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Who We Fund: Publications associated with Organ Systems Or Disease Processes Research - Mitochondrial Disorders

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 95 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
A Nervous Breakdown that May Stop Autoimmune Diabetes.   Makhmutova, Madina; Rodriguez-Diaz, Rayner; Caicedo, Alejandro R33ES025673 Cell Metab (2020 02 04) 32023444 Exiting the NIEHS site 2020 
Characterization of Arsenic-Induced Cancer Stem-Like Cells.   Chang, Qingshan; Bi, Zhuoyue; Fu, Yao; Rice, M' Kya Anique; Zhang, Qian; Wadgaonkar, Priya; Al ... R01ES028263, R01ES028335 Methods Mol Biol (2020) 31960388 Exiting the NIEHS site 2020 
Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controll ...   Xie, Wenting; Jiao, Binxuan; Bai, Qing; Ilin, Vladimir A; Sun, Ming; Burton, Charles E; Kolodi ... R33ES025606 Elife (2020 Mar 17) 32180546 Exiting the NIEHS site 2020 
Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to ...   Kumar, Namrata; Moreno, Natália C; Feltes, Bruno C; Menck, Carlos Fm; Houten, Bennett Van R01ES019566, R33ES025606 Genet Mol Biol (2020) 32141475 Exiting the NIEHS site 2020 
CRISPR-Cas9 gene editing causes alternative splicing of the targeting mRNA.   Zhang, Qian; Fu, Yao; Thakur, Chitra; Bi, Zhuoyue; Wadgaonkar, Priya; Qiu, Yiran; Xu, Liping; ... P30ES020957, R01ES028263, R01ES028335 Biochem Biophys Res Commun (2020 Jul 12) 32460957 Exiting the NIEHS site 2020 
Cybrid technology.   Bacman, Sandra R; Nissanka, Nadee; Moraes, Carlos T R33ES025673 Methods Cell Biol (2020) 32183971 Exiting the NIEHS site 2020 
DNA-editing enzymes as potential treatments for heteroplasmic mtDNA diseases.   Zekonyte, U; Bacman, S R; Moraes, C T R33ES025673 J Intern Med (2020 Jun) 32176378 Exiting the NIEHS site 2020 
Iron and Heme Metabolism at the Leishmania-Host Interface.   Laranjeira-Silva, Maria Fernanda; Hamza, Iqbal; Pérez-Victoria, José M R33ES025661 Trends Parasitol (2020 Mar) 32005611 Exiting the NIEHS site 2020 
Mitochondrial DNA heteroplasmy in disease and targeted nuclease-based therapeutic approaches.   Nissanka, Nadee; Moraes, Carlos T R33ES025673 EMBO Rep (2020 Mar 04) 32073748 Exiting the NIEHS site 2020 
Myopathy reversion in mice after restauration of mitochondrial complex I.   Pereira, Claudia V; Peralta, Susana; Arguello, Tania; Bacman, Sandra R; Diaz, Francisca; Moraes ... R33ES025673 EMBO Mol Med (2020 Feb 07) 31916679 Exiting the NIEHS site 2020 
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer s ...   Bi, Zhuoyue; Zhang, Qian; Fu, Yao; Wadgaonkar, Priya; Zhang, Wenxuan; Almutairy, Bandar; Xu, ... P30ES020957, R01ES028263, R01ES028335 Theranostics (2020) 32226544 Exiting the NIEHS site 2020 
Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis.   Panzer, Julia K; Hiller, Helmut; Cohrs, Christian M; Almaça, Joana; Enos, Stephen J; Beery, Ma ... R33ES025673 JCI Insight (2020 Apr 23) 32324170 Exiting the NIEHS site 2020 
Secretory Functions of Macrophages in the Human Pancreatic Islet Are Regulated by Endogenous Puriner ...   Weitz, Jonathan R; Jacques-Silva, Carol; Qadir, Mirza Muhammed Fahd; Umland, Oliver; Pereira, E ... R33ES025673 Diabetes (2020 Jun) 32245801 Exiting the NIEHS site 2020 
The Local Paracrine Actions of the Pancreatic α-Cell.   Rodriguez-Diaz, Rayner; Tamayo, Alejandro; Hara, Manami; Caicedo, Alejandro R33ES025673 Diabetes (2020 04) 31882565 Exiting the NIEHS site 2020 
Analysis of Human Mitochondrial DNA Content by Southern Blotting and Nonradioactive Probe Hybridizat ...   Wheeler, Joel H; Young, Carolyn K J; Young, Matthew J R00ES022638 Curr Protoc Toxicol (2019 06) 30982231 Exiting the NIEHS site 2019 
Analysis of Mitochondrial DNA Polymorphisms in the Human Cell Lines HepaRG and SJCRH30.   Young, Matthew J; Jayaprakash, Anitha D; Young, Carolyn K J R00ES022638 Int J Mol Sci (2019 Jul 02) 31269646 Exiting the NIEHS site 2019 
Antibody-Linked Fluorogen-Activating Proteins for Antigen Detection and Cell Ablation.   Ackerman, Daniel S; Altun, Burcin; Kolodieznyi, Dmytro; Bruchez, Marcel P; Tsourkas, Andrew; Ja ... R33ES025606 Bioconjug Chem (2019 01 16) 30543409 Exiting the NIEHS site 2019 
Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction.   Qian, Wei; Kumar, Namrata; Roginskaya, Vera; Fouquerel, Elise; Opresko, Patricia L; Shiva, Sru ... R33ES025606 Proc Natl Acad Sci U S A (2019 09 10) 31451640 Exiting the NIEHS site 2019 
Comparison of HepaRG cells following growth in proliferative and differentiated culture conditions r ...   Young, Carolyn K J; Young, Matthew J R00ES022638 Cell Cycle (2019 02) 30755072 Exiting the NIEHS site 2019 
Connections between metabolism and epigenetics in cancers.   Thakur, Chitra; Chen, Fei R01ES028263, R01ES028335 Semin Cancer Biol (2019 08) 31185282 Exiting the NIEHS site 2019 
Damage sensor role of UV-DDB during base excision repair.   Jang, Sunbok; Kumar, Namrata; Beckwitt, Emily C; Kong, Muwen; Fouquerel, Elise; Rapić-Otrin, V ... R01ES019566, R33ES025606, T32ES007059 Nat Struct Mol Biol (2019 08) 31332353 Exiting the NIEHS site 2019 
Handling heme: The mechanisms underlying the movement of heme within and between cells.   Donegan, Rebecca K; Moore, Courtney M; Hanna, David A; Reddi, Amit R R33ES025661 Free Radic Biol Med (2019 03) 30092350 Exiting the NIEHS site 2019 
Hemozoin produced by mammals confers heme tolerance.   Pek, Rini H; Yuan, Xiaojing; Rietzschel, Nicole; Zhang, Jianbing; Jackson, Laurie; Nishibori, ... R33ES025661 Elife (2019 10 01) 31571584 Exiting the NIEHS site 2019 
Huntington's Disease: Astrocytes Shift to Fatty Acid Metabolism.   Van Houten, Bennett R33ES025606 Trends Endocrinol Metab (2019 09) 31399292 Exiting the NIEHS site 2019 
IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer.   Bartok, Adam; Weaver, David; Golenár, Tünde; Nichtova, Zuzana; Katona, Máté; Bánsághi, Száva; ... R33ES025672 Nat Commun (2019 08 19) 31427578 Exiting the NIEHS site 2019 
Linking metabolism to epigenetics in stem cells and cancer stem cells.   Chen, Fei P30ES020957, R01ES028263, R01ES028335 Semin Cancer Biol (2019 08) 31078639 Exiting the NIEHS site 2019 
Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA.   Fouquerel, Elise; Barnes, Ryan P; Wang, Hong; Opresko, Patricia L P30ES025128, R33ES025606 Methods Mol Biol (2019) 31127586 Exiting the NIEHS site 2019 
Metabolic and epigenetic reprogramming in the arsenic-induced cancer stem cells.   Li, Lingzhi; Bi, Zhuoyue; Wadgaonkar, Priya; Lu, Yongju; Zhang, Qian; Fu, Yao; Thakur, Chitra ... P30ES020957, R01ES028263, R01ES028335 Semin Cancer Biol (2019 08) 31009762 Exiting the NIEHS site 2019 
Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be ...   Seminotti, Bianca; Leipnitz, Guilhian; Karunanidhi, Anuradha; Kochersperger, Catherine; Roginska ... R33ES025606 Hum Mol Genet (2019 03 15) 30445591 Exiting the NIEHS site 2019 
New discoveries of mdig in the epigenetic regulation of cancers.   Zhang, Qian; Thakur, Chitra; Shi, Junwei; Sun, Jiaying; Fu, Yao; Stemmer, Paul; Chen, Fei P30ES020957, R01ES028263 Semin Cancer Biol (2019 08) 31276784 Exiting the NIEHS site 2019 
New quantitative approach reveals heterogeneity in mitochondrial structure-function relations in tum ...   Spurlock, Brian; Gupta, Priyanka; Basu, Malay Kumar; Mukherjee, Avik; Hjelmeland, Anita B; Darl ... R33ES025662 J Cell Sci (2019 05 02) 30910831 Exiting the NIEHS site 2019 
Peroxiredoxins in Cancer and Response to Radiation Therapies.   Forshaw, Tom E; Holmila, Reetta; Nelson, Kimberly J; Lewis, Joshua E; Kemp, Melissa L; Tsang, ... R33ES025645 Antioxidants (Basel) (2019 Jan 01) 30609657 Exiting the NIEHS site 2019 
Silver Nanoparticles Induce Mitochondrial Protein Oxidation in Lung Cells Impacting Cell Cycle and P ...   Holmila, Reetta J; Vance, Stephen A; King, S Bruce; Tsang, Allen W; Singh, Ravi; Furdui, Crist ... R33ES025645 Antioxidants (Basel) (2019 Nov 14) 31739476 Exiting the NIEHS site 2019 
Sorting mtDNA Species-the Role of nDNA-mtDNA Co-evolution.   Moraes, Carlos T R33ES025673 Cell Metab (2019 12 03) 31801053 Exiting the NIEHS site 2019 
Sulforaphane promotes chlamydial infection by suppressing mitochondrial protein oxidation and activa ...   Saez, Daniel; Dushime, Rosine; Wu, Hanzhi; Ramos Cordova, Lourdes B; Shukla, Kirtikar; Brown-Ha ... R33ES025645 Protein Sci (2019 01) 30367535 Exiting the NIEHS site 2019 
Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis.   Fouquerel, Elise; Barnes, Ryan P; Uttam, Shikhar; Watkins, Simon C; Bruchez, Marcel P; Opresko, ... R00ES027028, R33ES025606 Mol Cell (2019 07 11) 31101499 Exiting the NIEHS site 2019 
The impact of oxidative DNA damage and stress on telomere homeostasis.   Barnes, Ryan P; Fouquerel, Elise; Opresko, Patricia L R33ES025606 Mech Ageing Dev (2019 01) 29604323 Exiting the NIEHS site 2019 
Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effec ...   Li, Zhe; Forshaw, Tom E; Holmila, Reetta J; Vance, Stephen A; Wu, Hanzhi; Poole, Leslie B; Fur ... R33ES025645 Chem Res Toxicol (2019 03 18) 30784263 Exiting the NIEHS site 2019 
Zebrafish as a model system to delineate the role of heme and iron metabolism during erythropoiesis.   Zhang, Jianbing; Hamza, Iqbal R33ES025661 Mol Genet Metab (2019 11) 30626549 Exiting the NIEHS site 2019 
Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and ...   Kumar, Dhruv; New, Jacob; Vishwakarma, Vikalp; Joshi, Radhika; Enders, Jonathan; Lin, Fangchen ... R33ES025606 Cancer Res (2018 07 15) 29769197 Exiting the NIEHS site 2018 
Cys Links Heme: Stereo-orientation of Heme Transfer in Cytochrome c Biogenesis.   Yuan, Xiaojing; Hamza, Iqbal R33ES025661 J Mol Biol (2018 04 13) 29510174 Exiting the NIEHS site 2018 
DNA repair after oxidative stress: current challenges.   Van Houten, Bennett; Santa-Gonzalez, Gloria A; Camargo, Mauricio R33ES025606 Curr Opin Toxicol (2018 Feb) 29159324 Exiting the NIEHS site 2018 
Endoplasmic Reticulum-Mitochondrial Contactology: Structure and Signaling Functions.   Csordás, György; Weaver, David; Hajnóczky, György R33ES025672 Trends Cell Biol (2018 07) 29588129 Exiting the NIEHS site 2018 
H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulat ...   Nelson, Kimberly J; Bolduc, Jesalyn A; Wu, Hanzhi; Collins, John A; Burke, Elizabeth A; Reisz, ... R33ES025645 J Biol Chem (2018 10 19) 30190325 Exiting the NIEHS site 2018 
Heme and hemoglobin suppress amyloid β-mediated inflammatory activation of mouse astrocytes.   Sankar, Sitara B; Donegan, Rebecca K; Shah, Kajol J; Reddi, Amit R; Wood, Levi B R33ES025661 J Biol Chem (2018 07 20) 29871926 Exiting the NIEHS site 2018 
Heme bioavailability and signaling in response to stress in yeast cells.   Hanna, David A; Hu, Rebecca; Kim, Hyojung; Martinez-Guzman, Osiris; Torres, Matthew P; Reddi, ... R33ES025661 J Biol Chem (2018 08 10) 29921585 Exiting the NIEHS site 2018 
Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney.   Zhang, Jianbing; Chambers, Ian; Yun, Sijung; Phillips, John; Krause, Michael; Hamza, Iqbal R33ES025661 PLoS Genet (2018 09) 30248094 Exiting the NIEHS site 2018 
Label-Free Imaging of Heme Dynamics in Living Organisms by Transient Absorption Microscopy.   Chen, Andy Jing; Yuan, Xiaojing; Li, Junjie; Dong, Puting; Hamza, Iqbal; Cheng, Ji-Xin R33ES025661 Anal Chem (2018 03 06) 29401392 Exiting the NIEHS site 2018 
Loss of mdig expression enhances DNA and histone methylation and metastasis of aggressive breast can ...   Thakur, Chitra; Chen, Bailing; Li, Lingzhi; Zhang, Qian; Yang, Zeng-Quan; Chen, Fei P30ES020957, R01ES028263 Signal Transduct Target Ther (2018) 30254753 Exiting the NIEHS site 2018 
Mitochondria-targeted Probes for Imaging Protein Sulfenylation.   Holmila, Reetta J; Vance, Stephen A; Chen, Xiaofei; Wu, Hanzhi; Shukla, Kirtikar; Bharadwaj, M ... R33ES025645 Sci Rep (2018 04 27) 29703899 Exiting the NIEHS site 2018 
Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease.   Nissanka, Nadee; Moraes, Carlos T R33ES025673 FEBS Lett (2018 03) 29281123 Exiting the NIEHS site 2018 
Mitochondrial dynamics in adaptive and maladaptive cellular stress responses.   Eisner, Verónica; Picard, Martin; Hajnóczky, György R33ES025672 Nat Cell Biol (2018 07) 29950571 Exiting the NIEHS site 2018 
Mitochondrial Subtype Identification and Characterization.   Daniele, Joseph R; Heydari, Kartoosh; Dillin, Andrew R01ES021667 Curr Protoc Cytom (2018 07) 29944197 Exiting the NIEHS site 2018 
The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of del ...   Nissanka, Nadee; Bacman, Sandra R; Plastini, Melanie J; Moraes, Carlos T R33ES025673 Nat Commun (2018 06 27) 29950568 Exiting the NIEHS site 2018 
The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent ...   Zhang, Qian; Wu, Xueying; Chen, Peng; Liu, Limeng; Xin, Nan; Tian, Ye; Dillin, Andrew R01ES021667 Cell (2018 08 09) 30057120 Exiting the NIEHS site 2018 
Characterization of plasma labile heme in hemolytic conditions.   Gouveia, Zélia; Carlos, Ana R; Yuan, Xiaojing; Aires-da-Silva, Frederico; Stocker, Roland; Magh ... R33ES025661 FEBS J (2017 10) 28783254 Exiting the NIEHS site 2017 
Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in ...   Makhmutova, Madina; Liang, Tao; Gaisano, Herbert; Caicedo, Alejandro; Almaça, Joana R33ES025673 J Vis Exp (2017 Sep 13) 28930993 Exiting the NIEHS site 2017 
Convergence of The Nobel Fields of Telomere Biology and DNA Repair.   Fouquerel, Elise; Opresko, Patricia L R33ES025606 Photochem Photobiol (2017 01) 27861975 Exiting the NIEHS site 2017 
Current strategies towards therapeutic manipulation of mtDNA heteroplasmy.   Pereira, Claudia V; Moraes, Carlos T R33ES025673 Front Biosci (Landmark Ed) (2017 01 01) 27814659 Exiting the NIEHS site 2017 
Discovery of Heteroaromatic Sulfones As a New Class of Biologically Compatible Thiol-Selective Reage ...   Chen, Xiaofei; Wu, Hanzhi; Park, Chung-Min; Poole, Thomas H; Keceli, Gizem; Devarie-Baez, Nelm ... R33ES025645 ACS Chem Biol (2017 08 18) 28687042 Exiting the NIEHS site 2017 
Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.   Keyes, Jeremiah D; Parsonage, Derek; Yammani, Rama D; Rogers, LeAnn C; Kesty, Chelsea; Furdui, ... R33ES025645 Free Radic Biol Med (2017 11) 28843779 Exiting the NIEHS site 2017 
Heme Gazing: Illuminating Eukaryotic Heme Trafficking, Dynamics, and Signaling with Fluorescent Heme ...   Hanna, David A; Martinez-Guzman, Osiris; Reddi, Amit R R33ES025661 Biochemistry (2017 04 04) 28316240 Exiting the NIEHS site 2017 
Inter-organ signalling by HRG-7 promotes systemic haem homeostasis.   Sinclair, Jason; Pinter, Katherine; Samuel, Tamika; Beardsley, Simon; Yuan, Xiaojing; Zhang, J ... R33ES025661 Nat Cell Biol (2017 Jul) 28581477 Exiting the NIEHS site 2017 
Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance.   Young, Matthew J R00ES022638 Front Mol Biosci (2017) 29214156 Exiting the NIEHS site 2017 
POLB: A new role of DNA polymerase beta in mitochondrial base excision repair.   Kaufman, Brett A; Van Houten, Bennett R01ES019566, R33ES025606 DNA Repair (Amst) (2017 12) 29129598 Exiting the NIEHS site 2017 
Spectral properties of the zebrafish visual motor response.   Burton, Charles E; Zhou, Yangzhong; Bai, Qing; Burton, Edward A R33ES025606 Neurosci Lett (2017 04 12) 28267562 Exiting the NIEHS site 2017 
The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat.   Long, David; Wu, Hanzhi; Tsang, Allen W; Poole, Leslie B; Yoza, Barbara K; Wang, Xianfeng; Vac ... R33ES025645 Sci Rep (2017 09 08) 28887543 Exiting the NIEHS site 2017 
The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.   Mauney, Christopher H; Rogers, LeAnn C; Harris, Reuben S; Daniel, Larry W; Devarie-Baez, Nelmi ... R33ES025645 Antioxid Redox Signal (2017 Dec 01) 28398823 Exiting the NIEHS site 2017 
Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors.   Hanna, David A; Harvey, Raven M; Martinez-Guzman, Osiris; Yuan, Xiaojing; Chandrasekharan, Bind ... R33ES025661 Proc Natl Acad Sci U S A (2016 07 05) 27247412 Exiting the NIEHS site 2016 
Heme Mobilization in Animals: A Metallolipid's Journey.   Reddi, Amit R; Hamza, Iqbal R33ES025661 Acc Chem Res (2016 06 21) 27254265 Exiting the NIEHS site 2016 
Human mitochondrial DNA replication machinery and disease.   Young, Matthew J; Copeland, William C R00ES022638 Curr Opin Genet Dev (2016 06) 27065468 Exiting the NIEHS site 2016 
Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response.   Kim, Hyun-Eui; Grant, Ana Rodrigues; Simic, Milos S; Kohnz, Rebecca A; Nomura, Daniel K; Durieu ... R01ES021667 Cell (2016 Sep 08) 27610574 Exiting the NIEHS site 2016 
Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis.   Berendzen, Kristen M; Durieux, Jenni; Shao, Li-Wa; Tian, Ye; Kim, Hyun-Eui; Wolff, Suzanne; Li ... R01ES021667 Cell (2016 Sep 08) 27610575 Exiting the NIEHS site 2016 
Nuclear mechanical resilience but not stiffness is modulated by αII-spectrin.   Armiger, Travis J; Spagnol, Stephen T; Dahl, Kris Noel R33ES025606 J Biomech (2016 12 08) 27836504 Exiting the NIEHS site 2016 
Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface.   Booth, David M; Enyedi, Balázs; Geiszt, Miklós; Várnai, Péter; Hajnóczky, György R33ES025672 Mol Cell (2016 07 21) 27397688 Exiting the NIEHS site 2016 
Regulation of intracellular heme trafficking revealed by subcellular reporters.   Yuan, Xiaojing; Rietzschel, Nicole; Kwon, Hanna; Walter Nuno, Ana Beatriz; Hanna, David A; Phil ... R33ES025661 Proc Natl Acad Sci U S A (2016 08 30) 27528661 Exiting the NIEHS site 2016 
Subcellular ROS imaging methods: Relevance for the study of calcium signaling.   Booth, David M; Joseph, Suresh K; Hajnóczky, György R33ES025672 Cell Calcium (2016 Aug) 27209367 Exiting the NIEHS site 2016 
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.   Merkwirth, Carsten; Jovaisaite, Virginija; Durieux, Jenni; Matilainen, Olli; Jordan, Sabine D; ... R01ES021667 Cell (2016 May 19) 27133168 Exiting the NIEHS site 2016 
A new mitochondrial pool of cyclin E, regulated by Drp1, is linked to cell-density-dependent cell pr ...   Parker, Danitra J; Iyer, Archana; Shah, Shikha; Moran, Aida; Hjelmeland, Anita B; Basu, Malay ... R33ES025662 J Cell Sci (2015 Nov 15) 26446260 Exiting the NIEHS site 2015 
Endocrine aspects of organelle stress—cell non-autonomous signaling of mitochondria and the ER.   Schinzel, Robert; Dillin, Andrew R01ES021667 Curr Opin Cell Biol (2015 Apr) 25677685 Exiting the NIEHS site 2015 
Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity.   Douglas, Peter M; Baird, Nathan A; Simic, Milos S; Uhlein, Sarah; McCormick, Mark A; Wolff, Su ... R01ES021667 Cell Rep (2015 Aug 18) 26257177 Exiting the NIEHS site 2015 
Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy.   Wilkinson, Deepti S; Jariwala, Jinel S; Anderson, Ericka; Mitra, Koyel; Meisenhelder, Jill; Cha ... R01ES021667 Mol Cell (2015 Jan 8) 25544559 Exiting the NIEHS site 2015 
POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial local ...   Young, Matthew J; Humble, Margaret M; DeBalsi, Karen L; Sun, Kathie Y; Copeland, William C R00ES022638 Hum Mol Genet (2015 Sep 15) 26123486 Exiting the NIEHS site 2015 
The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.   Heimbucher, Thomas; Liu, Zheng; Bossard, Carine; McCloskey, Richard; Carrano, Andrea C; Riedel, ... R01ES021667 Cell Metab (2015 Jul 7) 26154057 Exiting the NIEHS site 2015 
A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevi ...   Carrano, Andrea C; Dillin, Andrew; Hunter, Tony R01ES021667 Nat Commun (2014 May 08) 24805825 Exiting the NIEHS site 2014 
Differential scales of protein quality control.   Wolff, Suzanne; Weissman, Jonathan S; Dillin, Andrew R01ES021667 Cell (2014 Mar 27) 24679526 Exiting the NIEHS site 2014 
Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension.   Patti, Gary J; Tautenhahn, Ralf; Johannsen, Darcy; Kalisiak, Ewa; Ravussin, Eric; Brüning, Jen ... R01ES021667 Metabolomics (2014 Aug 1) 25530742 Exiting the NIEHS site 2014 
Profile of Kazutoshi Mori and Peter Walter, 2014 Lasker Basic Medical Research awardees: The unfolde ...   Dillin, Andrew R01ES021667 Proc Natl Acad Sci U S A (2014 Dec 16) 25480547 Exiting the NIEHS site 2014 
The disposable soma theory of aging in reverse.   Douglas, Peter M; Dillin, Andrew R01ES021667 Cell Res (2014 Jan) 24189044 Exiting the NIEHS site 2014 
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity.   Riedel, Christian G; Dowen, Robert H; Lourenco, Guinevere F; Kirienko, Natalia V; Heimbucher, T ... R01ES021667 Nat Cell Biol (2013 May) 23604319 Exiting the NIEHS site 2013 
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.   Lapierre, Louis R; De Magalhaes Filho, C Daniel; McQuary, Philip R; Chu, Chu-Chiao; Visvikis, O ... R01ES021667 Nat Commun (2013) 23925298 Exiting the NIEHS site 2013 
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.   Russell, Ryan C; Tian, Ye; Yuan, Haixin; Park, Hyun Woo; Chang, Yu-Yun; Kim, Joungmok; Kim, H ... R01ES021667 Nat Cell Biol (2013 Jul) 23685627 Exiting the NIEHS site 2013 
Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA ...   Parrish, Angela R; She, Xingyu; Xiang, Zheng; Coin, Irene; Shen, Zhouxin; Briggs, Steven P; Di ... R01ES021667 ACS Chem Biol (2012 Jul 20) 22554080 Exiting the NIEHS site 2012 
Temporal requirements of heat shock factor-1 for longevity assurance.   Volovik, Yuli; Maman, Moria; Dubnikov, Tatyana; Bejerano-Sagie, Michal; Joyce, Derek; Kapernick ... R01ES021667 Aging Cell (2012 Jun) 22360389 Exiting the NIEHS site 2012 
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia ...   Kim, Hyungsoo; Scimia, Maria C; Wilkinson, Deepti; Trelles, Ramon D; Wood, Malcolm R; Bowtell, ... R01ES021667 Mol Cell (2011 Nov 18) 22099302 Exiting the NIEHS site 2011 
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