| Project Title: | ACTIVATION OF THE AH RECEPTOR AND EPITHELIAL INTEGRITY |
|---|---|
| PI: | Perdew, Gary H. |
| Institution: | Pennsylvania State University, The |
| Grant Number: | R35ES028244 |
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Viewing 44 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and H ... | Tian, Yuan; Rimal, Bipin; Bisanz, Jordan E; Gui, Wei; Wolfe, Trenton M; Koo, Imhoi; Murray, I ... | R35ES028244, R35ES035027 | Environ Health Perspect (2024 Aug) |
39140734
|
2024 |
| Electrical Impedance Spectroscopy Quantifies Skin Barrier Function in Organotypic In Vitro Epidermis ... | van den Brink, N J M; Pardow, F; Meesters, L D; van Vlijmen-Willems, I; Rodijk-Olthuis, D; Nieh ... | R35ES028244 | bioRxiv (2024 Mar 19) |
38562885
|
2024 |
| Immune cell-intrinsic Ah receptor facilitates the expression of antimicrobial REG3G in the small int ... | Chakraborty, Debopriya; Coslo, Denise M; Murray, Iain A; Vijay, Anitha; Patterson, Andrew D; Pe ... | R35ES028244, R35ES035027 | FASEB J (2024 Feb 29) |
38358358
|
2024 |
| Modulation of Ceramide-Induced Apoptosis in Enteric Neurons by Aryl Hydrocarbon Receptor Signaling: ... | Anitha, Mallappa; Kumar, Supriya M; Koo, Imhoi; Perdew, Gary H; Srinivasan, Shanthi; Patterson, ... | R35ES028244, R35ES035027 | Int J Mol Sci (2024 Aug 06) |
39201268
|
2024 |
| Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activ ... | Yokoyama, Shigetoshi; Koo, Imhoi; Aibara, Daisuke; Tian, Yuan; Murray, Iain A; Collins, Stepha ... | R35ES028244, R35ES035027 | Adv Sci (Weinh) (2024 Oct) |
39207053
|
2024 |
| Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight jun ... | Ganapathy, Ashwinkumar Subramenium; Saha, Kushal; Wang, Alexandra; Arumugam, Priya; Dharmaprakas ... | R35ES028244 | Cell Rep (2023 Jul 25) |
37393618
|
2023 |
| Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the productio ... | Saha, Kushal; Subramenium Ganapathy, Ashwinkumar; Wang, Alexandra; Arumugam, Priya; Michael Morr ... | R35ES028244 | Mucosal Immunol (2023 Dec) |
37716509
|
2023 |
| Aryl hydrocarbon receptor activation affects nitrergic neuronal survival and delays intestinal motil ... | Vijay, Anitha; Boyle, Nina R; Kumar, Supriya M; Perdew, Gary H; Srinivasan, Shanthi; Patterson, ... | R35ES028244 | Toxicol Sci (2023 Mar 20) |
36782369
|
2023 |
| Aryl Hydrocarbon Receptor Activation Coordinates Mouse Small Intestinal Epithelial Cell Programming. | Zhou, Xiaoliang; Chakraborty, Debopriya; Murray, Iain A; Coslo, Denise; Kehs, Zoe; Vijay, Anit ... | R35ES028244 | Lab Invest (2023 Feb) |
37039146
|
2023 |
| Complex chemical signals dictate Ah receptor activation through the gut-lung axis. | Dong, Fangcong; Murray, Iain A; Annalora, Andrew; Coslo, Denise M; Desai, Dhimant; Gowda, Kris ... | R35ES028244 | FASEB J (2023 Jul) |
37272852
|
2023 |
| Contribution of Circulating Host and Microbial Tryptophan Metabolites Toward Ah Receptor Activation. | Morgan, Ethan W; Dong, Fangcong; Annalora, Andrew J; Murray, Iain A; Wolfe, Trenton; Erickson, ... | R35ES028244 | Int J Tryptophan Res (2023) |
37441265
|
2023 |
| Endogenous Tryptophan-Derived Ah Receptor Ligands are Dissociated from CYP1A1/1B1-Dependent Negative ... | Dong, Fangcong; Annalora, Andrew J; Murray, Iain A; Tian, Yuan; Marcus, Craig B; Patterson, An ... | R35ES028244 | Int J Tryptophan Res (2023) |
37434789
|
2023 |
| Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites. | Patel, Dhwani; Murray, Iain A; Dong, Fangcong; Annalora, Andrew J; Gowda, Krishne; Coslo, Deni ... | R35ES028244, R35ES035027 | Metabolites (2023 Aug 31) |
37755265
|
2023 |
| Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (Agaricu ... | Chen, Xiaoling; Patterson, Andrew D; Perdew, Gary H; Murray, Iain A; Kellogg, Joshua J | R35ES028244 | J Funct Foods (2023 Jul) |
37397272
|
2023 |
| Targeting Skin Barrier Function in Atopic Dermatitis. | van den Bogaard, Ellen H; Elias, Peter M; Goleva, Elena; Berdyshev, Evgeny; Smits, Jos P H; Dan ... | R35ES028244 | J Allergy Clin Immunol Pract (2023 May) |
36805053
|
2023 |
| The Ah Receptor from Toxicity to Therapeutics: Report from the 5th AHR Meeting at Penn State Univers ... | Perdew, Gary H; Esser, Charlotte; Snyder, Megan; Sherr, David H; van den Bogaard, Ellen H; McGo ... | R01ES029136, R01ES033692, R35ES028244 | Int J Mol Sci (2023 Mar 14) |
36982624
|
2023 |
| The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TF ... | Smits, Jos P H; Qu, Jieqiong; Pardow, Felicitas; van den Brink, Noa J M; Rodijk-Olthuis, Diana; ... | R35ES028244 | bioRxiv (2023 Jun 08) |
37333234
|
2023 |
| Third generation quinoline-3-carboxamide transcriptional disrupter of HDAC4, HIF-1α, and MEF-2 signa ... | Isaacs, John T; Dalrymple, Susan L; Antony, Lizamma; Marc Rosen, David; Coleman, Ilsa M; Nelson ... | R35ES028244 | Prostate (2023 Nov) |
37559436
|
2023 |
| AHR is a master regulator of diverse pathways in endogenous metabolism. | Granados, Jeffry C; Falah, Kian; Koo, Imhoi; Morgan, Ethan W; Perdew, Gary H; Patterson, Andre ... | R35ES028244 | Sci Rep (2022 Oct 05) |
36198709
|
2022 |
| Early Life Short-Term Exposure to Polychlorinated Biphenyl 126 in Mice Leads to Metabolic Dysfunctio ... | Tian, Yuan; Rimal, Bipin; Gui, Wei; Koo, Imhoi; Yokoyama, Shigetoshi; Perdew, Gary H; Patterso ... | R35ES028244 | Int J Mol Sci (2022 Jul 26) |
35897801
|
2022 |
| Gestational Insulin Resistance Is Mediated by the Gut Microbiome-Indoleamine 2,3-Dioxygenase Axis. | Priyadarshini, Medha; Navarro, Guadalupe; Reiman, Derek J; Sharma, Anukriti; Xu, Kai; Lednovich ... | R35ES028244 | Gastroenterology (2022 May) |
35032499
|
2022 |
| Multi-Omics Strategies for Investigating the Microbiome in Toxicology Research. | Morgan, Ethan W; Perdew, Gary H; Patterson, Andrew D | R35ES028244 | Toxicol Sci (2022 May 26) |
35285497
|
2022 |
| Interleukin-2-inducible T-cell kinase (Itk) signaling regulates potent noncanonical regulatory T cel ... | Mammadli, Mahinbanu; Harris, Rebecca; Suo, Liye; May, Adriana; Gentile, Teresa; Waickman, Adam ... | R35ES028244 | Clin Transl Med (2021 Dec) |
34919342
|
2021 |
| The aryl hydrocarbon receptor activates ceramide biosynthesis in mice contributing to hepatic lipoge ... | Liu, Qing; Zhang, Limin; Allman, Erik L; Hubbard, Troy D; Murray, Iain A; Hao, Fuhua; Tian, Y ... | R35ES028244 | Toxicology (2021 06 30) |
34097992
|
2021 |
| The aryl hydrocarbon receptor at the forefront of host-microbe interactions in the skin: A perspecti ... | van den Bogaard, Ellen H; Esser, Charlotte; Perdew, Gary H | R35ES028244 | Exp Dermatol (2021 10) |
34105853
|
2021 |
| The Enigma of AHR Activation in the Skin: Interplay among Ligands, Metabolism, and Bioavailability. | van den Bogaard, Ellen H; Perdew, Gary H | R35ES028244 | J Invest Dermatol (2021 06) |
34024340
|
2021 |
| How Ah Receptor Ligand Specificity Became Important in Understanding Its Physiological Function. | Murray, Iain A; Perdew, Gary H | R35ES028244 | Int J Mol Sci (2020 Dec 17) |
33348604
|
2020 |
| Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity. | Dong, Fangcong; Hao, Fuhua; Murray, Iain A; Smith, Philip B; Koo, Imhoi; Tindall, Alyssa M; Kr ... | R35ES028244 | Gut Microbes (2020 11 09) |
32783770
|
2020 |
| Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of ... | Muku, Gulsum E; Kusnadi, Ann; Kuzu, Guray; Tanos, Rachel; Murray, Iain A; Gowda, Krishne; Amin ... | R35ES028244 | Lab Invest (2020 Feb) |
31417158
|
2020 |
| Targeting Interleukin-2-Inducible T-Cell Kinase (ITK) Differentiates GVL and GVHD in Allo-HSCT. | Mammadli, Mahinbanu; Huang, Weishan; Harris, Rebecca; Sultana, Aisha; Cheng, Ying; Tong, Wei; ... | R35ES028244 | Front Immunol (2020) |
33324410
|
2020 |
| Targeting the pregnane X receptor using microbial metabolite mimicry. | Dvořák, Zdeněk; Kopp, Felix; Costello, Cait M; Kemp, Jazmin S; Li, Hao; Vrzalová, Aneta; Štěpá ... | P30ES007033, R01ES030197, R35ES028244 | EMBO Mol Med (2020 Apr 07) |
32153125
|
2020 |
| TCR Signal Strength and Antigen Affinity Regulate CD8+ Memory T Cells. | Solouki, Sabrina; Huang, Weishan; Elmore, Jessica; Limper, Candice; Huang, Fei; August, Avery | R35ES028244 | J Immunol (2020 09 01) |
32759295
|
2020 |
| The aryl hydrocarbon receptor as a mediator of host-microbiota interplay. | Dong, Fangcong; Perdew, Gary H | R35ES028244 | Gut Microbes (2020 11 09) |
33382356
|
2020 |
| Tuning T helper cell differentiation by ITK. | Elmore, Jessica P; McGee, Michael C; Nidetz, Natalie F; Anannya, Orchi; Huang, Weishan; August, ... | R35ES028244 | Biochem Soc Trans (2020 02 28) |
32049330
|
2020 |
| β-Naphthoflavone Activation of the Ah Receptor Alleviates Irradiation-Induced Intestinal Injury in M ... | Zhou, Xiaoliang; Li, Deguan; Xu, Wenqing; Zhang, Heng; Wang, Hao; Perdew, Gary H | R35ES028244 | Antioxidants (Basel) (2020 Dec 12) |
33322705
|
2020 |
| Isolation and Identification of Aryl Hydrocarbon Receptor Modulators in White Button Mushrooms (Agar ... | Tian, Yuan; Gui, Wei; Smith, Philip B; Koo, Imhoi; Murray, Iain A; Cantorna, Margherita T; Per ... | R35ES028244 | J Agric Food Chem (2019 Aug 21) |
31339733
|
2019 |
| Metatranscriptomic Analysis of the Mouse Gut Microbiome Response to the Persistent Organic Pollutant ... | Nichols, Robert G; Zhang, Jingtao; Cai, Jingwei; Murray, Iain A; Koo, Imhoi; Smith, Philip B; ... | R35ES028244 | Metabolites (2019 Dec 18) |
31861317
|
2019 |
| Microbiota Metabolism Promotes Synthesis of the Human Ah Receptor Agonist 2,8-Dihydroxyquinoline. | Hubbard, Troy D; Liu, Qing; Murray, Iain A; Dong, Fangcong; Miller 3rd, Charles; Smith, Philip ... | R35ES028244 | J Proteome Res (2019 04 05) |
30777439
|
2019 |
| Selective Ah Receptor Ligands Mediate Enhanced SREBP1 Proteolysis to Restrict Lipogenesis in Sebocyt ... | Muku, Gulsum E; Blazanin, Nicholas; Dong, Fangcong; Smith, Philip B; Thiboutot, Diane; Gowda, ... | R35ES028244 | Toxicol Sci (2019 Sep 01) |
31225620
|
2019 |
| Allelic variants of the aryl hydrocarbon receptor differentially influence UVB-mediated skin inflamm ... | Smith, Kayla J; Murray, Iain A; Boyer, Jacob A; Perdew, Gary H | R35ES028244 | Toxicology (2018 Feb 01) |
29197551
|
2018 |
| Metabolomics Reveals Aryl Hydrocarbon Receptor Activation Induces Liver and Mammary Gland Metabolic ... | Belton, Kerry R; Tian, Yuan; Zhang, Limin; Anitha, Mallappa; Smith, Philip B; Perdew, Gary H; ... | R35ES028244 | J Proteome Res (2018 Apr 06) |
29521512
|
2018 |
| Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report ... | Esser, Charlotte; Lawrence, B Paige; Sherr, David H; Perdew, Gary H; Puga, Alvaro; Barouki, Ro ... | P30ES001247, R35ES028244 | Int J Mol Sci (2018 Nov 15) |
30445691
|
2018 |
| Structural and Functional Analysis of the Gut Microbiome for Toxicologists. | Nichols, Robert G; Cai, Jingwei; Murray, Iain A; Koo, Imhoi; Smith, Philip B; Perdew, Gary H; ... | R35ES028244 | Curr Protoc Toxicol (2018 Nov) |
30230220
|
2018 |
| Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist. | Muku, Gulsum E; Murray, Iain A; Espín, Juan C; Perdew, Gary H | R35ES028244 | Metabolites (2018 Nov 29) |
30501068
|
2018 |