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Who We Fund: Publication Detail

Project Title: PCB-MEDIATED DYSBIOSIS OF THE GUT MICROBIOME: A MISSING LINK IN PCB-MEDIATED NEURODEVELOPMENTAL DISORDERS?
PI: Lehmler, Hans-Joachim
Institution: University Of Iowa
Grant Number: R01ES031098

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Viewing 21 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intrap ...   Bullert, Amanda; Li, Xueshu; Zhang, Chunyun; Lee, Kendra; Pulliam, Casey F; Cagle, Brianna S; ... P30ES005605, P42ES013661, R01ES014901, R01ES031098 bioRxiv (2023 Aug 09) 37609242 Exiting the NIEHS site 2023 
Disposition and metabolomic effects of 2,2',5,5'-tetrachlorobiphenyl in female rats following intrap ...   Bullert, Amanda; Li, Xueshu; Chunyun, Zhang; Lee, Kendra; Pulliam, Casey F; Cagle, Brianna S; ... P30ES005605, P42ES013661, R01ES014901, R01ES031098 Environ Toxicol Pharmacol (2023 Sep) 37572994 Exiting the NIEHS site 2023 
Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2',3,5',6-Pentachlo ...   Li, Xueshu; Bullert, Amanda J; Han, Weiguo; Yang, Weizhu; Zhang, Qing-Yu; Ding, Xinxin; Lehmle ... P30ES005605, P30ES006694, P42ES013661, R01ES014901, R01ES020867, R01ES031098 Chem Res Toxicol (2023 Aug 21) 37467352 Exiting the NIEHS site 2023 
Maternal PBDE exposure disrupts gut microbiome and promotes hepatic proinflammatory signaling in hum ...   Kim, Sarah; Li, Hao; Jin, Yan; Armad, Jasmine; Gu, Haiwei; Mani, Sridhar; Cui, Julia Y P30ES007033, R01ES030197, R01ES031098 Toxicol Sci (2023 Jul 28) 37267213 Exiting the NIEHS site 2023 
Rebuttal to Correspondence on "Machine Learning-Assisted Identification and Quantification of Hydrox ...   Zhang, Chun-Yun; Li, Xueshu; Keil Stietz, Kimberly P; Sethi, Sunjay; Yang, Weizhu; Marek, Rach ... P30ES005605, P30ES006694, P30ES023513, P42ES013661, R01ES014901, R01ES031098 Environ Sci Technol (2023 Apr 18) 37017328 Exiting the NIEHS site 2023 
Effect of Chronic Cadmium Exposure on Brain and Liver Transporters and Drug-Metabolizing Enzymes in ...   Wang, Hao; Zhang, Liang; Xia, Zhengui; Cui, Julia Yue P30ES007033, R01ES030197, R01ES031098 Drug Metab Dispos (2022 Oct) 35878927 Exiting the NIEHS site 2022 
Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlor ...   Zhang, Chun-Yun; Li, Xueshu; Keil Stietz, Kimberly P; Sethi, Sunjay; Yang, Weizhu; Marek, Rach ... P30ES005605, P30ES023513, P42ES013661, R01ES014901, R01ES031098 Environ Sci Technol (2022 Sep 20) 36047920 Exiting the NIEHS site 2022 
Metabolism of 3-Chlorobiphenyl (PCB 2) in a Human-Relevant Cell Line: Evidence of Dechlorinated Meta ...   Zhang, Chun-Yun; Li, Xueshu; Flor, Susanne; Ruiz, Patricia; Kruve, Anneli; Ludewig, Gabriele; ... P30ES005605, P42ES013661, R01ES014901, R01ES031098 Environ Sci Technol (2022 Sep 06) 35994059 Exiting the NIEHS site 2022 
Perfluorinated Carboxylic Acids with Increasing Carbon Chain Lengths Upregulate Amino Acid Transport ...   Lim, Joe Jongpyo; Suh, Youjun; Faustman, Elaine M; Cui, Julia Yue P30ES007033, R01ES030197, R01ES031098, T32ES007032 Drug Metab Dispos (2022 Oct) 34857530 Exiting the NIEHS site 2022 
Pregnane X Receptor and the Gut-Liver Axis: A Recent Update.   Dutta, Moumita; Lim, Joe Jongpyo; Cui, Julia Yue P30ES005605, R01ES030197, R01ES031098 Drug Metab Dispos (2022 Apr) 34862253 Exiting the NIEHS site 2022 
The disposition of polychlorinated biphenyls (PCBs) differs between germ-free and conventional mice.   Li, Xueshu; Lim, Joe Jongpyo; Wang, Kai; Prasad, Bhagwat; Bhatt, Deepak K; Cui, Julia Yue; Leh ... P30ES005605, P30ES007033, P42ES013661, R01ES014901, R01ES031098, T32ES007032 Environ Toxicol Pharmacol (2022 May) 35331926 Exiting the NIEHS site 2022 
Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and C ...   Little, Mallory; Dutta, Moumita; Li, Hao; Matson, Adam; Shi, Xiaojian; Mascarinas, Gabby; Moll ... P30ES007033, R01ES031098, R25ES025503 Acta Pharm Sin B (2022 Feb) 35256948 Exiting the NIEHS site 2022 
Cadmium exposure modulates the gut-liver axis in an Alzheimer's disease mouse model.   Zhang, Angela; Matsushita, Megumi; Zhang, Liang; Wang, Hao; Shi, Xiaojian; Gu, Haiwei; Xia, Z ... P30ES007033, R01ES030197, R01ES031098, T32ES007032, T32ES015459 Commun Biol (2021 Dec 15) 34912029 Exiting the NIEHS site 2021 
Characterization of the Metabolic Pathways of 4-Chlorobiphenyl (PCB3) in HepG2 Cells Using the Metab ...   Zhang, Chun-Yun; Flor, Susanne; Ruiz, Patricia; Ludewig, Gabriele; Lehmler, Hans-Joachim P30ES005605, P42ES013661, R01ES014901, R01ES031098 Environ Sci Technol (2021 07 06) 34125531 Exiting the NIEHS site 2021 
Disposition of PCB 11 in Mice Following Acute Oral Exposure.   Zhang, Chun-Yun; Klocke, Carolyn R; Lein, Pamela J; Lehmler, Hans-Joachim P30ES005605, P42ES013661, R01ES014901, R01ES029213, R01ES029213, R01ES031098 Chem Res Toxicol (2021 04 19) 33734669 Exiting the NIEHS site 2021 
Neonatal Exposure to BPA, BDE-99, and PCB Produces Persistent Changes in Hepatic Transcriptome Assoc ...   Lim, Joe Jongpyo; Dutta, Moumita; Dempsey, Joseph L; Lehmler, Hans-Joachim; MacDonald, James; B ... P30ES005605, P30ES007033, P30ES030285, R01ES030197, R01ES031098, T32ES007032 Toxicol Sci (2021 Oct 27) 34453844 Exiting the NIEHS site 2021 
Nontarget analysis reveals gut microbiome-dependent differences in the fecal PCB metabolite profiles ...   Li, Xueshu; Liu, Yanna; Martin, Jonathan W; Cui, Julia Yue; Lehmler, Hans-Joachim P30ES005605, P30ES007033, P42ES013661, R01ES014901, R01ES030197, R01ES031098 Environ Pollut (2021 Jan 01) 33032095 Exiting the NIEHS site 2021 
Pregnane X receptor exacerbates nonalcoholic fatty liver disease accompanied by obesity- and inflamm ...   Kim, Sarah; Choi, Sora; Dutta, Moumita; Asubonteng, Jeffrey O; Polunas, Marianne; Goedken, Mic ... P30ES005605, P30ES007033, R01ES030197, R01ES031098 Biochem Pharmacol (2021 Nov) 34303710 Exiting the NIEHS site 2021 
RNA-Seq unveiled section-specific host response to lack of gut microbiota in mouse intestine.   Fu, Zidong Donna; Selwyn, Felcy Pavithra; Cui, Julia Yue; Klaassen, Curtis D P30ES007033, R01ES031098 Toxicol Appl Pharmacol (2021 12 15) 34715074 Exiting the NIEHS site 2021 
Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorina ...   Li, Xueshu; Zhang, Chunyun; Wang, Kai; Lehmler, Hans-Joachim P30ES005605, P42ES013661, R01ES014901, R01ES031098 Environ Pollut (2020 Nov) 32712482 Exiting the NIEHS site 2020 
Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Tran ...   Lim, Joe Jongpyo; Li, Xueshu; Lehmler, Hans-Joachim; Wang, Dongfang; Gu, Haiwei; Cui, Julia Yu ... P30ES005605, P30ES007033, P42ES013661, R01ES030197, R01ES031098, T32ES007032 Toxicol Sci (2020 09 01) 32544245 Exiting the NIEHS site 2020 
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