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Who We Fund: Publication Detail

Project Title: OXIDANT AND ENVIRONMENTAL TOXICANT-INDUCED EFFECTS COMPROMISE LIGATION IN DNA REPAIR
PI: Caglayan, Melike
Institution: University Of Florida
Grant Number: R00ES026191

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 10 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.grantpubdetail&&grant_number=R00ES026191&format=excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Structures of LIG1 engaging with mutagenic mismatches inserted by polβ in base excision repair.   Caglayan, Melike R00ES026191 FASEB J (2022 May) 35553977 Exiting the NIEHS site 2022 
DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized and mismatch nucleotide inse ...   Kamble, Pradnya; Hall, Kalen; Chandak, Mahesh; Tang, Qun; Çağlayan, Melike R00ES026191 J Biol Chem (2021 Jan-Jun) 33600799 Exiting the NIEHS site 2021 
The scaffold protein XRCC1 stabilizes the formation of polβ/gap DNA and ligase IIIα/nick DNA complex ...   Tang, Qun; Çağlayan, Melike R00ES026191 J Biol Chem (2021 09) 34339737 Exiting the NIEHS site 2021 
DNA ligase I variants fail in the ligation of mutagenic repair intermediates with mismatches and oxi ...   Tang, Qun; Kamble, Pradnya; Çağlayan, Melike R00ES026191 Mutagenesis (2020 12 01) 32914844 Exiting the NIEHS site 2020 
Pol β gap filling, DNA ligation and substrate-product channeling during base excision repair opposit ...   Çağlayan, Melike R00ES026191 DNA Repair (Amst) (2020 11) 32853828 Exiting the NIEHS site 2020 
Pol μ ribonucleotide insertion opposite 8-oxodG facilitates the ligation of premutagenic DNA repair ...   Çağlayan, Melike R00ES026191 Sci Rep (2020 01 22) 31969622 Exiting the NIEHS site 2020 
The ligation of pol β mismatch insertion products governs the formation of promutagenic base excisio ...   Çağlayan, Melike R00ES026191 Nucleic Acids Res (2020 04 17) 32140717 Exiting the NIEHS site 2020 
Interplay between DNA Polymerases and DNA Ligases: Influence on Substrate Channeling and the Fidelit ...   Çağlayan, Melike R00ES026191 J Mol Biol (2019 05 17) 31034893 Exiting the NIEHS site 2019 
Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals promutagenic DNA repair inter ...   Çağlayan, Melike; Wilson, Samuel H R00ES026191 Nat Commun (2018 10 11) 30310068 Exiting the NIEHS site 2018 
Role of DNA polymerase β oxidized nucleotide insertion in DNA ligation failure.   Çaglayan, Melike; Wilson, Samuel H R00ES026191 J Radiat Res (2017 Sep 01) 28992331 Exiting the NIEHS site 2017 
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