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Who We Fund: Publication Detail

Project Title: GENE X ENVIRONMENT INTERACTIONS IN THE PATHOGENESIS OF UTERINE FIBROIDS
PI: Al-Hendy, Ayman
Institution: University Of Chicago
Grant Number: R01ES028615

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 45 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.grantpubdetail&&grant_number=R01ES028615&format=excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Progesterone Signaling and Uterine Fibroid Pathogenesis; Molecular Mechanisms and Potential Therapeu ...   Ali, Mohamed; Ciebiera, Michał; Vafaei, Somayeh; Alkhrait, Samar; Chen, Hsin-Yuan; Chiang, Yi- ... R01ES028615 Cells (2023 Apr 09) 37190026 Exiting the NIEHS site 2023 
Quality of life with relugolix combination therapy for uterine fibroids: LIBERTY randomized trials.   Stewart, Elizabeth A; Lukes, Andrea S; Venturella, Roberta; Li, Yulan; Hunsche, Elke; Wagman, ... R01ES028615 Am J Obstet Gynecol (2023 Mar) 36370871 Exiting the NIEHS site 2023 
An evaluation of relugolix/estradiol/norethindrone acetate for the treatment of heavy menstrual blee ...   Ali, Mohamed; Chen, Hsin-Yuan; Chiang, Yi-Fen; Badary, Osama A; Hsia, Shih-Min; Al-Hendy, Ayma ... R01ES028615 Expert Opin Pharmacother (2022 Mar) 35068291 Exiting the NIEHS site 2022 
Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment.   Yang, Qiwei; Ciebiera, Michal; Bariani, Maria Victoria; Ali, Mohamed; Elkafas, Hoda; Boyer, Th ... R01ES028615 Endocr Rev (2022 Jul 13) 34741454 Exiting the NIEHS site 2022 
Corrigendum to: Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Tr ...   R01ES028615 Endocr Rev (2022 Jul 13) 35234847 Exiting the NIEHS site 2022 
Current approaches to overcome the side effects of GnRH analogs in the treatment of patients with ut ...   Ali, Mohamed; Raslan, Mohamed; Ciebiera, Michał; Zaręba, Kornelia; Al-Hendy, Ayman R01ES028615 Expert Opin Drug Saf (2022 Apr) 34612122 Exiting the NIEHS site 2022 
Developing RT-LAMP assays for rapid diagnosis of SARS-CoV-2 in saliva.   Huang, Xin; Tang, Gongyu; Ismail, Nahed; Wang, Xiaowei R01ES028615 EBioMedicine (2022 Jan) 34922321 Exiting the NIEHS site 2022 
Erratum to: Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatm ...   R01ES028615 Endocr Rev (2022 Jul 13) 35234873 Exiting the NIEHS site 2022 
Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.   Al-Hendy, Ayman; Lukes, Andrea S; Poindexter 3rd, Alfred N; Venturella, Roberta; Villarroel, Cl ... R01ES028615 Obstet Gynecol (2022 Dec 01) 36357960 Exiting the NIEHS site 2022 
The Functional Role and Regulatory Mechanism of Bromodomain-Containing Protein 9 in Human Uterine Le ...   Yang, Qiwei; Bariani, Maria Victoria; Falahati, Ali; Khosh, Azad; Lastra, Ricardo R; Siblini, ... R01ES028615 Cells (2022 Jul 10) 35883603 Exiting the NIEHS site 2022 
The Regulatory Functions and the Mechanisms of Long Non-Coding RNAs in Cervical Cancer.   Yang, Qiwei; Al-Hendy, Ayman R01ES028615 Cells (2022 Mar 29) 35406713 Exiting the NIEHS site 2022 
Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopau ...   Ali, Mohamed; A R, Sara; Al Hendy, Ayman R01ES028615 Expert Rev Clin Pharmacol (2021 Apr) 33682578 Exiting the NIEHS site 2021 
Endocrine-Disrupting Chemicals and Vitamin D Deficiency in the Pathogenesis of Uterine Fibroids.   Elkafas, Hoda; Badary, Osama; Elmorsy, Engy; Kamel, Rehab; Yang, Qiwei; Al-Hendy, Ayman R01ES028615 J Adv Pharm Res (2021) 34746367 Exiting the NIEHS site 2021 
Nutrition in Gynecological Diseases: Current Perspectives.   Ciebiera, Michał; Esfandyari, Sahar; Siblini, Hiba; Prince, Lillian; Elkafas, Hoda; Wojtyła, C ... R01ES028615 Nutrients (2021 Apr 02) 33918317 Exiting the NIEHS site 2021 
Predictors of response for elagolix with add-back therapy in women with heavy menstrual bleeding ass ...   Al-Hendy, Ayman; Bradley, Linda; Owens, Charlotte D; Wang, Hui; Barnhart, Kurt T; Feinberg, Ev ... R01ES028615 Am J Obstet Gynecol (2021 01) 32702363 Exiting the NIEHS site 2021 
The Role of Hedgehog Pathway in Uterine Leiomyosarcoma.   Garcia, Natalia; Ulin, Mara; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 J Cell Sci Ther (2021) 34956733 Exiting the NIEHS site 2021 
The Significance of Measuring Vitamin D Serum Levels in Women with Uterine Fibroids.   Ciebiera, Michał; Ali, Mohamed; Prince, Lillian; Zgliczyński, Stanisław; Jakiel, Grzegorz; Al-H ... R01ES028615 Reprod Sci (2021 08) 33108619 Exiting the NIEHS site 2021 
Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.   Al-Hendy, Ayman; Lukes, Andrea S; Poindexter 3rd, Alfred N; Venturella, Roberta; Villarroel, Cl ... R01ES028615 N Engl J Med (2021 02 18) 33596357 Exiting the NIEHS site 2021 
Activation of β-Catenin Signaling and its Crosstalk With Estrogen and Histone Deacetylases in Human ...   Ali, Mohamed; Shahin, Sara Mahmoud; Sabri, Nagwa Ali; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 J Clin Endocrinol Metab (2020 04 01) 31761932 Exiting the NIEHS site 2020 
Alcohol Consumption and Risk of Uterine Fibroids.   Takala, Hajra; Yang, Qiwei; El Razek, Ahmed M Abd; Ali, Mohamed; Al-Hendy, Ayman R01ES028615 Curr Mol Med (2020) 31612831 Exiting the NIEHS site 2020 
Elagolix Treatment for Up to 12 Months in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas ...   Simon, James A; Al-Hendy, Ayman; Archer, David F; Barnhart, Kurt T; Bradley, Linda D; Carr, Br ... R01ES028615 Obstet Gynecol (2020 06) 32459423 Exiting the NIEHS site 2020 
Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap!   Ali, Mohamed; Esfandyari, Sahar; Al-Hendy, Ayman R01ES028615 Fertil Steril (2020 06) 32482253 Exiting the NIEHS site 2020 
Mesenchymal Stem Cells as a Bio Organ for Treatment of Female Infertility.   Esfandyari, Sahar; Chugh, Rishi Man; Park, Hang-Soo; Hobeika, Elie; Ulin, Mara; Al-Hendy, Ayma ... R01ES028615 Cells (2020 10 08) 33050021 Exiting the NIEHS site 2020 
Molecular Bio-Imaging Probe for Non-Invasive Differentiation Between Human Leiomyoma Versus Leiomyos ...   Shalaby, Shahinaz; Khater, Mostafa; Laknaur, Archana; Arbab, Ali; Al-Hendy, Ayman R01ES028615 Reprod Sci (2020 02) 31925772 Exiting the NIEHS site 2020 
Non-hormonal mediators of uterine fibroid growth.   Cetin, Esra; Al-Hendy, Ayman; Ciebiera, Michał R01ES028615 Curr Opin Obstet Gynecol (2020 10) 32739973 Exiting the NIEHS site 2020 
The Evolving Role of Natural Compounds in the Medical Treatment of Uterine Fibroids.   Ciebiera, Michał; Ali, Mohamed; Prince, Lillian; Jackson-Bey, Tia; Atabiekov, Ihor; Zgliczyński ... R01ES028615 J Clin Med (2020 May 14) 32423112 Exiting the NIEHS site 2020 
The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis.   Bariani, Maria Victoria; Rangaswamy, Roshni; Siblini, Hiba; Yang, Qiwei; Al-Hendy, Ayman; Zota, ... R01ES028615 Curr Opin Endocrinol Diabetes Obes (2020 12) 33044243 Exiting the NIEHS site 2020 
The Role of Hedgehog Pathway in Female Cancers.   Garcia, Natalia; Ulin, Mara; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 J Cancer Sci Clin Ther (2020) 33179013 Exiting the NIEHS site 2020 
The Selective Progesterone Receptor Modulator Ulipristal Acetate Inhibits the Activity of the Glucoc ...   Small, Benjamin; Millard, Charles E F; Kisanga, Edwina P; Burman, Andreanna; Anam, Anika; Flann ... R01ES028615 J Clin Endocrinol Metab (2020 03 01) 31665442 Exiting the NIEHS site 2020 
Uterine fibroids in menopause and perimenopause.   Ulin, Mara; Ali, Mohamed; Chaudhry, Zunir Tayyeb; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 Menopause (2020 02) 31834160 Exiting the NIEHS site 2020 
Vitamin D and uterine fibroids: preclinical evidence is in; time for an overdue clinical study!   Ali, Mohamed; Prince, Lillian; Al-Hendy, Ayman R01ES028615 Fertil Steril (2020 01) 32033736 Exiting the NIEHS site 2020 
Vitamin D3 Ameliorates DNA Damage Caused by Developmental Exposure to Endocrine Disruptors in the Ut ...   Elkafas, Hoda; Ali, Mohamed; Elmorsy, Engy; Kamel, Rehab; Thompson, Winston E; Badary, Osama; ... R01ES028615 Cells (2020 06 12) 32545544 Exiting the NIEHS site 2020 
Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance.   Ciebiera, Michał; Ali, Mohamed; Zgliczyńska, Magdalena; Skrzypczak, Maciej; Al-Hendy, Ayman R01ES028615 Int J Mol Sci (2020 Aug 01) 32752274 Exiting the NIEHS site 2020 
1,25 Dihydroxyvitamin D3 Enhances the Antifibroid Effects of Ulipristal Acetate in Human Uterine Fib ...   Ali, Mohamed; Shahin, Sara Mahmoud; Sabri, Nagwa Ali; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 Reprod Sci (2019 06) 30514160 Exiting the NIEHS site 2019 
A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstra ...   Prusinski Fernung, Lauren E; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 Reprod Sci (2019 05) 29954254 Exiting the NIEHS site 2019 
Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Interventi ...   Igboeli, P; Walker, W; McHugh, A; Sultan, A; Al-Hendy, A R01ES028615 Curr Opin Gynecol Obstet (2019) 32647835 Exiting the NIEHS site 2019 
Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by ...   Ali, Mohamed; Shahin, Sara Mahmoud; Sabri, Nagwa Ali; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 Acta Pharmacol Sin (2019 Jul) 30478352 Exiting the NIEHS site 2019 
Myometrial progesterone hyper-responsiveness associated with increased risk of human uterine fibroid ...   Omar, Mona; Laknaur, Archana; Al-Hendy, Ayman; Yang, Qiwei R01ES028615 BMC Womens Health (2019 07 09) 31288815 Exiting the NIEHS site 2019 
Elagolix Alone or With Add-Back Therapy in Women With Heavy Menstrual Bleeding and Uterine Leiomyoma ...   Carr, Bruce R; Stewart, Elizabeth A; Archer, David F; Al-Hendy, Ayman; Bradley, Linda; Watts, ... R01ES028615 Obstet Gynecol (2018 11) 30303923 Exiting the NIEHS site 2018 
Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering ...   Prusinski Fernung, Lauren E; Yang, Qiwei; Sakamuro, Daitoku; Kumari, Alpana; Mas, Aymara; Al-He ... R01ES028615 Biol Reprod (2018 Oct 01) 29688260 Exiting the NIEHS site 2018 
Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Pa ...   Prusinski Fernung, Lauren E; Jones, Kimya; Mas, Aymara; Kleven, Daniel; Waller, Jennifer L; Al- ... R01ES028615 Am J Pathol (2018 10) 30075150 Exiting the NIEHS site 2018 
Successes and failures of uterine leiomyoma drug discovery.   Ali, Mohamed; Chaudhry, Zunir Tayyeb; Al-Hendy, Ayman R01ES028615 Expert Opin Drug Discov (2018 Feb) 29254389 Exiting the NIEHS site 2018 
The Emerging Role of p27 in Development of Diseases.   Yang, Qiwei; Al-Hendy, Ayman R01ES028615 Cancer Stud Mol Med (2018 Nov) 30474063 Exiting the NIEHS site 2018 
The emerging spectrum of early life exposure-related inflammation and epigenetic therapy.   Yang, Qiwei; Ali, Mohamed; El Andaloussi, Abdeljabar; Al-Hendy, Ayman R01ES028615 Cancer Stud Mol Med (2018 Nov) 30474062 Exiting the NIEHS site 2018 
The ontogeny of myometrial stem cells in OCT4-GFP transgenic mouse model.   Brakta, Soumia; Mas, Aymara; Al-Hendy, Ayman R01ES028615 Stem Cell Res Ther (2018 11 29) 30486855 Exiting the NIEHS site 2018 
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