony T R01ES025166 Mol Cell (2018 04 05) 29625031 Exiting the NIEHS site 2018 
Incomplete base excision repair contributes to cell death from antibiotics and other stresses.   Gruber, Charley C; Walker, Graham C R35ES028303 DNA Repair (Amst) (2018 11) 30181041 Exiting the NIEHS site 2018 
Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication b ...   Koag, Myong-Chul; Lee, Seongmin R01ES026676 Biochem J (2018 02 09) 29301983 Exiting the NIEHS site 2018 
Introduction to the Thematic Minireview Series: DNA double-strand break repair and pathway choice.   Sung, Patrick R01ES007061 J Biol Chem (2018 07 06) 29853635 Exiting the NIEHS site 2018 
Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination ...   Sulkowski, Parker L; Sundaram, Ranjini K; Oeck, Sebastian; Corso, Christopher D; Liu, Yanfeng; ... R01ES005775 Nat Genet (2018 08) 30013182 Exiting the NIEHS site 2018 
Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide ...   Mu, Hong; Zhang, Yingkai; Geacintov, Nicholas E; Broyde, Suse R01ES025987 Chem Res Toxicol (2018 11 19) 30284444 Exiting the NIEHS site 2018 
Long repeating (TTAGGG) n single-stranded DNA self-condenses i ...   Kar, Anirban; Jones, Nathan; Arat, N Özlem; Fishel, Richard; Griffith, Jack D R56ES013773 J Biol Chem (2018 06 15) 29674319 Exiting the NIEHS site 2018 
Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient c ...   Clements, Kristen E; Thakar, Tanay; Nicolae, Claudia M; Liang, Xinwen; Wang, Hong-Gang; Moldova ... R01ES026184 Nucleic Acids Res (2018 09 28) 30032296 Exiting the NIEHS site 2018 
Mapping-free variant calling using haplotype reconstruction from k-mer frequencies.   Audano, Peter A; Ravishankar, Shashidhar; Vannberg, Fredrik O R01ES026243 Bioinformatics (2018 05 15) 29186321 Exiting the NIEHS site 2018 
Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase.   Crickard, J Brooks; Kaniecki, Kyle; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Proc Natl Acad Sci U S A (2018 10 23) 30301803 Exiting the NIEHS site 2018 
Mitochondrial network responses in oxidative physiology and disease.   Go, Young-Mi; Fernandes, Jolyn; Hu, Xin; Uppal, Karan; Jones, Dean P P30ES019776, R01ES023485 Free Radic Biol Med (2018 02 20) 29317273 Exiting the NIEHS site 2018 
Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excisi ...   Mu, Hong; Geacintov, Nicholas E; Broyde, Suse; Yeo, Jung-Eun; Schärer, Orlando D R01ES025987 DNA Repair (Amst) (2018 11) 30174301 Exiting the NIEHS site 2018 
Monoubiquitinated γ-H2AX: Abundant product and specific biomarker for non-apoptotic DNA double-stran ...   Luczak, Michal W; Zhitkovich, Anatoly R01ES008786, R01ES028072 Toxicol Appl Pharmacol (2018 09 15) 30006243 Exiting the NIEHS site 2018 
Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease.   Chandler, Joshua D; Margaroli, Camilla; Horati, Hamed; Kilgore, Matthew B; Veltman, Mieke; Liu, ... P30ES019776, R01ES023485 Eur Respir J (2018 10) 30190273 Exiting the NIEHS site 2018 
Normalized Retention Time for Targeted Analysis of the DNA Adductome.   Cui, Yuxiang; Wang, Pengcheng; Yu, Yang; Yuan, Jun; Wang, Yinsheng R01ES029749 Anal Chem (2018 12 18) 30500177 Exiting the NIEHS site 2018 
Nucleosome positions establish an extended mutation signature in melanoma.   Brown, Alexander J; Mao, Peng; Smerdon, Michael J; Wyrick, John J; Roberts, Steven A R01ES028698 PLoS Genet (2018 11) 30485262 Exiting the NIEHS site 2018 
Oxidative stress predicts cognitive decline with aging in healthy adults: an observational study.   Hajjar, Ihab; Hayek, Salim S; Goldstein, Felicia C; Martin, Greg; Jones, Dean P; Quyyumi, Arsh ... P30ES019776, R01ES023485 J Neuroinflammation (2018 Jan 16) 29338747 Exiting the NIEHS site 2018 
PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress.   Schleicher, Emily M; Galvan, Adri M; Imamura-Kawasawa, Yuka; Moldovan, George-Lucian; Nicolae, ... R01ES026184 Nucleic Acids Res (2018 09 28) 30032250 Exiting the NIEHS site 2018 
PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF.   Sulkowski, Parker L; Scanlon, Susan E; Oeck, Sebastian; Glazer, Peter M R01ES005775 Mol Cancer Res (2018 08) 29739874 Exiting the NIEHS site 2018 
Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells.   Fernandes, Jolyn; Chandler, Joshua D; Liu, Ken H; Uppal, Karan; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485 Food Chem Toxicol (2018 Jun) 29684492 Exiting the NIEHS site 2018 
Pyrimidine Nucleosides with a Reactive (β-Chlorovinyl)sulfone or (β-Keto)sulfone Group at the C5 Pos ...   Suzol, Sazzad H; Howlader, A Hasan; Wen, Zhiwei; Ren, Yaou; Laverde, Eduardo E; Garcia, Carol; ... R01ES023569 ACS Omega (2018 Apr 30) 29732453 Exiting the NIEHS site 2018 
Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: ...   Liu, Shu-Lin; Wang, Zhi-Gang; Hu, Yusi; Xin, Yao; Singaram, Indira; Gorai, Sukhamoy; Zhou, Xi ... R21ES028384 Mol Cell (2018 09 20) 30174291 Exiting the NIEHS site 2018 
Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival.   Springall, Luke; Hughes, Craig D; Simons, Michelle; Azinas, Stavros; Van Houten, Bennett; Kad, ... R01ES019566 Nucleic Acids Res (2018 02 16) 29240933 Exiting the NIEHS site 2018 
Redox Equivalents and Mitochondrial Bioenergetics.   Roede, James R; Go, Young-Mi; Jones, Dean P R01ES023485, T32ES012870 Methods Mol Biol (2018) 29851002 Exiting the NIEHS site 2018 
Regulation of Hed1 and Rad54 binding during maturation of the meiosis-specific presynaptic complex.   Crickard, J Brooks; Kaniecki, Kyle; Kwon, YoungHo; Sung, Patrick; Lisby, Michael; Greene, Eric ... R01ES007061 EMBO J (2018 04 03) 29444896 Exiting the NIEHS site 2018 
Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis comp ...   Rizzo, Alessandro A; Vassel, Faye-Marie; Chatterjee, Nimrat; D'Souza, Sanjay; Li, Yunfeng; Hao, ... P30ES002109, R35ES028303 Proc Natl Acad Sci U S A (2018 08 28) 30111544 Exiting the NIEHS site 2018 
RNA polymerase II is released from the DNA template during transcription-coupled repair in mammalian ...   Chiou, Yi-Ying; Hu, Jinchuan; Sancar, Aziz; Selby, Christopher P R01ES027255 J Biol Chem (2018 02 16) 29282293 Exiting the NIEHS site 2018 
Selenium at the redox interface of the genome, metabolome and exposome.   Fernandes, Jolyn; Hu, Xin; Ryan Smith, M; Go, Young-Mi; Jones, Dean P R01ES023485 Free Radic Biol Med (2018 11 01) 29883789 Exiting the NIEHS site 2018 
Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice.   Hu, Xin; Chandler, Joshua D; Orr, Michael L; Hao, Li; Liu, Ken; Uppal, Karan; Go, Young-Mi; J ... P30ES019776, R01ES023485 J Nutr (2018 05 01) 29982657 Exiting the NIEHS site 2018 
Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung.   Hu, Xin; Chandler, Joshua D; Fernandes, Jolyn; Orr, Michael L; Hao, Li; Uppal, Karan; Neujahr, ... P30ES019776, R01ES023485 Biochim Biophys Acta Gen Subj (2018 Apr 12) 29656123 Exiting the NIEHS site 2018 
Single-cell mutagenic responses and cell death revealed in real time.   Van Houten, Bennett; Kad, Neil M R01ES019566 Proc Natl Acad Sci U S A (2018 07 10) 29946022 Exiting the NIEHS site 2018 
Single-nucleotide resolution dynamic repair maps of UV damage in Saccharomyces cerevisiae genome.   Li, Wentao; Adebali, Ogun; Yang, Yanyan; Selby, Christopher P; Sancar, Aziz P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2018 04 10) 29581276 Exiting the NIEHS site 2018 
Site-specific cross-linking of proteins to DNA via a new bioorthogonal approach employing oxime liga ...   Pujari, Suresh S; Zhang, Yi; Ji, Shaofei; Distefano, Mark D; Tretyakova, Natalia Y R01ES023350 Chem Commun (Camb) (2018 Jun 14) 29851420 Exiting the NIEHS site 2018 
Smoking gun for a rare mutation mechanism.   Goodman, Myron F R35ES028343 Nature (2018 02 08) 29420502 Exiting the NIEHS site 2018 
Spontaneous self-segregation of Rad51 and Dmc1 DNA recombinases within mixed recombinase filaments.   Crickard, J Brooks; Kaniecki, Kyle; Kwon, YoungHo; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2018 03 16) 29382724 Exiting the NIEHS site 2018 
Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dyn ...   Daigh, Leighton H; Liu, Chad; Chung, Mingyu; Cimprich, Karlene A; Meyer, Tobias R01ES016486 Cell Syst (2018 07 25) 29909278 Exiting the NIEHS site 2018 
Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Rep ...   Kou, Yi; Koag, Myong-Chul; Lee, Seongmin R01ES026676 Biochemistry (2018 08 28) 29957995 Exiting the NIEHS site 2018 
Studying protein-DNA interactions using atomic force microscopy.   Beckwitt, Emily C; Kong, Muwen; Van Houten, Bennett R01ES019566 Semin Cell Dev Biol (2018 01) 28673677 Exiting the NIEHS site 2018 
Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity ...   Scanlon, Susan E; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M R01ES005775 Oncotarget (2018 Jan 12) 29435132 Exiting the NIEHS site 2018 
Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing D ...   Cai, Yuqin; Fu, Iwen; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse R01ES025987 DNA Repair (Amst) (2018 05) 29631253 Exiting the NIEHS site 2018 
The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase acti ...   Suisse, Annabelle; Békés, Miklós; Huang, Tony T; Treisman, Jessica E R01ES025166 Fly (Austin) (2018) 29355077 Exiting the NIEHS site 2018 
The deoxyribose phosphate lyase of DNA polymerase β suppresses a processive DNA synthesis to prevent ...   Lai, Yanhao; Weizmann, Yossi; Liu, Yuan R01ES023569 Nucleic Acids Res (2018 09 28) 30085293 Exiting the NIEHS site 2018 
The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.   Kim, Hoon; Lin, Qun; Glazer, Peter M; Yun, Zhong R01ES005775 Breast Cancer Res (2018 03 06) 29510720 Exiting the NIEHS site 2018 
Toxicological Antagonism among Welding Fume Metals: Inactivation of Soluble Cr(VI) by Iron.   Krawic, Casey; Zhitkovich, Anatoly R01ES008786, R01ES028072 Chem Res Toxicol (2018 11 19) 30362728 Exiting the NIEHS site 2018 
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery.   Tonzi, Peter; Yin, Yandong; Lee, Chelsea Wei Ting; Rothenberg, Eli; Huang, Tony T R01ES025166 Elife (2018 11 13) 30422114 Exiting the NIEHS site 2018 
Urinary DNA adductomics - A novel approach for exposomics.   Cooke, Marcus S; Hu, Chiung-Wen; Chang, Yuan-Jhe; Chao, Mu-Rong R15ES027196, R15ES027196 Environ Int (2018 12) 30392940 Exiting the NIEHS site 2018 
What is the potential of nanolock- and nanocross-nanopore technology in cancer diagnosis?   Gu, Li-Qun; Gates, Kent S; Wang, Michael X; Li, Guangfu R01ES021007 Expert Rev Mol Diagn (2018 02) 29171309 Exiting the NIEHS site 2018 
xMWAS: a data-driven integration and differential network analysis tool.   Uppal, Karan; Ma, Chunyu; Go, Young-Mi; Jones, Dean P; Wren, Jonathan P30ES019776, R01ES023485 Bioinformatics (2018 02 15) 29069296 Exiting the NIEHS site 2018 
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and indu ...   Sulkowski, Parker L; Corso, Christopher D; Robinson, Nathaniel D; Scanlon, Susan E; Purshouse, ... R01ES005775 Sci Transl Med (2017 02 01) 28148839 Exiting the NIEHS site 2017 
A novel role of the Dna2 translocase function in DNA break resection.   Miller, Adam S; Daley, James M; Pham, Nhung Tuyet; Niu, Hengyao; Xue, Xiaoyu; Ira, Grzegorz; S ... R01ES007061 Genes Dev (2017 03 01) 28336516 Exiting the NIEHS site 2017 
A parametric model to estimate the proportion from true null using a distribution for p-values.   Yu, Chang; Zelterman, Daniel R01ES005775 Comput Stat Data Anal (2017 Oct) 28827889 Exiting the NIEHS site 2017 
A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA ...   Yang, Zhiyu; Nejad, Maryam Imani; Varela, Jacqueline Gamboa; Price, Nathan E; Wang, Yinsheng; G ... R01ES021007, T32ES018827 DNA Repair (Amst) (2017 04) 28262582 Exiting the NIEHS site 2017 
Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2.   Malfatti, Matilde Clarissa; Balachander, Sathya; Antoniali, Giulia; Koh, Kyung Duk; Saint-Pierre ... R01ES026243 Nucleic Acids Res (2017 Nov 02) 28977421 Exiting the NIEHS site 2017 
Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy.   Gupta, Anisha; Quijano, Elias; Liu, Yanfeng; Bahal, Raman; Scanlon, Susan E; Song, Eric; Hsieh ... R01ES005775 Mol Ther Nucleic Acids (2017 Dec 15) 29246289 Exiting the NIEHS site 2017 
ATM, radiation, and the risk of second primary breast cancer.   Bernstein, Jonine L; WECARE Study Collaborative Group; Concannon, Patrick R01ES027121 Int J Radiat Biol (2017 10) 28627265 Exiting the NIEHS site 2017 
BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.   Zhao, Weixing; Steinfeld, Justin B; Liang, Fengshan; Chen, Xiaoyong; Maranon, David G; Jian Ma, ... R01ES007061 Nature (2017 10 19) 28976962 Exiting the NIEHS site 2017 
Brevetoxin-2, is a unique inhibitor of the C-terminal redox center of mammalian thioredoxin reductas ...   Chen, Wei; Tuladhar, Anupama; Rolle, Shantelle; Lai, Yanhao; Rodriguez Del Rey, Freddy; Zavala, ... R01ES023569 Toxicol Appl Pharmacol (2017 08 15) 28551108 Exiting the NIEHS site 2017 
Cadmium stimulates myofibroblast differentiation and mouse lung fibrosis.   Hu, Xin; Fernandes, Jolyn; Jones, Dean P; Go, Young-Mi R01ES023485 Toxicology (2017 05 15) 28341147 Exiting the NIEHS site 2017 
Cellular Repair of DNA-DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane.   Chesner, Lisa N; Degner, Amanda; Sangaraju, Dewakar; Yomtoubian, Shira; Wickramaratne, Susith; ... R01ES023350 Int J Mol Sci (2017 May 18) 28524082 Exiting the NIEHS site 2017 
Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts.   Pujari, Suresh S; Tretyakova, Natalia R01ES023350 Chem Res Toxicol (2017 01 17) 27959490 Exiting the NIEHS site 2017 
Comprehensive Analysis of Hypermutation in Human Cancer.   Campbell, Brittany B; Light, Nicholas; Fabrizio, David; Zatzman, Matthew; Fuligni, Fabio; de Bo ... R01ES028271 Cell (2017 Nov 16) 29056344 Exiting the NIEHS site 2017 
Controlling the Graphene-Bio Interface: Dispersions in Animal Sera for Enhanced Stability and Reduce ...   Pattammattel, Ajith; Pande, Paritosh; Kuttappan, Deepa; Puglia, Megan; Basu, Ashis K; Amalaradj ... R01ES023350 Langmuir (2017 12 12) 29144756 Exiting the NIEHS site 2017 
Copper-mediated DNA damage by the neurotransmitter dopamine and L-DOPA: A pro-oxidant mechanism.   Rehmani, Nida; Zafar, Atif; Arif, Hussain; Hadi, Sheikh Mumtaz; Wani, Altaf A R01ES012991 Toxicol In Vitro (2017 Apr) 28137434 Exiting the NIEHS site 2017 
Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange.   Xu, Jingfei; Zhao, Lingyun; Xu, Yuanyuan; Zhao, Weixing; Sung, Patrick; Wang, Hong-Wei R01ES007061 Nat Struct Mol Biol (2017 01) 27941862 Exiting the NIEHS site 2017 
Cytotoxic and Mutagenic Properties of C3'-Epimeric Lesions of 2'-Deoxyribonucleosides in Escherichia ...   Wang, Pengcheng; Amato, Nicholas J; Wang, Yinsheng R01ES025121, T32ES018827 Biochemistry (2017 07 25) 28650656 Exiting the NIEHS site 2017 
Detection of the Excised, Damage-containing Oligonucleotide Products of Nucleotide Excision Repair i ...   Song, Jimyeong; Kemp, Michael G; Choi, Jun-Hyuk R01ES027255 Photochem Photobiol (2017 01) 27634428 Exiting the NIEHS site 2017 
Dissociation of Rad51 Presynaptic Complexes and Heteroduplex DNA Joints by Tandem Assemblies of Srs2 ...   Kaniecki, Kyle; De Tullio, Luisina; Gibb, Bryan; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Cell Rep (2017 Dec 12) 29241544 Exiting the NIEHS site 2017 
DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy.   Nemec, Antonia A; Abriola, Laura; Merkel, Jane S; de Stanchina, Elisa; DeVeaux, Michelle; Zelte ... R01ES019179 Mol Cancer Res (2017 03) 28074003 Exiting the NIEHS site 2017 
DNA repair and systemic lupus erythematosus.   Meas, Rithy; Burak, Matthew J; Sweasy, Joann B R01ES019179 DNA Repair (Amst) (2017 08) 28623091 Exiting the NIEHS site 2017 
Dynamic maps of UV damage formation and repair for the human genome.   Hu, Jinchuan; Adebali, Ogun; Adar, Sheera; Sancar, Aziz P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2017 06 27) 28607063 Exiting the NIEHS site 2017 
Dynamics of p53: A Master Decider of Cell Fate.   Luo, Qingyin; Beaver, Jill M; Liu, Yuan; Zhang, Zunzhen R01ES023569 Genes (Basel) (2017 Feb 09) 28208785 Exiting the NIEHS site 2017 
Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP.   Daley, James M; Jimenez-Sainz, Judit; Wang, Weibin; Miller, Adam S; Xue, Xiaoyu; Nguyen, Kevin ... R01ES007061 Cell Rep (2017 Oct 10) 29020620 Exiting the NIEHS site 2017 
Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.   Choe, Katherine N; Moldovan, George-Lucian R01ES026184 Mol Cell (2017 Feb 02) 28157503 Exiting the NIEHS site 2017 
From the Cover: Manganese Stimulates Mitochondrial H2O2 Production in SH-SY5Y Human Neuroblastoma Ce ...   Fernandes, Jolyn; Hao, Li; Bijli, Kaiser M; Chandler, Joshua D; Orr, Michael; Hu, Xin; Jones, ... P30ES019776, R01ES023485 Toxicol Sci (2017 01) 27701121 Exiting the NIEHS site 2017 
Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase.   Adebali, Ogun; Chiou, Yi-Ying; Hu, Jinchuan; Sancar, Aziz; Selby, Christopher P R01ES027255 Proc Natl Acad Sci U S A (2017 03 14) 28167766 Exiting the NIEHS site 2017 
Human CRL4DDB2 ubiquitin ligase preferentially regulates post-repair chromatin restoration of H3K56A ...   Zhu, Qianzheng; Wei, Shengcai; Sharma, Nidhi; Wani, Gulzar; He, Jinshan; Wani, Altaf A R01ES012991 Oncotarget (2017 Nov 28) 29262658 Exiting the NIEHS site 2017 
Human DNA polymerase η accommodates RNA for strand extension.   Su, Yan; Egli, Martin; Guengerich, F Peter R01ES010546, R01ES026955 J Biol Chem (2017 11 03) 28972162 Exiting the NIEHS site 2017 
Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyrene.   Li, Wentao; Hu, Jinchuan; Adebali, Ogun; Adar, Sheera; Yang, Yanyan; Chiou, Yi-Ying; Sancar, ... P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2017 06 27) 28607059 Exiting the NIEHS site 2017 
Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex.   Ma, Chu Jian; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2017 07 14) 28551686 Exiting the NIEHS site 2017 
Interstrand cross-links arising from strand breaks at true abasic sites in duplex DNA.   Yang, Zhiyu; Price, Nathan E; Johnson, Kevin M; Wang, Yinsheng; Gates, Kent S R01ES021007, T32ES018827 Nucleic Acids Res (2017 Jun 20) 28531327 Exiting the NIEHS site 2017 
Liquid Chromatography-Tandem Mass Spectrometry for the Quantification of Tobacco-Specific Nitrosamin ...   Leng, Jiapeng; Wang, Yinsheng R01ES025121 Anal Chem (2017 09 05) 28749651 Exiting the NIEHS site 2017 
Mass Spectrometry Based Proteomics Study of Cisplatin-Induced DNA-Protein Cross-Linking in Human Fib ...   Ming, Xun; Groehler 4th, Arnold; Michaelson-Richie, Erin D; Villalta, Peter W; Campbell, Colin; ... R01ES023350 Chem Res Toxicol (2017 04 17) 28282121 Exiting the NIEHS site 2017 
Mass Spectrometry-Based Tools to Characterize DNA-Protein Cross-Linking by Bis-Electrophiles.   Groehler 4th, Arnold; Degner, Amanda; Tretyakova, Natalia Y R01ES023350 Basic Clin Pharmacol Toxicol (2017 Sep) 28032943 Exiting the NIEHS site 2017 
Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis.   Xu, Liang; Wang, Wei; Wu, Jiabin; Shin, Ji Hyun; Wang, Pengcheng; Unarta, Ilona Christy; Chong ... R01ES025121 Proc Natl Acad Sci U S A (2017 08 22) 28784758 Exiting the NIEHS site 2017 
Mfd Protein and Transcription-Repair Coupling in Escherichia coli.   Selby, Christopher P R01ES027255 Photochem Photobiol (2017 01) 27864884 Exiting the NIEHS site 2017 
Mfd translocase is necessary and sufficient for transcription-coupled repair in Escherichia coli.   Adebali, Ogun; Sancar, Aziz; Selby, Christopher P R01ES027255 J Biol Chem (2017 11 10) 28986449 Exiting the NIEHS site 2017 
miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung ca ...   Gu, Shiyan; Lai, Yanhao; Chen, Hongyu; Liu, Yuan; Zhang, Zunzhen R01ES023569 Sci Rep (2017 09 22) 28939896 Exiting the NIEHS site 2017 
Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q.   Ren, Yaou; Lai, Yanhao; Laverde, Eduardo E; Lei, Ruipeng; Rein, Hayley L; Liu, Yuan R01ES023569 PLoS One (2017) 28475635 Exiting the NIEHS site 2017 
Molecular cartography of mutational landscapes in melanomas.   Beckwitt, Emily C; Van Houten, Bennett R01ES019566 EMBO J (2017 10 02) 28931563 Exiting the NIEHS site 2017 
Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans.   Hu, Jinchuan; Selby, Christopher P; Adar, Sheera; Adebali, Ogun; Sancar, Aziz P30ES010126, R01ES027255 J Biol Chem (2017 09 22) 28798238 Exiting the NIEHS site 2017 
Mutagenicity of a Model DNA-Peptide Cross-Link in Human Cells: Roles of Translesion Synthesis DNA Po ...   Pande, Paritosh; Ji, Shaofei; Mukherjee, Shivam; Schärer, Orlando D; Tretyakova, Natalia Y; Bas ... R01ES023350 Chem Res Toxicol (2017 Feb 20) 27951635 Exiting the NIEHS site 2017 
Nanoarmoring: strategies for preparation of multi-catalytic enzyme polymer conjugates and enhancemen ...   Zore, Omkar V; Pande, Paritosh; Okifo, Oghenenyerovwo; Basu, Ashis K; Kasi, Rajeswari M; Kumar, ... R01ES023350 RSC Adv (2017) 29403641 Exiting the NIEHS site 2017 
Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorig ...   Scanlon, Susan E; Scanlon, Christine D; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M R01ES005775 Carcinogenesis (2017 06 01) 28472268 Exiting the NIEHS site 2017 
Nickel-induced HIF-1α promotes growth arrest and senescence in normal human cells but lacks toxic ef ...   Luczak, Michal W; Zhitkovich, Anatoly R01ES008786 Toxicol Appl Pharmacol (2017 09 15) 28552779 Exiting the NIEHS site 2017 
Nucleosome Histone Tail Conformation and Dynamics: Impacts of Lysine Acetylation and a Nearby Minor ...   Fu, Iwen; Cai, Yuqin; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse R01ES025987 Biochemistry (2017 04 11) 28304160 Exiting the NIEHS site 2017 
Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA D ...   Adkins, Nicholas L; Swygert, Sarah G; Kaur, Parminder; Niu, Hengyao; Grigoryev, Sergei A; Sung, ... P30ES025128, R01ES007061 J Biol Chem (2017 Mar 31) 28202543 Exiting the NIEHS site 2017 
Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a ...   Mu, Hong; Geacintov, Nicholas E; Min, Jung-Hyun; Zhang, Yingkai; Broyde, Suse R01ES025987 Chem Res Toxicol (2017 06 19) 28460163 Exiting the NIEHS site 2017 
Nucleotide Excision Repair: Finely Tuned Molecular Orchestra of Early Pre-incision Events.   Zhu, Qianzheng; Wani, Altaf A R01ES012991 Photochem Photobiol (2017 01) 27696486 Exiting the NIEHS site 2017 
Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polym ...   Mertz, T M; Baranovskiy, A G; Wang, J; Tahirov, T H; Shcherbakova, P V R01ES015869 Oncogene (2017 Aug) 28368425 Exiting the NIEHS site 2017 
Optical Control of DNA Helicase Function through Genetic Code Expansion.   Luo, Ji; Kong, Muwen; Liu, Lili; Samanta, Subhas; Van Houten, Bennett; Deiters, Alexander R01ES019566 Chembiochem (2017 03 02) 28120472 Exiting the NIEHS site 2017 
PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PA ...   Liu, Lili; Kong, Muwen; Gassman, Natalie R; Freudenthal, Bret D; Prasad, Rajendra; Zhen, Steph ... R01ES019566 Nucleic Acids Res (2017 Dec 15) 29121337 Exiting the NIEHS site 2017 
PARPi focus the spotlight on replication fork protection in cancer.   Schlacher, Katharina R01ES029680 Nat Cell Biol (2017 Oct 31) 29087384 Exiting the NIEHS site 2017 
Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles.   Wang, Weibin; Daley, James M; Kwon, Youngho; Krasner, Danielle S; Sung, Patrick R01ES007061 Genes Dev (2017 12 01) 29321177 Exiting the NIEHS site 2017 
POLB: A new role of DNA polymerase beta in mitochondrial base excision repair.   Kaufman, Brett A; Van Houten, Bennett R01ES019566, R33ES025606 DNA Repair (Amst) (2017 12) 29129598 Exiting the NIEHS site 2017 
PostExcision Events in Human Nucleotide Excision Repair.   Kemp, Michael G; Hu, Jinchuan R01ES027255 Photochem Photobiol (2017 01) 27645806 Exiting the NIEHS site 2017 
Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine mo ...   Chen, Chengzhi; Jiang, Xuejun; Gu, Shiyan; Lai, Yanhao; Liu, Yuan; Zhang, Zunzhen R01ES023569 Environ Toxicol (2017 Aug) 27774770 Exiting the NIEHS site 2017 
Rad4 recognition-at-a-distance: Physical basis of conformation-specific anomalous diffusion of DNA r ...   Kong, Muwen; Van Houten, Bennett R01ES019566 Prog Biophys Mol Biol (2017 08) 27939760 Exiting the NIEHS site 2017 
Redox dynamics of manganese as a mitochondrial life-death switch.   Smith, Matthew Ryan; Fernandes, Jolyn; Go, Young-Mi; Jones, Dean P R01ES023485 Biochem Biophys Res Commun (2017 01 15) 28212723 Exiting the NIEHS site 2017 
Redox theory of aging: implications for health and disease.   Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485 Clin Sci (Lond) (2017 Jul 15) 28667066 Exiting the NIEHS site 2017 
Removal of oxidatively generated DNA damage by overlapping repair pathways.   Shafirovich, Vladimir; Geacintov, Nicholas E R01ES027059 Free Radic Biol Med (2017 06) 27818219 Exiting the NIEHS site 2017 
Repair-Resistant DNA Lesions.   Geacintov, Nicholas E; Broyde, Suse R01ES025987 Chem Res Toxicol (2017 08 21) 28750166 Exiting the NIEHS site 2017 
Replication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human ce ...   Price, Nathan E; Li, Lin; Gates, Kent S; Wang, Yinsheng R01ES021007, T32ES018827 Nucleic Acids Res (2017 Jun 20) 28431012 Exiting the NIEHS site 2017 
Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for ...   Barbari, Stephanie R; Shcherbakova, Polina V R01ES015869 DNA Repair (Amst) (2017 08) 28687338 Exiting the NIEHS site 2017 
Reversible DNA-Protein Cross-Linking at Epigenetic DNA Marks.   Ji, Shaofei; Shao, Hongzhao; Han, Qiyuan; Seiler, Christopher L; Tretyakova, Natalia Y R01ES023350 Angew Chem Int Ed Engl (2017 11 06) 28898504 Exiting the NIEHS site 2017 
Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced ...   Buzovetsky, Olga; Kwon, Youngho; Pham, Nhung Tuyet; Kim, Claire; Ira, Grzegorz; Sung, Patrick; ... R01ES007061 Cell Rep (2017 Nov 14) 29141206 Exiting the NIEHS site 2017 
SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligas ...   Coleman, Kate E; Békés, Miklós; Chapman, Jessica R; Crist, Sarah B; Jones, Mathew Jk; Ueberheid ... R01ES025166 Elife (2017 05 05) 28475037 Exiting the NIEHS site 2017 
Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases.   Lee, Ja Yil; Steinfeld, Justin B; Qi, Zhi; Kwon, YoungHo; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2017 06 30) 28476890 Exiting the NIEHS site 2017 
Sequence-Specific Covalent Capture Coupled with High-Contrast Nanopore Detection of a Disease-Derive ...   Nejad, Maryam Imani; Shi, Ruicheng; Zhang, Xinyue; Gu, Li-Qun; Gates, Kent S R01ES021007 Chembiochem (2017 07 18) 28422400 Exiting the NIEHS site 2017 
Single-Molecule Methods for Nucleotide Excision Repair: Building a System to Watch Repair in Real Ti ...   Kong, Muwen; Beckwitt, Emily C; Springall, Luke; Kad, Neil M; Van Houten, Bennett R01ES019566 Methods Enzymol (2017) 28668122 Exiting the NIEHS site 2017 
The Cartography of UV-induced DNA Damage Formation and DNA Repair.   Hu, Jinchuan; Adar, Sheera R01ES027255 Photochem Photobiol (2017 01) 27861959 Exiting the NIEHS site 2017 
The essential kinase ATR: ensuring faithful duplication of a challenging genome.   Saldivar, Joshua C; Cortez, David; Cimprich, Karlene A R01ES016486 Nat Rev Mol Cell Biol (2017 10) 28811666 Exiting the NIEHS site 2017 
The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RN ...   Kolbanovskiy, Marina; Chowdhury, Moinuddin A; Nadkarni, Aditi; Broyde, Suse; Geacintov, Nichola ... R01ES025987, R01ES027059 Biochemistry (2017 06 20) 28514164 Exiting the NIEHS site 2017 
Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA ad ...   Yoon, Jung-Hoon; Roy Choudhury, Jayati; Park, Jeseong; Prakash, Satya; Prakash, Louise R01ES022948 J Biol Chem (2017 11 10) 28939775 Exiting the NIEHS site 2017 
Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.   Basu, Ashis K; Pande, Paritosh; Bose, Arindam R01ES021762, R01ES023350 Chem Res Toxicol (2017 01 17) 27760288 Exiting the NIEHS site 2017 
Ultrathin Graphene-Protein Supercapacitors for Miniaturized Bioelectronics.   Mosa, Islam M; Pattammattel, Ajith; Kadimisetty, Karteek; Pande, Paritosh; El-Kady, Maher F; Bi ... R01ES023350 Adv Energy Mater (2017 Sep 06) 29104523 Exiting the NIEHS site 2017 
UV radiation-induced SUMOylation of DDB2 regulates nucleotide excision repair.   Han, Chunhua; Zhao, Ran; Kroger, John; He, Jinshan; Wani, Gulzar; Wang, Qi-En; Wani, Altaf A R01ES012991 Carcinogenesis (2017 10 01) 28981631 Exiting the NIEHS site 2017 
UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestratio ...   He, Jinshan; Zhu, Qianzheng; Wani, Gulzar; Wani, Altaf A R01ES012991 Oncotarget (2017 Feb 14) 28036256 Exiting the NIEHS site 2017 
Variation in Extracellular Detoxification Is a Link to Different Carcinogenicity among Chromates in ...   Krawic, Casey; Luczak, Michal W; Zhitkovich, Anatoly R01ES008786 Chem Res Toxicol (2017 09 18) 28759204 Exiting the NIEHS site 2017 
xMSannotator: An R Package for Network-Based Annotation of High-Resolution Metabolomics Data.   Uppal, Karan; Walker, Douglas I; Jones, Dean P P30ES019776, R01ES023485 Anal Chem (2017 01 17) 27977166 Exiting the NIEHS site 2017 
Yale school of public health symposium on lifetime exposures and human health: the exposome; summary ...   Johnson, Caroline H; Athersuch, Toby J; Collman, Gwen W; Dhungana, Suraj; Grant, David F; Jones ... P30ES019776, R01ES023485, U2CES026560 Hum Genomics (2017 Dec 08) 29221465 Exiting the NIEHS site 2017 
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiol ...   Kochenova, Olga V; Bezalel-Buch, Rachel; Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... R01ES015869 Nucleic Acids Res (2017 02 17) 28180291 Exiting the NIEHS site 2017 
Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous ...   De Tullio, Luisina; Kaniecki, Kyle; Kwon, Youngho; Crickard, J Brooks; Sung, Patrick; Greene, ... R01ES007061 Cell Rep (2017 Oct 17) 29045827 Exiting the NIEHS site 2017 
A genetically targetable near-infrared photosensitizer.   He, Jianjun; Wang, Yi; Missinato, Maria A; Onuoha, Ezenwa; Perkins, Lydia A; Watkins, Simon C; ... R01ES019566 Nat Methods (2016 Mar) 26808669 Exiting the NIEHS site 2016 
A tale of two cities: A tribute to Aziz Sancar's Nobel Prize in Chemistry for his molecular characte ...   Van Houten, Bennett R01ES019566 DNA Repair (Amst) (2016 Jan) 26861185 Exiting the NIEHS site 2016 
AP endonuclease 1 prevents the extension of a T/G mismatch by DNA polymerase β to prevent mutations ...   Lai, Yanhao; Jiang, Zhongliang; Zhou, Jing; Osemota, Emmanuel; Liu, Yuan R01ES023569 DNA Repair (Amst) (2016 07) 27183823 Exiting the NIEHS site 2016 
ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not ...   Ray, Alo; Blevins, Chessica; Wani, Gulzar; Wani, Altaf A R01ES012991 PLoS One (2016) 27442013 Exiting the NIEHS site 2016 
Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Sy ...   Wickramaratne, Susith; Ji, Shaofei; Mukherjee, Shivam; Su, Yan; Pence, Matthew G; Lior-Hoffmann ... R01ES010546, R01ES023350, R01ES025987 J Biol Chem (2016 Nov 04) 27621316 Exiting the NIEHS site 2016 
Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution.   Hu, Jinchuan; Lieb, Jason D; Sancar, Aziz; Adar, Sheera P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2016 10 11) 27688757 Exiting the NIEHS site 2016 
Comparative Error-Free and Error-Prone Translesion Synthesis of N(2)-2'-Deoxyguanosine Adducts Forme ...   Bose, Arindam; Surugihalli, Chaitra; Pande, Paritosh; Champeil, Elise; Basu, Ashis K R01ES023350 Chem Res Toxicol (2016 05 16) 27082015 Exiting the NIEHS site 2016 
Computational Metabolomics: A Framework for the Million Metabolome.   Uppal, Karan; Walker, Douglas I; Liu, Ken; Li, Shuzhao; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485, T32ES012870, U2CES026560 Chem Res Toxicol (2016 12 19) 27629808 Exiting the NIEHS site 2016 
Covalent DNA-Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells.   Groehler 4th, Arnold; Villalta, Peter W; Campbell, Colin; Tretyakova, Natalia R01ES023350 Chem Res Toxicol (2016 Feb 15) 26692166 Exiting the NIEHS site 2016 
Crosstalk between MSH2-MSH3 and polβ promotes trinucleotide repeat expansion during base excision re ...   Lai, Yanhao; Budworth, Helen; Beaver, Jill M; Chan, Nelson L S; Zhang, Zunzhen; McMurray, Cynt ... R01ES023569 Nat Commun (2016 08 22) 27546332 Exiting the NIEHS site 2016 
Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics.   Walker, Douglas I; Mallon, Col Timothy M; Hopke, Philip K; Uppal, Karan; Go, Young-Mi; Rohrbeck ... P30ES019776, R01ES023485, T32ES012870 J Occup Environ Med (2016 08) 27501099 Exiting the NIEHS site 2016 
Different ATM Signaling in Response to Chromium(VI) Metabolism via Ascorbate and Nonascorbate Reduct ...   Luczak, Michal W; Green, Samantha E; Zhitkovich, Anatoly R01ES008786 Environ Health Perspect (2016 Jan) 25977998 Exiting the NIEHS site 2016 
Differential DNA lesion formation and repair in heterochromatin and euchromatin.   Han, Chunhua; Srivastava, Amit Kumar; Cui, Tiantian; Wang, Qi-En; Wani, Altaf A R01ES012991 Carcinogenesis (2016 Feb) 26717995 Exiting the NIEHS site 2016 
Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.   Hess, Gaelen T; Frésard, Laure; Han, Kyuho; Lee, Cameron H; Li, Amy; Cimprich, Karlene A; Mont ... R01ES016486 Nat Methods (2016 Dec) 27798611 Exiting the NIEHS site 2016 
DNA repair: Clamping down on copy errors.   Kad, Neil M; Van Houten, Bennett R01ES019566 Nature (2016 11 24) 27851733 Exiting the NIEHS site 2016 
Effective molarity in a nucleic acid-controlled reaction.   Catalano, Michael J; Price, Nathan E; Gates, Kent S R01ES021007 Bioorg Med Chem Lett (2016 06 01) 27117430 Exiting the NIEHS site 2016 
Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end ...   Chen, Xuefeng; Niu, Hengyao; Yu, Yang; Wang, Jingjing; Zhu, Shuangyi; Zhou, Jianjie; Papusha, ... R01ES007061 Nucleic Acids Res (2016 Apr 7) 26801641 Exiting the NIEHS site 2016 
Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer-Associ ...   Nemec, Antonia A; Bush, Korie B; Towle-Weicksel, Jamie B; Taylor, B Frazier; Schulz, Vincent; W ... R01ES019179 Mol Cancer Res (2016 11) 27621267 Exiting the NIEHS site 2016 
Evolution of Telomeres in Schizosaccharomyces pombe and Its Possible Relationship to the Diversifica ...   Sepsiova, Regina; Necasova, Ivona; Willcox, Smaranda; Prochazkova, Katarina; Gorilak, Peter; No ... R56ES013773 PLoS One (2016) 27101289 Exiting the NIEHS site 2016 
Exposure Memory and Lung Regeneration.   Go, Young-Mi; Jones, Dean P R01ES023485 Ann Am Thorac Soc (2016 12) 28005420 Exiting the NIEHS site 2016 
How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair Pathway.   Coleman, Kate E; Huang, Tony T R01ES025166 Front Genet (2016) 27148358 Exiting the NIEHS site 2016 
HUWE1 comes to the rescue at stalled replication forks.   Coleman, Kate E; Huang, Tony T R01ES025166 EMBO Rep (2016 06) 27146074 Exiting the NIEHS site 2016 
HUWE1 interacts with PCNA to alleviate replication stress.   Choe, Katherine N; Nicolae, Claudia M; Constantin, Daniel; Imamura Kawasawa, Yuka; Delgado-Diaz, ... R01ES026184 EMBO Rep (2016 06) 27146073 Exiting the NIEHS site 2016 
Hydrogen peroxide and central redox theory for aerobic life: A tribute to Helmut Sies: Scout, trailb ...   Jones, Dean P P30ES019776, R01ES023485, U2CES026560 Arch Biochem Biophys (2016 Apr 01) 27095208 Exiting the NIEHS site 2016 
In Vitro Lesion Bypass Studies of O(4)-Alkylthymidines with Human DNA Polymerase η.   Williams, Nicole L; Wang, Pengcheng; Wu, Jiabin; Wang, Yinsheng R01ES025121 Chem Res Toxicol (2016 Apr 18) 27002924 Exiting the NIEHS site 2016 
Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat d ...   Rao, Anuradha; Kosters, Astrid; Mells, Jamie E; Zhang, Wujuan; Setchell, Kenneth D R; Amanso, ... P30ES019776, R01ES023485 Sci Transl Med (2016 09 21) 27655848 Exiting the NIEHS site 2016 
Low-dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice.   Chandler, Joshua D; Wongtrakool, Cherry; Banton, Sophia A; Li, Shuzhao; Orr, Michael L; Barr, ... R01ES023485, T32ES012870 Physiol Rep (2016 Jul) 27401458 Exiting the NIEHS site 2016 
Mass Spectrometry-Based Quantitative Strategies for Assessing the Biological Consequences and Repair ...   You, Changjun; Wang, Yinsheng R01ES025121 Acc Chem Res (2016 Feb 16) 26758048 Exiting the NIEHS site 2016 
Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel.   Jones, Dean P; Walker, Douglas I; Uppal, Karan; Rohrbeck, Patricia; Mallon, Col Timothy M; Go, ... P30ES019776, R01ES023485, T32ES012870 J Occup Environ Med (2016 08) 27501098 Exiting the NIEHS site 2016 
Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influ ...   Chandler, Joshua D; Hu, Xin; Ko, Eun-Ju; Park, Soojin; Lee, Young-Tae; Orr, Michael; Fernandes ... R01ES023485 Am J Physiol Regul Integr Comp Physiol (2016 11 01) 27558316 Exiting the NIEHS site 2016 
Metabolomics and Mycobacterial Disease: Don't Forget the Bioinformatics.   Collins, Jeffrey M; Kempker, Russell R; Ziegler, Thomas R; Blumberg, Henry M; Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Ann Am Thorac Soc (2016 Jan) 26730872 Exiting the NIEHS site 2016 
miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expre ...   Czochor, Jennifer R; Sulkowski, Parker; Glazer, Peter M R01ES005775 Mol Cancer Res (2016 Apr) 26850462 Exiting the NIEHS site 2016 
Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis.   Sueblinvong, Viranuj; Mills, Stephen T; Neujahr, David C; Go, Young-Mi; Jones, Dean P; Guidot, ... R01ES023485 Alcohol Clin Exp Res (2016 09) 27436123 Exiting the NIEHS site 2016 
PARP10 deficiency manifests by severe developmental delay and DNA repair defect.   Shahrour, Maher Awni; Nicolae, Claudia M; Edvardson, Simon; Ashhab, Motee; Galvan, Adri M; Cons ... R01ES026184 Neurogenetics (2016 10) 27624574 Exiting the NIEHS site 2016 
Patterns of growth and tract formation during the early development of secondary lineages in the Dro ...   Lovick, Jennifer K; Kong, Angel; Omoto, Jaison J; Ngo, Kathy T; Younossi-Hartenstein, Amelia; H ... R01ES029357 Dev Neurobiol (2016 Apr) 26178322 Exiting the NIEHS site 2016 
Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat dele ...   Beaver, Jill M; Lai, Yanhao; Rolle, Shantell J; Liu, Yuan R01ES023569 DNA Repair (Amst) (2016 12) 27793507 Exiting the NIEHS site 2016 
Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex.   Liang, Fengshan; Longerich, Simonne; Miller, Adam S; Tang, Caroline; Buzovetsky, Olga; Xiong, ... R01ES007061 Cell Rep (2016 06 07) 27239033 Exiting the NIEHS site 2016 
Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Pap ...   Békés, Miklós; van der Heden van Noort, Gerbrand J; Ekkebus, Reggy; Ovaa, Huib; Huang, Tony T; ... R01ES025166 Mol Cell (2016 05 19) 27203180 Exiting the NIEHS site 2016 
Replicative Bypass of O2-Alkylthymidine Lesions in Vitro.   Williams, Nicole L; Wang, Pengcheng; Wang, Yinsheng R01ES025121 Chem Res Toxicol (2016 10 17) 27611246 Exiting the NIEHS site 2016 
Role of XPD in cellular functions: To TFIIH and beyond.   Houten, Bennett Van; Kuper, Jochen; Kisker, Caroline R01ES019566 DNA Repair (Amst) (2016 08) 27262611 Exiting the NIEHS site 2016 
Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions.   You, Changjun; Wang, Pengcheng; Nay, Stephanie L; Wang, Jianshuang; Dai, Xiaoxia; O'Connor, Ti ... R01ES025121, T32ES018827 ACS Chem Biol (2016 05 20) 26930515 Exiting the NIEHS site 2016 
Sequencing the exposome: A call to action.   Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Toxicol Rep (2016) 26722641 Exiting the NIEHS site 2016 
Simple, High-Yield Syntheses of DNA Duplexes Containing Interstrand DNA-DNA Cross-Links Between an N ...   Gamboa Varela, Jacqueline; Gates, Kent S R01ES021007 Curr Protoc Nucleic Acid Chem (2016 06 01) 27248783 Exiting the NIEHS site 2016 
Single-Molecule Imaging Reveals that Rad4 Employs a Dynamic DNA Damage Recognition Process.   Kong, Muwen; Liu, Lili; Chen, Xuejing; Driscoll, Katherine I; Mao, Peng; Böhm, Stefanie; Kad, ... R01ES019566 Mol Cell (2016 10 20) 27720644 Exiting the NIEHS site 2016 
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks.   Cassani, Corinne; Gobbini, Elisa; Wang, Weibin; Niu, Hengyao; Clerici, Michela; Sung, Patrick; ... R01ES007061 PLoS Biol (2016 Feb) 26901759 Exiting the NIEHS site 2016 
Translesion synthesis of O4-alkylthymidine lesions in human cells.   Wu, Jun; Li, Lin; Wang, Pengcheng; You, Changjun; Williams, Nicole L; Wang, Yinsheng R01ES025121 Nucleic Acids Res (2016 Nov 02) 27466394 Exiting the NIEHS site 2016 
Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome ...   He, Jinshan; Zhu, Qianzheng; Wani, Gulzar; Sharma, Nidhi; Wani, Altaf A R01ES012991 J Biol Chem (2016 Apr 01) 26826127 Exiting the NIEHS site 2016 
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiol ...   Kochenova, Olga V; Bezalel-Buch, Rachel; Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... R01ES015869 Nucleic Acids Res (2016 Nov 29) 27903904 Exiting the NIEHS site 2016 
A rolling circle replication mechanism produces multimeric lariats of mitochondrial DNA in Caenorhab ...   Lewis, Samantha C; Joers, Priit; Willcox, Smaranda; Griffith, Jack D; Jacobs, Howard T; Hyman, ... R56ES013773 PLoS Genet (2015 Feb) 25693201 Exiting the NIEHS site 2015 
A simple, high-yield synthesis of DNA duplexes containing a covalent, thermally cleavable interstran ...   Gamboa Varela, Jacqueline; Gates, Kent S R01ES021007 Angew Chem Int Ed Engl (2015 Jun 22) 25967397 Exiting the NIEHS site 2015 
Anticancer therapeutic potential of Mn porphyrin/ascorbate system.   Tovmasyan, Artak; Sampaio, Romulo S; Boss, Mary-Keara; Bueno-Janice, Jacqueline C; Bader, Bader ... R01ES023485 Free Radic Biol Med (2015 Dec) 26496207 Exiting the NIEHS site 2015 
AP endonuclease 1 prevents trinucleotide repeat expansion via a novel mechanism during base excision ...   Beaver, Jill M; Lai, Yanhao; Xu, Meng; Casin, Astrid H; Laverde, Eduardo E; Liu, Yuan R01ES023569 Nucleic Acids Res (2015 Jul 13) 25990721 Exiting the NIEHS site 2015 
Bypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base ...   Jiang, Zhongliang; Xu, Meng; Lai, Yanhao; Laverde, Eduardo E; Terzidis, Michael A; Masi, Annal ... R01ES023569 DNA Repair (Amst) (2015 Sep) 26123757 Exiting the NIEHS site 2015 
Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair.   Han, Chunhua; Wani, Gulzar; Zhao, Ran; Qian, Jiang; Sharma, Nidhi; He, Jinshan; Zhu, Qianzhen ... R01ES012991 Cell Cycle (2015) 25483071 Exiting the NIEHS site 2015 
Characterization of Interstrand DNA-DNA Cross-Links Derived from Abasic Sites Using Bacteriophage ϕ2 ...   Yang, Zhiyu; Price, Nathan E; Johnson, Kevin M; Gates, Kent S R01ES021007 Biochemistry (2015 Jul 14) 26103998 Exiting the NIEHS site 2015 
Characterization of Interstrand DNA-DNA Cross-Links Using the α-Hemolysin Protein Nanopore.   Zhang, Xinyue; Price, Nathan E; Fang, Xi; Yang, Zhiyu; Gu, Li-Qun; Gates, Kent S R01ES021007 ACS Nano (2015 Dec 22) 26563913 Exiting the NIEHS site 2015 
Chemical and structural characterization of interstrand cross-links formed between abasic sites and ...   Price, Nathan E; Catalano, Michael J; Liu, Shuo; Wang, Yinsheng; Gates, Kent S R01ES021007 Nucleic Acids Res (2015 Apr 20) 25779045 Exiting the NIEHS site 2015 
Chemical structure and properties of interstrand cross-links formed by reaction of guanine residues ...   Catalano, Michael J; Liu, Shuo; Andersen, Nisana; Yang, Zhiyu; Johnson, Kevin M; Price, Nathan ... R01ES021007 J Am Chem Soc (2015 Mar 25) 25710271 Exiting the NIEHS site 2015 
Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing i ...   Mertz, Tony M; Sharma, Sushma; Chabes, Andrei; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2015 May 12) 25827231 Exiting the NIEHS site 2015 
Cytotoxic and mutagenic properties of O4-alkylthymidine lesions in Escherichia coli cells.   Wang, Pengcheng; Amato, Nicholas J; Zhai, Qianqian; Wang, Yinsheng R01ES025121 Nucleic Acids Res (2015 Dec 15) 26400162 Exiting the NIEHS site 2015 
Damaged DNA-binding protein down-regulates epigenetic mark H3K56Ac through histone deacetylase 1 and ...   Zhu, Qianzheng; Battu, Aruna; Ray, Alo; Wani, Gulzar; Qian, Jiang; He, Jinshan; Wang, Qi-en; ... R01ES012991 Mutat Res (2015 Jun) 26255936 Exiting the NIEHS site 2015 
Directly interrogating single quantum dot labelled UvrA2 molecules on DNA tightropes using an optica ...   Simons, Michelle; Pollard, Mark R; Hughes, Craig D; Ward, Andrew D; Van Houten, Bennett; Towrie ... R01ES019566 Sci Rep (2015 Dec 22) 26691010 Exiting the NIEHS site 2015 
Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using A ...   Go, Young-Mi; Kim, Chan Woo; Walker, Douglas I; Kang, Dong Won; Kumar, Sandeep; Orr, Michael; ... R01ES023485 Am J Physiol Regul Integr Comp Physiol (2015 Jan 1) 25377480 Exiting the NIEHS site 2015 
DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylati ...   DeLoughery, Zachary; Luczak, Michal W; Ortega-Atienza, Sara; Zhitkovich, Anatoly R01ES008786 Toxicol Sci (2015 Jan) 25288669 Exiting the NIEHS site 2015 
DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone c ...   Kochenova, Olga V; Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V R01ES015869 PLoS Genet (2015 Mar) 25826305 Exiting the NIEHS site 2015 
DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome.   Slaats, Gisela G; Saldivar, Joshua C; Bacal, Julien; Zeman, Michelle K; Kile, Andrew C; Hynes, ... R01ES016486 J Clin Invest (2015 Sep) 26301811 Exiting the NIEHS site 2015 
DNA sequence alignment by microhomology sampling during homologous recombination.   Qi, Zhi; Redding, Sy; Lee, Ja Yil; Gibb, Bryan; Kwon, YoungHo; Niu, Hengyao; Gaines, William ... R01ES007061 Cell (2015 Feb 26) 25684365 Exiting the NIEHS site 2015 
DNA-Protein Cross-Links: Formation, Structural Identities, and Biological Outcomes.   Tretyakova, Natalia Y; Groehler 4th, Arnold; Ji, Shaofei R01ES023350 Acc Chem Res (2015 Jun 16) 26032357 Exiting the NIEHS site 2015 
Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA ...   Wickramaratne, Susith; Boldry, Emily J; Buehler, Charles; Wang, Yen-Chih; Distefano, Mark D; Tr ... R01ES023350 J Biol Chem (2015 Jan 9) 25391658 Exiting the NIEHS site 2015 
Functions and regulation of the multitasking FANCM family of DNA motor proteins.   Xue, Xiaoyu; Sung, Patrick; Zhao, Xiaolan R01ES007061 Genes Dev (2015 Sep 01) 26341555 Exiting the NIEHS site 2015 
Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of t ...   Lokanga, Rachel Adihe; Senejani, Alireza Ghodsi; Sweasy, Joann Balazs; Usdin, Karen R01ES019179 PLoS Genet (2015 Apr) 25886163 Exiting the NIEHS site 2015 
HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.   Kile, Andrew C; Chavez, Diana A; Bacal, Julien; Eldirany, Sherif; Korzhnev, Dmitry M; Bezsonova ... R01ES016486 Mol Cell (2015 Jun 18) 26051180 Exiting the NIEHS site 2015 
Kinetic gating mechanism of DNA damage recognition by Rad4/XPC.   Chen, Xuejing; Velmurugu, Yogambigai; Zheng, Guanqun; Park, Beomseok; Shim, Yoonjung; Kim, You ... R01ES019566 Nat Commun (2015 Jan 06) 25562780 Exiting the NIEHS site 2015 
LKB1 preserves genome integrity by stimulating BRCA1 expression.   Gupta, Romi; Liu, Alex Y; Glazer, Peter M; Wajapeyee, Narendra R01ES005775 Nucleic Acids Res (2015 Jan) 25488815 Exiting the NIEHS site 2015 
Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in M ...   Go, Young-Mi; Sutliff, Roy L; Chandler, Joshua D; Khalidur, Rahman; Kang, Bum-Yong; Anania, Fr ... P30ES019776, R01ES023485, T32ES012870 Toxicol Sci (2015 Oct) 26187450 Exiting the NIEHS site 2015 
Markov counting models for correlated binary responses.   Crawford, Forrest W; Zelterman, Daniel R01ES005775 Biostatistics (2015 Jul) 25792624 Exiting the NIEHS site 2015 
Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts.   Liu, Shuo; Wang, Yinsheng R01ES021007 Chem Soc Rev (2015 Nov 7) 26204249 Exiting the NIEHS site 2015 
Mechanism of action studies of lomaiviticin A and the monomeric lomaiviticin aglycon. Selective and ...   Colis, Laureen C; Hegan, Denise C; Kaneko, Miho; Glazer, Peter M; Herzon, Seth B R01ES005775 J Am Chem Soc (2015 May 6) 25849366 Exiting the NIEHS site 2015 
Metabolic Characterization of the Common Marmoset (Callithrix jacchus).   Go, Young-Mi; Liang, Yongliang; Uppal, Karan; Soltow, Quinlyn A; Promislow, Daniel E L; Wachtma ... P30ES019776, R01ES023485, T32ES012870 PLoS One (2015) 26581102 Exiting the NIEHS site 2015 
Metabolome-wide association study of phenylalanine in plasma of common marmosets.   Go, Young-Mi; Walker, Douglas I; Soltow, Quinlyn A; Uppal, Karan; Wachtman, Lynn M; Strobel, F ... P30ES019776, R01ES023485, T32ES012870 Amino Acids (2015 Mar) 25526869 Exiting the NIEHS site 2015 
Metabolome-Wide Association Study of Primary Open Angle Glaucoma.   Burgess, L Goodwin; Uppal, Karan; Walker, Douglas I; Roberson, Rachel M; Tran, ViLinh; Parks, ... P30ES019776, R01ES023485, T32ES012870 Invest Ophthalmol Vis Sci (2015 Jul) 26230767 Exiting the NIEHS site 2015 
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.   Cheng, Christopher J; Bahal, Raman; Babar, Imran A; Pincus, Zachary; Barrera, Francisco; Liu, ... R01ES005775 Nature (2015 Feb 5) 25409146 Exiting the NIEHS site 2015 
Mimicking Ribosomal Unfolding of RNA Pseudoknot in a Protein Channel.   Zhang, Xinyue; Xu, Xiaojun; Yang, Zhiyu; Burcke, Andrew J; Gates, Kent S; Chen, Shi-Jie; Gu, ... R01ES021007 J Am Chem Soc (2015 Dec 23) 26595106 Exiting the NIEHS site 2015 
Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase γ by Org ...   Ciesielski, Grzegorz L; Bermek, Oya; Rosado-Ruiz, Fernando A; Hovde, Stacy L; Neitzke, Orrin J; ... R56ES013773 J Biol Chem (2015 Nov 27) 26446790 Exiting the NIEHS site 2015 
Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment.   Scanlon, Susan E; Glazer, Peter M R01ES005775 DNA Repair (Amst) (2015 Aug) 25956861 Exiting the NIEHS site 2015 
Origin and development of neuropil glia of the Drosophila larval and adult brain: Two distinct glial ...   Omoto, Jaison Jiro; Yogi, Puja; Hartenstein, Volker R01ES029357 Dev Biol (2015 Aug 15) 25779704 Exiting the NIEHS site 2015 
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.   Zhao, Weixing; Vaithiyalingam, Sivaraja; San Filippo, Joseph; Maranon, David G; Jimenez-Sainz, ... R01ES007061, R56ES021454 Mol Cell (2015 Jul 16) 26145171 Exiting the NIEHS site 2015 
Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Ra ...   Gaines, William A; Godin, Stephen K; Kabbinavar, Faiz F; Rao, Timsi; VanDemark, Andrew P; Sung, ... R01ES007061 Nat Commun (2015) 26215801 Exiting the NIEHS site 2015 
Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically ...   You, Changjun; Wang, Yinsheng R01ES025121 Nat Protoc (2015 Sep) 26292071 Exiting the NIEHS site 2015 
Redox theory of aging.   Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Redox Biol (2015 Aug) 25863726 Exiting the NIEHS site 2015 
Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exp ...   Go, Young-Mi; Walker, Douglas I; Liang, Yongliang; Uppal, Karan; Soltow, Quinlyn A; Tran, ViLi ... P30ES019776, R01ES023485, T32ES012870 Toxicol Sci (2015 Dec) 26358001 Exiting the NIEHS site 2015 
Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutat ...   Chen, Chengzhi; Jiang, Xuejun; Lai, Yanhao; Liu, Yuan; Zhang, Zunzhen R01ES023569 Environ Mol Mutagen (2015 Apr) 25339131 Exiting the NIEHS site 2015 
Rev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not ...   Yoon, Jung-Hoon; Park, Jeseong; Conde, Juan; Wakamiya, Maki; Prakash, Louise; Prakash, Satya R01ES022948 Genes Dev (2015 Dec 15) 26680302 Exiting the NIEHS site 2015 
Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links.   Sawant, Akshada; Kothandapani, Anbarasi; Zhitkovich, Anatoly; Sobol, Robert W; Patrick, Steve M R01ES008786 DNA Repair (Amst) (2015 Nov) 26519826 Exiting the NIEHS site 2015 
Selective modulation of the functions of a conserved DNA motor by a histone fold complex.   Xue, Xiaoyu; Choi, Koyi; Bonner, Jaclyn N; Szakal, Barnabas; Chen, Yu-Hung; Papusha, Alma; Sar ... R01ES007061 Genes Dev (2015 May 15) 25956905 Exiting the NIEHS site 2015 
Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homol ...   Zhao, Weixing; Sung, Patrick R01ES007061 Nucleic Acids Res (2015 Apr 30) 25820426 Exiting the NIEHS site 2015 
Synthesis of DNA Oligodeoxynucleotides Containing Site-Specific 1,3-Butadiene-Deoxyadenosine Lesions ...   Wickramaratne, Susith; Seiler, Christopher L; Tretyakova, Natalia Y R01ES023350 Curr Protoc Nucleic Acid Chem (2015 Jun 03) 26344227 Exiting the NIEHS site 2015 
Synthetic viability genomic screening defines Sae2 function in DNA repair.   Puddu, Fabio; Oelschlaegel, Tobias; Guerini, Ilaria; Geisler, Nicola J; Niu, Hengyao; Herzog, ... R01ES007061 EMBO J (2015 Jun 03) 25899817 Exiting the NIEHS site 2015 
The cysteine proteome.   Go, Young-Mi; Chandler, Joshua D; Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Free Radic Biol Med (2015 Jul) 25843657 Exiting the NIEHS site 2015 
The Redox Code.   Jones, Dean P; Sies, Helmut P30ES019776, R01ES023485, T32ES012870 Antioxid Redox Signal (2015 Sep 20) 25891126 Exiting the NIEHS site 2015 
Tumor suppressor p53 stole the AKT in hypoxia.   Yun, Zhong; Glazer, Peter M R01ES005775 J Clin Invest (2015 Jun) 25961449 Exiting the NIEHS site 2015 
USP7 deubiquitinase promotes ubiquitin-dependent DNA damage signaling by stabilizing RNF168.   Zhu, Qianzheng; Sharma, Nidhi; He, Jinshan; Wani, Gulzar; Wani, Altaf A R01ES012991 Cell Cycle (2015) 25894431 Exiting the NIEHS site 2015 
USP7 modulates UV-induced PCNA monoubiquitination by regulating DNA polymerase eta stability.   Qian, J; Pentz, K; Zhu, Q; Wang, Q; He, J; Srivastava, A K; Wani, A A R01ES012991 Oncogene (2015 Sep 03) 25435364 Exiting the NIEHS site 2015 
A 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass ...   Xu, Meng; Lai, Yanhao; Jiang, Zhongliang; Terzidis, Michael A; Masi, Annalisa; Chatgilialoglu, ... R01ES023569 Nucleic Acids Res (2014 Dec 16) 25428354 Exiting the NIEHS site 2014 
A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotyp ...   Kane, Daniel P; Shcherbakova, Polina V R01ES015869 Cancer Res (2014 Apr 1) 24525744 Exiting the NIEHS site 2014 
Amplified single base-pair mismatch detection via aggregation of exonuclease-sheared gold nanopartic ...   Wu, Shuo; Liang, Pingping; Yu, Haixiang; Xu, Xiaowen; Liu, Yuan; Lou, Xinhui; Xiao, Yi R01ES023569 Anal Chem (2014 Apr 1) 24611947 Exiting the NIEHS site 2014 
Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms.   Potenski, Catherine J; Niu, Hengyao; Sung, Patrick; Klein, Hannah L R01ES007061 Nature (2014 Jul 10) 24896181 Exiting the NIEHS site 2014 
Base excision repair of chemotherapeutically-induced alkylated DNA damage predominantly causes contr ...   Lai, Yanhao; Beaver, Jill M; Lorente, Karla; Melo, Jonathan; Ramjagsingh, Shyama; Agoulnik, Ir ... R01ES023569 PLoS One (2014) 24691413 Exiting the NIEHS site 2014 
Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates ...   Xu, Meng; Lai, Yanhao; Torner, Justin; Zhang, Yanbin; Zhang, Zunzhen; Liu, Yuan R01ES023569 Nucleic Acids Res (2014 Apr) 24423876 Exiting the NIEHS site 2014 
Causes and consequences of replication stress.   Zeman, Michelle K; Cimprich, Karlene A R01ES016486 Nat Cell Biol (2014 Jan) 24366029 Exiting the NIEHS site 2014 
Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single- ...   Gibb, Bryan; Ye, Ling F; Gergoudis, Stephanie C; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; G ... R01ES007061 PLoS One (2014) 24498402 Exiting the NIEHS site 2014 
Covalent adduct formation between the antihypertensive drug hydralazine and abasic sites in double- ...   Melton, Douglas; Lewis, Calvin D; Price, Nathan E; Gates, Kent S R01ES021007 Chem Res Toxicol (2014 Dec 15) 25405892 Exiting the NIEHS site 2014 
Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level i ...   Go, Young-Mi; Son, Dong Ju; Park, Heonyong; Orr, Michael; Hao, Li; Takabe, Wakako; Kumar, San ... R01ES023485 PLoS One (2014) 25265386 Exiting the NIEHS site 2014 
DNA damage-binding complex recruits HDAC1 to repress Bcl-2 transcription in human ovarian cancer cel ...   Zhao, Ran; Han, Chunhua; Eisenhauer, Eric; Kroger, John; Zhao, Weiqiang; Yu, Jianhua; Selvendi ... R01ES012991 Mol Cancer Res (2014 Mar) 24249678 Exiting the NIEHS site 2014 
DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis.   Zeman, Michelle K; Lin, Jia-Ren; Freire, Raimundo; Cimprich, Karlene A R01ES016486 J Cell Biol (2014 Jul 21) 25023518 Exiting the NIEHS site 2014 
DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures.   Northam, Matthew R; Moore, Elizabeth A; Mertz, Tony M; Binz, Sara K; Stith, Carrie M; Stepchenk ... R01ES015869 Nucleic Acids Res (2014 Jan) 24049079 Exiting the NIEHS site 2014 
Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair ...   Liu, Yan; Gaines, William A; Callender, Tracy; Busygina, Valeria; Oke, Ashwini; Sung, Patrick; ... R01ES007061 PLoS Genet (2014 Jan) 24465215 Exiting the NIEHS site 2014 
Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.   Scanlon, Susan E; Glazer, Peter M R01ES005775 Mol Cancer Res (2014 Jul) 24688021 Exiting the NIEHS site 2014 
Interplay between DNA repair and inflammation, and the link to cancer.   Kidane, Dawit; Chae, Wook Jin; Czochor, Jennifer; Eckert, Kristin A; Glazer, Peter M; Bothwell, ... R01ES019179 Crit Rev Biochem Mol Biol (2014 Mar-Apr) 24410153 Exiting the NIEHS site 2014 
Interstrand DNA-DNA cross-link formation between adenine residues and abasic sites in duplex DNA.   Price, Nathan E; Johnson, Kevin M; Wang, Jin; Fekry, Mostafa I; Wang, Yinsheng; Gates, Kent S R01ES021007 J Am Chem Soc (2014 Mar 5) 24506784 Exiting the NIEHS site 2014 
Investigation of bacterial nucleotide excision repair using single-molecule techniques.   Van Houten, Bennett; Kad, Neil R01ES019566 DNA Repair (Amst) (2014 Aug) 24472181 Exiting the NIEHS site 2014 
Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.   Zhao, Weixing; Saro, Dorina; Hammel, Michal; Kwon, Youngho; Xu, Yuanyuan; Rambo, Robert P; Wil ... R01ES007061 Nucleic Acids Res (2014 Jan) 24150939 Exiting the NIEHS site 2014 
Mitochondrial metabolomics using high-resolution Fourier-transform mass spectrometry.   Go, Young-Mi; Uppal, Karan; Walker, Douglas I; Tran, ViLinh; Dury, Lauriane; Strobel, Frederic ... R01ES023485, T32ES012870 Methods Mol Biol (2014) 25270922 Exiting the NIEHS site 2014 
Monitoring Cr intermediates and reactive oxygen species with fluorescent probes during chromate redu ...   DeLoughery, Zachary; Luczak, Michal W; Zhitkovich, Anatoly R01ES008786 Chem Res Toxicol (2014 May 19) 24646070 Exiting the NIEHS site 2014 
Mutation of POLB causes lupus in mice.   Senejani, Alireza G; Liu, Yanfeng; Kidane, Dawit; Maher, Stephen E; Zeiss, Caroline J; Park, H ... R01ES019179 Cell Rep (2014 Jan 16) 24388753 Exiting the NIEHS site 2014 
Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment ...   Lan, Li; Nakajima, Satoshi; Wei, Leizhen; Sun, Luxi; Hsieh, Ching-Lung; Sobol, Robert W; Bruch ... R01ES019566 Nucleic Acids Res (2014 Feb) 24293652 Exiting the NIEHS site 2014 
Nucleotide excision repair in Trypanosoma brucei: specialization of transcription-coupled repair due ...   Machado, Carlos R; Vieira-da-Rocha, João P; Mendes, Isabela Cecilia; Rajão, Matheus A; Marcello, ... R01ES019566 Mol Microbiol (2014 May) 24661334 Exiting the NIEHS site 2014 
Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules.   Gibb, Bryan; Ye, Ling F; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; Greene, Eric C R01ES007061 Nat Struct Mol Biol (2014 Oct) 25195049 Exiting the NIEHS site 2014 
Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences.   Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K R01ES021762, R01ES023350 PLoS One (2014) 25226389 Exiting the NIEHS site 2014 
Restriction of replication fork regression activities by a conserved SMC complex.   Xue, Xiaoyu; Choi, Koyi; Bonner, Jaclyn; Chiba, Tamara; Kwon, Youngho; Xu, Yuanyuan; Sanchez, ... R01ES007061 Mol Cell (2014 Nov 6) 25439736 Exiting the NIEHS site 2014 
Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on t ...   Lu, Yuhong; Wajapeyee, Narendra; Turker, Mitchell S; Glazer, Peter M R01ES005775 Cell Rep (2014 Jul 24) 25043185 Exiting the NIEHS site 2014 
Single molecule approaches: watching DNA repair one molecule at a time. Preface.   Kad, Neil M; Van Houten, Bennett R01ES019566 DNA Repair (Amst) (2014 Aug) 25059729 Exiting the NIEHS site 2014 
Single molecule techniques in DNA repair: a primer.   Hughes, Craig D; Simons, Michelle; Mackenzie, Cassidy E; Van Houten, Bennett; Kad, Neil M R01ES019566 DNA Repair (Amst) (2014 Aug) 24819596 Exiting the NIEHS site 2014 
Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via ...   Ghodke, Harshad; Wang, Hong; Hsieh, Ching L; Woldemeskel, Selamawit; Watkins, Simon C; Rapić-Ot ... R01ES019566 Proc Natl Acad Sci U S A (2014 May 6) 24760829 Exiting the NIEHS site 2014 
Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the mi ...   Zhai, Qianqian; Wang, Pengcheng; Cai, Qian; Wang, Yinsheng R01ES025121 Nucleic Acids Res (2014) 25120272 Exiting the NIEHS site 2014 
The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.   Colis, Laureen C; Woo, Christina M; Hegan, Denise C; Li, Zhenwu; Glazer, Peter M; Herzon, Seth ... R01ES005775 Nat Chem (2014 Jun) 24848236 Exiting the NIEHS site 2014 
The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a re ...   Nemec, Antonia A; Murphy, Drew L; Donigan, Katherine A; Sweasy, Joann B R01ES019179 J Biol Chem (2014 May 16) 24668809 Exiting the NIEHS site 2014 
Toward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreduc ...   Johnson, Kevin M; Parsons, Zachary D; Barnes, Charles L; Gates, Kent S R01ES021007 J Org Chem (2014 Aug 15) 25029663 Exiting the NIEHS site 2014 
Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human R ...   You, Changjun; Wang, Pengcheng; Dai, Xiaoxia; Wang, Yinsheng R01ES025121 Nucleic Acids Res (2014 Dec 16) 25404131 Exiting the NIEHS site 2014 
Transcriptional pausing to scout ahead for DNA damage.   Van Houten, Bennett; Kisker, Caroline R01ES019566 Proc Natl Acad Sci U S A (2014 Mar 18) 24599593 Exiting the NIEHS site 2014 
Transcriptome-metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals ...   Roede, James R; Uppal, Karan; Park, Youngja; Tran, ViLinh; Jones, Dean P P30ES019776, R01ES023485 Toxicol Rep (2014) 27722094 Exiting the NIEHS site 2014 
Ubiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC prot ...   He, Jinshan; Zhu, Qianzheng; Wani, Gulzar; Sharma, Nidhi; Han, Chunhua; Qian, Jiang; Pentz, K ... R01ES012991 J Biol Chem (2014 Sep 26) 25118285 Exiting the NIEHS site 2014 
USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15.   Sharma, Nidhi; Zhu, Qianzheng; Wani, Gulzar; He, Jingshan; Wang, Qi-en; Wani, Altaf A R01ES012991 Cell Cycle (2014) 24196443 Exiting the NIEHS site 2014 
A general path for large-scale solubilization of cellular proteins: from membrane receptors to multi ...   Pullara, Filippo; Guerrero-Santoro, Jennifer; Calero, Monica; Zhang, Qiangmin; Peng, Ye; Spåhr, ... R01ES019566 Protein Expr Purif (2013 Feb) 23137940 Exiting the NIEHS site 2013 
A quantitative mass spectrometry-based approach for assessing the repair of 8-methoxypsoralen-induce ...   Liu, Shuo; Wang, Yinsheng R01ES021007 Anal Chem (2013 Jul 16) 23789926 Exiting the NIEHS site 2013 
A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in m ...   Kadyrova, Lyudmila Y; Mertz, Tony M; Zhang, Yu; Northam, Matthew R; Sheng, Ziwei; Lobachev, Ki ... R01ES015869 PLoS Genet (2013 Oct) 24204308 Exiting the NIEHS site 2013 
A role for the MRN complex in ATR activation via TOPBP1 recruitment.   Duursma, Anja M; Driscoll, Robert; Elias, Josh E; Cimprich, Karlene A R01ES016486 Mol Cell (2013 Apr 11) 23582259 Exiting the NIEHS site 2013 
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.   Couch, Frank B; Bansbach, Carol E; Driscoll, Robert; Luzwick, Jessica W; Glick, Gloria G; Bétou ... R01ES016486, T32ES007028 Genes Dev (2013 Jul 15) 23873943 Exiting the NIEHS site 2013 
Caspase-2 short isoform interacts with membrane-associated cytoskeleton proteins to inhibit apoptosi ...   Han, Chunhua; Zhao, Ran; Kroger, John; Qu, Meihua; Wani, Altaf A; Wang, Qi-En R01ES012991 PLoS One (2013) 23840868 Exiting the NIEHS site 2013 
Cellular roles of DNA polymerase beta.   Ray, Sreerupa; Menezes, Miriam Rose; Senejani, Alireza; Sweasy, Joann B R01ES019179 Yale J Biol Med (2013 Dec 13) 24348210 Exiting the NIEHS site 2013 
Chromium(VI) causes interstrand DNA cross-linking in vitro but shows no hypersensitivity in cross-li ...   Morse, Jessica L; Luczak, Michal W; Zhitkovich, Anatoly R01ES008786 Chem Res Toxicol (2013 Oct 21) 24059640 Exiting the NIEHS site 2013 
Cognitive function and breast cancer: promise and potential insights from functional brain imaging.   Reuter-Lorenz, Patricia A; Cimprich, Bernadine R01ES016486 Breast Cancer Res Treat (2013 Jan) 23053652 Exiting the NIEHS site 2013 
Functional attributes of the Saccharomyces cerevisiae meiotic recombinase Dmc1.   Busygina, Valeria; Gaines, William A; Xu, Yuanyuan; Kwon, Youngho; Williams, Gareth J; Lin, Sh ... R01ES007061 DNA Repair (Amst) (2013 Sep) 23769192 Exiting the NIEHS site 2013 
Hypoxia and DNA repair.   Glazer, Peter M; Hegan, Denise C; Lu, Yuhong; Czochor, Jennifer; Scanlon, Susan E R01ES005775 Yale J Biol Med (2013 Dec 13) 24348208 Exiting the NIEHS site 2013 
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopath ...   Choi, Hyo Jei Claudia; Lin, Jia-Ren; Vannier, Jean-Baptiste; Slaats, Gisela G; Kile, Andrew C; ... R01ES016486 Mol Cell (2013 Aug 22) 23973373 Exiting the NIEHS site 2013 
NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinas ...   Ray, Alo; Milum, Keisha; Battu, Aruna; Wani, Gulzar; Wani, Altaf A R01ES012991 DNA Repair (Amst) (2013 Apr 01) 23422745 Exiting the NIEHS site 2013 
Nucleosome dynamics regulates DNA processing.   Adkins, Nicholas L; Niu, Hengyao; Sung, Patrick; Peterson, Craig L R01ES007061 Nat Struct Mol Biol (2013 Jul) 23728291 Exiting the NIEHS site 2013 
On the formation and properties of interstrand DNA-DNA cross-links forged by reaction of an abasic s ...   Johnson, Kevin M; Price, Nathan E; Wang, Jin; Fekry, Mostafa I; Dutta, Sanjay; Seiner, Derrick ... R01ES021007 J Am Chem Soc (2013 Jan 23) 23215239 Exiting the NIEHS site 2013 
p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide e ...   Wang, Qi-En; Han, Chunhua; Zhao, Ran; Wani, Gulzar; Zhu, Qianzheng; Gong, Li; Battu, Aruna; R ... R01ES012991 Nucleic Acids Res (2013 Feb 01) 23275565 Exiting the NIEHS site 2013 
p53 activation by Ni(II) is a HIF-1α independent response causing caspases 9/3-mediated apoptosis in ...   Wong, Victor C; Morse, Jessica L; Zhitkovich, Anatoly P42ES013660, R01ES008786 Toxicol Appl Pharmacol (2013 Jun 15) 23566959 Exiting the NIEHS site 2013 
PHD domain from human SHPRH.   Machado, Luciana E F; Pustovalova, Yulia; Kile, Andrew C; Pozhidaeva, Alexandra; Cimprich, Karl ... R01ES016486 J Biomol NMR (2013 Aug) 23907177 Exiting the NIEHS site 2013 
Pif1 helicase and Polýý promote recombination-coupled DNA synthesis via bubble migration.   Wilson, Marenda A; Kwon, YoungHo; Xu, Yuanyuan; Chung, Woo-Hyun; Chi, Peter; Niu, Hengyao; May ... R01ES007061 Nature (2013 Oct 17) 24025768 Exiting the NIEHS site 2013 
Postembryonic lineages of the Drosophila brain: I. Development of the lineage-associated fiber tract ...   Lovick, Jennifer K; Ngo, Kathy T; Omoto, Jaison J; Wong, Darren C; Nguyen, Joseph D; Hartenstei ... R01ES029357 Dev Biol (2013 Dec 15) 23880429 Exiting the NIEHS site 2013 
Prokaryotic nucleotide excision repair.   Kisker, Caroline; Kuper, Jochen; Van Houten, Bennett R01ES019566 Cold Spring Harb Perspect Biol (2013 Mar) 23457260 Exiting the NIEHS site 2013 
Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightrop ...   Hughes, Craig D; Wang, Hong; Ghodke, Harshad; Simons, Michelle; Towheed, Atif; Peng, Ye; Van H ... R01ES019566 Nucleic Acids Res (2013 May) 23511970 Exiting the NIEHS site 2013 
Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleoti ...   Vaisman, Alexandra; McDonald, John P; Huston, Donald; Kuban, Wojciech; Liu, Lili; Van Houten, ... R01ES019566 PLoS Genet (2013 Nov) 24244177 Exiting the NIEHS site 2013 
Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair.   McKibbin, Paige L; Fleming, Aaron M; Towheed, Mohammad Atif; Van Houten, Bennett; Burrows, Cynt ... R01ES019566 J Am Chem Soc (2013 Sep 18) 23930966 Exiting the NIEHS site 2013 
RIF1 in DNA break repair pathway choice.   Daley, James M; Sung, Patrick R01ES007061 Mol Cell (2013 Mar 07) 23473603 Exiting the NIEHS site 2013 
Role of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), c ...   Luczak, Michal W; Zhitkovich, Anatoly P42ES013660, R01ES008786 Free Radic Biol Med (2013 Dec) 23792775 Exiting the NIEHS site 2013 
Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIýý ...   Xue, Xiaoyu; Raynard, Steven; Busygina, Valeria; Singh, Akhilesh K; Sung, Patrick R01ES007061 J Biol Chem (2013 May 17) 23543748 Exiting the NIEHS site 2013 
Roles of DNA helicases in the mediation and regulation of homologous recombination.   Daley, James M; Niu, Hengyao; Sung, Patrick R01ES007061 Adv Exp Med Biol (2013) 23161012 Exiting the NIEHS site 2013 
The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free ...   Godin, Stephen; Wier, Adam; Kabbinavar, Faiz; Bratton-Palmer, Dominique S; Ghodke, Harshad; Van ... R01ES019566 Nucleic Acids Res (2013 Apr) 23460207 Exiting the NIEHS site 2013 
Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in gl ...   Racoma, Ira O; Meisen, Walter Hans; Wang, Qi-En; Kaur, Balveen; Wani, Altaf A R01ES012991 PLoS One (2013) 24039814 Exiting the NIEHS site 2013 
Uptake, p53 pathway activation, and cytotoxic responses for Co(II) and Ni(II) in human lung cells: i ...   Green, Samantha E; Luczak, Michal W; Morse, Jessica L; DeLoughery, Zachary; Zhitkovich, Anatoly P42ES013660, R01ES008786 Toxicol Sci (2013 Dec) 24068677 Exiting the NIEHS site 2013 
A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision.   Chen, Jia-Yun; Lin, Jia-Ren; Cimprich, Karlene A; Meyer, Tobias R01ES016486 Mol Cell (2012 Jan 27) 22206868 Exiting the NIEHS site 2012 
Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatini ...   Yeh, Joanne I; Levine, Arthur S; Du, Shoucheng; Chinte, Unmesh; Ghodke, Harshad; Wang, Hong; S ... R01ES019566 Proc Natl Acad Sci U S A (2012 Oct 9) 22822215 Exiting the NIEHS site 2012 
Dynamics of lesion processing by bacterial nucleotide excision repair proteins.   Kad, Neil M; Van Houten, Bennett R01ES019566 Prog Mol Biol Transl Sci (2012) 22749140 Exiting the NIEHS site 2012 
Finally, polyubiquitinated PCNA gets recognized.   Zeman, Michelle K; Cimprich, Karlene A R01ES016486 Mol Cell (2012 Aug 10) 22883622 Exiting the NIEHS site 2012 
Lack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differe ...   Zhu, Qianzheng; Wani, Gulzar; Sharma, Nidhi; Wani, Altaf R01ES012991 DNA Repair (Amst) (2012 Dec 1) 23083890 Exiting the NIEHS site 2012 
Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair.   Dunlop, Myun Hwa; Dray, Eloïse; Zhao, Weixing; San Filippo, Joseph; Tsai, Miaw-Sheue; Leung, S ... R01ES007061 J Biol Chem (2012 Apr 06) 22375013 Exiting the NIEHS site 2012 
Metabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process.   Wong, Victor; Armknecht, Susan; Zhitkovich, Anatoly P42ES013660, R01ES008786 J Trace Elem Med Biol (2012 Jun) 22572042 Exiting the NIEHS site 2012 
Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiot ...   Busygina, Valeria; Saro, Dorina; Williams, Gareth; Leung, Wing-Kit; Say, Amanda F; Sehorn, Mic ... R01ES007061 J Biol Chem (2012 Jan 06) 22115747 Exiting the NIEHS site 2012 
Nucleotide excision repair factor XPC enhances DNA damage-induced apoptosis by downregulating the an ...   Wang, Qi-En; Han, Chunhua; Zhang, Bo; Sabapathy, Kanaga; Wani, Altaf A R01ES012991 Cancer Res (2012 Feb 01) 22174370 Exiting the NIEHS site 2012 
Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction.   Furda, Amy M; Marrangoni, Adele M; Lokshin, Anna; Van Houten, Bennett R01ES019566 DNA Repair (Amst) (2012 Aug 01) 22766155 Exiting the NIEHS site 2012 
Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes.   Choi, Serah; Srivas, Rohith; Fu, Katherine Y; Hood, Brian L; Dost, Banu; Gibson, Gregory A; Wa ... R01ES014811, R01ES019566 J Proteome Res (2012 Oct 05) 22909323 Exiting the NIEHS site 2012 
RAD51 protein ATP cap regulates nucleoprotein filament stability.   Amunugama, Ravindra; He, Yujiong; Willcox, Smaranda; Forties, Robert A; Shim, Kang-Sup; Bundsch ... R56ES013773 J Biol Chem (2012 Mar 16) 22275364 Exiting the NIEHS site 2012 
Role of DNA polymerases in repeat-mediated genome instability.   Shah, Kartik A; Shishkin, Alexander A; Voineagu, Irina; Pavlov, Youri I; Shcherbakova, Polina V ... R01ES015869 Cell Rep (2012 Nov 29) 23142667 Exiting the NIEHS site 2012 
S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediate ...   Wong, Victor Chun-Lam; Cash, Haley L; Morse, Jessica L; Lu, Shan; Zhitkovich, Anatoly R01ES008786 Cell Cycle (2012 Jul 01) 22722496 Exiting the NIEHS site 2012 
Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA p ...   Asagoshi, Kenjiro; Lehmann, Wade; Braithwaite, Elena K; Santana-Santos, Lucas; Prasad, Rajendra ... R01ES019566 Nucleic Acids Res (2012 Jan) 21917855 Exiting the NIEHS site 2012 
The E288K colon tumor variant of DNA polymerase ýý is a sequence specific mutator.   Murphy, Drew L; Donigan, Katherine A; Jaeger, Joachim; Sweasy, Joann B R01ES019179 Biochemistry (2012 Jul 3) 22650412 Exiting the NIEHS site 2012 
Undetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) ...   Reynolds, Mindy; Armknecht, Susan; Johnston, Tatiana; Zhitkovich, Anatoly P42ES013660, R01ES008786 Mutagenesis (2012 Jul) 22241526 Exiting the NIEHS site 2012 
XPB helicase regulates DNA incision by the Thermoplasma acidophilum endonuclease Bax1.   Roth, Heide M; Romer, Johannes; Grundler, Verena; Van Houten, Bennett; Kisker, Caroline; Tessme ... R01ES019566 DNA Repair (Amst) (2012 Mar 1) 22237014 Exiting the NIEHS site 2012 
Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair interm ...   Senejani, Alireza G; Dalal, Shibani; Liu, Yanfeng; Nottoli, Timothy P; McGrath, James M; Clairm ... R01ES019179 Proc Natl Acad Sci U S A (2012 Apr 24) 22493258 Exiting the NIEHS site 2012 
Activation of protein kinase Tel1 through recognition of protein-bound DNA ends.   Fukunaga, Kenzo; Kwon, Youngho; Sung, Patrick; Sugimoto, Katsunori R01ES007061 Mol Cell Biol (2011 May) 21402778 Exiting the NIEHS site 2011 
Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like fac ...   Chi, Peter; Kwon, YoungHo; Visnapuu, Mari-Liis; Lam, Isabel; Santa Maria, Sergio R; Zheng, Xiu ... R01ES007061 Nucleic Acids Res (2011 Aug) 21558173 Exiting the NIEHS site 2011 
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG ...   Tann, Anne W; Boldogh, Istvan; Meiss, Gregor; Qian, Wei; Van Houten, Bennett; Mitra, Sankar; S ... R01ES019566, T32ES007254 J Biol Chem (2011 Sep 16) 21768646 Exiting the NIEHS site 2011 
ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation.   Battu, Aruna; Ray, Alo; Wani, Altaf A R01ES012991 Nucleic Acids Res (2011 Oct) 21727091 Exiting the NIEHS site 2011 
Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylatio ...   Chen, Xuefeng; Niu, Hengyao; Chung, Woo-Hyun; Zhu, Zhu; Papusha, Alma; Shim, Eun Yong; Lee, S ... R01ES007061 Nat Struct Mol Biol (2011 Sep) 21841787 Exiting the NIEHS site 2011 
Chromium in drinking water: sources, metabolism, and cancer risks.   Zhitkovich, Anatoly P42ES013660, R01ES008786 Chem Res Toxicol (2011 Oct 17) 21766833 Exiting the NIEHS site 2011 
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair.   Simsek, Deniz; Furda, Amy; Gao, Yankun; Artus, Jérôme; Brunet, Erika; Hadjantonakis, Anna-Kate ... R01ES019566 Nature (2011 Mar 10) 21390132 Exiting the NIEHS site 2011 
Differential contributory roles of nucleotide excision and homologous recombination repair for enhan ...   Wang, Qi-En; Milum, Keisha; Han, Chunhua; Huang, Yi-Wen; Wani, Gulzar; Thomale, Jurgen; Wani, ... R01ES012991 Mol Cancer (2011) 21385444 Exiting the NIEHS site 2011 
Energy metabolism in human pluripotent stem cells and their differentiated counterparts.   Varum, Sandra; Rodrigues, Ana S; Moura, Michelle B; Momcilovic, Olga; Easley 4th, Charles A; Ra ... R01ES019566 PLoS One (2011) 21698063 Exiting the NIEHS site 2011 
Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter.   Lu, Yuhong; Chu, Adrian; Turker, Mitchell S; Glazer, Peter M R01ES005775 Mol Cell Biol (2011 Aug) 21670155 Exiting the NIEHS site 2011 
Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision r ...   Mazloum, Nayef; Stegman, Melanie A; Croteau, Deborah L; Van Houten, Bennett; Kwon, Nyoun Soo; L ... R01ES019566 Biochemistry (2011 Mar 1) 21235228 Exiting the NIEHS site 2011 
Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells.   Babar, Imran A; Czochor, Jennifer; Steinmetz, Allison; Weidhaas, Joanne B; Glazer, Peter M; Sla ... R01ES005775 Cancer Biol Ther (2011 Nov 15) 22027557 Exiting the NIEHS site 2011 
Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51 ...   Dray, Eloïse; Dunlop, Myun Hwa; Kauppi, Liisa; San Filippo, Joseph; Wiese, Claudia; Tsai, Miaw ... R01ES007061 Proc Natl Acad Sci U S A (2011 Mar 01) 21307306 Exiting the NIEHS site 2011 
Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in ...   Kochenova, O V; Soshkina, J V; Stepchenkova, E I; Inge-Vechtomov, S G; Shcherbakova, P V R01ES015869 Biochemistry (Mosc) (2011 Jan) 21568839 Exiting the NIEHS site 2011 
Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts b ...   Liu, Yang; Reeves, Dara; Kropachev, Konstantin; Cai, Yuqin; Ding, Shuang; Kolbanovskiy, Marina ... R01ES019566 DNA Repair (Amst) (2011 Jul 15) 21741328 Exiting the NIEHS site 2011 
Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protei ...   Zheng, Xiao-Feng; Prakash, Rohit; Saro, Dorina; Longerich, Simonne; Niu, Hengyao; Sung, Patric ... R01ES007061 DNA Repair (Amst) (2011 Oct 10) 21880555 Exiting the NIEHS site 2011 
RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserve ...   Dunlop, Myun Hwa; Dray, Eloïse; Zhao, Weixing; Tsai, Miaw-Sheue; Wiese, Claudia; Schild, David ... R01ES007061 J Biol Chem (2011 Oct 28) 21903585 Exiting the NIEHS site 2011 
SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repa ...   Lin, Jia-Ren; Zeman, Michelle K; Chen, Jia-Yun; Yee, Muh-Ching; Cimprich, Karlene A R01ES016486 Mol Cell (2011 Apr 22) 21396873 Exiting the NIEHS site 2011 
Stem cell protein Piwil2 modulates chromatin modifications upon cisplatin treatment.   Wang, Qi-En; Han, Chunhua; Milum, Keisha; Wani, Altaf A R01ES012991 Mutat Res (2011 Mar 15) 21310163 Exiting the NIEHS site 2011 
The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell ...   Sharma, Neeru M; Kochenova, Olga V; Shcherbakova, Polina V R01ES015869 J Biol Chem (2011 Sep 23) 21799021 Exiting the NIEHS site 2011 
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions.   Hohl, Marcel; Kwon, Youngho; Galván, Sandra Muñoz; Xue, Xiaoyu; Tous, Cristina; Aguilera, Andr ... R01ES007061 Nat Struct Mol Biol (2011 Sep 04) 21892167 Exiting the NIEHS site 2011 
Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breas ...   Arafa, El-Shaimaa A; Zhu, Qianzheng; Shah, Zubair I; Wani, Gulzar; Barakat, Bassant M; Racoma, ... R01ES012991 Mutat Res (2011 Jan 10) 21040738 Exiting the NIEHS site 2011 
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in ...   Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2010 Jan 5) 19966286 Exiting the NIEHS site 2010 
Checkpoint recovery after DNA damage: a rolling stop for CDKs.   Duursma, Anja M; Cimprich, Karlene A R01ES016486 EMBO Rep (2010 Jun) 20467435 Exiting the NIEHS site 2010 
Continued primer synthesis at stalled replication forks contributes to checkpoint activation.   Van, Christopher; Yan, Shan; Michael, W Matthew; Waga, Shou; Cimprich, Karlene A R01ES016486 J Cell Biol (2010 Apr 19) 20385778 Exiting the NIEHS site 2010 
Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex.   Wang, Feng; Yang, Yuting; Singh, Thiyam Ramsing; Busygina, Valeria; Guo, Rong; Wan, Ke; Wang, ... R01ES007061 Structure (2010 Sep 08) 20826342 Exiting the NIEHS site 2010 
Dissociation of CAK from core TFIIH reveals a functional link between XP-G/CS and the TFIIH disassem ...   Arab, Hany H; Wani, Gulzar; Ray, Alo; Shah, Zubair I; Zhu, Qianzheng; Wani, Altaf A R01ES012991 PLoS One (2010) 20543986 Exiting the NIEHS site 2010 
DNA polymerases at the eukaryotic fork-20 years later.   Pavlov, Youri I; Shcherbakova, Polina V R01ES015869 Mutat Res (2010 Mar 01) 19682465 Exiting the NIEHS site 2010 
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.   Dray, Eloïse; Etchin, Julia; Wiese, Claudia; Saro, Dorina; Williams, Gareth J; Hammel, Michal; ... R01ES007061 Nat Struct Mol Biol (2010 Oct) 20871616 Exiting the NIEHS site 2010 
Histone modifications: crucial elements for damage response and chromatin restoration.   Zhu, Qianzheng; Wani, Altaf A R01ES012991 J Cell Physiol (2010 May) 20112283 Exiting the NIEHS site 2010 
Hsp27 protects adenocarcinoma cells from UV-induced apoptosis by Akt and p21-dependent pathways of s ...   Kanagasabai, Ragu; Karthikeyan, Krishnamurthy; Vedam, Kaushik; Qien, Wang; Zhu, Qianzheng; Ilan ... R01ES012991 Mol Cancer Res (2010 Oct) 20858736 Exiting the NIEHS site 2010 
Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2 ...   Hegan, Denise Campisi; Lu, Yuhong; Stachelek, Gregory C; Crosby, Meredith E; Bindra, Ranjit S; ... R01ES005775 Proc Natl Acad Sci U S A (2010 Feb 02) 20133863 Exiting the NIEHS site 2010 
Mechanism of DNA-protein cross-linking by chromium.   Macfie, Andrea; Hagan, Elizabeth; Zhitkovich, Anatoly P42ES013660, R01ES008786 Chem Res Toxicol (2010 Feb 15) 19877617 Exiting the NIEHS site 2010 
Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.   Niu, Hengyao; Chung, Woo-Hyun; Zhu, Zhu; Kwon, Youngho; Zhao, Weixing; Chi, Peter; Prakash, R ... R01ES007061 Nature (2010 Sep 2) 20811460 Exiting the NIEHS site 2010 
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via ...   Singh, Thiyam Ramsing; Saro, Dorina; Ali, Abdullah Mahmood; Zheng, Xiao-Feng; Du, Chang-hu; Kil ... R01ES007061 Mol Cell (2010 Mar 26) 20347429 Exiting the NIEHS site 2010 
Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmen ...   Barakat, Bassant M; Wang, Qi-En; Han, Chunhua; Milum, Keisha; Yin, De-Tao; Zhao, Qun; Wani, G ... R01ES012991 Int J Cancer (2010 Aug 15) 20013802 Exiting the NIEHS site 2010 
Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae.   Northam, Matthew R; Robinson, Heather A; Kochenova, Olga V; Shcherbakova, Polina V R01ES015869 Genetics (2010 Jan) 19841096 Exiting the NIEHS site 2010 
Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRC ...   Stachelek, Gregory C; Dalal, Shibani; Donigan, Katherine A; Campisi Hegan, Denise; Sweasy, Joan ... R01ES005775 Cancer Res (2010 Jan 01) 20028873 Exiting the NIEHS site 2010 
Promotion and regulation of homologous recombination by DNA helicases.   Colavito, Sierra; Prakash, Rohit; Sung, Patrick R01ES007061 Methods (2010 Jul) 20156560 Exiting the NIEHS site 2010 
Rad52 SUMOylation affects the efficiency of the DNA repair.   Altmannova, Veronika; Eckert-Boulet, Nadine; Arneric, Milica; Kolesar, Peter; Chaloupkova, Radk ... R01ES007061 Nucleic Acids Res (2010 Aug) 20371517 Exiting the NIEHS site 2010 
XPA impacts formation but not proteasome-sensitive repair of DNA-protein cross-links induced by chro ...   Zecevic, Alma; Hagan, Elizabeth; Reynolds, Mindy; Poage, Graham; Johnston, Tatiana; Zhitkovich, ... P42ES013660, R01ES008786 Mutagenesis (2010 Jul) 20410141 Exiting the NIEHS site 2010 
XRCC1 deficiency sensitizes human lung epithelial cells to genotoxicity by crocidolite asbestos and ...   Pietruska, Jodie R; Johnston, Tatiana; Zhitkovich, Anatoly; Kane, Agnes B P42ES013660, R01ES008786 Environ Health Perspect (2010 Dec) 20705543 Exiting the NIEHS site 2010 
A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stabi ...   Paulsen, Renee D; Soni, Deena V; Wollman, Roy; Hahn, Angela T; Yee, Muh-Ching; Guan, Anna; Hes ... R01ES016486 Mol Cell (2009 Jul 31) 19647519 Exiting the NIEHS site 2009 
Assay for human Rad51-mediated DNA displacement loop formation.   Raynard, Steven; Sung, Patrick R01ES007061 Cold Spring Harb Protoc (2009 Jan) 20147015 Exiting the NIEHS site 2009 
Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinat ...   Zhu, Qianzheng; Wani, Gulzar; Arab, Hany H; El-Mahdy, Mohamed A; Ray, Alo; Wani, Altaf A R01ES012991 DNA Repair (Amst) (2009 Feb 01) 19059499 Exiting the NIEHS site 2009 
Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermedia ...   Matulova, Petra; Marini, Victoria; Burgess, Rebecca C; Sisakova, Alexandra; Kwon, Youngho; Roth ... R01ES007061 J Biol Chem (2009 Mar 20) 19129197 Exiting the NIEHS site 2009 
DNA damage tolerance: when it's OK to make mistakes.   Chang, Debbie J; Cimprich, Karlene A R01ES016486 Nat Chem Biol (2009 Feb) 19148176 Exiting the NIEHS site 2009 
Emerging roles of microRNAs in the molecular responses to hypoxia.   Crosby, Meredith E; Devlin, Cecilia M; Glazer, Peter M; Calin, George A; Ivan, Mircea R01ES005775 Curr Pharm Des (2009) 19925433 Exiting the NIEHS site 2009 
Functional interactions of meiotic recombination factors Rdh54 and Dmc1.   Chi, Peter; Kwon, Youngho; Moses, Dana N; Seong, Changhyun; Sehorn, Michael G; Singh, Akhilesh ... R01ES007061 DNA Repair (Amst) (2009 Feb 1) 19028606 Exiting the NIEHS site 2009 
Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption.   Colavito, Sierra; Macris-Kiss, Margaret; Seong, Changhyun; Gleeson, Olive; Greene, Eric C; Klei ... R01ES007061 Nucleic Acids Res (2009 Nov) 19745052 Exiting the NIEHS site 2009 
HARPing on about the DNA damage response during replication.   Driscoll, Robert; Cimprich, Karlene A R01ES016486 Genes Dev (2009 Oct 15) 19833762 Exiting the NIEHS site 2009 
Human SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide ...   Ray, Alo; Mir, Safita N; Wani, Gulzar; Zhao, Qun; Battu, Aruna; Zhu, Qianzheng; Wang, Qi-En; ... R01ES012991 Mol Cell Biol (2009 Dec) 19805520 Exiting the NIEHS site 2009 
Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo.   Burgess, Rebecca C; Lisby, Michael; Altmannova, Veronika; Krejci, Lumir; Sung, Patrick; Rothste ... R01ES007061 J Cell Biol (2009 Jun 15) 19506039 Exiting the NIEHS site 2009 
MicroRNA regulation of DNA repair gene expression in hypoxic stress.   Crosby, Meredith E; Kulshreshtha, Ritu; Ivan, Mircea; Glazer, Peter M R01ES005775 Cancer Res (2009 Feb 01) 19141645 Exiting the NIEHS site 2009 
Modulation of nucleotide excision repair by mammalian SWI/SNF chromatin-remodeling complex.   Zhao, Qun; Wang, Qi-En; Ray, Alo; Wani, Gulzar; Han, Chunhua; Milum, Keisha; Wani, Altaf A R01ES012991 J Biol Chem (2009 Oct 30) 19740755 Exiting the NIEHS site 2009 
Proliferating cell nuclear antigen uses two distinct modes to move along DNA.   Kochaniak, Anna B; Habuchi, Satoshi; Loparo, Joseph J; Chang, Debbie J; Cimprich, Karlene A; Wa ... R01ES016486 J Biol Chem (2009 Jun 26) 19411704 Exiting the NIEHS site 2009 
Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers.   Reynolds, Mindy F; Peterson-Roth, Elizabeth C; Bespalov, Ivan A; Johnston, Tatiana; Gurel, Volk ... R01ES008786 Cancer Res (2009 Feb 01) 19141647 Exiting the NIEHS site 2009 
Regulation of Rad51 recombinase presynaptic filament assembly via interactions with the Rad52 mediat ...   Seong, Changhyun; Colavito, Sierra; Kwon, Youngho; Sung, Patrick; Krejci, Lumir R01ES007061 J Biol Chem (2009 Sep 04) 19605344 Exiting the NIEHS site 2009 
Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombinat ...   Shi, Idina; Hallwyl, Swee C L; Seong, Changhyun; Mortensen, Uffe; Rothstein, Rodney; Sung, Pat ... R01ES007061 J Biol Chem (2009 Nov 27) 19812039 Exiting the NIEHS site 2009 
Sem1p and Ubp6p orchestrate telomeric silencing by modulating histone H2B ubiquitination and H3 acet ...   Qin, Song; Wang, Qien; Ray, Alo; Wani, Gulzar; Zhao, Qun; Bhaumik, Sukesh R; Wani, Altaf A R01ES012991 Nucleic Acids Res (2009 Apr) 19188254 Exiting the NIEHS site 2009 
Structural transitions within human Rad51 nucleoprotein filaments.   Robertson, Ragan B; Moses, Dana N; Kwon, YoungHo; Chan, Pamela; Chi, Peter; Klein, Hannah; Sun ... R01ES007061 Proc Natl Acad Sci U S A (2009 Aug 4) 19622740 Exiting the NIEHS site 2009 
Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosp ...   Arafa, El-Shaimaa A; Zhu, Qianzheng; Barakat, Bassant M; Wani, Gulzar; Zhao, Qun; El-Mahdy, Mo ... R01ES012991 Cancer Res (2009 Dec 01) 19903849 Exiting the NIEHS site 2009 
Visualizing the disassembly of S. cerevisiae Rad51 nucleoprotein filaments.   Robertson, Ragan B; Moses, Dana N; Kwon, YoungHo; Chan, Pamela; Zhao, Weixing; Chi, Peter; Kle ... R01ES007061 J Mol Biol (2009 May 15) 19327367 Exiting the NIEHS site 2009 
WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chrom ...   Zecevic, Alma; Menard, Haley; Gurel, Volkan; Hagan, Elizabeth; DeCaro, Rosamaria; Zhitkovich, ... P42ES013660, R01ES008786, T32ES007272 Cell Cycle (2009 Sep 01) 19652551 Exiting the NIEHS site 2009 
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic re ...   Prakash, Rohit; Satory, Dominik; Dray, Eloïse; Papusha, Almas; Scheller, Jürgen; Kramer, Wilfr ... R01ES007061 Genes Dev (2009 Jan 01) 19136626 Exiting the NIEHS site 2009 
ATP-dependent chromatin remodeling by the Saccharomyces cerevisiae homologous recombination factor R ...   Kwon, YoungHo; Seong, Changhyun; Chi, Peter; Greene, Eric C; Klein, Hannah; Sung, Patrick R01ES007061 J Biol Chem (2008 Apr 18) 18292093 Exiting the NIEHS site 2008 
ATR: an essential regulator of genome integrity.   Cimprich, Karlene A; Cortez, David R01ES016486 Nat Rev Mol Cell Biol (2008 Aug) 18594563 Exiting the NIEHS site 2008 
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance a ...   Chan, Norman; Koritzinsky, Marianne; Zhao, Helen; Bindra, Ranjit; Glazer, Peter M; Powell, Sim ... R01ES005775 Cancer Res (2008 Jan 15) 18199558 Exiting the NIEHS site 2008 
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and ...   Salnikow, Konstantin; Zhitkovich, Anatoly P42ES013660, R01ES008786 Chem Res Toxicol (2008 Jan) 17970581 Exiting the NIEHS site 2008 
Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activity.   Plate, Iben; Hallwyl, Swee C L; Shi, Idina; Krejci, Lumir; Muller, Christian; Albertsen, Line; ... R01ES007061 J Biol Chem (2008 Oct 24) 18703507 Exiting the NIEHS site 2008 
Molecular anatomy of the recombination mediator function of Saccharomyces cerevisiae Rad52.   Seong, Changhyun; Sehorn, Michael G; Plate, Iben; Shi, Idina; Song, Binwei; Chi, Peter; Morten ... R01ES007061 J Biol Chem (2008 May 2) 18310075 Exiting the NIEHS site 2008 
Naringenin protects HaCaT human keratinocytes against UVB-induced apoptosis and enhances the removal ...   El-Mahdy, Mohamed A; Zhu, Qianzheng; Wang, Qi-En; Wani, Gulzar; Patnaik, Srinivas; Zhao, Qun; ... R01ES012991 Photochem Photobiol (2008 Mar-Apr) 18086244 Exiting the NIEHS site 2008 
Rad52 multimerization is important for its nuclear localization in Saccharomyces cerevisiae.   Plate, Iben; Albertsen, Line; Lisby, Michael; Hallwyl, Swee C L; Feng, Qi; Seong, Changhyun; R ... R01ES007061 DNA Repair (Amst) (2008 Jan 1) 17888746 Exiting the NIEHS site 2008 
Reduction with glutathione is a weakly mutagenic pathway in chromium(VI) metabolism.   Guttmann, David; Poage, Graham; Johnston, Tatiana; Zhitkovich, Anatoly P42ES013660, R01ES008786 Chem Res Toxicol (2008 Nov) 18808157 Exiting the NIEHS site 2008 
The chromate-inducible chrBACF operon from the transposable element TnOtChr confers resistance to ch ...   Branco, Rita; Chung, Ana Paula; Johnston, Tatiana; Gurel, Volkan; Morais, Paula; Zhitkovich, A ... P42ES013660, R01ES008786 J Bacteriol (2008 Nov) 18776016 Exiting the NIEHS site 2008 
The p38 mitogen-activated protein kinase augments nucleotide excision repair by mediating DDB2 degra ...   Zhao, Qun; Barakat, Bassant M; Qin, Song; Ray, Alo; El-Mahdy, Mohamed A; Wani, Gulzar; Arafa, ... R01ES012991 J Biol Chem (2008 Nov 21) 18806262 Exiting the NIEHS site 2008 
Analyzing the ATR-mediated checkpoint using Xenopus egg extracts.   Lupardus, Patrick J; Van, Christopher; Cimprich, Karlene A R01ES016486 Methods (2007 Feb) 17189864 Exiting the NIEHS site 2007 
Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA ...   Reynolds, Mindy; Stoddard, Lauren; Bespalov, Ivan; Zhitkovich, Anatoly R01ES008786, T32ES007272 Nucleic Acids Res (2007) 17169990 Exiting the NIEHS site 2007 
Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase.   Chi, Peter; San Filippo, Joseph; Sehorn, Michael G; Petukhova, Galina V; Sung, Patrick R01ES007061 Genes Dev (2007 Jul 15) 17639080 Exiting the NIEHS site 2007 
Cellular vitamin C increases chromate toxicity via a death program requiring mismatch repair but not ...   Reynolds, Mindy; Zhitkovich, Anatoly R01ES008786 Carcinogenesis (2007 Jul) 17301063 Exiting the NIEHS site 2007 
Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max net ...   Bindra, Ranjit S; Glazer, Peter M R01ES005775 Cancer Lett (2007 Jul 8) 17275176 Exiting the NIEHS site 2007 
Lessons from 50 years of SOS DNA-damage-induced mutagenesis.   Schlacher, Katharina; Goodman, Myron F R01ES029680 Nat Rev Mol Cell Biol (2007 07) 17551516 Exiting the NIEHS site 2007 
Probing ATR activation with model DNA templates.   Cimprich, Karlene A R01ES016486 Cell Cycle (2007 Oct 01) 17700074 Exiting the NIEHS site 2007 
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia.   Bindra, R S; Glazer, P M R01ES005775 Oncogene (2007 Mar 29) 17001309 Exiting the NIEHS site 2007 
Role of Claspin in regulation of nucleotide excision repair factor DDB2.   Praetorius-Ibba, Mette; Wang, Qi-En; Wani, Gulzar; El-Mahdy, Mohamed A; Zhu, Qianzheng; Qin, S ... R01ES012991 DNA Repair (Amst) (2007 May 01) 17196446 Exiting the NIEHS site 2007 
Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous ...   Zhang, Yu; Hefferin, Melissa L; Chen, Ling; Shim, Eun Yong; Tseng, Hui-Min; Kwon, Youngho; Sun ... R01ES007061 Nat Struct Mol Biol (2007 Jul) 17589524 Exiting the NIEHS site 2007 
The ATR pathway: fine-tuning the fork.   Paulsen, Renee D; Cimprich, Karlene A R01ES016486 DNA Repair (Amst) (2007 Jul 01) 17531546 Exiting the NIEHS site 2007 
The structural determinants of checkpoint activation.   MacDougall, Christina A; Byun, Tony S; Van, Christopher; Yee, Muh-ching; Cimprich, Karlene A R01ES016486 Genes Dev (2007 Apr 15) 17437996 Exiting the NIEHS site 2007 
The ubiquitin-proteasome system regulates p53-mediated transcription at p21waf1 promoter.   Zhu, Q; Wani, G; Yao, J; Patnaik, S; Wang, Q-E; El-Mahdy, M A; Praetorius-Ibba, M; Wani, A A R01ES012991 Oncogene (2007 Jun 21) 17224908 Exiting the NIEHS site 2007 
Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for effi ...   Wang, Qi-En; Praetorius-Ibba, Mette; Zhu, Qianzheng; El-Mahdy, Mohamed A; Wani, Gulzar; Zhao, ... R01ES012991 Nucleic Acids Res (2007) 17693435 Exiting the NIEHS site 2007 
Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel ...   Karaczyn, Aldona; Ivanov, Sergey; Reynolds, Mindy; Zhitkovich, Anatoly; Kasprzak, Kazimierz S; ... R01ES008786 J Cell Biochem (2006 Apr 1) 16288478 Exiting the NIEHS site 2006 
Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites.   Bindra, Ranjit S; Glazer, Peter M R01ES005775 Cancer Biol Ther (2006 Oct) 17106239 Exiting the NIEHS site 2006 
Causes of DNA single-strand breaks during reduction of chromate by glutathione in vitro and in cells ...   Messer, Joseph; Reynolds, Mindy; Stoddard, Lauren; Zhitkovich, Anatoly R01ES008786, T32ES007272 Free Radic Biol Med (2006 Jun 1) 16716899 Exiting the NIEHS site 2006 
CHK2-dependent phosphorylation of BRCA1 in hypoxia.   Gibson, Shannon L; Bindra, Ranjit S; Glazer, Peter M R01ES005775 Radiat Res (2006 Oct) 17007555 Exiting the NIEHS site 2006 
Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognit ...   El-Mahdy, Mohamed A; Zhu, Qianzheng; Wang, Qi-en; Wani, Gulzar; Praetorius-Ibba, Mette; Wani, ... R01ES012991 J Biol Chem (2006 May 12) 16527807 Exiting the NIEHS site 2006 
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, ...   Hegan, Denise Campisi; Narayanan, Latha; Jirik, Frank R; Edelmann, Winfried; Liskay, R Michael; ... R01ES005775 Carcinogenesis (2006 Dec) 16728433 Exiting the NIEHS site 2006 
DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DN ...   Li, Jinyou; Wang, Qi-En; Zhu, Qianzheng; El-Mahdy, Mohamed A; Wani, Gulzar; Praetorius-Ibba, M ... R01ES012991 Cancer Res (2006 Sep 01) 16951172 Exiting the NIEHS site 2006 
Lower mutagenicity but higher stability of Cr-DNA adducts formed during gradual chromate activation ...   Quievryn, George; Messer, Joseph; Zhitkovich, Anatoly P42ES013660, R01ES008786 Carcinogenesis (2006 Nov) 16714765 Exiting the NIEHS site 2006 
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires unc ...   Chang, Debbie J; Lupardus, Patrick J; Cimprich, Karlene A R01ES016486 J Biol Chem (2006 Oct 27) 16959771 Exiting the NIEHS site 2006 
Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage toler ...   Gibson, Shannon L; Narayanan, Latha; Hegan, Denise Campisi; Buermeyer, Andrew B; Liskay, R Mich ... R01ES005775 Cancer Lett (2006 Dec 8) 16426742 Exiting the NIEHS site 2006 
RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.   Schlacher, Katharina; Cox, Michael M; Woodgate, Roger; Goodman, Myron F R01ES029680 Nature (2006 Aug 24) 16929290 Exiting the NIEHS site 2006 
Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.   San Filippo, Joseph; Chi, Peter; Sehorn, Michael G; Etchin, Julia; Krejci, Lumir; Sung, Patric ... R01ES007061 J Biol Chem (2006 Apr 28) 16513631 Exiting the NIEHS site 2006 
Roles of ATP binding and ATP hydrolysis in human Rad51 recombinase function.   Chi, Peter; Van Komen, Stephen; Sehorn, Michael G; Sigurdsson, Stefan; Sung, Patrick R01ES007061 DNA Repair (Amst) (2006 Mar 7) 16388992 Exiting the NIEHS site 2006 
Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad ...   Chi, Peter; Kwon, Youngho; Seong, Changhyun; Epshtein, Anastasiya; Lam, Isabel; Sung, Patrick; ... R01ES007061 J Biol Chem (2006 Sep 8) 16831867 Exiting the NIEHS site 2006 
Cellular ubiquitination and proteasomal functions positively modulate mammalian nucleotide excision ...   Wang, Qi-En; Wani, Manzoor A; Chen, Jianming; Zhu, Qianzheng; Wani, Gulzar; El-Mahdy, Mohamed ... R01ES012991 Mol Carcinog (2005 Jan) 15547920 Exiting the NIEHS site 2005 
Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo.   Zhu, Qianzheng; Wani, Gulzar; Wang, Qi-en; El-mahdy, Mohamed; Snapka, Robert M; Wani, Altaf A R01ES012991 Exp Cell Res (2005 Jul 15) 15950624 Exiting the NIEHS site 2005 
DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation.   Wang, Qi-En; Zhu, Qianzheng; Wani, Gulzar; El-Mahdy, Mohamed A; Li, Jinyou; Wani, Altaf A R01ES012991 Nucleic Acids Res (2005) 16030353 Exiting the NIEHS site 2005 
Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair ...   Chen, Ling; Trujillo, Kelly M; Van Komen, Stephen; Roh, Dong Hyun; Krejci, Lumir; Lewis, L Kev ... R01ES007061 J Biol Chem (2005 Jan 28) 15546877 Exiting the NIEHS site 2005 
Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells.   Meng, Alice X; Jalali, Farid; Cuddihy, Andrew; Chan, Norman; Bindra, Ranjit S; Glazer, Peter M ... R01ES005775 Radiother Oncol (2005 Aug) 16026872 Exiting the NIEHS site 2005 
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.   Bindra, Ranjit S; Gibson, Shannon L; Meng, Alice; Westermark, Ulrica; Jasin, Maria; Pierce, An ... R01ES005775 Cancer Res (2005 Dec 15) 16357170 Exiting the NIEHS site 2005 
Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner.   Gibson, Shannon L; Bindra, Ranjit S; Glazer, Peter M R01ES005775 Cancer Res (2005 Dec 1) 16322218 Exiting the NIEHS site 2005 
Importance of chromium-DNA adducts in mutagenicity and toxicity of chromium(VI).   Zhitkovich, Anatoly R01ES008786 Chem Res Toxicol (2005 Jan) 15651842 Exiting the NIEHS site 2005 
Killing of chromium-damaged cells by mismatch repair and its relevance to carcinogenesis.   Zhitkovich, Anatoly; Peterson-Roth, Elizabeth; Reynolds, Mindy R01ES008786 Cell Cycle (2005 Aug) 15970712 Exiting the NIEHS site 2005 
Mismatch repair proteins are activators of toxic responses to chromium-DNA damage.   Peterson-Roth, Elizabeth; Reynolds, Mindy; Quievryn, George; Zhitkovich, Anatoly R01ES008786, T32ES007272 Mol Cell Biol (2005 May) 15831465 Exiting the NIEHS site 2005 
Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidanc ...   Prakash, Rohit; Krejci, Lumir; Van Komen, Stephen; Anke Schurer, Kirsten; Kramer, Wilfried; Sun ... R01ES007061 J Biol Chem (2005 Mar 4) 15634678 Exiting the NIEHS site 2005 
Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null ...   El-Mahdy, Mohamed A; Zhu, Qianzheng; Wang, Qi-En; Wani, Gulzar; Wani, Altaf A R01ES012991 Int J Cancer (2005 Nov 10) 15906362 Exiting the NIEHS site 2005 
Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced throug ...   Jensen, Ryan; Glazer, Peter M R01ES005775 Proc Natl Acad Sci U S A (2004 Apr 20) 15069205 Exiting the NIEHS site 2004 
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the ind ...   Salnikow, Konstantin; Donald, Steven P; Bruick, Richard K; Zhitkovich, Anatoly; Phang, James M; ... R01ES008786 J Biol Chem (2004 Sep 24) 15271983 Exiting the NIEHS site 2004 
Differential arrangements of conserved building blocks among homologs of the Rad50/Mre11 DNA repair ...   de Jager, Martijn; Trujillo, Kelly M; Sung, Patrick; Hopfner, Karl-Peter; Carney, James P; Tain ... R01ES007061 J Mol Biol (2004 Jun 11) 15165861 Exiting the NIEHS site 2004 
Differentiation of DNA reactive and non-reactive genotoxic mechanisms using gene expression profile ...   Dickinson, Donna A; Warnes, Gregory R; Quievryn, George; Messer, Joseph; Zhitkovich, Anatoly; R ... R01ES008786 Mutat Res (2004 May 18) 15120961 Exiting the NIEHS site 2004 
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells.   Bindra, Ranjit S; Schaffer, Paul J; Meng, Alice; Woo, Jennifer; Måseide, Kårstein; Roth, Matt ... R01ES005775 Mol Cell Biol (2004 Oct) 15367671 Exiting the NIEHS site 2004 
Human nucleotide excision repair efficiently removes chromium-DNA phosphate adducts and protects cel ...   Reynolds, Mindy; Peterson, Elizabeth; Quievryn, George; Zhitkovich, Anatoly R01ES008786, T32ES007272 J Biol Chem (2004 Jul 16) 15087443 Exiting the NIEHS site 2004 
Meiotic recombination: an affair of two recombinases.   Sehorn, Michael G; Sung, Patrick R01ES007061 Cell Cycle (2004 Nov) 15547324 Exiting the NIEHS site 2004 
Multiple interactions with the Rad51 recombinase govern the homologous recombination function of Rad ...   Raschle, Markus; Van Komen, Stephen; Chi, Peter; Ellenberger, Tom; Sung, Patrick R01ES007061 J Biol Chem (2004 Dec 10) 15465810 Exiting the NIEHS site 2004 
Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52.   Motycka, Teresa A; Bessho, Tadayoshi; Post, Sean M; Sung, Patrick; Tomkinson, Alan E R01ES007061 J Biol Chem (2004 Apr 2) 14734547 Exiting the NIEHS site 2004 
Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein.   Krejci, Lumir; Macris, Margaret; Li, Ying; Van Komen, Stephen; Villemain, Jana; Ellenberger, T ... R01ES007061 J Biol Chem (2004 May 28) 15047689 Exiting the NIEHS site 2004 
Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand break ...   Lewis, L Kevin; Storici, Francesca; Van Komen, Stephen; Calero, Shanna; Sung, Patrick; Resnick, ... R01ES007061 Genetics (2004 Apr) 15126391 Exiting the NIEHS site 2004 
UV radiation-induced XPC translocation within chromatin is mediated by damaged-DNA binding protein, ...   Wang, Qi-En; Zhu, Qianzheng; Wani, Gulzar; Chen, Jianming; Wani, Altaf A R01ES012991 Carcinogenesis (2004 Jun) 14742321 Exiting the NIEHS site 2004 
ATPase and DNA helicase activities of the Saccharomyces cerevisiae anti-recombinase Srs2.   Van Komen, Stephen; Reddy, Mothe Sreedhar; Krejci, Lumir; Klein, Hannah; Sung, Patrick R01ES007061 J Biol Chem (2003 Nov 7) 12966095 Exiting the NIEHS site 2003 
Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.   Mihaylova, Valia T; Bindra, Ranjit S; Yuan, Jianling; Campisi, Denise; Narayanan, Latha; Jensen ... R01ES005775 Mol Cell Biol (2003 May) 12697826 Exiting the NIEHS site 2003 
Elevated levels of DNA-protein crosslinks and micronuclei in peripheral lymphocytes of tannery worke ...   Medeiros, M G; Rodrigues, A S; Batoréu, M C; Laires, A; Rueff, J; Zhitkovich, A R01ES008786 Mutagenesis (2003 Jan) 12473731 Exiting the NIEHS site 2003 
Genetic control of interconnected neuronal populations in the mouse primary visual system.   Seecharan, Dave J; Kulkarni, Anand L; Lu, Lu; Rosen, Glenn D; Williams, Robert W R01ES012991 J Neurosci (2003 Dec 03) 14657177 Exiting the NIEHS site 2003 
Genotoxicity and mutagenicity of chromium(VI)/ascorbate-generated DNA adducts in human and bacterial ...   Quievryn, George; Peterson, Elizabeth; Messer, Joseph; Zhitkovich, Anatoly R01ES008786, T32ES007272 Biochemistry (2003 Feb 4) 12549927 Exiting the NIEHS site 2003 
Rad51 recombinase and recombination mediators.   Sung, Patrick; Krejci, Lumir; Van Komen, Stephen; Sehorn, Michael G R01ES007061 J Biol Chem (2003 Oct 31) 12912992 Exiting the NIEHS site 2003 
Yeast xrs2 binds DNA and helps target rad50 and mre11 to DNA ends.   Trujillo, Kelly M; Roh, Dong Hyun; Chen, Ling; Van Komen, Stephen; Tomkinson, Alan; Sung, Patr ... R01ES007061 J Biol Chem (2003 Dec 05) 14522986 Exiting the NIEHS site 2003 
Carcinogenic chromium(VI) induces cross-linking of vitamin C to DNA in vitro and in human lung A549 ...   Quievryn, George; Messer, Joseph; Zhitkovich, Anatoly R01ES008786 Biochemistry (2002 Mar 05) 11863455 Exiting the NIEHS site 2002 
Functional cross-talk among Rad51, Rad54, and replication protein A in heteroduplex DNA joint format ...   Van Komen, Stephen; Petukhova, Galina; Sigurdsson, Stefan; Sung, Patrick R01ES007061 J Biol Chem (2002 Nov 15) 12226081 Exiting the NIEHS site 2002 
Interaction with Rad51 is indispensable for recombination mediator function of Rad52.   Krejci, Lumir; Song, Binwei; Bussen, Wendy; Rothstein, Rodney; Mortensen, Uffe H; Sung, Patric ... R01ES007061 J Biol Chem (2002 Oct 18) 12171935 Exiting the NIEHS site 2002 
Reductive activation with cysteine represents a chromium(III)-dependent pathway in the induction of ...   Zhitkovich, Anatoly; Quievryn, George; Messer, Joseph; Motylevich, Zhanna R01ES008786 Environ Health Perspect (2002 Oct) 12426121 Exiting the NIEHS site 2002 
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiat ...   Peretz, S; Jensen, R; Baserga, R; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (2001 Feb 13) 11172010 Exiting the NIEHS site 2001 
Basis for avid homologous DNA strand exchange by human Rad51 and RPA.   Sigurdsson, S; Trujillo, K; Song, B; Stratton, S; Sung, P R01ES007061 J Biol Chem (2001 Mar 23) 11124265 Exiting the NIEHS site 2001 
DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hy ...   Rice, K P; Eggler, A L; Sung, P; Cox, M M R01ES007061 J Biol Chem (2001 Oct 19) 11504729 Exiting the NIEHS site 2001 
DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex.   Trujillo, K M; Sung, P R01ES007061 J Biol Chem (2001 Sep 21) 11454871 Exiting the NIEHS site 2001 
Hypermutability to ionizing radiation in mismatch repair-deficient, Pms2 knockout mice.   Xu, X S; Narayanan, L; Dunklee, B; Liskay, R M; Glazer, P M R01ES005775 Cancer Res (2001 May 1) 11325851 Exiting the NIEHS site 2001 
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange.   Sigurdsson, S; Van Komen, S; Bussen, W; Schild, D; Albala, J S; Sung, P R01ES007061 Genes Dev (2001 Dec 15) 11751636 Exiting the NIEHS site 2001 
Non-oxidative mechanisms are responsible for the induction of mutagenesis by reduction of Cr(VI) wit ...   Zhitkovich, A; Song, Y; Quievryn, G; Voitkun, V R01ES008786 Biochemistry (2001 Jan 16) 11148050 Exiting the NIEHS site 2001 
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes.   Chen, L; Trujillo, K; Ramos, W; Sung, P; Tomkinson, A E R01ES007061 Mol Cell (2001 Nov) 11741545 Exiting the NIEHS site 2001 
Reduction of Cr (VI) by cysteine: significance in human lymphocytes and formation of DNA damage in r ...   Quievryn, G; Goulart, M; Messer, J; Zhitkovich, A R01ES008786 Mol Cell Biochem (2001 Jun) 11678591 Exiting the NIEHS site 2001 
Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microsco ...   Anderson, D E; Trujillo, K M; Sung, P; Erickson, H P R01ES007061 J Biol Chem (2001 Oct 5) 11470800 Exiting the NIEHS site 2001 
Functional interactions among yeast Rad51 recombinase, Rad52 mediator, and replication protein A in ...   Song, B; Sung, P R01ES007061 J Biol Chem (2000 May 26) 10748203 Exiting the NIEHS site 2000 
Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase.   Chen, L; Trujillo, K; Sung, P; Tomkinson, A E R01ES007061 J Biol Chem (2000 Aug 25) 10854421 Exiting the NIEHS site 2000 
Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways.   Zeng, M; Narayanan, L; Xu, X S; Prolla, T A; Liskay, R M; Glazer, P M R01ES005775 Cancer Res (2000 Sep 1) 10987303 Exiting the NIEHS site 2000 
Loss of DNA-protein crosslinks from formaldehyde-exposed cells occurs through spontaneous hydrolysis ...   Quievryn, G; Zhitkovich, A R01ES008786 Carcinogenesis (2000 Aug) 10910961 Exiting the NIEHS site 2000 
Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions an ...   Andrew, S E; Xu, X S; Baross-Francis, A; Narayanan, L; Milhausen, K; Liskay, R M; Jirik, F R; ... R01ES005775 Carcinogenesis (2000 Jul) 10874005 Exiting the NIEHS site 2000 
Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1.   Petukhova, G; Sung, P; Klein, H R01ES007061 Genes Dev (2000 Sep 01) 10970884 Exiting the NIEHS site 2000 
Rats retain chromium in tissues following chronic ingestion of drinking water containing hexavalent ...   Sutherland, J E; Zhitkovich, A; Kluz, T; Costa, M R01ES008786 Biol Trace Elem Res (2000 Apr) 11049199 Exiting the NIEHS site 2000 
Recombination factors of Saccharomyces cerevisiae.   Sung, P; Trujillo, K M; Van Komen, S R01ES007061 Mutat Res (2000 Jun 30) 10915877 Exiting the NIEHS site 2000 
Reductive metabolism of Cr(VI) by cysteine leads to the formation of binary and ternary Cr--DNA addu ...   Zhitkovich, A; Shrager, S; Messer, J R01ES008786 Chem Res Toxicol (2000 Nov) 11087433 Exiting the NIEHS site 2000 
Superhelicity-driven homologous DNA pairing by yeast recombination factors Rad51 and Rad54.   R01ES007061 Mol Cell (2000 Sep) 11030336 Exiting the NIEHS site 2000 
Analysis of DNA-protein crosslinking activity of malondialdehyde in vitro.   Voitkun, V; Zhitkovich, A R01ES008786 Mutat Res (1999 Mar 08) 10064853 Exiting the NIEHS site 1999 
Different mutator phenotypes in Mlh1- versus Pms2-deficient mice.   Yao, X; Buermeyer, A B; Narayanan, L; Tran, D; Baker, S M; Prolla, T A; Glazer, P M; Liskay, ... R01ES005775 Proc Natl Acad Sci U S A (1999 Jun 08) 10359802 Exiting the NIEHS site 1999 
Single strand DNA binding and annealing activities in the yeast recombination factor Rad59.   Petukhova, G; Stratton, S A; Sung, P R01ES007061 J Biol Chem (1999 Nov 26) 10567339 Exiting the NIEHS site 1999 
The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 c ...   Clairmont, C A; Narayanan, L; Sun, K W; Glazer, P M; Sweasy, J B R01ES005775 Proc Natl Acad Sci U S A (1999 Aug 17) 10449735 Exiting the NIEHS site 1999 
Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA ...   Petukhova, G; Van Komen, S; Vergano, S; Klein, H; Sung, P R01ES007061 J Biol Chem (1999 Oct 08) 10506208 Exiting the NIEHS site 1999 
Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutageni ...   Voitkun, V; Zhitkovich, A; Costa, M R01ES008786 Nucleic Acids Res (1998 Apr 15) 9518499 Exiting the NIEHS site 1998 
Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95 ...   Trujillo, K M; Yuan, S S; Lee, E Y; Sung, P R01ES007061 J Biol Chem (1998 Aug 21) 9705271 Exiting the NIEHS site 1998 
Utilization of DNA-protein cross-links as a biomarker of chromium exposure.   Zhitkovich, A; Voitkun, V; Kluz, T; Costa, M R01ES008786 Environ Health Perspect (1998 Aug) 9703480 Exiting the NIEHS site 1998 
Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pm ...   Narayanan, L; Fritzell, J A; Baker, S M; Liskay, R M; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (1997 Apr 01) 9096356 Exiting the NIEHS site 1997 
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinas ...   Sung, P R01ES007061 J Biol Chem (1997 Nov 07) 9353267 Exiting the NIEHS site 1997 
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local bre ...   Turner, B C; Haffty, B G; Narayanan, L; Yuan, J; Havre, P A; Gumbs, A A; Kaplan, L; Burgaud, ... R01ES005775 Cancer Res (1997 Aug 1) 9242428 Exiting the NIEHS site 1997 
Role of DNA mismatch repair in the cytotoxicity of ionizing radiation.   Fritzell, J A; Narayanan, L; Baker, S M; Bronner, C E; Andrew, S E; Prolla, T A; Bradley, A; ... R01ES005775 Cancer Res (1997 Nov 15) 9371516 Exiting the NIEHS site 1997 
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promo ...   Sung, P R01ES007061 Genes Dev (1997 May 01) 9159392 Exiting the NIEHS site 1997 
Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription.   Lauder, S; Bankmann, M; Guzder, S N; Sung, P; Prakash, L; Prakash, S R01ES007061 Mol Cell Biol (1996 Dec) 8943333 Exiting the NIEHS site 1996 
Frequent spontaneous deletions at a shuttle vector locus in transgenic mice.   Leach, E G; Gunther, E J; Yeasky, T M; Gibson, L H; Yang-Feng, T L; Glazer, P M R01ES005775 Mutagenesis (1996 Jan) 8671715 Exiting the NIEHS site 1996 
Genetic instability induced by the tumor microenvironment.   Reynolds, T Y; Rockwell, S; Glazer, P M R01ES005775 Cancer Res (1996 Dec 15) 8971187 Exiting the NIEHS site 1996 
Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequenc ...   Raha, M; Wang, G; Seidman, M M; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (1996 Apr 02) 8610147 Exiting the NIEHS site 1996 
Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair.   Wang, G; Seidman, M M; Glazer, P M R01ES005775 Science (1996 Feb 09) 8628995 Exiting the NIEHS site 1996 
Recombination induced by triple-helix-targeted DNA damage in mammalian cells.   Faruqi, A F; Seidman, M M; Segal, D J; Carroll, D; Glazer, P M R01ES005775 Mol Cell Biol (1996 Dec) 8943337 Exiting the NIEHS site 1996 
Targeted mutagenesis mediated by the triple helix formation.   Glazer, P M; Wang, G; Havre, P A; Gunther, E J R01ES005775 Methods Mol Biol (1996) 8849999 Exiting the NIEHS site 1996 
Tissue specificity of spontaneous point mutations in lambda supF transgenic mice.   Leach, E G; Narayanan, L; Havre, P A; Gunther, E J; Yeasky, T M; Glazer, P M R01ES005775 Environ Mol Mutagen (1996) 8991078 Exiting the NIEHS site 1996 
Yeast Rad51 recombinase mediates polar DNA strand exchange in the absence of ATP hydrolysis.   Sung, P; Stratton, S A R01ES007061 J Biol Chem (1996 Nov 08) 8910403 Exiting the NIEHS site 1996 
Altered repair of targeted psoralen photoadducts in the context of an oligonucleotide-mediated tripl ...   Wang, G; Glazer, P M R01ES005775 J Biol Chem (1995 Sep 22) 7673252 Exiting the NIEHS site 1995 
DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that ...   Sung, P; Robberson, D L R01ES007061 Cell (1995 Aug 11) 7634335 Exiting the NIEHS site 1995 
Frequent T:A-->G:C transversions in X-irradiated mouse cells.   Yuan, J; Yeasky, T M; Rhee, M C; Glazer, P M R01ES005775 Carcinogenesis (1995 Jan) 7834808 Exiting the NIEHS site 1995 
Induction of p53 in mouse cells decreases mutagenesis by UV radiation.   Yuan, J; Yeasky, T M; Havre, P A; Glazer, P M R01ES005775 Carcinogenesis (1995 Oct) 7586125 Exiting the NIEHS site 1995 
Mutagenesis by 8-methoxypsoralen and 5-methylangelicin photoadducts in mouse fibroblasts: mutations ...   Gunther, E J; Yeasky, T M; Gasparro, F P; Glazer, P M R01ES005775 Cancer Res (1995 Mar 15) 7882323 Exiting the NIEHS site 1995 
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.   Wang, G; Levy, D D; Seidman, M M; Glazer, P M R01ES005775 Mol Cell Biol (1995 Mar) 7862165 Exiting the NIEHS site 1995 
Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: charac ...   Gasparro, F P; Havre, P A; Olack, G A; Gunther, E J; Glazer, P M R01ES005775 Nucleic Acids Res (1994 Jul 25) 8052539 Exiting the NIEHS site 1994 
High efficiency, restriction-deficient in vitro packaging extracts for bacteriophage lambda DNA usin ...   Gunther, E J; Murray, N E; Glazer, P M R01ES005775 Nucleic Acids Res (1993 Aug 11) 8396240 Exiting the NIEHS site 1993 
Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen.   Havre, P A; Gunther, E J; Gasparro, F P; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (1993 Aug 15) 8356097 Exiting the NIEHS site 1993 
Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide.   Havre, P A; Glazer, P M R01ES005775 J Virol (1993 Dec) 8230456 Exiting the NIEHS site 1993 
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