Project Title: | AHR-MEDIATED IMMUNOSUPPRESSION IN GLIOBLASTOMA |
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PI: | Quintana, Francisco J. |
Institution: | Brigham And Women'S Hospital |
Grant Number: | R01ES029136 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells. | Sanmarco, Liliana M; Rone, Joseph M; Polonio, Carolina M; Fernandez Lahore, Gonzalo; Giovannoni, ... | R01ES029136 | Nature (2023 Aug) | 37558878 | 2023 |
Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting. | Charabati, Marc; Wheeler, Michael A; Weiner, Howard L; Quintana, Francisco J | R01ES029136 | Cell (2023 Mar 30) | 37001498 | 2023 |
The Ah Receptor from Toxicity to Therapeutics: Report from the 5th AHR Meeting at Penn State Univers ... | Perdew, Gary H; Esser, Charlotte; Snyder, Megan; Sherr, David H; van den Bogaard, Ellen H; McGo ... | R01ES029136, R01ES033692, R35ES028244 | Int J Mol Sci (2023 Mar 14) | 36982624 | 2023 |
Function and therapeutic value of astrocytes in neurological diseases. | Lee, Hong-Gyun; Wheeler, Michael A; Quintana, Francisco J | R01ES029136 | Nat Rev Drug Discov (2022 May) | 35173313 | 2022 |
AHR signaling is induced by infection with coronaviruses. | Giovannoni, Federico; Li, Zhaorong; Remes-Lenicov, Federico; Dávola, María E; Elizalde, Mercede ... | R01ES029136 | Nat Commun (2021 Aug 26) | 34446714 | 2021 |
Barcoded viral tracing of single-cell interactions in central nervous system inflammation. | Clark, Iain C; Gutiérrez-Vázquez, Cristina; Wheeler, Michael A; Li, Zhaorong; Rothhammer, Veit; ... | R01ES029136 | Science (2021 04 23) | 33888612 | 2021 |
Functional immune cell-astrocyte interactions. | Sanmarco, Liliana M; Polonio, Carolina M; Wheeler, Michael A; Quintana, Francisco J | R01ES029136 | J Exp Med (2021 09 06) | 34292315 | 2021 |
Glial and myeloid heterogeneity in the brain tumour microenvironment. | Andersen, Brian M; Faust Akl, Camilo; Wheeler, Michael A; Chiocca, E Antonio; Reardon, David A; ... | R01ES025530, R01ES029136 | Nat Rev Cancer (2021 Dec) | 34584243 | 2021 |
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. | Sanmarco, Liliana M; Wheeler, Michael A; Gutiérrez-Vázquez, Cristina; Polonio, Carolina Manganel ... | R01ES029136 | Nature (2021 Feb) | 33408417 | 2021 |
Microglia and Central Nervous System-Associated Macrophages-From Origin to Disease Modulation. | Prinz, Marco; Masuda, Takahiro; Wheeler, Michael A; Quintana, Francisco J | R01ES029136 | Annu Rev Immunol (2021 04 26) | 33556248 | 2021 |
Role of sphingolipid metabolism in neurodegeneration. | Alaamery, Manal; Albesher, Nour; Aljawini, Nora; Alsuwailm, Moneera; Massadeh, Salam; Wheeler, ... | R01ES025530, R01ES029136 | J Neurochem (2021 07) | 32402091 | 2021 |
The aryl hydrocarbon receptor suppresses immunity to oral squamous cell carcinoma through immune che ... | Kenison, Jessica E; Wang, Zhongyan; Yang, Kangkang; Snyder, Megan; Quintana, Francisco J; Sherr ... | R01ES029136 | Proc Natl Acad Sci U S A (2021 05 11) | 33941684 | 2021 |
TrbK controls astrocyte-driven oligodendrocyte copper poisoning. | Quintana, Francisco J; Weiner, Howard L | R01ES029136 | Proc Natl Acad Sci U S A (2021 08 10) | 34344829 | 2021 |
Astrocyte Crosstalk in CNS Inflammation. | Linnerbauer, Mathias; Wheeler, Michael A; Quintana, Francisco J | R01ES025530, R01ES029136 | Neuron (2020 11 25) | 32898475 | 2020 |
How the AHR Became Important in Cancer: The Role of Chronically Active AHR in Cancer Aggression. | Wang, Zhongyan; Snyder, Megan; Kenison, Jessica E; Yang, Kangkang; Lara, Brian; Lydell, Emily; ... | R01ES029136 | Int J Mol Sci (2020 Dec 31) | 33396563 | 2020 |
The Gut-CNS Axis in Multiple Sclerosis. | Kadowaki, Atsushi; Quintana, Francisco J | R01ES029136 | Trends Neurosci (2020 08) | 32650957 | 2020 |
The NLRP3 inflammasome in progressive multiple sclerosis. | Kadowaki, Atsushi; Quintana, Francisco J | R01ES029136 | Brain (2020 05 01) | 32438410 | 2020 |
Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS. | Chao, Chun-Cheih; Gutiérrez-Vázquez, Cristina; Rothhammer, Veit; Mayo, Lior; Wheeler, Michael A ... | R01ES025530, R01ES029136 | Cell (2019 12 12) | 31813625 | 2019 |