| Project Title: | NRF TRANSCRIPTION FACTORS IN ENVIRONMENTAL STRESS AND DISEASE INTERVENTION |
|---|---|
| PI: | Zhang, Donna D |
| Institution: | University Of Florida |
| Grant Number: | R35ES031575 |
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying ... | Liu, Pengfei; Anandhan, Annadurai; Chen, Jinjing; Shakya, Aryatara; Dodson, Matthew; Ooi, Aiks ... | P30ES006694, P42ES004940, R01ES031463, R35ES031575 | Redox Biol (2023 Feb) |
36495698
|
2023 |
| Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78. | Ambrose, Andrew J; Sivinski, Jared; Zerio, Christopher J; Zhu, Xiaoyi; Godek, Jack; Kumirov, V ... | R35ES031575 | J Med Chem (2023 Jan 12) |
36516003
|
2023 |
| Physachenolide C is a Potent, Selective BET Inhibitor. | Zerio, Christopher J; Sivinski, Jared; Wijeratne, E M Kithsiri; Xu, Ya-Ming; Ngo, Duc T; Ambros ... | R35ES031575 | J Med Chem (2023 Jan 12) |
36577036
|
2023 |
| The NRF2-p97-NRF2 negative feedback loop. | Shakya, Aryatara; Liu, Pengfei; Godek, Jack; McKee, Nicholas W; Dodson, Matthew; Anandhan, Ann ... | P30ES006694, R01ES031463, R35ES031575 | Redox Biol (2023 Sep) |
37573837
|
2023 |
| CHML is an NRF2 target gene that regulates mTOR function. | Dodson, Matthew; Dai, Wujing; Anandhan, Annadurai; Schmidlin, Cody J; Liu, Pengfei; Wilson, Na ... | P30ES006694, P42ES004940, R01ES031463, R35ES031575, T32ES007091 | Mol Oncol (2022 Apr) |
35184380
|
2022 |
| NRF2 and Diabetes: The Good, the Bad, and the Complex. | Dodson, Matthew; Shakya, Aryatara; Anandhan, Annadurai; Chen, Jinjing; Garcia, Joe G N; Zhang, ... | P42ES004940, R35ES031575 | Diabetes (2022 Dec 01) |
36409792
|
2022 |
| α-Syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal ... | A, Anandhan; W, Chen; N, Nguyen; L, Madhavan; M, Dodson; Zhang, D D | P42ES004940, R35ES031575 | Free Radic Biol Med (2022 Nov 01) |
36150560
|
2022 |
| FAM129B-dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells. | Schmidlin, Cody J; Tian, Wang; Dodson, Matthew; Chapman, Eli; Zhang, Donna D | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Mol Carcinog (2021 05) |
33684228
|
2021 |
| HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver d ... | Wei, Juncheng; Harada, Bryan T; Lu, Dan; Ma, Ruihua; Gao, Beixue; Xu, Yanan; Montauti, Elena; ... | R35ES031575 | Mol Cell (2021 Dec 16) |
34847358
|
2021 |
| Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism. | Liu, Pengfei; Dodson, Matthew; Li, Hui; Schmidlin, Cody J; Shakya, Aryatara; Wei, Yongyi; Garc ... | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Mol Metab (2021 09) |
33933676
|
2021 |
| NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexp ... | Anandhan, Annadurai; Nguyen, Nhat; Syal, Arjun; Dreher, Luke A; Dodson, Matthew; Zhang, Donna ... | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Aging Dis (2021 Jul) |
34221542
|
2021 |
| Targeting NRF2 to treat cancer. | Sivinski, Jared; Zhang, Donna D; Chapman, Eli | P30ES006694, R01ES031463, R35ES031575 | Semin Cancer Biol (2021 11) |
34102289
|
2021 |
| The intricacies of NRF2 regulation in cancer. | Schmidlin, Cody J; Shakya, Aryatara; Dodson, Matthew; Chapman, Eli; Zhang, Donna D | P30ES006694, P42ES004940, R01ES031463, R35ES031575, T32ES007091 | Semin Cancer Biol (2021 11) |
34020028
|
2021 |
| The NRF2-LOC344887 signaling axis suppresses pulmonary fibrosis. | Liu, Pengfei; Luo, Gang; Dodson, Matthew; Schmidlin, Cody J; Wei, Yongyi; Kerimoglu, Baris; Oo ... | P30ES006694, P42ES004940, R01ES031463, R35ES031575, T32ES007091 | Redox Biol (2021 01) |
33126057
|
2021 |
| Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis. | Anandhan, Annadurai; Dodson, Matthew; Schmidlin, Cody J; Liu, Pengfei; Zhang, Donna D | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Cell Chem Biol (2020 Apr 16) |
32275864
|
2020 |
| Chronic arsenic exposure enhances metastatic potential via NRF2-mediated upregulation of SOX9. | Schmidlin, Cody J; Zeng, Tao; Liu, Pengfei; Wei, Yongyi; Dodson, Matthew; Chapman, Eli; Zhang, ... | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Toxicol Appl Pharmacol (2020 Sep 01) |
32682831
|
2020 |
| Filtering through the role of NRF2 in kidney disease. | Schmidlin, Cody J; Dodson, Matthew B; Zhang, Donna D | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Arch Pharm Res (2020 Mar) |
31372933
|
2020 |
| Self-assembling prodrug nanotherapeutics for synergistic tumor targeted drug delivery. | Wang, Zhiren; Chen, Jiawei; Little, Nicholas; Lu, Jianqin | P30ES006694, R35ES031575 | Acta Biomater (2020 07 15) |
32454086
|
2020 |
| The role of natural products in revealing NRF2 function. | Zhang, Donna D; Chapman, Eli | P30ES006694, R35ES031575 | Nat Prod Rep (2020 Jun 01) |
32400766
|
2020 |
| Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates t ... | Kerins, Michael J; Liu, Pengfei; Tian, Wang; Mannheim, William; Zhang, Donna D; Ooi, Aikseng | P30ES006694, R35ES031575 | Mol Cell Biol (2019 Jul 01) |
31010806
|
2019 |
| Modulating NRF2 in Disease: Timing Is Everything. | Dodson, Matthew; de la Vega, Montserrat Rojo; Cholanians, Aram B; Schmidlin, Cody J; Chapman, E ... | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Annu Rev Pharmacol Toxicol (2019 Jan 06) |
30256716
|
2019 |
| Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation. | Liu, Pengfei; Tian, Wang; Tao, Shasha; Tillotson, Joseph; Wijeratne, E M Kithsiri; Gunatilaka, ... | R35ES031575, T32ES007091 | Cell Chem Biol (2019 Oct 17) |
31402317
|
2019 |
| NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis. | Dodson, Matthew; Castro-Portuguez, Raul; Zhang, Donna D | P30ES006694, P42ES004940, R35ES031575 | Redox Biol (2019 May) |
30692038
|
2019 |
| Redox regulation by NRF2 in aging and disease. | Schmidlin, Cody J; Dodson, Matthew B; Madhavan, Lalitha; Zhang, Donna D | P30ES006694, P42ES004940, R35ES031575, T32ES007091 | Free Radic Biol Med (2019 Apr) |
30654017
|
2019 |
| Spermidine Confers Liver Protection by Enhancing NRF2 Signaling Through a MAP1S-Mediated Noncanonica ... | Liu, Pengfei; de la Vega, Montserrat Rojo; Dodson, Matthew; Yue, Fei; Shi, Boyun; Fang, Deyu; ... | P30ES006694, P42ES004940, R35ES031575 | Hepatology (2019 Jul) |
30873635
|
2019 |