Project Title: | ENDOTHELIAL PROGENITOR CELLS AND PARTICULATE AIR POLLUTION |
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PI: | O'Toole, Timothy E |
Institution: | University Of Louisville |
Grant Number: | R01ES019217 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Big Data and ASCVD Risk Prediction: Building a Better Mouse Trap? | Nasir, Khurram; DeFilippis, Andrew | R01ES019217, R01ES029846 | J Am Coll Cardiol (2022 Mar 29) | 35331411 | 2022 |
Cardiovascular Effects of Particulate Air Pollution. | Bhatnagar, Aruni | P42ES023716, R01ES019217, R01ES029846 | Annu Rev Med (2022 Jan 27) | 34644154 | 2022 |
Environmental exposure to volatile organic compounds is associated with endothelial injury. | Riggs, Daniel W; Malovichko, Marina V; Gao, Hong; McGraw, Katlyn E; Taylor, Breandon S; Krivokh ... | P42ES023716, R01ES019217, R01ES029846, T32ES011564 | Toxicol Appl Pharmacol (2022 Feb 15) | 35045333 | 2022 |
Polystyrene bead ingestion promotes adiposity and cardiometabolic disease in mice. | Zhao, Jingjing; Gomes, Daniel; Jin, Lexiao; Mathis, Steven P; Li, Xiaohong; Rouchka, Eric C; B ... | P30ES030283, R01ES019217 | Ecotoxicol Environ Saf (2022 Mar 01) | 35093814 | 2022 |
Endothelial progenitor cells as critical mediators of environmental air pollution-induced cardiovasc ... | Singh, Parul; O'Toole, Timothy E; Conklin, Daniel J; Hill, Bradford G; Haberzettl, Petra | P30ES030283, R01ES019217, R01ES027881, R01ES027881, R01ES028268, R01ES028268 | Am J Physiol Heart Circ Physiol (2021 Apr 01) | 33606580 | 2021 |
Exposure to Fine Particulate Matter Air Pollution Alters mRNA and miRNA Expression in Bone Marrow-De ... | Li, Xiaohong; Haberzettl, Petra; Conklin, Daniel J; Bhatnagar, Aruni; Rouchka, Eric C; Zhang, ... | P30ES030283, R01ES019217, R01ES027881, R01ES027881, R01ES028268, R01ES028268 | Genes (Basel) (2021 07 10) | 34356074 | 2021 |
Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated ... | McGraw, Katlyn E; Riggs, Daniel W; Rai, Shesh; Navas-Acien, Ana; Xie, Zhengzhi; Lorkiewicz, Pa ... | P30ES009089, P30ES030283, P42ES023716, R01ES019217, R01ES029846, R01ES029967, T32ES011564 | Environ Res (2021 May) | 33636185 | 2021 |
Residential proximity to greenness mitigates the hemodynamic effects of ambient air pollution. | Riggs, Daniel W; Yeager, Ray; Conklin, Daniel J; DeJarnett, Natasha; Keith, Rachel J; DeFilippi ... | P30ES030283, P42ES023716, R01ES019217, R01ES029846 | Am J Physiol Heart Circ Physiol (2021 Mar 01) | 33416460 | 2021 |
Urinary Levels of the Acrolein Conjugates of Carnosine Are Associated with Cardiovascular Disease Ri ... | O'Toole, Timothy E; Li, Xiaohong; Riggs, Daniel W; Hoetker, David J; Baba, Shahid P; Bhatnagar, ... | P30ES030283, R01ES019217 | Int J Mol Sci (2021 Jan 30) | 33573153 | 2021 |
Acute and chronic vascular effects of inhaled crotonaldehyde in mice: Role of TRPA1. | Lynch, Jordan; Jin, Lexiao; Richardson, Andre; Jagatheesan, Ganapathy; Lorkiewicz, Pawel; Xie, ... | R01ES019217, T32ES011564 | Toxicol Appl Pharmacol (2020 09 01) | 32634517 | 2020 |
Association between residential greenness and exposure to volatile organic compounds. | Yeager, Ray; Riggs, Daniel W; DeJarnett, Natasha; Srivastava, Shweta; Lorkiewicz, Pawel; Xie, ... | P42ES023716, R01ES019217, R01ES029846 | Sci Total Environ (2020 Mar 10) | 31865083 | 2020 |
Exposure to airborne fine particulate matter is associated with impaired endothelial function and bi ... | Riggs, Daniel W; Zafar, Nagma; Krishnasamy, Sathya; Yeager, Ray; Rai, Shesh N; Bhatnagar, Arun ... | P42ES023716, R01ES019217, R01ES029846 | Environ Res (2020 01) | 31718786 | 2020 |
Green environments and cardiovascular health. | Yeager, Ray A; Smith, Theodore R; Bhatnagar, Aruni | R01ES019217, R01ES029846 | Trends Cardiovasc Med (2020 05) | 31248691 | 2020 |
Protocol to assess the efficacy of carnosine supplementation in mitigating the adverse cardiovascula ... | O'Toole, Timothy E; Amraotkar, Alok A; DeFilippis, Andrew P; Rai, Shesh N; Keith, Rachel J; Bab ... | P30ES030283, R01ES019217 | BMJ Open (2020 12 28) | 33372072 | 2020 |
Tobacco Smoke and Endothelial Dysfunction: Role of Aldehydes? | Lynch, Jordan; Jin, Lexiao; Richardson, Andre; Conklin, Daniel J | P42ES023716, R01ES019217, T32ES011564 | Curr Hypertens Rep (2020 08 28) | 32857217 | 2020 |
Urinary levels of the acrolein conjugates of carnosine are associated with inhaled toxicants. | O'Toole, Timothy E; Li, Xiaohong; Riggs, Daniel W; Hoetker, David J; Yeager, Ray; Lorkiewicz, ... | P30ES030283, R01ES019217 | Inhal Toxicol (2020 Nov - Dec) | 33179563 | 2020 |
Acute exposure to air pollution is associated with novel changes in blood levels of endothelin-1 and ... | Finch, Jordan; Riggs, Daniel W; O'Toole, Timothy E; Pope 3rd, C Arden; Bhatnagar, Aruni; Conkli ... | R01ES019217, T32ES011564 | AIMS Environ Sci (2019) | 32309625 | 2019 |
Benzene Exposure Induces Insulin Resistance in Mice. | Abplanalp, Wesley T; Wickramasinghe, Nalinie S; Sithu, Srinivas D; Conklin, Daniel J; Xie, Zhen ... | P42ES023716, R01ES019217 | Toxicol Sci (2019 02 01) | 30346588 | 2019 |
Cardiovascular injury induced by tobacco products: assessment of risk factors and biomarkers of harm ... | Conklin, Daniel J; Schick, Suzaynn; Blaha, Michael J; Carll, Alex; DeFilippis, Andrew; Ganz, P ... | P42ES023716, R01ES019217 | Am J Physiol Heart Circ Physiol (2019 Apr 01) | 30707616 | 2019 |
Carnosine Supplementation Mitigates the Deleterious Effects of Particulate Matter Exposure in Mice. | Abplanalp, Wesley; Haberzettl, Petra; Bhatnagar, Aruni; Conklin, Daniel J; O'Toole, Timothy E | R01ES019217 | J Am Heart Assoc (2019 07 02) | 31234700 | 2019 |
Cardiac mesenchymal cells from diabetic mice are ineffective for cell therapy-mediated myocardial re ... | Mehra, Parul; Guo, Yiru; Nong, Yibing; Lorkiewicz, Pawel; Nasr, Marjan; Li, Qianhong; Muthusam ... | R01ES019217, R01ES028268, R01ES028268 | Basic Res Cardiol (2018 10 23) | 30353243 | 2018 |
Cardiovascular Disease and Fine Particulate Matter: Lessons and Limitations of an Integrated Exposur ... | Pope 3rd, C Arden; Cohen, Aaron J; Burnett, Richard T | R01ES019217 | Circ Res (2018 Jun 08) | 29880499 | 2018 |
Circulating angiogenic stem cells in type 2 diabetes are associated with glycemic control and endoth ... | Zafar, Nagma; Krishnasamy, Sathya S; Shah, Jasmit; Rai, Shesh N; Riggs, Daniel W; Bhatnagar, A ... | R01ES019217 | PLoS One (2018) | 30321232 | 2018 |
Defining the Human Envirome: An Omics Approach for Assessing the Environmental Risk of Cardiovascula ... | Riggs, Daniel W; Yeager, Ray A; Bhatnagar, Aruni | P42ES023716, R01ES019217 | Circ Res (2018 Apr 27) | 29700071 | 2018 |
Inhalation of Fine Particulate Matter Impairs Endothelial Progenitor Cell Function Via Pulmonary Oxi ... | Haberzettl, Petra; Conklin, Daniel J; Abplanalp, Wesley T; Bhatnagar, Aruni; O'Toole, Timothy E | R01ES019217 | Arterioscler Thromb Vasc Biol (2018 Jan) | 29191925 | 2018 |
Benzene exposure is associated with cardiovascular disease risk. | Abplanalp, Wesley; DeJarnett, Natasha; Riggs, Daniel W; Conklin, Daniel J; McCracken, James P; ... | R01ES019217 | PLoS One (2017) | 28886060 | 2017 |
Biomarkers of Chronic Acrolein Inhalation Exposure in Mice: Implications for Tobacco Product-Induced ... | Conklin, Daniel J; Malovichko, Marina V; Zeller, Iris; Das, Trinath P; Krivokhizhina, Tatiana V ... | R01ES019217 | Toxicol Sci (2017 Aug 01) | 28482051 | 2017 |
Environmental Determinants of Cardiovascular Disease. | Bhatnagar, Aruni | R01ES019217 | Circ Res (2017 Jul 07) | 28684622 | 2017 |
Response by Bhatnagar to Letter Regarding Article, "Environmental Determinants of Cardiovascular Dis ... | Bhatnagar, Aruni | R01ES019217 | Circ Res (2017 Sep 29) | 28963194 | 2017 |
Air Pollution-Induced Vascular Dysfunction: Potential Role of Endothelin-1 (ET-1) System. | Finch, Jordan; Conklin, Daniel J | R01ES019217, T32ES011564 | Cardiovasc Toxicol (2016 Jul) | 26148452 | 2016 |
Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish betwee ... | DeFilippis, Andrew P; Chernyavskiy, Ilya; Amraotkar, Alok R; Trainor, Patrick J; Kothari, Shali ... | R01ES019217 | J Thromb Thrombolysis (2016 Jul) | 26510751 | 2016 |
Enhanced Integrin α4β1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progeni ... | Abplanalp, Wesley T; Conklin, Daniel J; Cantor, Joseph M; Ginsberg, Mark H; Wysoczynski, Marcin ... | R01ES019217 | Diabetes (2016 Nov) | 27495221 | 2016 |
Exposure to Fine Particulate Air Pollution Causes Vascular Insulin Resistance by Inducing Pulmonary ... | Haberzettl, Petra; O'Toole, Timothy E; Bhatnagar, Aruni; Conklin, Daniel J | R01ES019217 | Environ Health Perspect (2016 Dec) | 27128347 | 2016 |
Exposure to Fine Particulate Air Pollution Is Associated With Endothelial Injury and Systemic Inflam ... | Pope 3rd, C Arden; Bhatnagar, Aruni; McCracken, James P; Abplanalp, Wesley; Conklin, Daniel J; ... | R01ES019217 | Circ Res (2016 Nov 11) | 27780829 | 2016 |
Residential Proximity to Major Roadways Is Associated With Increased Levels of AC133+ Circulating An ... | DeJarnett, Natasha; Yeager, Ray; Conklin, Daniel J; Lee, Jongmin; O'Toole, Timothy E; McCracken ... | R01ES019217 | Arterioscler Thromb Vasc Biol (2015 Nov) | 26293462 | 2015 |
Short-Term Exposure to Fine Particulate Matter Air Pollution Is Preferentially Associated With the R ... | Pope, C Arden; Muhlestein, Joseph B; Anderson, Jeffrey L; Cannon, John B; Hales, Nicholas M; Me ... | R01ES019217 | J Am Heart Assoc (2015 Dec 08) | 26645834 | 2015 |
Acrolein decreases endothelial cell migration and insulin sensitivity through induction of let-7a. | O'Toole, Timothy E; Abplanalp, Wesley; Li, Xiaohong; Cooper, Nigel; Conklin, Daniel J; Haberzet ... | R01ES019217 | Toxicol Sci (2014 Aug 01) | 24812010 | 2014 |
Acrolein exposure is associated with increased cardiovascular disease risk. | DeJarnett, Natasha; Conklin, Daniel J; Riggs, Daniel W; Myers, John A; O'Toole, Timothy E; Hamz ... | R01ES019217 | J Am Heart Assoc (2014 Aug 06) | 25099132 | 2014 |
Exposure to ambient air fine particulate matter prevents VEGF-induced mobilization of endothelial pr ... | Haberzettl, Petra; Lee, Jongmin; Duggineni, Dheeraj; McCracken, James; Bolanowski, Duane; O'Too ... | R01ES019217 | Environ Health Perspect (2012 Jun) | 22418586 | 2012 |
Episodic exposure to fine particulate air pollution decreases circulating levels of endothelial prog ... | O'Toole, Timothy E; Hellmann, Jason; Wheat, Laura; Haberzettl, Petra; Lee, Jongmin; Conklin, D ... | R01ES019217 | Circ Res (2010 Jul 23) | 20595651 | 2010 |