| Project Title: | TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGY |
|---|---|
| PI: | Guengerich, F Peter |
| Institution: | Vanderbilt University |
| Grant Number: | T32ES007028 |
These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Pathogenic bacteria experience pervasive RNA polymerase backtracking during infection. | Browning, Kaitlyn R; Merrikh, Houra | T32ES007028 | mBio (2024 Jan 16) |
38095872
|
2024 |
| A Paternal Fish Oil Diet Preconception Reduces Lung Inflammation in a Toxicant-Driven Murine Model o ... | Rumph, Jelonia T; Stephens, Victoria R; Ameli, Sharareh; Brown, LaKendria K; Rayford, Kayla J; ... | T32ES007028 | Mar Drugs (2023 Feb 27) |
36976210
|
2023 |
| Acute manganese exposure impairs glutamatergic function in a young mouse model of Alzheimer's diseas ... | Spitznagel, Brittany D; Buchanan, Rebecca A; Consoli, David C; Thibert, Megan K; Bowman, Aaron ... | R01ES031401, T32ES007028 | Neurotoxicology (2023 Mar) |
36621467
|
2023 |
| An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metaboli ... | Shelton, Catherine D; Sing, Elizabeth; Mo, Jessica; Shealy, Nicolas G; Yoo, Woongjae; Thomas, ... | T32ES007028 | Cell Host Microbe (2023 Oct 11) |
37794592
|
2023 |
| Ascorbate protects human kidney organoids from damage induced by cell-free hemoglobin. | Bejoy, Julie; Farry, Justin M; Qian, Eddie S; Dearing, Curtis H; Ware, Lorraine B; Bastarache, ... | T32ES007028 | Dis Model Mech (2023 Dec 01) |
37942584
|
2023 |
| Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infec ... | Spiga, Luisella; Fansler, Ryan T; Perera, Yasiru R; Shealy, Nicolas G; Munneke, Matthew J; Davi ... | T32ES007028 | Cell Host Microbe (2023 Oct 11) |
37776864
|
2023 |
| MALDI IMS-Derived Molecular Contour Maps: Augmenting Histology Whole-Slide Images. | Sharman, Kavya; Patterson, Nathan Heath; Migas, Lukasz G; Neumann, Elizabeth K; Allen, Jamie; G ... | T32ES007028 | J Am Soc Mass Spectrom (2023 May 03) |
37061946
|
2023 |
| Moving metals: How microbes deliver metal cofactors to metalloproteins. | Kunkle, Dillon E; Skaar, Eric P | T32ES007028 | Mol Microbiol (2023 Oct) |
37408317
|
2023 |
| Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging. | Quardokus, Ellen M; Saunders, Diane C; McDonough, Elizabeth; Hickey, John W; Werlein, Christoph ... | T32ES007028 | Nat Methods (2023 Aug) |
37468619
|
2023 |
| Pathogenic bacteria experience pervasive RNA polymerase backtracking during infection. | Browning, Kaitlyn R; Merrikh, Houra | T32ES007028 | bioRxiv (2023 May 12) |
37215019
|
2023 |
| Rapid Multivariate Analysis Approach to Explore Differential Spatial Protein Profiles in Tissue. | Sharman, Kavya; Patterson, Nathan Heath; Weiss, Andy; Neumann, Elizabeth K; Guiberson, Emma R; ... | T32ES007028 | J Proteome Res (2023 May 05) |
35849531
|
2023 |
| RTEL1 and MCM10 overcome topological stress during vertebrate replication termination. | Campos, Lillian V; Van Ravenstein, Sabrina X; Vontalge, Emma J; Greer, Briana H; Heintzman, Dar ... | T32ES007028 | Cell Rep (2023 Feb 28) |
36807139
|
2023 |
| A Paternal Fish Oil Diet Preconception Modulates the Gut Microbiome and Attenuates Necrotizing Enter ... | Rumph, Jelonia T; Stephens, Victoria R; Ameli, Sharareh; Gaines, Philip N; Osteen, Kevin G; Bru ... | T32ES007028 | Mar Drugs (2022 Jun 13) |
35736193
|
2022 |
| A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response. | Held, James P; Feng, Gaomin; Saunders, Benjamin R; Pereira, Claudia V; Burkewitz, Kristopher; P ... | T32ES007028 | Elife (2022 Apr 22) |
35451962
|
2022 |
| An RNA-binding protein acts as a major post-transcriptional modulator in Bacillus anthracis. | Pi, Hualiang; Weiss, Andy; Laut, Clare L; Grunenwald, Caroline M; Lin, Hannah K; Yi, Xinjie I; ... | T32ES007028 | Nat Commun (2022 Mar 21) |
35314695
|
2022 |
| Base excision repair system targeting DNA adducts of trioxacarcin/LL-D49194 antibiotics for self-res ... | Chen, Xiaorong; Bradley, Noah P; Lu, Wei; Wahl, Katherine L; Zhang, Mei; Yuan, Hua; Hou, Xian ... | T32ES007028 | Nucleic Acids Res (2022 Mar 21) |
35191495
|
2022 |
| DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis. | Laut, Clare L; Leasure, Catherine S; Pi, Hualiang; Carlin, Sophia M; Chu, Michelle L; Hillebran ... | T32ES007028 | Infect Immun (2022 01 25) |
34748369
|
2022 |
| High Spatial Resolution MALDI Imaging Mass Spectrometry of Fresh-Frozen Bone. | Good, Christopher J; Neumann, Elizabeth K; Butrico, Casey E; Cassat, James E; Caprioli, Richard ... | T32ES007028 | Anal Chem (2022 Feb 22) |
35138834
|
2022 |
| Highly multiplexed immunofluorescence of the human kidney using co-detection by indexing. | Neumann, Elizabeth K; Patterson, Nathan Heath; Rivera, Emilio S; Allen, Jamie L; Brewer, Maya; ... | T32ES007028 | Kidney Int (2022 Jan) |
34619231
|
2022 |
| Highly multiplexed, label-free proteoform imaging of tissues by individual ion mass spectrometry. | Su, Pei; McGee, John P; Durbin, Kenneth R; Hollas, Michael A R; Yang, Manxi; Neumann, Elizabet ... | T32ES007028 | Sci Adv (2022 Aug 12) |
35947651
|
2022 |
| Host Polyunsaturated Fatty Acids Potentiate Aminoglycoside Killing of Staphylococcus aureus. | Beavers, William N; Munneke, Matthew J; Stackhouse, Alex R; Freiberg, Jeffrey A; Skaar, Eric P | T32ES007028 | Microbiol Spectr (2022 Apr 27) |
35377191
|
2022 |
| Plant organellar genomes utilize gene conversion to drive heteroplasmic sorting. | Schaffner, Samantha H; Patel, Maulik R | T32ES007028 | Proc Natl Acad Sci U S A (2022 Sep 13) |
36044538
|
2022 |
| Referenced Kendrick Mass Defect Annotation and Class-Based Filtering of Imaging MS Lipidomics Experi ... | Richardson, Luke T; Neumann, Elizabeth K; Caprioli, Richard M; Spraggins, Jeffrey M; Solouki, T ... | T32ES007028 | Anal Chem (2022 Apr 12) |
35344335
|
2022 |
| Resistance-Guided Mining of Bacterial Genotoxins Defines a Family of DNA Glycosylases. | Bradley, Noah P; Wahl, Katherine L; Steenwyk, Jacob L; Rokas, Antonis; Eichman, Brandt F | T32ES007028 | mBio (2022 Apr 26) |
35311535
|
2022 |
| Revving an Engine of Human Metabolism: Activity Enhancement of Triosephosphate Isomerase via Hemi-Ph ... | Schachner, Luis F; Soye, Benjamin Des; Ro, Soo; Kenney, Grace E; Ives, Ashley N; Su, Taojunfen ... | T32ES007028 | ACS Chem Biol (2022 Oct 21) |
35951581
|
2022 |
| Salmonella enterica serovar Typhimurium uses anaerobic respiration to overcome propionate-mediated c ... | Shelton, Catherine D; Yoo, Woongjae; Shealy, Nicolas G; Torres, Teresa P; Zieba, Jacob K; Calcu ... | T32ES007028 | Cell Rep (2022 Jan 04) |
34986344
|
2022 |
| Screening transcriptional connections in Staphylococcus aureus using high-throughput transduction of ... | Weiss, Andy; Jackson, Jessica K; Shaw, Lindsey N; Skaar, Eric P | T32ES007028 | Microbiology (Reading) (2022 Apr) |
35446249
|
2022 |
| Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-ba ... | Hickey, John W; Neumann, Elizabeth K; Radtke, Andrea J; Camarillo, Jeannie M; Beuschel, Rebecca ... | T32ES007028 | Nat Methods (2022 Mar) |
34811556
|
2022 |
| Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis. | Weiss, Andy; Murdoch, Caitlin C; Edmonds, Katherine A; Jordan, Matthew R; Monteith, Andrew J; P ... | T32ES007028 | Cell (2022 Jun 09) |
35584702
|
2022 |
| A bistable, multiport valve enables microformulators creating microclinical analyzers that reveal ab ... | Miller, Dusty R; Schaffer, David K; Neely, M Diana; McClain, Ethan S; Travis, Adam R; Block 3rd ... | R01ES007331, R01ES010563, T32ES007028 | Sens Actuators B Chem (2021 Aug 15) |
34092923
|
2021 |
| A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors. | Kozlyuk, Natalia; Gilston, Benjamin A; Salay, Lauren E; Gogliotti, Rocco D; Christov, Plamen P; ... | T32ES007028 | Proteins (2021 11) |
34156100
|
2021 |
| A Preconception Paternal Fish Oil Diet Prevents Toxicant-Driven New Bronchopulmonary Dysplasia in Ne ... | Rumph, Jelonia T; Rayford, Kayla J; Stephens, Victoria R; Ameli, Sharareh; Nde, Pius N; Osteen, ... | T32ES007028 | Toxics (2021 Dec 27) |
35051049
|
2021 |
| Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice. | Wilcox, J M; Consoli, D C; Tienda, A A; Dixit, S; Buchanan, R A; May, J M; Nobis, W P; Harris ... | T32ES007028 | Neurobiol Dis (2021 10) |
34450329
|
2021 |
| Cellular retinoid-binding proteins transfer retinoids to human cytochrome P450 27C1 for desaturation ... | Glass, Sarah M; Guengerich, F Peter | T32ES007028 | J Biol Chem (2021 10) |
34480899
|
2021 |
| Characterization of human adrenal cytochrome P450 11B2 products of progesterone and androstenedione ... | Glass, Sarah M; Reddish, Michael J; Child, Stella A; Wilkey, Clayton J; Stec, Donald F; Guenger ... | T32ES007028 | J Steroid Biochem Mol Biol (2021 04) |
33189850
|
2021 |
| Clostridioides difficile strain-dependent and strain-independent adaptations to a microaerobic envir ... | Weiss, Andy; Lopez, Christopher A; Beavers, William N; Rodriguez, Jhoana; Skaar, Eric P | T32ES007028 | Microb Genom (2021 Dec) |
34908523
|
2021 |
| Colonization resistance: metabolic warfare as a strategy against pathogenic Enterobacteriaceae. | Shealy, Nicolas G; Yoo, Woongjae; Byndloss, Mariana X | T32ES007028 | Curr Opin Microbiol (2021 Dec) |
34688039
|
2021 |
| High-fat diet-induced colonocyte dysfunction escalates microbiota-derived trimethylamine N-oxide. | Yoo, Woongjae; Zieba, Jacob K; Foegeding, Nora J; Torres, Teresa P; Shelton, Catherine D; Sheal ... | T32ES007028 | Science (2021 08 13) |
34385401
|
2021 |
| Identification of Three Small Molecules That Can Selectively Influence Cellular Manganese Levels in ... | Horning, Kyle J; Tang, Xueqi; Thomas, Morgan G; Aschner, Michael; Bowman, Aaron B | R01ES010563, T32ES007028 | Molecules (2021 Feb 22) |
33671818
|
2021 |
| Mfd regulates RNA polymerase association with hard-to-transcribe regions in vivo, especially those w ... | Ragheb, Mark N; Merrikh, Christopher; Browning, Kaitlyn; Merrikh, Houra | T32ES007028 | Proc Natl Acad Sci U S A (2021 01 05) |
33443179
|
2021 |
| Protocol for multimodal analysis of human kidney tissue by imaging mass spectrometry and CODEX multi ... | Neumann, Elizabeth K; Patterson, Nathan Heath; Allen, Jamie L; Migas, Lukasz G; Yang, Haichun; ... | T32ES007028 | STAR Protoc (2021 Sep 17) |
34430920
|
2021 |
| Rapid prototyping of cell culture microdevices using parylene-coated 3D prints. | O'Grady, Brian J; Geuy, Michael D; Kim, Hyosung; Balotin, Kylie M; Allchin, Everett R; Florian, ... | T32ES007028 | Lab Chip (2021 Dec 07) |
34787148
|
2021 |
| Spatially Targeted Proteomics of the Host-Pathogen Interface during Staphylococcal Abscess Formation ... | Guiberson, Emma R; Weiss, Andy; Ryan, Daniel J; Monteith, Andrew J; Sharman, Kavya; Gutierrez, ... | T32ES007028 | ACS Infect Dis (2021 01 08) |
33270421
|
2021 |
| YAC128 mouse model of Huntington disease is protected against subtle chronic manganese (Mn)-induced ... | Wilcox, Jordyn M; Pfalzer, Anna C; Tienda, Adriana A; Debbiche, Ines F; Cox, Ellen C; Totten, ... | R01ES031401, T32ES007028 | Neurotoxicology (2021 Dec) |
34543681
|
2021 |
| A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens. | Juttukonda, Lillian J; Beavers, William N; Unsihuay, Daisy; Kim, Kwangho; Pishchany, Gleb; Horn ... | R01ES010563, T32ES007028 | mBio (2020 10 27) |
33109764
|
2020 |
| Bacillus anthracis Responds to Targocil-Induced Envelope Damage through EdsRS Activation of Cardioli ... | Laut, Clare L; Perry, William J; Metzger, Alexander L; Weiss, Andy; Stauff, Devin L; Walker, S ... | T32ES007028 | mBio (2020 03 31) |
32234818
|
2020 |
| Development of an N-Cadherin Biofunctionalized Hydrogel to Support the Formation of Synaptically Con ... | O'Grady, Brian J; Balotin, Kylie M; Bosworth, Allison M; McClatchey, P Mason; Weinstein, Robert ... | T32ES007028 | ACS Biomater Sci Eng (2020 Oct 12) |
33320550
|
2020 |
| Developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure of either parent enhances the risk of nec ... | Mokshagundam, Shilpa; Ding, Tianbing; Rumph, Jelonia T; Dallas, Madison; Stephens, Victoria R; ... | T32ES007028 | Birth Defects Res (2020 10) |
32519502
|
2020 |
| Environmental Endocrine Disruptors and Endometriosis. | Rumph, Jelonia T; Stephens, Victoria R; Archibong, Anthony E; Osteen, Kevin G; Bruner-Tran, Kay ... | T32ES007028 | Adv Anat Embryol Cell Biol (2020) |
33278007
|
2020 |
| Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks. | Bradley, Noah P; Washburn, Lauren A; Christov, Plamen P; Watanabe, Coran M H; Eichman, Brandt F | T32ES007028 | Nucleic Acids Res (2020 07 27) |
32409837
|
2020 |
| Functional interactions of adrenodoxin with several human mitochondrial cytochrome P450 enzymes. | Child, Stella A; Reddish, Michael J; Glass, Sarah M; Goldfarb, Margo H; Barckhausen, Ian R; Gue ... | T32ES007028 | Arch Biochem Biophys (2020 11 15) |
32980349
|
2020 |
| Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and m ... | Pfalzer, Anna C; Wilcox, Jordyn M; Codreanu, Simona G; Totten, Melissa; Bichell, Terry J V; Hal ... | R01ES010563, T32ES007028 | Metallomics (2020 Jul 22) |
32421118
|
2020 |
| Identification of a selective manganese ionophore that enables nonlethal quantification of cellular ... | Horning, Kyle J; Joshi, Piyush; Nitin, Rachana; Balachandran, Rekha C; Yanko, Frank M; Kim, Kw ... | R01ES010563, T32ES007028 | J Biol Chem (2020 Mar 20) |
32047113
|
2020 |
| Integrating ion mobility and imaging mass spectrometry for comprehensive analysis of biological tiss ... | Rivera, Emilio S; Djambazova, Katerina V; Neumann, Elizabeth K; Caprioli, Richard M; Spraggins, ... | T32ES007028 | J Mass Spectrom (2020 Dec) |
32955134
|
2020 |
| Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntin ... | Bryan, Miles R; Nordham, Kristen D; Rose, Daniel I R; O'Brien, Michael T; Joshi, Piyush; Foshag ... | R01ES010563, T32ES007028 | Mol Neurobiol (2020 Mar) |
31797328
|
2020 |
| Multimodal Imaging Mass Spectrometry: Next Generation Molecular Mapping in Biology and Medicine. | Neumann, Elizabeth K; Djambazova, Katerina V; Caprioli, Richard M; Spraggins, Jeffrey M | T32ES007028 | J Am Soc Mass Spectrom (2020 Dec 02) |
32886506
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2020 |
| Resolving the Complexity of Spatial Lipidomics Using MALDI TIMS Imaging Mass Spectrometry. | Djambazova, Katerina V; Klein, Dustin R; Migas, Lukasz G; Neumann, Elizabeth K; Rivera, Emilio ... | T32ES007028 | Anal Chem (2020 10 06) |
32808523
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2020 |
| The Microbiome and the Gut-Liver-Brain Axis for Central Nervous System Clinical Pharmacology: Challe ... | Hawkins, Kyle G; Casolaro, Caleb; Brown, Jacquelyn A; Edwards, David A; Wikswo, John P | T32ES007028 | Clin Pharmacol Ther (2020 11) |
32347548
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2020 |
| A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cel ... | Neal, Emma H; Marinelli, Nicholas A; Shi, Yajuan; McClatchey, P Mason; Balotin, Kylie M; Gullet ... | T32ES007028 | Stem Cell Reports (2019 06 11) |
31189096
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2019 |
| Acinetobacter baumannii OxyR Regulates the Transcriptional Response to Hydrogen Peroxide. | Juttukonda, Lillian J; Green, Erin R; Lonergan, Zachery R; Heffern, Marie C; Chang, Christopher ... | T32ES007028 | Infect Immun (2019 Jan) |
30297527
|
2019 |
| Acute manganese treatment restores defective autophagic cargo loading in Huntington's disease cell l ... | Bryan, Miles R; O'Brien, Michael T; Nordham, Kristen D; Rose, Daniel I R; Foshage, Audra M; Jos ... | R01ES010563, T32ES007028 | Hum Mol Genet (2019 11 15) |
31600787
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2019 |
| Common motifs in ETAA1 and TOPBP1 required for ATR kinase activation. | Thada, Vaughn; Cortez, David | T32ES007028 | J Biol Chem (2019 05 24) |
30940728
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2019 |
| Conformational selection dominates binding of steroids to human cytochrome P450 17A1. | Guengerich, F Peter; Wilkey, Clayton J; Glass, Sarah M; Reddish, Michael J | T32ES007028 | J Biol Chem (2019 06 28) |
31072872
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2019 |
| Emerging Roles of DNA Glycosylases and the Base Excision Repair Pathway. | Mullins, Elwood A; Rodriguez, Alyssa A; Bradley, Noah P; Eichman, Brandt F | T32ES007028 | Trends Biochem Sci (2019 09) |
31078398
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2019 |
| Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts. | Steenwyk, Jacob L; Opulente, Dana A; Kominek, Jacek; Shen, Xing-Xing; Zhou, Xiaofan; Labella, ... | T32ES007028 | PLoS Biol (2019 05) |
31112549
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2019 |
| Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochr ... | Albertolle, Matthew E; Song, Hyun D; Wilkey, Clayton J; Segrest, Jere P; Guengerich, F Peter | T32ES007028 | Chem Res Toxicol (2019 Mar 18) |
30701961
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2019 |
| High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spe ... | Spraggins, Jeffrey M; Djambazova, Katerina V; Rivera, Emilio S; Migas, Lukasz G; Neumann, Eliza ... | T32ES007028 | Anal Chem (2019 Nov 19) |
31593446
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2019 |
| Human cytochrome P450 11B2 produces aldosterone by a processive mechanism due to the lactol form of ... | Reddish, Michael J; Guengerich, F Peter | T32ES007028 | J Biol Chem (2019 08 30) |
31296661
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2019 |
| Isotopic tagging of oxidized and reduced cysteines (iTORC) for detecting and quantifying sulfenic ac ... | Albertolle, Matthew E; Glass, Sarah M; Trefts, Elijah; Guengerich, F Peter | T32ES007028 | J Biol Chem (2019 04 19) |
30850396
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2019 |
| Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling. | Wepy, James A; Galligan, James J; Kingsley, Philip J; Xu, Shu; Goodman, Michael C; Tallman, Ke ... | T32ES007028 | J Lipid Res (2019 02) |
30482805
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2019 |
| Nutrient Zinc at the Host-Pathogen Interface. | Lonergan, Zachery R; Skaar, Eric P | T32ES007028 | Trends Biochem Sci (2019 12) |
31326221
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2019 |
| Remodeling of mitochondrial morphology and function: an emerging hallmark of cellular reprogramming. | Rastogi, Anuj; Joshi, Piyush; Contreras, Ela; Gama, Vivian | T32ES007028 | Cell Stress (2019 May 27) |
31225513
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2019 |
| Striatal Cholesterol Precursors Are Altered with Age in Female Huntington's Disease Model Mice. | Pfalzer, Anna C; Wages, Phillip A; Porter, Ned A; Bowman, Aaron B | T32ES007028 | J Huntingtons Dis (2019) |
30958310
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2019 |
| Synthesis and Characterization of Site-Specific O6 -Alkylguanine DNA-Alkyl Transferase-Oligonucleoti ... | Ghodke, Pratibha P; Albertolle, Matthew E; Johnson, Kevin M; Guengerich, F Peter | T32ES007028 | Curr Protoc Nucleic Acid Chem (2019 03) |
30657645
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2019 |
| The abundant DNA adduct N7-methyl deoxyguanosine contributes to miscoding during replication by huma ... | Njuma, Olive J; Su, Yan; Guengerich, F Peter | T32ES007028 | J Biol Chem (2019 06 28) |
31101656
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2019 |
| Configurational and Conformational Equilibria of N6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3 ... | Bamberger, Stephanie N; Malik, Chanchal K; Voehler, Markus W; Brown, Summer K; Pan, Hope; Johns ... | R01ES029357, T32ES007028 | Chem Res Toxicol (2018 09 17) |
30169026
|
2018 |
| Inherent steroid 17α,20-lyase activity in defunct cytochrome P450 17A enzymes. | Gonzalez, Eric; Johnson, Kevin M; Pallan, Pradeep S; Phan, Thanh T N; Zhang, Wei; Lei, Li; Waw ... | T32ES007028 | J Biol Chem (2018 01 12) |
29212707
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2018 |
| Movement of the RecG Motor Domain upon DNA Binding Is Required for Efficient Fork Reversal. | Warren, Garrett M; Stein, Richard A; Mchaourab, Hassane S; Eichman, Brandt F | T32ES007028 | Int J Mol Sci (2018 Oct 06) |
30301235
|
2018 |
| Role of Calprotectin in Withholding Zinc and Copper from Candida albicans. | Besold, Angelique N; Gilston, Benjamin A; Radin, Jana N; Ramsoomair, Christian; Culbertson, Edw ... | T32ES007028, T32ES007141 | Infect Immun (2018 02) |
29133349
|
2018 |
| Selective base excision repair of DNA damage by the non-base-flipping DNA glycosylase AlkC. | Shi, Rongxin; Mullins, Elwood A; Shen, Xing-Xing; Lay, Kori T; Yuen, Philip K; David, Sheila S ... | T32ES007028 | EMBO J (2018 01 04) |
29054852
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2018 |
| Sulfenylation of Human Liver and Kidney Microsomal Cytochromes P450 and Other Drug-Metabolizing Enzy ... | Albertolle, Matthew E; Phan, Thanh T N; Pozzi, Ambra; Guengerich, F Peter | T32ES007028 | Mol Cell Proteomics (2018 05) |
29374135
|
2018 |
| The relationships between cytochromes P450 and H2O2: Production, reaction, and inhibition. | Albertolle, Matthew E; Peter Guengerich, F | T32ES007028 | J Inorg Biochem (2018 Sep) |
29990746
|
2018 |
| Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Even ... | Prentice, Boone M; Chumbley, Chad W; Caprioli, Richard M | T32ES007028 | J Am Soc Mass Spectrom (2017 01) |
27655354
|
2017 |
| Antibacterial photosensitization through activation of coproporphyrinogen oxidase. | Surdel, Matthew C; Horvath Jr, Dennis J; Lojek, Lisa J; Fullen, Audra R; Simpson, Jocelyn; Dutt ... | T32ES007028 | Proc Natl Acad Sci U S A (2017 Aug 08) |
28739897
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2017 |
| Compartmentalized Culture of Perivascular Stroma and Endothelial Cells in a Microfluidic Model of th ... | Gnecco, Juan S; Pensabene, Virginia; Li, David J; Ding, Tianbing; Hui, Elliot E; Bruner-Tran, ... | T32ES007028 | Ann Biomed Eng (2017 Jul) |
28108942
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2017 |
| Detecting Protein Sulfenylation in Cells Exposed to a Toxicant. | Wages, Phillip A | R01ES007331, T32ES007028 | Curr Protoc Toxicol (2017 Feb 01) |
28146279
|
2017 |
| Dietary Manganese Promotes Staphylococcal Infection of the Heart. | Juttukonda, Lillian J; Berends, Evelien T M; Zackular, Joseph P; Moore, Jessica L; Stier, Matth ... | T32ES007028 | Cell Host Microbe (2017 Oct 11) |
28943329
|
2017 |
| Exposure to the environmental endocrine disruptor TCDD and human reproductive dysfunction: Translati ... | Bruner-Tran, Kaylon L; Gnecco, Juan; Ding, Tianbing; Glore, Dana R; Pensabene, Virginia; Osteen ... | T32ES007028 | Reprod Toxicol (2017 Mar) |
27423904
|
2017 |
| Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic ... | Albertolle, Matthew E; Kim, Donghak; Nagy, Leslie D; Yun, Chul-Ho; Pozzi, Ambra; Savas, Üzen; ... | T32ES007028 | J Biol Chem (2017 07 07) |
28533430
|
2017 |
| Human mitochondrial cytochrome P450 27C1 is localized in skin and preferentially desaturates trans-r ... | Johnson, Kevin M; Phan, Thanh T N; Albertolle, Matthew E; Guengerich, F Peter | T32ES007028 | J Biol Chem (2017 08 18) |
28701464
|
2017 |
| In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter bauma ... | Aron, Allegra T; Heffern, Marie C; Lonergan, Zachery R; Vander Wal, Mark N; Blank, Brian R; Spa ... | T32ES007028 | Proc Natl Acad Sci U S A (2017 Nov 28) |
29138321
|
2017 |
| Instrumenting a Fetal Membrane on a Chip as Emerging Technology for Preterm Birth Research. | Gnecco, Juan S; Anders, Anjali P; Cliffel, David; Pensabene, Virginia; Rogers, Lisa M; Osteen, ... | T32ES007028 | Curr Pharm Des (2017) |
28847303
|
2017 |
| Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by hum ... | Gonzalez, Eric; Guengerich, F Peter | T32ES007028 | J Biol Chem (2017 08 11) |
28684414
|
2017 |
| Multianalyte Physiological Microanalytical Devices. | Davis, Anna Nix; Travis, Adam R; Miller, Dusty R; Cliffel, David E | T32ES007028 | Annu Rev Anal Chem (Palo Alto Calif) (2017 06 12) |
28605606
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2017 |
| Quantitative Analysis and Discovery of Lysine and Arginine Modifications. | Galligan, James J; Kingsley, Philip J; Wauchope, Orrette R; Mitchener, Michelle M; Camarillo, J ... | T32ES007028 | Anal Chem (2017 01 17) |
27982582
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2017 |
| Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse mo ... | Bichell, Terry Jo V; Wegrzynowicz, Michal; Tipps, K Grace; Bradley, Emma M; Uhouse, Michael A; ... | R01ES010563, T32ES007028 | Biochim Biophys Acta Mol Basis Dis (2017 06) |
28213125
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2017 |
| Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease. | Pfalzer, Anna C; Bowman, Aaron B | R01ES010563, T32ES007028 | Curr Environ Health Rep (2017 Jun) |
28417441
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2017 |
| Structure of a DNA glycosylase that unhooks interstrand cross-links. | Mullins, Elwood A; Warren, Garrett M; Bradley, Noah P; Eichman, Brandt F | T32ES007028 | Proc Natl Acad Sci U S A (2017 Apr 25) |
28396405
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2017 |
| Toxicity and repair of DNA adducts produced by the natural product yatakemycin. | Mullins, Elwood A; Shi, Rongxin; Eichman, Brandt F | T32ES007028 | Nat Chem Biol (2017 Sep) |
28759018
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2017 |
| A Catalytic Role for C-H/π Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase A ... | Parsons, Zachary D; Bland, Joshua M; Mullins, Elwood A; Eichman, Brandt F | T32ES007028 | J Am Chem Soc (2016 Sep 14) |
27571247
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2016 |
| Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in R ... | Federspiel, Joel D; Codreanu, Simona G; Palubinsky, Amy M; Winland, Ama J; Betanzos, Carlos Mor ... | T32ES007028 | Mol Cell Proteomics (2016 06) |
27006476
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2016 |
| Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation. | Delahanty, Ryan J; Zhang, Yanfeng; Bichell, Terry Jo; Shen, Wangzhen; Verdier, Kelienne; Macdon ... | T32ES007028 | Cell Rep (2016 Dec 20) |
28009282
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2016 |
| Covalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progres ... | Camarillo, Jeannie M; Rose, Kristie L; Galligan, James J; Xu, Shu; Marnett, Lawrence J | T32ES007028 | Chem Res Toxicol (2016 Mar 21) |
26910110
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2016 |
| Dynamic Phosphorylation of Apoptosis Signal Regulating Kinase 1 (ASK1) in Response to Oxidative and ... | Morales Betanzos, Carlos; Federspiel, Joel D; Palubinsky, Amy M; McLaughlin, BethAnn; Liebler, ... | T32ES007028 | Chem Res Toxicol (2016 Dec 19) |
27989136
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2016 |
| Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington's Disease. | Osmand, Alexander P; Bichell, Terry Jo; Bowman, Aaron B; Bates, Gillian P | T32ES007028 | J Huntingtons Dis (2016 Dec 15) |
27886014
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2016 |
| Human cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids. | Kramlinger, Valerie M; Nagy, Leslie D; Fujiwara, Rina; Johnson, Kevin M; Phan, Thanh T N; Xiao, ... | T32ES007028 | FEBS Lett (2016 May) |
27059013
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2016 |
| Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A. | Patrone, James D; Pelz, Nicholas F; Bates, Brittney S; Souza-Fagundes, Elaine M; Vangamudi, Bha ... | T32ES007028 | ChemMedChem (2016 Apr 19) |
26748787
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2016 |
| Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hyper ... | Norlander, Allison E; Saleh, Mohamed A; Kamat, Nikhil V; Ko, Benjamin; Gnecco, Juan; Zhu, Linj ... | T32ES007028 | Hypertension (2016 07) |
27141060
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2016 |
| Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted La ... | Prentice, Boone M; Chumbley, Chad W; Hachey, Brian C; Norris, Jeremy L; Caprioli, Richard M | T32ES007028 | Anal Chem (2016 Oct 04) |
27573922
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2016 |
| NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabdi ... | Caito, Samuel W; Aschner, Michael | R01ES007331, T32ES007028 | Toxicol Sci (2016 May) |
26865665
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2016 |
| Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13 ... | Shimada, Tsutomu; Takenaka, Shigeo; Murayama, Norie; Kramlinger, Valerie M; Kim, Joo-Hwan; Kim, ... | T32ES007028 | Xenobiotica (2016) |
26247835
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2016 |
| Rapid kinetic methods to dissect steroidogenic cytochrome P450 reaction mechanisms. | Yoshimoto, Francis K; Auchus, Richard J | T32ES007028 | J Steroid Biochem Mol Biol (2016 Jul) |
26472553
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2016 |
| Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through ... | Nguyen, Thuy T; Caito, Samuel W; Zackert, William E; West, James D; Zhu, Shijun; Aschner, Mich ... | R01ES007331, R01ES010563, T32ES007028 | Aging (Albany NY) (2016 08) |
27514077
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2016 |
| Specificity of Protein Covalent Modification by the Electrophilic Proteasome Inhibitor Carfilzomib i ... | Federspiel, Joel D; Codreanu, Simona G; Goyal, Sandeep; Albertolle, Matthew E; Lowe, Eric; Teag ... | T32ES007028 | Mol Cell Proteomics (2016 10) |
27503896
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2016 |
| The Response of Acinetobacter baumannii to Zinc Starvation. | Nairn, Brittany L; Lonergan, Zachery R; Wang, Jiefei; Braymer, Joseph J; Zhang, Yaofang; Calcut ... | T32ES007028 | Cell Host Microbe (2016 Jun 08) |
27281572
|
2016 |
| Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips. | Pensabene, Virginia; Costa, Lino; Terekhov, Alexander Y; Gnecco, Juan S; Wikswo, John P; Hofmei ... | T32ES007028 | ACS Appl Mater Interfaces (2016 Aug 31) |
27513606
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2016 |
| A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in ... | Mullins, Elwood A; Shi, Rongxin; Kotsch, Lyle A; Eichman, Brandt F | T32ES007028 | PLoS One (2015) |
25978435
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2015 |
| A whole genome RNAi screen identifies replication stress response genes. | Kavanaugh, Gina; Ye, Fei; Mohni, Kareem N; Luzwick, Jessica W; Glick, Gloria; Cortez, David | T32ES007028 | DNA Repair (Amst) (2015 Nov) |
26454783
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2015 |
| Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in ... | Pancani, Tristano; Foster, Daniel J; Moehle, Mark S; Bichell, Terry Jo; Bradley, Emma; Bridges, ... | T32ES007028 | Proc Natl Acad Sci U S A (2015 Nov 10) |
26508634
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2015 |
| Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq ... | Wilde, Aimee D; Snyder, Daniel J; Putnam, Nicole E; Valentino, Michael D; Hammer, Neal D; Loner ... | T32ES007028 | PLoS Pathog (2015 Dec) |
26684646
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2015 |
| Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA ... | Stavros, Kallie M; Hawkins, Edward K; Rizzo, Carmelo J; Stone, Michael P | T32ES007028 | Chem Res Toxicol (2015 Jul 20) |
26083477
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2015 |
| Competition and allostery govern substrate selectivity of cyclooxygenase-2. | Mitchener, Michelle M; Hermanson, Daniel J; Shockley, Erin M; Brown, H Alex; Lindsley, Craig W; ... | T32ES007028 | Proc Natl Acad Sci U S A (2015 Oct 06) |
26392530
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2015 |
| Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2. | Enright, Jennifer M; Toomey, Matthew B; Sato, Shin-ya; Temple, Shelby E; Allen, James R; Fujiwa ... | T32ES007028 | Curr Biol (2015 Dec 07) |
26549260
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2015 |
| Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Pr ... | Kavanaugh, Gina; Zhao, Runxiang; Guo, Yan; Mohni, Kareem N; Glick, Gloria; Lacy, Monica E; Hut ... | T32ES007028 | Mol Cell Biol (2015 Sep 01) |
26100022
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2015 |
| High-speed MALDI MS/MS imaging mass spectrometry using continuous raster sampling. | Prentice, Boone M; Chumbley, Chad W; Caprioli, Richard M | T32ES007028 | J Mass Spectrom (2015 Apr) |
26149115
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2015 |
| Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE S ... | Pallan, Pradeep S; Wang, Chunxue; Lei, Li; Yoshimoto, Francis K; Auchus, Richard J; Waterman, ... | T32ES007028 | J Biol Chem (2015 May 22) |
25855791
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2015 |
| Manganese Is Essential for Neuronal Health. | Horning, Kyle J; Caito, Samuel W; Tipps, K Grace; Bowman, Aaron B; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Annu Rev Nutr (2015) |
25974698
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2015 |
| Novel approaches to identify protein adducts produced by lipid peroxidation. | Codreanu, S G; Liebler, D C | T32ES007028 | Free Radic Res (2015) |
25819163
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2015 |
| Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and ... | Wegrzynowicz, Michal; Bichell, Terry Jo; Soares, Barbara D; Loth, Meredith K; McGlothan, Jennif ... | P30ES009089, R01ES007062, T32ES007028, T32ES007322 | J Huntingtons Dis (2015) |
26333255
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2015 |
| Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4 ... | Aluise, Christopher D; Camarillo, Jeannie M; Shimozu, Yuki; Galligan, James J; Rose, Kristie L; ... | T32ES007028 | Chem Res Toxicol (2015 Apr 20) |
25739016
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2015 |
| Staphylococcus aureus CstB Is a Novel Multidomain Persulfide Dioxygenase-Sulfurtransferase Involved ... | Shen, Jiangchuan; Keithly, Mary E; Armstrong, Richard N; Higgins, Khadine A; Edmonds, Katherine ... | T32ES007028 | Biochemistry (2015 Jul 28) |
26177047
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2015 |
| Structural and kinetic basis of steroid 17α,20-lyase activity in teleost fish cytochrome P450 17A1 a ... | Pallan, Pradeep S; Nagy, Leslie D; Lei, Li; Gonzalez, Eric; Kramlinger, Valerie M; Azumaya, Ca ... | T32ES007028 | J Biol Chem (2015 Feb 06) |
25533464
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2015 |
| The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. | Mullins, Elwood A; Shi, Rongxin; Parsons, Zachary D; Yuen, Philip K; David, Sheila S; Igarashi, ... | T32ES007028 | Nature (2015 Nov 12) |
26524531
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2015 |
| A highly sensitive method for analysis of 7-dehydrocholesterol for the study of Smith-Lemli-Opitz sy ... | Liu, Wei; Xu, Libin; Lamberson, Connor; Haas, Dorothea; Korade, Zeljka; Porter, Ned A | T32ES007028 | J Lipid Res (2014 Feb) |
24259532
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2014 |
| A structure-specific nucleic acid-binding domain conserved among DNA repair proteins. | Mason, Aaron C; Rambo, Robert P; Greer, Briana; Pritchett, Michael; Tainer, John A; Cortez, Da ... | T32ES007028 | Proc Natl Acad Sci U S A (2014 May 27) |
24821763
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2014 |
| Alkylation damage by lipid electrophiles targets functional protein systems. | Codreanu, Simona G; Ullery, Jody C; Zhu, Jing; Tallman, Keri A; Beavers, William N; Porter, Ne ... | T32ES007028 | Mol Cell Proteomics (2014 Mar) |
24429493
|
2014 |
| Base-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI ... | Stavros, Kallie M; Hawkins, Edward K; Rizzo, Carmelo J; Stone, Michael P | T32ES007028 | Nucleic Acids Res (2014 Mar) |
24366876
|
2014 |
| BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuro ... | Stansfield, Kirstie H; Bichell, Terry Jo; Bowman, Aaron B; Guilarte, Tomás R | P30ES009089, T32ES007028 | J Neurochem (2014 Dec) |
25099302
|
2014 |
| Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A. | Frank, Andreas O; Vangamudi, Bhavatarini; Feldkamp, Michael D; Souza-Fagundes, Elaine M; Luzwick ... | T32ES007028 | J Med Chem (2014 Mar 27) |
24491171
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2014 |
| Elucidation of kinetic mechanisms of human translesion DNA polymerase κ using tryptophan mutants. | Zhao, Linlin; Pence, Matthew G; Eoff, Robert L; Yuan, Shuai; Fercu, Catinca A; Guengerich, F P ... | T32ES007028 | FEBS J (2014 Oct) |
25065501
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2014 |
| Mechanism of the third oxidative step in the conversion of androgens to estrogens by cytochrome P450 ... | Yoshimoto, Francis K; Guengerich, F Peter | T32ES007028 | J Am Chem Soc (2014 Oct 22) |
25252141
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2014 |
| Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) ... | Caito, Samuel; Zeng, Heng; Aschner, Judy L; Aschner, Michael | R01ES007331, T32ES007028 | PLoS One (2014) |
24852575
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2014 |
| Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct ... | Lin, Ying-Chih; Li, Liang; Makarova, Alena V; Burgers, Peter M; Stone, Michael P; Lloyd, R Ste ... | T32ES007028 | Carcinogenesis (2014 Jul) |
24398669
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2014 |
| Oxidation of endogenous N-arachidonoylserotonin by human cytochrome P450 2U1. | Siller, Michal; Goyal, Sandeep; Yoshimoto, Francis K; Xiao, Yi; Wei, Shouzou; Guengerich, F Pe ... | T32ES007028 | J Biol Chem (2014 Apr 11) |
24563460
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2014 |
| Phosphorylation of a C-terminal auto-inhibitory domain increases SMARCAL1 activity. | Carroll, Clinton; Bansbach, Carol E; Zhao, Runxiang; Jung, Sung Yun; Qin, Jun; Cortez, David | T32ES007028 | Nucleic Acids Res (2014 Jan) |
24150942
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2014 |
| Protein modification by adenine propenal. | Shuck, Sarah C; Wauchope, Orrette R; Rose, Kristie L; Kingsley, Philip J; Rouzer, Carol A; Shel ... | T32ES007028 | Chem Res Toxicol (2014 Oct 20) |
25211669
|
2014 |
| Stable histone adduction by 4-oxo-2-nonenal: a potential link between oxidative stress and epigeneti ... | Galligan, James J; Rose, Kristie L; Beavers, William N; Hill, Salisha; Tallman, Keri A; Tansey, ... | T32ES007028 | J Am Chem Soc (2014 Aug 27) |
25099620
|
2014 |
| The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein ... | Bornhorst, Julia; Chakraborty, Sudipta; Meyer, Sören; Lohren, Hanna; Brinkhaus, Sigrid Grosse; ... | R01ES010563, T32ES007028 | Metallomics (2014 Mar) |
24452053
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2014 |
| The substrate binding interface of alkylpurine DNA glycosylase AlkD. | Mullins, Elwood A; Rubinson, Emily H; Eichman, Brandt F | T32ES007028 | DNA Repair (Amst) (2014 Jan) |
24286669
|
2014 |
| Unusual kinetic isotope effects of deuterium reinforced polyunsaturated fatty acids in tocopherol-me ... | Lamberson, Connor R; Xu, Libin; Muchalski, Hubert; Montenegro-Burke, J Rafael; Shmanai, Vadim V ... | T32ES007028 | J Am Chem Soc (2014 Jan 22) |
24380377
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2014 |
| An HPLC-tandem mass spectrometry method for simultaneous detection of alkylated base excision repair ... | Mullins, Elwood A; Rubinson, Emily H; Pereira, Kevin N; Calcutt, M Wade; Christov, Plamen P; Ei ... | T32ES007028 | Methods (2013 Nov) |
23876937
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2013 |
| Assays of plasma dehydrocholesteryl esters and oxysterols from Smith-Lemli-Opitz syndrome patients. | Liu, Wei; Xu, Libin; Lamberson, Connor R; Merkens, Louise S; Steiner, Robert D; Elias, Ellen R ... | T32ES007028 | J Lipid Res (2013 Jan) |
23072947
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2013 |
| ATR phosphorylates SMARCAL1 to prevent replication fork collapse. | Couch, Frank B; Bansbach, Carol E; Driscoll, Robert; Luzwick, Jessica W; Glick, Gloria G; Bétou ... | R01ES016486, T32ES007028 | Genes Dev (2013 Jul 15) |
23873943
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2013 |
| Cobalt carbonyl complexes as probes for alkyne-tagged lipids. | Tallman, Keri A; Armstrong, Michelle D; Milne, Stephen B; Marnett, Lawrence J; Brown, H Alex; P ... | T32ES007028 | J Lipid Res (2013 Mar) |
23307946
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2013 |
| Depurination of N7-methylguanine by DNA glycosylase AlkD is dependent on the DNA backbone. | Rubinson, Emily H; Christov, Plamen P; Eichman, Brandt F | T32ES007028 | Biochemistry (2013 Oct 22) |
24090276
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2013 |
| Differential response to acrylonitrile toxicity in rat primary astrocytes and microglia. | Caito, Samuel; Yu, Yingchun; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Neurotoxicology (2013 Jul) |
23628792
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2013 |
| Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragme ... | Frank, Andreas O; Feldkamp, Michael D; Kennedy, J Phillip; Waterson, Alex G; Pelz, Nicholas F; ... | T32ES007028 | J Med Chem (2013 Nov 27) |
24147804
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2013 |
| Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. | Patrone, James D; Kennedy, J Phillip; Frank, Andreas O; Feldkamp, Michael D; Vangamudi, Bhavata ... | T32ES007028 | ACS Med Chem Lett (2013 Jul 11) |
23914285
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2013 |
| DNA damage response: three levels of DNA repair regulation. | Sirbu, Bianca M; Cortez, David | T32ES007028 | Cold Spring Harb Perspect Biol (2013 Aug) |
23813586
|
2013 |
| Dopaminergic neurotoxicity of S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, and S-methyl-N,N-d ... | Caito, Samuel W; Valentine, William M; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | J Neurochem (2013 Dec) |
23786526
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2013 |
| Early-life exposure to methylmercury in wildtype and pdr-1/parkin knockout C. elegans. | Martinez-Finley, Ebany J; Chakraborty, Sudipta; Slaughter, James C; Aschner, Michael | R01ES007331, T32ES007028 | Neurochem Res (2013 Aug) |
23609499
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2013 |
| HDAC3 is essential for DNA replication in hematopoietic progenitor cells. | Summers, Alyssa R; Fischer, Melissa A; Stengel, Kristy R; Zhao, Yue; Kaiser, Jonathan F; Wells, ... | T32ES007028 | J Clin Invest (2013 Jul) |
23921131
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2013 |
| Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the proce ... | Nagarajan, Prabakaran; Ge, Zhongqi; Sirbu, Bianca; Doughty, Cheryl; Agudelo Garcia, Paula A; Sc ... | T32ES007028 | PLoS Genet (2013 Jun) |
23754951
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2013 |
| Identification of proteins at active, stalled, and collapsed replication forks using isolation of pr ... | Sirbu, Bianca M; McDonald, W Hayes; Dungrawala, Huzefa; Badu-Nkansah, Akosua; Kavanaugh, Gina M ... | T32ES007028 | J Biol Chem (2013 Nov 01) |
24047897
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2013 |
| Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. | Wells, Christina E; Bhaskara, Srividya; Stengel, Kristy R; Zhao, Yue; Sirbu, Bianca; Chagot, B ... | T32ES007028 | PLoS One (2013) |
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2013 |
| Involvement of AAT transporters in methylmercury toxicity in Caenorhabditis elegans. | Caito, Samuel W; Zhang, Yaofang; Aschner, Michael | R01ES007331, T32ES007028 | Biochem Biophys Res Commun (2013 Jun 14) |
23669041
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2013 |
| Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. | Ketkar, Amit; Zafar, Maroof K; Maddukuri, Leena; Yamanaka, Kinrin; Banerjee, Surajit; Egli, Ma ... | T32ES007028 | Chem Res Toxicol (2013 Feb 18) |
23305233
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2013 |
| Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations. | DeWitt, Margaret R; Chen, Pan; Aschner, Michael | R01ES010563, T32ES007028 | Biochem Biophys Res Commun (2013 Mar 01) |
23357421
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2013 |
| Manganese neurotoxicity and the role of reactive oxygen species. | Martinez-Finley, Ebany J; Gavin, Claire E; Aschner, Michael; Gunter, Thomas E | R01ES010563, T32ES007028 | Free Radic Biol Med (2013 Sep) |
23395780
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2013 |
| Metal-induced neurodegeneration in C. elegans. | Chen, Pan; Martinez-Finley, Ebany J; Bornhorst, Julia; Chakraborty, Sudipta; Aschner, Michael | R01ES010563, T32ES007028 | Front Aging Neurosci (2013) |
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2013 |
| NMR studies of the interaction of calmodulin with IQ motif peptides. | Damo, Steven M; Feldkamp, Michael D; Chagot, Benjamin; Chazin, Walter J | T32ES007028 | Methods Mol Biol (2013) |
23296611
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2013 |
| Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C. elegan ... | Chakraborty, Sudipta; Bornhorst, Julia; Nguyen, Thuy T; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Int J Mol Sci (2013 Nov 21) |
24284401
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2013 |
| Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome. | Windsor, Katherine; Genaro-Mattos, Thiago C; Kim, Hye-Young H; Liu, Wei; Tallman, Keri A; Miyam ... | T32ES007028 | J Lipid Res (2013 Oct) |
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2013 |
| Recent advances in the structural mechanisms of DNA glycosylases. | Brooks, Sonja C; Adhikary, Suraj; Rubinson, Emily H; Eichman, Brandt F | T32ES007028 | Biochim Biophys Acta (2013 Jan) |
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2013 |
| Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine. | Maddukuri, Leena; Shuck, Sarah C; Eoff, Robert L; Zhao, Linlin; Rizzo, Carmelo J; Guengerich, ... | T32ES007028 | Biochemistry (2013 Dec 03) |
24171480
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2013 |
| Simplified synthesis of individual stereoisomers of the 4-hydroxynonenal adducts of deoxyguanosine. | Christov, Plamen P; Hawkins, Edward K; Kett, Nathan R; Rizzo, Carmelo J | T32ES007028 | Tetrahedron Lett (2013 Aug 07) |
23935223
|
2013 |
| Structural and chemical aspects of resistance to the antibiotic fosfomycin conferred by FosB from Ba ... | Thompson, Matthew K; Keithly, Mary E; Harp, Joel; Cook, Paul D; Jagessar, Kevin L; Sulikowski, ... | T32ES007028 | Biochemistry (2013 Oct 15) |
24004181
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2013 |
| Substrate-selective repair and restart of replication forks by DNA translocases. | Bétous, Rémy; Couch, Frank B; Mason, Aaron C; Eichman, Brandt F; Manosas, Maria; Cortez, David | T32ES007028 | Cell Rep (2013 Jun 27) |
23746452
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2013 |
| Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication prote ... | Feldkamp, Michael D; Frank, Andreas O; Kennedy, J Phillip; Patrone, James D; Vangamudi, Bhavata ... | T32ES007028 | Biochemistry (2013 Sep 17) |
23962067
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2013 |
| The Role of skn-1 in methylmercury-induced latent dopaminergic neurodegeneration. | Martinez-Finley, Ebany J; Caito, Samuel; Slaughter, James C; Aschner, Michael | R01ES007331, T32ES007028 | Neurochem Res (2013 Dec) |
24194349
|
2013 |
| Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DN ... | Shell, Steven M; Hawkins, Edward K; Tsai, Miaw-Sheue; Hlaing, Aye Su; Rizzo, Carmelo J; Chazin, ... | T32ES007028 | DNA Repair (Amst) (2013 Nov) |
24051049
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2013 |
| A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication prote ... | Souza-Fagundes, Elaine M; Frank, Andreas O; Feldkamp, Michael D; Dorset, Daniel C; Chazin, Walt ... | T32ES007028 | Anal Biochem (2012 Feb 15) |
22197419
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2012 |
| Altered manganese homeostasis: implications for BLI-3-dependent dopaminergic neurodegeneration and S ... | Chakraborty, Sudipta; Aschner, Michael | T32ES007028 | J Trace Elem Med Biol (2012 Jun) |
22591558
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2012 |
| Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases. | Zhao, Linlin; Pence, Matthew G; Christov, Plamen P; Wawrzak, Zdzislaw; Choi, Jeong-Yun; Rizzo, ... | T32ES007028 | J Biol Chem (2012 Oct 12) |
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2012 |
| Cellular transport and homeostasis of essential and nonessential metals. | Martinez-Finley, Ebany J; Chakraborty, Sudipta; Fretham, Stephanie J B; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Metallomics (2012 Jul) |
22337135
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2012 |
| Electrophilic adduction of ubiquitin activating enzyme E1 by N,N-diethyldithiocarbamate inhibits ubi ... | Viquez, Olga M; Caito, Samuel W; McDonald, W Hayes; Friedman, David B; Valentine, William M | T32ES007028 | Chem Res Toxicol (2012 Nov 19) |
22874009
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2012 |
| Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans. | Caito, Samuel; Fretham, Stephanie; Martinez-Finley, Ebany; Chakraborty, Sudipta; Avila, Daiana; ... | R01ES007331, R01ES010563, T32ES007028 | Front Genet (2012) |
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2012 |
| Mechanisms and Modifiers of Methylmercury-Induced Neurotoxicity. | Fretham, Stephanie Jb; Caito, Samuel; Martinez-Finley, Ebany J; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Toxicol Res (Camb) (2012 Jul 01) |
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2012 |
| Nucleic acid recognition by tandem helical repeats. | Rubinson, Emily H; Eichman, Brandt F | T32ES007028 | Curr Opin Struct Biol (2012 Feb) |
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2012 |
| Oxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4. | Cheng, Qian; Sohl, Christal D; Yoshimoto, Francis K; Guengerich, F Peter | T32ES007028 | J Biol Chem (2012 Aug 24) |
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2012 |
| Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1. | Chowdhury, Goutam; Calcutt, M Wade; Nagy, Leslie D; Guengerich, F Peter | T32ES007028 | Biochemistry (2012 Dec 18) |
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2012 |
| Replication of N2,3-ethenoguanine by DNA polymerases. | Zhao, Linlin; Christov, Plamen P; Kozekov, Ivan D; Pence, Matthew G; Pallan, Pradeep S; Rizzo, ... | T32ES007028 | Angew Chem Int Ed Engl (2012 May 29) |
22488769
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2012 |
| SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability duri ... | Bétous, Rémy; Mason, Aaron C; Rambo, Robert P; Bansbach, Carol E; Badu-Nkansah, Akosua; Sirbu, ... | T32ES007028 | Genes Dev (2012 Jan 15) |
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2012 |
| Synthesis of bacillithiol and the catalytic selectivity of FosB-type fosfomycin resistance proteins. | Lamers, Alexander P; Keithly, Mary E; Kim, Kwangho; Cook, Paul D; Stec, Donald F; Hines, Kelly ... | T32ES007028 | Org Lett (2012 Oct 19) |
23030527
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2012 |
| XPF-ERCC1: on the bubble. | Shell, Steven M; Chazin, Walter J | T32ES007028 | Structure (2012 Apr 04) |
22483102
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2012 |
| A single chiroptical spectroscopic method may not be able to establish the absolute configurations o ... | Polavarapu, Prasad L; Donahue, Emily A; Shanmugam, Ganesh; Scalmani, Giovanni; Hawkins, Edward ... | T32ES007028 | J Phys Chem A (2011 Jun 09) |
21568330
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2011 |
| Importance of solvation in understanding the chiroptical spectra of natural products in solution pha ... | Polavarapu, Prasad L; Scalmani, Giovanni; Hawkins, Edward K; Rizzo, Carmelo; Jeirath, Neha; Ibn ... | T32ES007028 | J Nat Prod (2011 Mar 25) |
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2011 |
| Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases. | Martinez-Finley, Ebany J; Avila, Daiana Silva; Chakraborty, Sudipta; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Metallomics (2011 Mar) |
21210060
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2011 |
| Lack of association between autism and four heavy metal regulatory genes. | Owens, Sarah E; Summar, Marshall L; Ryckman, Kelli K; Haines, Jonathan L; Reiss, Sara; Summar, ... | R01ES007331, T32ES007028 | Neurotoxicology (2011 Dec) |
21798283
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2011 |
| Location of inhibitor binding sites in the human inducible prostaglandin E synthase, MPGES1. | Prage, Edward B; Pawelzik, Sven-Christian; Busenlehner, Laura S; Kim, Kwangho; Morgenstern, Ral ... | T32ES007028 | Biochemistry (2011 Sep 06) |
21805999
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2011 |
| Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase. | Milatovic, Dejan; Jenkins, Jerry W; Hood, Jonathan E; Yu, Yingchun; Rongzhu, Lu; Aschner, Mich ... | R01ES007331, R01ES010563, T32ES007028 | Neurotoxicology (2011 Oct) |
21241737
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2011 |
| Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and ... | Guengerich, F Peter; Sohl, Christal D; Chowdhury, Goutam | T32ES007028 | Arch Biochem Biophys (2011 Mar 01) |
20804723
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2011 |
| Progression of neurodegeneration and morphologic changes in the brains of juvenile mice with selenop ... | Caito, Samuel W; Milatovic, Dejan; Hill, Kristina E; Aschner, Michael; Burk, Raymond F; Valenti ... | T32ES007028 | Brain Res (2011 Jun 29) |
21636077
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2011 |
| Roles of the four DNA polymerases of the crenarchaeon Sulfolobus solfataricus and accessory proteins ... | Choi, Jeong-Yun; Eoff, Robert L; Pence, Matthew G; Wang, Jian; Martin, Martha V; Kim, Eun-Jin; ... | T32ES007028 | J Biol Chem (2011 Sep 09) |
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2011 |
| Structure and function of YghU, a nu-class glutathione transferase related to YfcG from Escherichia ... | Stourman, Nina V; Branch, Megan C; Schaab, Matthew R; Harp, Joel M; Ladner, Jane E; Armstrong, ... | T32ES007028 | Biochemistry (2011 Feb 22) |
21222452
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2011 |
| Structure-activity analysis of diffusible lipid electrophiles associated with phospholipid peroxidat ... | McGrath, Colleen E; Tallman, Keri A; Porter, Ned A; Marnett, Lawrence J | T32ES007028 | Chem Res Toxicol (2011 Mar 21) |
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2011 |
| An unprecedented nucleic acid capture mechanism for excision of DNA damage. | Rubinson, Emily H; Gowda, A S Prakasha; Spratt, Thomas E; Gold, Barry; Eichman, Brandt F | T32ES007028 | Nature (2010 Nov 18) |
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2010 |
| Hormetic effect of methylmercury on Caenorhabditis elegans. | Helmcke, Kirsten J; Aschner, Michael | R01ES007331, R01ES010563, T32ES007028 | Toxicol Appl Pharmacol (2010 Oct 15) |
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2010 |
| Kinetic analysis of the three-step steroid aromatase reaction of human cytochrome P450 19A1. | Sohl, Christal D; Guengerich, F Peter | T32ES007028 | J Biol Chem (2010 Jun 04) |
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2010 |
| Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma. | Oppenheimer, Stacey R; Mi, Deming; Sanders, Melinda E; Caprioli, Richard M | T32ES007028 | J Proteome Res (2010 May 07) |
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2010 |
| Mutagenicity of a glutathione conjugate of butadiene diepoxide. | Cho, Sung-Hee; Loecken, Elisabeth M; Guengerich, F Peter | T32ES007028 | Chem Res Toxicol (2010 Oct 18) |
20879737
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2010 |
| Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes an ... | Chowdhury, Goutam; Calcutt, M Wade; Guengerich, F Peter | T32ES007028 | J Biol Chem (2010 Mar 12) |
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2010 |
| Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymer ... | Pence, Matthew G; Choi, Jeong-Yun; Egli, Martin; Guengerich, F Peter | T32ES007028 | J Biol Chem (2010 Dec 24) |
20961860
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2010 |
| The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue ... | Christov, Plamen P; Chowdhury, Goutam; Garmendia, Craig A; Wang, Feng; Stover, James S; Elmquis ... | T32ES007028 | Chem Res Toxicol (2010 Jun 21) |
20377178
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2010 |
| Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Ald ... | Shchepin, Roman; Möller, Matias N; Kim, Hye-young H; Hatch, Duane M; Bartesaghi, Silvina; Kalya ... | T32ES007028 | J Am Chem Soc (2010 Dec 15) |
21090613
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2010 |
| Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inac ... | Turman, Melissa V; Kingsley, Philip J; Marnett, Lawrence J | T32ES007028 | Biochemistry (2009 Dec 29) |
19928795
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2009 |
| Characterization of the effects of methylmercury on Caenorhabditis elegans. | Helmcke, Kirsten J; Syversen, Tore; Miller 3rd, David M; Aschner, Michael | R01ES007331, T32ES007028 | Toxicol Appl Pharmacol (2009 Oct 15) |
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2009 |
| Evolution of the antibiotic resistance protein, FosA, is linked to a catalytically promiscuous proge ... | Brown, Daniel W; Schaab, Matthew R; Birmingham, William R; Armstrong, Richard N | T32ES007028 | Biochemistry (2009 Mar 10) |
19196010
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2009 |
| Oxidation and glycolytic cleavage of etheno and propano DNA base adducts. | Knutson, Charles G; Rubinson, Emily H; Akingbade, Dapo; Anderson, Carolyn S; Stec, Donald F; Pe ... | T32ES007028 | Biochemistry (2009 Feb 3) |
19132922
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2009 |
| The bis-electrophile diepoxybutane cross-links DNA to human histones but does not result in enhanced ... | Loecken, Elisabeth M; Dasari, Surendra; Hill, Salisha; Tabb, David L; Guengerich, F Peter | T32ES007028 | Chem Res Toxicol (2009 Jun) |
19364102
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2009 |
| "One-pot" syntheses of malondialdehyde adducts of nucleosides. | Szekely, Jozsef; Wang, Hao; Peplowski, Katherine M; Knutson, Charles G; Marnett, Lawrence J; Ri ... | T32ES007028 | Nucleosides Nucleotides Nucleic Acids (2008 Feb) |
18205065
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2008 |
| A new protein architecture for processing alkylation damaged DNA: the crystal structure of DNA glyco ... | Rubinson, Emily H; Metz, Audrey H; O'Quin, Jami; Eichman, Brandt F | T32ES007028 | J Mol Biol (2008 Aug 01) |
18585735
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2008 |
| Cooperativity of cytochrome P450 1A2: interactions of 1,4-phenylene diisocyanide and 1-isopropoxy-4- ... | Isin, Emre M; Sohl, Christal D; Eoff, Robert L; Guengerich, F Peter | T32ES007028 | Arch Biochem Biophys (2008 May 1) |
18328798
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2008 |
| Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI. | VanderVeen, Laurie A; Harris, Thomas M; Jen-Jacobson, Linda; Marnett, Lawrence J | T32ES007028 | Chem Res Toxicol (2008 Sep) |
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2008 |
| Mitochondrial protein targets of thiol-reactive electrophiles. | Wong, Hansen L; Liebler, Daniel C | T32ES007028 | Chem Res Toxicol (2008 Apr) |
18324786
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2008 |
| Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D- ... | Knutson, Charles G; Skipper, Paul L; Liberman, Rosa G; Tannenbaum, Steven R; Marnett, Lawrence ... | T32ES007028 | Chem Res Toxicol (2008 Jun) |
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2008 |
| mRNA distribution and heterologous expression of orphan cytochrome P450 20A1. | Stark, Katarina; Wu, Zhong-Liu; Bartleson, Cheryl J; Guengerich, F Peter | T32ES007028 | Drug Metab Dispos (2008 Sep) |
18541694
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2008 |
| Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine. | Turman, Melissa V; Kingsley, Philip J; Rouzer, Carol A; Cravatt, Benjamin F; Marnett, Lawrence ... | T32ES007028 | Biochemistry (2008 Mar 25) |
18311922
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2008 |
| Protein damage by reactive electrophiles: targets and consequences. | Liebler, Daniel C | T32ES007028 | Chem Res Toxicol (2008 Jan) |
18052106
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2008 |
| Reactions of glyceraldehyde 3-phosphate dehydrogenase sulfhydryl groups with bis-electrophiles produ ... | Loecken, Elisabeth M; Guengerich, F Peter | T32ES007028 | Chem Res Toxicol (2008 Feb) |
18163542
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2008 |
| Structural elements involved in proton translocation by cytochrome c oxidase as revealed by backbone ... | Busenlehner, Laura S; Brändén, Gisela; Namslauer, Ida; Brzezinski, Peter; Armstrong, Richard N | T32ES007028 | Biochemistry (2008 Jan 8) |
18052347
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2008 |
| 2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomona ... | Thompson, Lawrence C; Ladner, Jane E; Codreanu, Simona G; Harp, Joel; Gilliland, Gary L; Armstr ... | T32ES007028 | Biochemistry (2007 Jun 12) |
17508726
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2007 |
| A model for glutathione binding and activation in the fosfomycin resistance protein, FosA. | Rigsby, Rachel E; Brown, Daniel W; Dawson, Eric; Lybrand, Terry P; Armstrong, Richard N | T32ES007028 | Arch Biochem Biophys (2007 Aug 15) |
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2007 |
| Chemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosine. | Stover, James S; Ciobanu, Madalina; Cliffel, David E; Rizzo, Carmelo J | T32ES007028 | J Am Chem Soc (2007 Feb 21) |
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2007 |
| Conformational differences of the C8-deoxyguanosine adduct of 2-amino-3-methylimidazo[4,5-f]quinolin ... | Elmquist, C Eric; Wang, Feng; Stover, James S; Stone, Michael P; Rizzo, Carmelo J | T32ES007028 | Chem Res Toxicol (2007 Mar) |
17311423
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2007 |
| DNA sequence modulates the conformation of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline ... | Wang, Feng; Elmquist, C Eric; Stover, James S; Rizzo, Carmelo J; Stone, Michael P | T32ES007028 | Biochemistry (2007 Jul 24) |
17602664
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2007 |
| Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its abi ... | Liu, Liping; Watanabe, Kengo; Fang, Qingming; Williams, Kevin M; Guengerich, F Peter; Pegg, An ... | T32ES007028 | Chem Res Toxicol (2007 Jan) |
17226938
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2007 |
| Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty ... | Chun, Young-Jin; Shimada, Tsutomu; Sanchez-Ponce, Raymundo; Martin, Martha V; Lei, Li; Zhao, B ... | T32ES007028 | J Biol Chem (2007 Jun 15) |
17446171
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2007 |
| Identification of the peroxidation products of 13-hydroxy-gamma-linolenate and 15-hydroxyarachidonat ... | Rector, Christopher L; Stec, Donald F; Brash, Alan R; Porter, Ned A | T32ES007028 | Chem Res Toxicol (2007 Nov) |
17907784
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2007 |
| In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P4 ... | Dostalek, Miroslav; Brooks, Joshua D; Hardy, Klarissa D; Milne, Ginger L; Moore, Megan M; Sharm ... | T32ES007028 | Mol Pharmacol (2007 Dec) |
17898314
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2007 |
| Location of substrate binding sites within the integral membrane protein microsomal glutathione tran ... | Busenlehner, Laura S; Alander, Johan; Jegerscöhld, Caroline; Holm, Peter J; Bhakat, Priyaranjan ... | T32ES007028 | Biochemistry (2007 Mar 13) |
17297922
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2007 |
| Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-beta-D-erythropentofuranosyl)-py ... | Knutson, Charles G; Wang, Hao; Rizzo, Carmelo J; Marnett, Lawrence J | T32ES007028 | J Biol Chem (2007 Dec 14) |
17951255
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2007 |
| Metabolism in vitro and in vivo of the DNA base adduct, M1G. | Knutson, Charles G; Akingbade, Dapo; Crews, Brenda C; Voehler, Markus; Stec, Donald F; Marnett, ... | T32ES007028 | Chem Res Toxicol (2007 Mar) |
17311424
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2007 |
| Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases. | Prusakiewicz, Jeffery J; Turman, Melissa V; Vila, Andrew; Ball, Heather L; Al-Mestarihi, Ahmad ... | T32ES007028 | Arch Biochem Biophys (2007 Aug 15) |
17493578
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2007 |
| Structural basis of enantioselective inhibition of cyclooxygenase-1 by S-alpha-substituted indometha ... | Harman, Christine A; Turman, Melissa V; Kozak, Kevin R; Marnett, Lawrence J; Smith, William L; ... | T32ES007028 | J Biol Chem (2007 Sep 21) |
17656360
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2007 |
| Structure and mechanism of the genomically encoded fosfomycin resistance protein, FosX, from Listeri ... | Fillgrove, Kerry L; Pakhomova, Svetlana; Schaab, Matthew R; Newcomer, Marcia E; Armstrong, Rich ... | T32ES007028 | Biochemistry (2007 Jul 10) |
17567049
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2007 |
| Structure of the 1,N2-etheno-2'-deoxyguanosine adduct in duplex DNA at pH 8.6. | Shanmugam, Ganesh; Goodenough, Angela K; Kozekov, Ivan D; Guengerich, F Peter; Rizzo, Carmelo J ... | T32ES007028 | Chem Res Toxicol (2007 Nov) |
17941687
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2007 |
| Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-am ... | Stover, James S; Rizzo, Carmelo J | T32ES007028 | Chem Res Toxicol (2007 Dec) |
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2007 |
| Untargeted analysis of mass spectrometry data for elucidation of metabolites and function of enzymes ... | Sanchez-Ponce, Raymundo; Guengerich, F Peter | T32ES007028 | Anal Chem (2007 May 1) |
17408243
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2007 |
| Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in ... | Wang, Feng; DeMuro, Nicholas E; Elmquist, C Eric; Stover, James S; Rizzo, Carmelo J; Stone, Mi ... | T32ES007028 | J Am Chem Soc (2006 Aug 9) |
16881637
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2006 |
| Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta ... | Choi, Jeong-Yun; Stover, James S; Angel, Karen C; Chowdhury, Goutam; Rizzo, Carmelo J; Guengeri ... | T32ES007028 | J Biol Chem (2006 Sep 01) |
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2006 |
| Double mutation at the subunit interface of glutathione transferase rGSTM1-1 results in a stable, fo ... | Thompson, Lawrence C; Walters, John; Burke, Jonathan; Parsons, James F; Armstrong, Richard N; D ... | T32ES007028 | Biochemistry (2006 Feb 21) |
16475815
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2006 |
| In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG. | Otteneder, Michael B; Knutson, Charles G; Daniels, J Scott; Hashim, Muhammed; Crews, Brenda C; ... | T32ES007028 | Proc Natl Acad Sci U S A (2006 Apr 25) |
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2006 |
| Inhibition of protein phosphatase 2A activity by selective electrophile alkylation damage. | Codreanu, Simona G; Adams, Deanna G; Dawson, Eric S; Wadzinski, Brian E; Liebler, Daniel C | T32ES007028 | Biochemistry (2006 Aug 22) |
16906760
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2006 |
| Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxi ... | Busenlehner, Laura S; Salomonsson, Lina; Brzezinski, Peter; Armstrong, Richard N | T32ES007028 | Proc Natl Acad Sci U S A (2006 Oct 17) |
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2006 |
| Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases. | Choi, Jeong-Yun; Zang, Hong; Angel, Karen C; Kozekov, Ivan D; Goodenough, Angela K; Rizzo, Car ... | T32ES007028 | Chem Res Toxicol (2006 Jun) |
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2006 |
| Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-me ... | Stover, James S; Chowdhury, Goutam; Zang, Hong; Guengerich, F Peter; Rizzo, Carmelo J | T32ES007028 | Chem Res Toxicol (2006 Nov) |
17112239
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2006 |
| Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium is ... | Krauser, Joel A; Guengerich, F Peter | T32ES007028 | J Biol Chem (2005 May 20) |
15772082
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2005 |
| Differential DNA recognition and cleavage by EcoRI dependent on the dynamic equilibrium between the ... | VanderVeen, Laurie A; Druckova, Alexandra; Riggins, James N; Sorrells, Jennifer L; Guengerich, ... | T32ES007028 | Biochemistry (2005 Apr 5) |
15794640
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2005 |
| DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crysta ... | Zang, Hong; Goodenough, Angela K; Choi, Jeong-Yun; Irimia, Adriana; Loukachevitch, Lioudmila V; ... | T32ES007028 | J Biol Chem (2005 Aug 19) |
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2005 |
| Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase II alpha in vitro and i ... | Vélez-Cruz, Renier; Riggins, James N; Daniels, J Scott; Cai, Hongliang; Guengerich, F Peter; Ma ... | T32ES007028 | Biochemistry (2005 Mar 15) |
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2005 |
| Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. | Gao, Nan; Ishii, Kenichiro; Mirosevich, Janni; Kuwajima, Satoru; Oppenheimer, Stacey R; Roberts ... | T32ES007028 | Development (2005 Aug) |
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2005 |
| Identification and analysis of products formed from phospholipids in the free radical oxidation of h ... | Milne, Ginger L; Seal, Jennifer R; Havrilla, Christine M; Wijtmans, Maikel; Porter, Ned A | T32ES007028 | J Lipid Res (2005 Feb) |
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2005 |
| Influence of the dimer interface on glutathione transferase structure and dynamics revealed by amide ... | Codreanu, Simona G; Thompson, Lawrence C; Hachey, David L; Dirr, Heini W; Armstrong, Richard N | T32ES007028 | Biochemistry (2005 Aug 09) |
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2005 |
| Insights into enzyme structure and dynamics elucidated by amide H/D exchange mass spectrometry. | Busenlehner, Laura S; Armstrong, Richard N | T32ES007028 | Arch Biochem Biophys (2005 Jan 01) |
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2005 |
| Lipid-soluble 3-pyridinol antioxidants spare alpha-tocopherol and do not efficiently mediate peroxid ... | Kim, Hye-Young; Pratt, Derek A; Seal, Jennifer R; Wijtmans, Maikel; Porter, Ned A | T32ES007028 | J Med Chem (2005 Nov 3) |
16250637
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2005 |
| Peroxidation of polyunsaturated fatty acid methyl esters catalyzed by N-methyl benzohydroxamic acid: ... | Punta, Carlo; Rector, Christopher L; Porter, Ned A | T32ES007028 | Chem Res Toxicol (2005 Feb) |
15720142
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2005 |
| Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tet ... | Goodenough, Angela K; Kozekov, Ivan D; Zang, Hong; Choi, Jeong-Yun; Guengerich, F Peter; Harris ... | T32ES007028 | Chem Res Toxicol (2005 Nov) |
16300379
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2005 |
| Characterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alky ... | Liu, Liping; Hachey, David L; Valadez, Gerardo; Williams, Kevin M; Guengerich, F Peter; Loktion ... | T32ES007028 | J Biol Chem (2004 Feb 06) |
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2004 |
| Coupling products of nucleosides with the glyoxal adduct of deoxyguanosine. | Brock, Angela K; Kozekov, Ivan D; Rizzo, Carmelo J; Harris, Thomas M | T32ES007028 | Chem Res Toxicol (2004 Aug) |
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2004 |
| Factors influencing the autoxidation of fatty acids: effect of olefin geometry of the nonconjugated ... | Tallman, Keri A; Roschek Jr, Bill; Porter, Ned A | T32ES007028 | J Am Chem Soc (2004 Aug 4) |
15281813
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2004 |
| Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid sy ... | Guengerich, F Peter; Sorrells, Jennifer L; Schmitt, Sophie; Krauser, Joel A; Aryal, Pramod; Mei ... | T32ES007028 | J Med Chem (2004 Jun 03) |
15163202
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2004 |
| Global shifts in protein sumoylation in response to electrophile and oxidative stress. | Manza, Linda L; Codreanu, Simona G; Stamer, Sheryl L; Smith, Darrin L; Wells, K Sam; Roberts, ... | T32ES007028 | Chem Res Toxicol (2004 Dec) |
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2004 |
| In vitro bypass of malondialdehyde-deoxyguanosine adducts: differential base selection during extens ... | Hashim, Muhammed F; Riggins, James N; Schnetz-Boutaud, Nathalie; Voehler, Markus; Stone, Michae ... | T32ES007028 | Biochemistry (2004 Sep 21) |
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2004 |
| Kinetic and thermodynamic analysis of the hydrolytic ring-opening of the malondialdehyde-deoxyguanos ... | Riggins, James N; Daniels, J Scott; Rouzer, Carol A; Marnett, Lawrence J | T32ES007028 | J Am Chem Soc (2004 Jul 7) |
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2004 |
| Kinetics and mechanism of the general-acid-catalyzed ring-closure of the malondialdehyde-DNA adduct, ... | Riggins, James N; Pratt, Derek A; Voehler, Markus; Daniels, J Scott; Marnett, Lawrence J | T32ES007028 | J Am Chem Soc (2004 Sep 1) |
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2004 |
| Liquid chromatography coordination ion-spray mass spectrometry (LC-CIS-MS) of docosahexaenoate ester ... | Seal, Jennifer R; Porter, Ned A | T32ES007028 | Anal Bioanal Chem (2004 Feb) |
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2004 |
| N,N-diethyldithiocarbamate produces copper accumulation, lipid peroxidation, and myelin injury in ra ... | Tonkin, Elizabeth G; Valentine, Holly L; Milatovic, Dejan M; Valentine, William M | T32ES007028 | Toxicol Sci (2004 Sep) |
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2004 |
| O6-alkylguanine-DNA alkyltransferase has opposing effects in modulating the genotoxicity of dibromom ... | Liu, Liping; Williams, Kevin M; Guengerich, F Peter; Pegg, Anthony E | T32ES007028 | Chem Res Toxicol (2004 Jun) |
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2004 |
| Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochon ... | Ladner, Jane E; Parsons, James F; Rife, Chris L; Gilliland, Gary L; Armstrong, Richard N | T32ES007028 | Biochemistry (2004 Jan 20) |
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2004 |
| Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein ... | Rigsby, Rachel E; Rife, Chris L; Fillgrove, Kerry L; Newcomer, Marcia E; Armstrong, Richard N | T32ES007028 | Biochemistry (2004 Nov 2) |
15504029
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2004 |
| Rate-limiting steps in oxidations catalyzed by rabbit cytochrome P450 1A2. | Guengerich, F Peter; Krauser, Joel A; Johnson, William W | T32ES007028 | Biochemistry (2004 Aug 24) |
15311939
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2004 |
| Site-specific synthesis and properties of oligonucleotides containing C8-deoxyguanosine adducts of t ... | Elmquist, C Eric; Stover, James S; Wang, Zhiwei; Rizzo, Carmelo J | T32ES007028 | J Am Chem Soc (2004 Sep 15) |
15355100
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2004 |
| Stress sensor triggers conformational response of the integral membrane protein microsomal glutathio ... | Busenlehner, Laura S; Codreanu, Simona G; Holm, Peter J; Bhakat, Priyaranjan; Hebert, Hans; Mor ... | T32ES007028 | Biochemistry (2004 Sep 07) |
15366924
|
2004 |
| Synthesis of the N2-deoxyguanosine adduct of the potent dietary mutagen IQ. | Stover, James S; Rizzo, Carmelo J | T32ES007028 | Org Lett (2004 Dec 23) |
15606116
|
2004 |
| Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4. | Krauser, Joel A; Voehler, Markus; Tseng, Li-Hong; Schefer, Alexandre B; Godejohann, Markus; Gue ... | T32ES007028 | Eur J Biochem (2004 Oct) |
15373842
|
2004 |
| Analysis of unsaturated compounds by Ag+ coordination ionspray mass spectrometry: studies of the for ... | Seal, Jennifer R; Havrilla, Christine M; Porter, Ned A; Hachey, David L | T32ES007028 | J Am Soc Mass Spectrom (2003 Aug) |
12892911
|
2003 |
| Catalytic mechanism of dichloromethane dehalogenase from Methylophilus sp. strain DM11. | Stourman, Nina V; Rose, James H; Vuilleumier, Stephane; Armstrong, Richard N | T32ES007028 | Biochemistry (2003 Sep 23) |
12974641
|
2003 |
| Characterizing the influence of structure and route of exposure on the disposition of dithiocarbamat ... | Johnson, D J; Amarnath, V; Amarnath, K; Valentine, H; Valentine, W M | T32ES007028 | Toxicol Sci (2003 Nov) |
12972631
|
2003 |
| Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogeno ... | VanderVeen, Laurie A; Hashim, Muhammed F; Shyr, Yu; Marnett, Lawrence J | T32ES007028 | Proc Natl Acad Sci U S A (2003 Nov 25) |
14603032
|
2003 |
| Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms. | Fillgrove, Kerry L; Pakhomova, Svetlana; Newcomer, Marcia E; Armstrong, Richard N | T32ES007028 | J Am Chem Soc (2003 Dec 24) |
14677948
|
2003 |
| Mercapturate metabolism of 4-hydroxy-2-nonenal in rat and human cerebrum. | Sidell, Kathrin R; Montine, Kathleen S; Picklo Sr, Matrhew J; Olsen, Sandra J; Amarnath, Ventka ... | T32ES007028 | J Neuropathol Exp Neurol (2003 Feb) |
12578224
|
2003 |
| Parenteral N,N-diethyldithiocarbamate produces segmental demyelination in the rat that is not depend ... | Tonkin, Elizabeth G; Valentine, Holly L; Zimmerman, Lisa J; Valentine, William M | T32ES007028 | Toxicol Appl Pharmacol (2003 Jun 01) |
12781632
|
2003 |
| Catalysis of catechol oxidation by metal-dithiocarbamate complexes in pesticides. | Fitsanakis, Vanessa A; Amarnath, Venkataraman; Moore, Joshua T; Montine, Kathleen S; Zhang, Jin ... | T32ES007028 | Free Radic Biol Med (2002 Dec 15) |
12488139
|
2002 |
| DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6 ... | Nechev, Lubomir V; Kozekov, Ivan D; Brock, Angela K; Rizzo, Carmelo J; Harris, Thomas M | T32ES007028 | Chem Res Toxicol (2002 May) |
12018980
|
2002 |
| Effect of the O6 substituent on misincorporation kinetics catalyzed by DNA polymerases at O(6)-methy ... | Woodside, Adrienne M; Guengerich, F Peter | T32ES007028 | Biochemistry (2002 Jan 22) |
11790127
|
2002 |
| EPR study of substrate binding to the Mn(II) active site of the bacterial antibiotic resistance enzy ... | Smoukov, Stoyan K; Telser, Joshua; Bernat, Bryan A; Rife, Chris L; Armstrong, Richard N; Hoffma ... | T32ES007028 | J Am Chem Soc (2002 Mar 13) |
11878987
|
2002 |
| In vivo and in vitro hepatotoxicity and glutathione interactions of N-methyldithiocarbamate and N,N- ... | Thompson, Rodney W; Valentine, Holly L; Valentine, William M | T32ES007028 | Toxicol Sci (2002 Dec) |
12441372
|
2002 |
| Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting pr ... | Codreanu, Simona G; Ladner, Jane E; Xiao, Gaoyi; Stourman, Nina V; Hachey, David L; Gilliland, ... | T32ES007028 | Biochemistry (2002 Dec 24) |
12484753
|
2002 |
| Microsomal oxidation of tribromoethylene and reactions of tribromoethylene oxide. | Yoshioka, Tadao; Krauser, Joel A; Guengerich, F Peter | T32ES007028 | Chem Res Toxicol (2002 Nov) |
12437332
|
2002 |
| Misincorporation and stalling at O(6)-methylguanine and O(6)-benzylguanine: evidence for inactive po ... | Woodside, Adrienne M; Guengerich, F Peter | T32ES007028 | Biochemistry (2002 Jan 22) |
11790128
|
2002 |
| Molecular recognition at the dimer interface of a class mu glutathione transferase: role of a hydrop ... | Hornby, Judith A T; Codreanu, Simona G; Armstrong, Richard N; Dirr, Heini W | T32ES007028 | Biochemistry (2002 Dec 03) |
12450388
|
2002 |
| Paradoxical enhancement of the toxicity of 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase ... | Liu, Liping; Pegg, Anthony E; Williams, Kevin M; Guengerich, F Peter | T32ES007028 | J Biol Chem (2002 Oct 04) |
12151404
|
2002 |
| Reaction of aflatoxin B(1) oxidation products with lysine. | Guengerich, F Peter; Arneson, Kyle O; Williams, Kevin M; Deng, Zhengwu; Harris, Thomas M | T32ES007028 | Chem Res Toxicol (2002 Jun) |
12067245
|
2002 |
| Structure of the aflatoxin B(1) dialdehyde adduct formed from reaction with methylamine. | Guengerich, F Peter; Voehler, Markus; Williams, Kevin M; Deng, Zhengwu; Harris, Thomas M | T32ES007028 | Chem Res Toxicol (2002 Jun) |
12067246
|
2002 |
| Characterization of nucleoside and DNA adducts formed by S-(1-acetoxymethyl)glutathione and implicat ... | Marsch, G A; Mundkowski, R G; Morris, B J; Manier, M L; Hartman, M K; Guengerich, F P | T32ES007028 | Chem Res Toxicol (2001 May) |
11368561
|
2001 |
| Characterization of the glycosylation sites in cyclooxygenase-2 using mass spectrometry. | Nemeth, J F; Hochgesang Jr, G P; Marnett, L J; Caprioli, R M; Hochensang Jr, G P | T32ES007028 | Biochemistry (2001 Mar 13) |
11258925
|
2001 |
| Coumarin substrates for cytochrome P450 2D6 fluorescence assays. | Nakamura, K; Hanna, I H; Cai, H; Nishimura, Y; Williams, K M; Guengerich, F P | T32ES007028 | Anal Biochem (2001 May 15) |
11355862
|
2001 |
| Cysteine and mercapturate conjugates of oxidized dopamine are in human striatum but only the cystein ... | Sidell, K R; Olson, S J; Ou, J J; Zhang, Y; Amarnath, V; Montine, T J | T32ES007028 | J Neurochem (2001 Nov) |
11701754
|
2001 |
| Diversity in mechanisms of substrate oxidation by cytochrome P450 2D6. Lack of an allosteric role of ... | Hanna, I H; Krauser, J A; Cai, H; Kim, M S; Guengerich, F P | T32ES007028 | J Biol Chem (2001 Oct 26) |
11509577
|
2001 |
| Dopamine thioethers in neurodegeneration. | Sidell, K R; Amamath, V; Montine, T J | T32ES007028 | Curr Top Med Chem (2001 Dec) |
11895128
|
2001 |
| Elementary steps in the acquisition of Mn2+ by the fosfomycin resistance protein (FosA). | Bernat, B A; Armstrong, R N | T32ES007028 | Biochemistry (2001 Oct 23) |
11601996
|
2001 |
| Heparin-binding histidine and lysine residues of rat selenoprotein P. | Hondal, R J; Ma, S; Caprioli, R M; Hill, K E; Burk, R F | T32ES007028 | J Biol Chem (2001 May 11) |
11278668
|
2001 |
| Kinetic analysis of the slow ionization of glutathione by microsomal glutathione transferase MGST1. | Morgenstern, R; Svensson, R; Bernat, B A; Armstrong, R N | T32ES007028 | Biochemistry (2001 Mar 20) |
11258959
|
2001 |
| Kinetic products of linoleate peroxidation: rapid beta-fragmentation of nonconjugated peroxyls. | Tallman, K A; Pratt, D A; Porter, N A | T32ES007028 | J Am Chem Soc (2001 Nov 28) |
11716752
|
2001 |
| Mutagenicity of the malondialdehyde oligomerization products 2-(3'-oxo-1'-propenyl)-malondialdehyde ... | Riggins, J N; Marnett, L J | T32ES007028 | Mutat Res (2001 Oct 18) |
11525918
|
2001 |
| Separation and identification of phospholipid peroxidation products. | Milne, G L; Porter, N A | T32ES007028 | Lipids (2001 Nov) |
11795860
|
2001 |
| Disulfiram produces a non-carbon disulfide-dependent schwannopathy in the rat. | Tonkin, E G; Erve, J C; Valentine, W M | T32ES007028 | J Neuropathol Exp Neurol (2000 Sep) |
11005259
|
2000 |
| p53 regulation of G(2) checkpoint is retinoblastoma protein dependent. | Flatt, P M; Tang, L J; Scatena, C D; Szak, S T; Pietenpol, J A | T32ES007028 | Mol Cell Biol (2000 Jun) |
10825186
|
2000 |
| Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the ... | Johnston, D S; Stone, M P | T32ES007028 | Chem Res Toxicol (2000 Nov) |
11087438
|
2000 |
| Effects of nitric oxide and nitric oxide-derived species on prostaglandin endoperoxide synthase and ... | Goodwin, D C; Landino, L M; Marnett, L J | T32ES007028 | FASEB J (1999 Jul) |
10385604
|
1999 |
| Elucidation of a monovalent cation dependence and characterization of the divalent cation binding si ... | Bernat, B A; Laughlin, L T; Armstrong, R N | T32ES007028 | Biochemistry (1999 Jun 8) |
10360943
|
1999 |
| Explanation of pre-steady-state kinetics and decreased burst amplitude of HIV-1 reverse transcriptas ... | Furge, L L; Guengerich, F P | T32ES007028 | Biochemistry (1999 Apr 13) |
10200170
|
1999 |
| Failure of selenomethionine residues in albumin and immunoglobulin G to protect against peroxynitrit ... | Hondal, R J; Motley, A K; Hill, K E; Burk, R F | T32ES007028 | Arch Biochem Biophys (1999 Nov 1) |
10525286
|
1999 |
| Flavodoxin as a model for the P450-interacting domain of NADPH cytochrome P450 reductase. | Jenkins, C M; Waterman, M R | T32ES007028 | Drug Metab Rev (1999 Feb) |
10065372
|
1999 |
| Kinetics of cytochrome P450 2E1-catalyzed oxidation of ethanol to acetic acid via acetaldehyde. | Bell-Parikh, L C; Guengerich, F P | T32ES007028 | J Biol Chem (1999 Aug 20) |
10446146
|
1999 |
| Reactions of prostaglandin endoperoxide synthase with nitric oxide and peroxynitrite. | Goodwin, D C; Landino, L M; Marnett, L J | T32ES007028 | Drug Metab Rev (1999 Feb) |
10065376
|
1999 |
| Expression of eukaryotic cytochromes P450 in E. coli. | Jenkins, C M; Pikuleva, I; Waterman, M R | T32ES007028 | Methods Mol Biol (1998) |
14577229
|
1998 |
| Mechanism of microsomal epoxide hydrolase. Semifunctional site-specific mutants affecting the alkyla ... | Laughlin, L T; Tzeng, H F; Lin, S; Armstrong, R N | T32ES007028 | Biochemistry (1998 Mar 3) |
9485441
|
1998 |
| Mechanistic imperative for the evolution of a metalloglutathione transferase of the vicinal oxygen c ... | Laughlin, L T; Bernat, B A; Armstrong, R N | T32ES007028 | Chem Biol Interact (1998 Apr 24) |
9679542
|
1998 |
| Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arres ... | Scatena, C D; Stewart, Z A; Mays, D; Tang, L J; Keefer, C J; Leach, S D; Pietenpol, J A | T32ES007028 | J Biol Chem (1998 Nov 13) |
9804855
|
1998 |
| NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble micros ... | Jenkins, C M; Waterman, M R | T32ES007028 | Biochemistry (1998 Apr 28) |
9558349
|
1998 |
| Pre-steady-state kinetics of nucleotide insertion following 8-oxo-7,8-dihydroguanine base pair misma ... | Furge, L L; Guengerich, F P | T32ES007028 | Biochemistry (1998 Mar 10) |
9521678
|
1998 |
| Release of carbon disulfide is a contributing mechanism in the axonopathy produced by N,N-diethyldit ... | Johnson, D J; Graham, D G; Amarnath, V; Amarnath, K; Valentine, W M | T32ES007028 | Toxicol Appl Pharmacol (1998 Feb) |
9473537
|
1998 |
| Twenty years of biochemistry of human P450s: purification, expression, mechanism, and relevance to d ... | Guengerich, F P; Hosea, N A; Parikh, A; Bell-Parikh, L C; Johnson, W W; Gillam, E M; Shimada, ... | T32ES007028 | Drug Metab Dispos (1998 Dec) |
9860923
|
1998 |
| Analysis of nucleotide insertion and extension at 8-oxo-7,8-dihydroguanine by replicative T7 polymer ... | Furge, L L; Guengerich, F P | T32ES007028 | Biochemistry (1997 May 27) |
9174365
|
1997 |
| Escherichia coli flavodoxin sepharose as an affinity resin for cytochromes P450 and use to identify ... | Jenkins, C M; Pikuleva, I; Kagawa, N; Waterman, M R | T32ES007028 | Arch Biochem Biophys (1997 Nov 1) |
9344469
|
1997 |
| Fosfomycin resistance protein (FosA) is a manganese metalloglutathione transferase related to glyoxa ... | Bernat, B A; Laughlin, L T; Armstrong, R N | T32ES007028 | Biochemistry (1997 Mar 18) |
9115979
|
1997 |
| Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endo ... | Landino, L M; Crews, B C; Gierse, J K; Hauser, S D; Marnett, L J | T32ES007028 | J Biol Chem (1997 Aug 22) |
9261177
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1997 |
| Repair of propanodeoxyguanosine by nucleotide excision repair in vivo and in vitro. | Johnson, K A; Fink, S P; Marnett, L J | T32ES007028 | J Biol Chem (1997 Apr 25) |
9111054
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1997 |
| Effects of cysteine-to-serine mutations on structural and functional properties of prostaglandin end ... | Smith, C J; Marnett, L J | T32ES007028 | Arch Biochem Biophys (1996 Nov 15) |
8914931
|
1996 |
| Identification of retained N-formylmethionine in bacterial recombinant mammalian cytochrome P450 pro ... | Dong, M S; Bell, L C; Guo, Z; Phillips, D R; Blair, I A; Guengerich, F P | T32ES007028 | Biochemistry (1996 Aug 6) |
8756465
|
1996 |
| Multiple forms of selenoprotein P in rat plasma. | Chittum, H S; Himeno, S; Hill, K E; Burk, R F | T32ES007028 | Arch Biochem Biophys (1996 Jan 1) |
8554336
|
1996 |
| Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynth ... | Landino, L M; Crews, B C; Timmons, M D; Morrow, J D; Marnett, L J | T32ES007028 | Proc Natl Acad Sci U S A (1996 Dec 24) |
8986765
|
1996 |
| Steady-state and pre-steady-state kinetic analysis of dNTP insertion opposite 8-oxo-7,8-dihydroguani ... | Lowe, L G; Guengerich, F P | T32ES007028 | Biochemistry (1996 Jul 30) |
8703958
|
1996 |
| The measurement of 2-thiothiazolidine-4-carboxylic acid as an index of the in vivo release of CS2 by ... | Johnson, D J; Graham, D G; Amarnath, V; Amarnath, K; Valentine, W M | T32ES007028 | Chem Res Toxicol (1996 Jul-Aug) |
8828929
|
1996 |
| Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse em ... | Keeney, D S; Jenkins, C M; Waterman, M R | T32ES007028 | Endocrinology (1995 Nov) |
7588219
|
1995 |
| Expression of cytochrome P450 2D6 in Escherichia coli, purification, and spectral and catalytic char ... | Gillam, E M; Guo, Z; Martin, M V; Jenkins, C M; Guengerich, F P | T32ES007028 | Arch Biochem Biophys (1995 Jun 01) |
7786040
|
1995 |
| Liver and kidney necrosis in selenium-deficient rats depleted of glutathione. | Burk, R F; Hill, K E; Awad, J A; Morrow, J D; Lyons, P R | T32ES007028 | Lab Invest (1995 Jun) |
7783430
|
1995 |
| Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes. | Bauer, E; Guo, Z; Ueng, Y F; Bell, L C; Zeldin, D; Guengerich, F P | T32ES007028 | Chem Res Toxicol (1995 Jan-Feb) |
7703357
|
1995 |
| Pathogenesis of diquat-induced liver necrosis in selenium-deficient rats: assessment of the roles of ... | Burk, R F; Hill, K E; Awad, J A; Morrow, J D; Kato, T; Cockell, K A; Lyons, P R | T32ES007028 | Hepatology (1995 Feb) |
7843731
|
1995 |
| Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the co ... | Johnston, D S; Stone, M P | T32ES007028 | Biochemistry (1995 Oct 31) |
7578001
|
1995 |
| The chemistry of lipid alkoxyl radicals and their role in metal-amplified lipid peroxidation. | Marnett, L J; Wilcox, A L | T32ES007028 | Biochem Soc Symp (1995) |
8660404
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1995 |
| Detection and localization of lipid peroxidation in selenium- and vitamin E-deficient rats using F2- ... | Awad, J A; Morrow, J D; Hill, K E; Roberts 2nd, L J; Burk, R F | T32ES007028 | J Nutr (1994 Jun) |
8207538
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1994 |
| Detection of the major urinary metabolite of prostaglandin D2 in the circulation: demonstration of e ... | Awad, J A; Morrow, J D; Roberts 2nd, L J | T32ES007028 | J Allergy Clin Immunol (1994 May) |
8182221
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1994 |
| Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxid ... | Awad, J A; Burk, R F; Roberts 2nd, L J | T32ES007028 | J Pharmacol Exp Ther (1994 Sep) |
7932197
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1994 |
| Flavodoxin and NADPH-flavodoxin reductase from Escherichia coli support bovine cytochrome P450c17 hy ... | Jenkins, C M; Waterman, M R | T32ES007028 | J Biol Chem (1994 Nov 04) |
7961651
|
1994 |
| Mechanisms of formation of 1,N6-ethenoadenine, 3,N4-ethenocytosine, 1,N2-ethenoguanine and N2,3-ethe ... | Persmark, M; Humphreys, W G; Okazaki, O; Raney, V M; Guengerich, F P | T32ES007028 | IARC Sci Publ (1994) |
7806335
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1994 |
| Spectroscopic and thermodynamic characterization of the interaction of N7-guanyl thioether derivativ ... | Persmark, M; Guengerich, F P | T32ES007028 | Biochemistry (1994 Jul 26) |
8038155
|
1994 |
| Formation of 1,N2- and N2,3-ethenoguanine from 2-halooxiranes: isotopic labeling studies and isolati ... | Guengerich, F P; Persmark, M; Humphreys, W G | T32ES007028 | Chem Res Toxicol (1993 Sep-Oct) |
8292741
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1993 |
| Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine ... | Awad, J A; Morrow, J D; Takahashi, K; Roberts 2nd, L J | T32ES007028 | J Biol Chem (1993 Feb 25) |
8440704
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1993 |
| N-nitroso-N-methylvinylamine: reaction of the epoxide with guanyl and adenyl moieties to yield adduc ... | Okazaki, O; Persmark, M; Guengerich, F P | T32ES007028 | Chem Res Toxicol (1993 Mar-Apr) |
8477007
|
1993 |
| Polyunsaturated fatty acid alkoxyl radicals exist as carbon-centered epoxyallylic radicals: a key st ... | Wilcox, A L; Marnett, L J | T32ES007028 | Chem Res Toxicol (1993 Jul-Aug) |
8374035
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1993 |
| Simplification of the mass spectrometric assay for the major urinary metabolite of prostaglandin D2. | Awad, J A; Morrow, J D; Roberts 2nd, L J | T32ES007028 | J Chromatogr (1993 Jul 23) |
8376525
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1993 |
| Site-directed mutagenesis of the NH2 terminus of T4 endonuclease V. The position of the alpha NH2 mo ... | Schrock 3rd, R D; Lloyd, R S | T32ES007028 | J Biol Chem (1993 Jan 15) |
8419366
|
1993 |
| Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzyme ... | Guengerich, F P; Shimada, T; Raney, K D; Yun, C H; Meyer, D J; Ketterer, B; Harris, T M; Groo ... | T32ES007028 | Environ Health Perspect (1992 Nov) |
1486866
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1992 |
| Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride ... | Morrow, J D; Awad, J A; Kato, T; Takahashi, K; Badr, K F; Roberts 2nd, L J; Burk, R F | T32ES007028 | J Clin Invest (1992 Dec) |
1469101
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1992 |
| A 1H NMR probe for mobility in the reactive center loops of serpins: spin-echo studies of native and ... | Hood, D B; Gettins, P | T32ES007028 | Biochemistry (1991 Sep 17) |
1892818
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1991 |
| Reductive methylation of the amino terminus of endonuclease V eradicates catalytic activities. Evide ... | Schrock 3rd, R D; Lloyd, R S | T32ES007028 | J Biol Chem (1991 Sep 15) |
1894643
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1991 |
| Selective metal binding to Cys-78 within endonuclease V causes an inhibition of catalytic activities ... | Prince, M A; Friedman, B; Gruskin, E A; Schrock 3rd, R D; Lloyd, R S | T32ES007028 | J Biol Chem (1991 Jun 05) |
2037608
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1991 |
| Biological significance of facilitated diffusion in protein-DNA interactions. Applications to T4 end ... | Dowd, D R; Lloyd, R S | T32ES007028 | J Biol Chem (1990 Feb 25) |
2406255
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1990 |
| Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prosta ... | Atsmon, J; Sweetman, B J; Baertschi, S W; Harris, T M; Roberts 2nd, L J | T32ES007028 | Biochemistry (1990 Apr 17) |
2340271
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1990 |
| Biological consequences of a reduction in the non-target DNA scanning capacity of a DNA repair enzym ... | Dowd, D R; Lloyd, R S | T32ES007028 | J Mol Biol (1989 Aug 20) |
2681789
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1989 |
| Carcinogen-nucleic acid interactions: equilibrium binding studies of aflatoxin B1 with the oligodeox ... | Gopalakrishnan, S; Byrd, S; Stone, M P; Harris, T M | T32ES007028 | Biochemistry (1989 Jan 24) |
2496751
|
1989 |
| Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccha ... | Brian, W R; Srivastava, P K; Umbenhauer, D R; Lloyd, R S; Guengerich, F P | T32ES007028 | Biochemistry (1989 Jun 13) |
2669966
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1989 |
| Mechanistic aspects of the dithiocarbamate-induced mobilization of cadmium. | Topping, R J; Jones, M M; Gale, G R; Smith, A B | T32ES007028 | J Inorg Biochem (1989 Jun) |
2547894
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1989 |
| Site-directed mutagenesis of the T4 endonuclease V gene: the role of arginine-3 in the target search ... | Dowd, D R; Lloyd, R S | T32ES007028 | Biochemistry (1989 Oct 31) |
2690947
|
1989 |
| Non-Watson-Crick structures in oligodeoxynucleotides: self-association of d(TpCpGpA) stabilized at a ... | Topping, R J; Stone, M P; Brush, C K; Harris, T M | T32ES007028 | Biochemistry (1988 Sep 20) |
3207671
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1988 |
| Verrucofortine, a major metabolite of Penicillium verrucosum var. cyclopium, the fungus that produce ... | Hodge, R P; Harris, C M; Harris, T M | T32ES007028 | J Nat Prod (1988 Jan-Feb) |
3373229
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1988 |
| Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts. | Guengerich, F P; Peterson, L A; Cmarik, J L; Koga, N; Inskeep, P B | T32ES007028 | Environ Health Perspect (1987 Dec) |
3329096
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1987 |
| Efficient screening of recombinant DNA junctions afforded by probing with synthetic "bridge" oligonu ... | Recinos 3rd, A; Lloyd, R S | T32ES007028 | Biochem Biophys Res Commun (1986 Jul 31) |
3017346
|
1986 |
| A convenient assay for mephenytoin 4-hydroxylase activity of human liver microsomal cytochrome P-450 ... | Shimada, T; Shea, J P; Guengerich, F P | T32ES007028 | Anal Biochem (1985 May 15) |
4025815
|
1985 |
| Characterization of the enzymatic and nonenzymatic peroxidative degradation of iron porphyrins and c ... | Schaefer, W H; Harris, T M; Guengerich, F P | T32ES007028 | Biochemistry (1985 Jun 18) |
3927975
|
1985 |
| Phosphorylation of DNA topoisomerase II by casein kinase II: modulation of eukaryotic topoisomerase ... | Ackerman, P; Glover, C V; Osheroff, N | T32ES007028 | Proc Natl Acad Sci U S A (1985 May) |
2987912
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1985 |
| Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases ... | Inskeep, P B; Guengerich, F P | T32ES007028 | Carcinogenesis (1984 Jun) |
6373044
|
1984 |
| Toxicology of thiono-sulfur compounds. | Neal, R A; Halpert, J | T32ES007028 | Annu Rev Pharmacol Toxicol (1982) |
7044288
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1982 |
| Cytochrome P-450-dependent metabolism of 1,1,2,2-tetrachloroethane to dichloroacetic acid in vitro. | Halpert, J; Neal, R A | T32ES007028 | Biochem Pharmacol (1981 Jun 01) |
7271831
|
1981 |
| Identification of the major protein adduct formed in rat liver after thioacetamide administration. | Dyroff, M C; Neal, R A | T32ES007028 | Cancer Res (1981 Sep) |
6790164
|
1981 |
| Inactivation of rat liver cytochrome P-450 by the suicide substrates parathion and chloramphenicol. | Halpert, J; Neal, R A | T32ES007028 | Drug Metab Rev (1981) |
7040015
|
1981 |
| Mutagenicity testing of 2,3,7,8-tetrachlordibenzo-p-dioxin in histidine auxotrophs of Salmonella typ ... | Geiger, L E; Neal, R A | T32ES007028 | Toxicol Appl Pharmacol (1981 Jun 15) |
7020158
|
1981 |
| Syncytiotrophoblast membrane vesicles: a model for examining the human placental cholinergic system. | Fant, M E; Harbison, R D | T32ES007028 | Teratology (1981 Oct) |
7336361
|
1981 |
| Tissue distribution, excretion, and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the ... | Olson, J R; Gasiewicz, T A; Neal, R A | T32ES007028 | Toxicol Appl Pharmacol (1980 Oct) |
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1980 |