| Project Title: | NEUROINFLAMMATION AND DEVELOPMENTAL VULNERABILITY TO MANGANESE TOXICITY |
|---|---|
| PI: | Tjalkens, Ronald |
| Institution: | Colorado State University |
| Grant Number: | R01ES021656 |
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Viewing 33 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Microglia-specific knock-out of NF-κB/IKK2 increases the accumulation of misfolded α-synuclein throu ... | Rocha, Savannah M; Kirkley, Kelly S; Chatterjee, Debotri; Aboellail, Tawfik A; Smeyne, Richard ... | R01ES021656 | Glia (2023 May 18) |
37199240
|
2023 |
| A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflamm ... | Rocha, Savannah M; Fagre, Anna C; Latham, Amanda S; Cummings, Jason E; Aboellail, Tawfik A; Rei ... | R01ES021656, R01ES030937 | Front Immunol (2022) |
35250984
|
2022 |
| Rotenone induces regionally distinct α-synuclein protein aggregation and activation of glia prior to ... | Rocha, Savannah M; Bantle, Collin M; Aboellail, Tawfik; Chatterjee, Debotri; Smeyne, Richard J; ... | R01ES021656 | Neurobiol Dis (2022 Jun 01) |
35257879
|
2022 |
| A Low-Cost, Autonomous Gait Detection and Estimation System for Analyzing Gait Impairments in Mice. | Damale, Pranav U; Chong, Edwin K P; Hammond, Sean L; Tjalkens, Ronald B | R01ES021656, R01ES030937 | J Healthc Eng (2021) |
34804462
|
2021 |
| Astrocyte inflammatory signaling mediates α-synuclein aggregation and dopaminergic neuronal loss fol ... | Bantle, Collin M; Rocha, Savannah M; French, C Tenley; Phillips, Aaron T; Tran, Kevin; Olson, ... | R01ES021656, R01ES030937 | Exp Neurol (2021 Dec) |
34454938
|
2021 |
| Can We Panelize Seizure? | Roberts, Ruth; Authier, Simon; Mellon, R Daniel; Morton, Michael; Suzuki, Ikuro; Tjalkens, Ron ... | R01ES021656 | Toxicol Sci (2021 01 06) |
33165543
|
2021 |
| A Potent SARS-CoV-2 Neutralizing Human Monoclonal Antibody That Reduces Viral Burden and Disease Sev ... | Fagre, Anna C; Manhard, John; Adams, Rachel; Eckley, Miles; Zhan, Shijun; Lewis, Juliette; Roc ... | R01ES021656, R01ES030937 | Front Immunol (2020) |
33391285
|
2020 |
| NF-κB Signaling in Astrocytes Modulates Brain Inflammation and Neuronal Injury Following Sequential ... | Hammond, Sean L; Bantle, Collin M; Popichak, Katriana A; Wright, Katie A; Thompson, Delaney; Fo ... | R01ES021656 | Toxicol Sci (2020 10 01) |
32692843
|
2020 |
| Nuclear receptor 4A2 (NR4A2) is a druggable target for glioblastomas. | Karki, Keshav; Li, Xi; Jin, Un-Ho; Mohankumar, Kumaravel; Zarei, Mahsa; Michelhaugh, Sharon K; ... | P30ES029067, R01ES021656, R01ES030937, T32ES026568 | J Neurooncol (2020 Jan) |
31754919
|
2020 |
| Experimental Zika virus infection of Jamaican fruit bats (Artibeus jamaicensis) and possible entry o ... | Malmlov, Ashley; Bantle, Collin; Aboellail, Tawfik; Wagner, Kaitlyn; Campbell, Corey L; Eckley, ... | R01ES021656 | PLoS Negl Trop Dis (2019 02) |
30716104
|
2019 |
| Genetic suppression of IKK2/NF-κB in astrocytes inhibits neuroinflammation and reduces neuronal loss ... | Kirkley, Kelly S; Popichak, Katriana A; Hammond, Sean L; Davies, Cecilia; Hunt, Lindsay; Tjalke ... | R01ES021656 | Neurobiol Dis (2019 07) |
30818064
|
2019 |
| Structure-dependent activation of gene expression by bis-indole and quinoline-derived activators of ... | Li, Xi; Tjalkens, Ronald B; Shrestha, Rupesh; Safe, Stephen | P30ES029067, R01ES021656, T32ES026568 | Chem Biol Drug Des (2019 10) |
31102570
|
2019 |
| A novel diindolylmethane analog, 1,1-bis(3'-indolyl)-1-(p-chlorophenyl) methane, inhibits the tumor ... | Afzali, Maryam F; Popichak, Katriana A; Burton, Lindsey H; Klochak, Anna L; Wilson, William J; ... | R01ES021656 | Mol Immunol (2018 09) |
29870816
|
2018 |
| Compensatory Expression of Nur77 and Nurr1 Regulates NF-κB-Dependent Inflammatory Signaling in Astro ... | Popichak, Katriana A; Hammond, Sean L; Moreno, Julie A; Afzali, Maryam F; Backos, Donald S; Sla ... | R01ES021656 | Mol Pharmacol (2018 10) |
30111648
|
2018 |
| Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese. | Popichak, Katriana A; Afzali, Maryam F; Kirkley, Kelly S; Tjalkens, Ronald B | R01ES021656 | J Neuroinflammation (2018 Nov 21) |
30463564
|
2018 |
| The Nurr1 Ligand,1,1-bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Ne ... | Hammond, Sean L; Popichak, Katriana A; Li, Xi; Hunt, Lindsay G; Richman, Evan H; Damale, Prana ... | R01ES021656 | J Pharmacol Exp Ther (2018 Jun) |
29626009
|
2018 |
| Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intrac ... | Hammond, Sean L; Leek, Ashley N; Richman, Evan H; Tjalkens, Ronald B | R01ES021656 | PLoS One (2017) |
29244806
|
2017 |
| Inflammatory Activation of Microglia and Astrocytes in Manganese Neurotoxicity. | Tjalkens, Ronald B; Popichak, Katriana A; Kirkley, Kelly A | R01ES021656 | Adv Neurobiol (2017) |
28889267
|
2017 |
| Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity. | Kirkley, Kelly S; Popichak, Katriana A; Afzali, Maryam F; Legare, Marie E; Tjalkens, Ronald B | R01ES021656 | J Neuroinflammation (2017 May 05) |
28476157
|
2017 |
| Spontaneous Development of Cutaneous Squamous Cell Carcinoma in Mice with Cell-specific Deletion of ... | Kirkley, Kelly S; Walton, Kelly D; Duncan, Colleen; Tjalkens, Ronald B | R01ES021656 | Comp Med (2017 Oct 01) |
28935002
|
2017 |
| Entry Sites of Venezuelan and Western Equine Encephalitis Viruses in the Mouse Central Nervous Syste ... | Phillips, Aaron T; Rico, Amber B; Stauft, Charles B; Hammond, Sean L; Aboellail, Tawfik A; Tjal ... | R01ES021656 | J Virol (2016 Jun 15) |
27053560
|
2016 |
| Nuclear receptor 4A (NR4A) family - orphans no more. | Safe, Stephen; Jin, Un-Ho; Morpurgo, Benjamin; Abudayyeh, Ala; Singh, Mandip; Tjalkens, Ronald ... | P30ES005022, R01ES021656 | J Steroid Biochem Mol Biol (2016 Mar) |
25917081
|
2016 |
| Venezuelan and western equine encephalitis virus E1 liposome antigen nucleic acid complexes protect ... | Rico, Amber B; Phillips, Aaron T; Schountz, Tony; Jarvis, Donald L; Tjalkens, Ronald B; Powers, ... | R01ES021656 | Virology (2016 Dec) |
27632563
|
2016 |
| A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hyd ... | Hammond, Sean L; Safe, Stephen; Tjalkens, Ronald B | R01ES021656 | Neurosci Lett (2015 Oct 21) |
26383113
|
2015 |
| Angiotensin II regulates brain (pro)renin receptor expression through activation of cAMP response el ... | Li, Wencheng; Liu, Jiao; Hammond, Sean L; Tjalkens, Ronald B; Saifudeen, Zubaida; Feng, Yumei | R01ES021656 | Am J Physiol Regul Integr Comp Physiol (2015 Jul 15) |
25994957
|
2015 |
| Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glia ... | De Miranda, Briana R; Popichak, Katriana A; Hammond, Sean L; Miller, James A; Safe, Stephen; Tj ... | R01ES021656 | Toxicol Sci (2015 Feb) |
25406165
|
2015 |
| Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water an ... | Schilz, Jodi R; Reddy, K J; Nair, Sreejayan; Johnson, Thomas E; Tjalkens, Ronald B; Krueger, K ... | R01ES021656 | J Vis Exp (2015 Jun 21) |
26132311
|
2015 |
| The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expressio ... | De Miranda, Briana R; Popichak, Katriana A; Hammond, Sean L; Jorgensen, Bryce A; Phillips, Aaro ... | R01ES021656 | Mol Pharmacol (2015 Jun) |
25858541
|
2015 |
| Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells. | Lee, Syng-Ook; Li, Xi; Hedrick, Erik; Jin, Un-Ho; Tjalkens, Ronald B; Backos, Donald S; Li, L ... | R01ES021656 | Mol Endocrinol (2014 Oct) |
25099012
|
2014 |
| Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes. | Streifel, Karin M; Gonzales, Albert L; De Miranda, Briana; Mouneimne, Rola; Earley, Scott; Tjal ... | R01ES021656 | PLoS One (2014) |
25365260
|
2014 |
| Repeated exposure to low doses of kainic acid activates nuclear factor kappa B (NF-κB) prior to seiz ... | Miller, James A; Kirkley, Kelly A; Padmanabhan, Rachel; Liang, Li-Ping; Raol, Yogendra H; Patel ... | R01ES021656 | Neurotoxicology (2014 Sep) |
24813937
|
2014 |
| Manganese inhibits ATP-induced calcium entry through the transient receptor potential channel TRPC3 ... | Streifel, Karin M; Miller, James; Mouneimne, Rola; Tjalkens, Ronald B | R01ES021656 | Neurotoxicology (2013 Jan) |
23131343
|
2013 |
| Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substit ... | De Miranda, Briana R; Miller, James A; Hansen, Ryan J; Lunghofer, Paul J; Safe, Stephen; Gustaf ... | R01ES021656 | J Pharmacol Exp Ther (2013 Apr) |
23318470
|
2013 |