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Who We Fund: Publication Detail

Project Title: MULTIDISCIPLINARY TRAINING IN ENVIRONMENTAL TOXICOLOGY
PI: Lapres, John J
Institution: Michigan State University
Grant Number: T32ES007255

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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Associations of urinary non-persistent endocrine disrupting chemical biomarkers with early-to-mid pr ...   Ryva, Brad A; Pacyga, Diana C; Anderson, Kaitlyn Y; Calafat, Antonia M; Whalen, Jason; Aung, M ... P30ES007048, R01ES032227, R01ES032227, T32ES007255 Environ Int (2024 Jan) 38219543 Exiting the NIEHS site 2024 
Inhibition of the urea cycle by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin in ...   Cholico, Giovan N; Fling, Russell R; Sink, Warren J; Nault, Rance; Zacharewski, Tim P42ES004911, R01ES029541, T32ES007255 J Biol Chem (2024 Jan) 38013089 Exiting the NIEHS site 2024 
Adipocyte-derived kynurenine stimulates malignant transformation of mammary epithelial cells through ...   Diedrich, Jonathan D; Gonzalez-Pons, Romina; Medeiros, Hyllana C D; Ensink, Elliot; Liby, Karen ... R01ES030695, R01ES030695, T32ES007255 Biochem Pharmacol (2023 Oct) 37625554 Exiting the NIEHS site 2023 
Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mo ...   Cholico, Giovan N; Orlowska, Karina; Fling, Russell R; Sink, Warren J; Zacharewski, Nicholas A; ... P42ES004911, R01ES029541, T32ES007255 Sci Rep (2023 Mar 13) 36914879 Exiting the NIEHS site 2023 
Cystine/Glutamate Xc- Antiporter Induction Compensates for Transsulfuration Pathway Repression by 2, ...   Orlowska, Karina; Fling, Russ R; Nault, Rance; Schilmiller, Anthony L; Zacharewski, Timothy R P42ES004911, R01ES029541, T32ES007255 Chem Res Toxicol (2023 Jun 19) 37184393 Exiting the NIEHS site 2023 
Mycotoxins were not associated with environmental enteropathy in a cohort of Tanzanian children.   Chen, Chen; Patil, Crystal L; Mduma, Estomih R; Groopman, John D; Riley, Ronald T; Wu, Felicia T32ES007255 Risk Anal (2023 Apr) 35618664 Exiting the NIEHS site 2023 
Non-Toxicological Role of Aryl Hydrocarbon Receptor in Obesity-Associated Multiple Myeloma Cell Grow ...   Diedrich, Jonathan D; Cole, Craig E; Pianko, Matthew J; Colacino, Justin A; Bernard, Jamie J P30ES017885, R01ES030695, R01ES030695, T32ES007255 Cancers (Basel) (2023 Nov 01) 37958428 Exiting the NIEHS site 2023 
Ovarian volume partially explains associations of phthalate biomarkers with anti-Müllerian hormone a ...   Cinzori, Maria E; Pacyga, Diana C; Babayev, Elnur; Duncan, Francesca E; Li, Zhong; Williams, P ... T32ES007255 Environ Int (2023 Feb) 36724714 Exiting the NIEHS site 2023 
Comparative effects of human-equivalent low, moderate, and high dose oral prednisone intake on autoi ...   Heine, Lauren K; Benninghoff, Abby D; Ross, Elizabeth A; Rajasinghe, Lichchavi D; Wagner, James ... R01ES027353, T32ES007255 Front Immunol (2022) 36341330 Exiting the NIEHS site 2022 
Determinants of urinary phthalate biomarker concentrations in pre- and perimenopausal women with con ...   Ryva, Brad A; Haggerty, Diana K; Pacyga, Diana C; James-Todd, Tamarra; Li, Zhong; Flaws, Jodi ... T32ES007255 Environ Res (2022 Nov) 35952743 Exiting the NIEHS site 2022 
Dioxin-elicited decrease in cobalamin redirects propionyl-CoA metabolism to the β-oxidation-like pat ...   Orlowska, Karina; Fling, Russ R; Nault, Rance; Sink, Warren J; Schilmiller, Anthony L; Zacharew ... P42ES004911, R01ES029541, R01ES033898, T32ES007255 J Biol Chem (2022 Sep) 35931118 Exiting the NIEHS site 2022 
Generative Deep Learning of the Single Cell Dose Response of 2,3,7,8 Tetrachlorodibenzo-p-dioxin in ...   Kana, Omar Z; Nault, Rance; Zacharewski, Timothy; Bhattacharya, Sudin T32ES007255 FASEB J (2022 May) 35553059 Exiting the NIEHS site 2022 
Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver.   Cholico, Giovan N; Nault, Rance; Zacharewski, Tim R P42ES004911, R01ES029541, T32ES007255 Int J Mol Sci (2022 Jan 29) 35163483 Exiting the NIEHS site 2022 
Pharmacokinetic and toxicodynamic concepts in idiosyncratic, drug-induced liver injury.   Roth, Robert A; Kana, Omar; Filipovic, David; Ganey, Patricia E R01ES031937, T32ES007255 Expert Opin Drug Metab Toxicol (2022) 36003040 Exiting the NIEHS site 2022 
Single cell analysis of docosahexaenoic acid suppression of sequential LPS-induced proinflammatory a ...   Wierenga, Kathryn A; Riemers, Frank M; Westendorp, Bart; Harkema, Jack R; Pestka, James J R01ES027353, T32ES007255 Front Immunol (2022) 36405730 Exiting the NIEHS site 2022 
Small Molecule 20S Proteasome Enhancer Regulates MYC Protein Stability and Exhibits Antitumor Activi ...   Njomen, Evert; Vanecek, Allison; Lansdell, Theresa A; Yang, Ya-Ting; Schall, Peter Z; Harris, ... T32ES007255 Biomedicines (2022 Apr 19) 35625675 Exiting the NIEHS site 2022 
Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Dose-Depend ...   Fling, Russell R; Zacharewski, Timothy R P42ES004911, R01ES029541, T32ES007255 Int J Mol Sci (2021 Nov 18) 34830313 Exiting the NIEHS site 2021 
Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor in Mouse ...   Jurgelewicz, Amanda; Dornbos, Peter; Warren, Melanie; Nault, Rance; Arkatkar, Anooj; Lin, Hui; ... P42ES004911, R01ES029541, T32ES007255 Toxicol Sci (2021 May 27) 33720361 Exiting the NIEHS site 2021 
Omega-3 Polyunsaturated Fatty Acid Intervention Against Established Autoimmunity in a Murine Model o ...   Pestka, James J; Akbari, Peyman; Wierenga, Kathryn A; Bates, Melissa A; Gilley, Kristen N; Wagn ... R01ES027353, T32ES007255 Front Immunol (2021) 33897700 Exiting the NIEHS site 2021 
Rapid Induction of Pulmonary Inflammation, Autoimmune Gene Expression, and Ectopic Lymphoid Neogenes ...   Chauhan, Preeti S; Wagner, James G; Benninghoff, Abby D; Lewandowski, Ryan P; Favor, Olivia K; ... R01ES027353, T32ES007255 Front Immunol (2021) 33732257 Exiting the NIEHS site 2021 
Silica Induction of Diverse Inflammatory Proteome in Lungs of Lupus-Prone Mice Quelled by Dietary Do ...   Rajasinghe, Lichchavi D; Bates, Melissa A; Benninghoff, Abby D; Wierenga, Kathryn A; Harkema, J ... R01ES027353, T32ES007255 Front Immunol (2021) 35126352 Exiting the NIEHS site 2021 
Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibit ...   Cholico, Giovan N; Fling, Russell R; Zacharewski, Nicholas A; Fader, Kelly A; Nault, Rance; Zac ... P42ES004911, R01ES029541, T32ES007255 Sci Rep (2021 08 03) 34344994 Exiting the NIEHS site 2021 
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the pro ...   Fling, Russell R; Doskey, Claire M; Fader, Kelly A; Nault, Rance; Zacharewski, Tim R P42ES004911, R01ES029541, T32ES007255 Sci Rep (2020 09 09) 32908189 Exiting the NIEHS site 2020 
An Automated Method To Predict Mouse Gene and Protein Sequences Using Variant Data.   Dornbos, Peter; Arkatkar, Anooj A; LaPres, John J P42ES004911, T32ES007255 G3 (Bethesda) (2020 03 05) 31911484 Exiting the NIEHS site 2020 
Cytochrome P450 Metabolism of Polyunsaturated Fatty Acids and Neurodegeneration.   Sarparast, Morteza; Dattmore, Devon; Alan, Jamie; Lee, Kin Sing Stephen T32ES007255 Nutrients (2020 Nov 16) 33207662 Exiting the NIEHS site 2020 
Hypoxia upregulates Cxcl12 in hepatocytes by a complex mechanism involving hypoxia-inducible factors ...   Strickland, Jenna; Garrison, Domonique; Copple, Bryan L T32ES007255 Cytokine (2020 03) 31951966 Exiting the NIEHS site 2020 
Influence of total western diet on docosahexaenoic acid suppression of silica-triggered lupus flarin ...   Gilley, Kristen N; Wierenga, Kathryn A; Chauhuan, Preeti S; Wagner, James G; Lewandowski, Ryan ... R01ES027353, T32ES007255 PLoS One (2020) 32413078 Exiting the NIEHS site 2020 
Omega-3 Docosahexaenoic Acid (DHA) Impedes Silica-Induced Macrophage Corpse Accumulation by Attenuat ...   Rajasinghe, Lichchavi D; Chauhan, Preeti S; Wierenga, Kathryn A; Evered, Augustus O; Harris, Sh ... R01ES027353, T32ES007255 Front Immunol (2020) 33123123 Exiting the NIEHS site 2020 
Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline sil ...   Rajasinghe, Lichchavi D; Li, Quan-Zhen; Zhu, Chengsong; Yan, Mei; Chauhan, Preeti S; Wierenga, ... R01ES027353, T32ES007255 Autoimmunity (2020 Nov) 32903098 Exiting the NIEHS site 2020 
Requisite Omega-3 HUFA Biomarker Thresholds for Preventing Murine Lupus Flaring.   Wierenga, Kathryn A; Strakovsky, Rita S; Benninghoff, Abby D; Rajasinghe, Lichchavi D; Lock, Ad ... R01ES027353, T32ES007255 Front Immunol (2020) 32973753 Exiting the NIEHS site 2020 
Targeting Cannabinoid Receptor 2 on Peripheral Leukocytes to Attenuate Inflammatory Mechanisms Impli ...   Rizzo, Michael D; Henriquez, Joseph E; Blevins, Lance K; Bach, Anthony; Crawford, Robert B; Kam ... T32ES007255 J Neuroimmune Pharmacol (2020 12) 32409991 Exiting the NIEHS site 2020 
2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in ...   Fader, Kelly A; Nault, Rance; Doskey, Claire M; Fling, Russell R; Zacharewski, Timothy R P42ES004911, T32ES007255 Sci Rep (2019 04 24) 31015483 Exiting the NIEHS site 2019 
An antibiotic depleted microbiome drives severe Campylobacter jejuni-mediated Type 1/17 colitis, Typ ...   Brooks, Phillip T; Bell, Julia A; Bejcek, Christopher E; Malik, Ankit; Mansfield, Linda S T32ES007255 J Neuroimmunol (2019 12 15) 31678855 Exiting the NIEHS site 2019 
Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C ...   Dornbos, Peter; Jurgelewicz, Amanda; Fader, Kelly A; Williams, Kurt; Zacharewski, Timothy R; La ... P42ES004911, T32ES007255 Sci Rep (2019 11 01) 31676775 Exiting the NIEHS site 2019 
Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) crosslinking via tissue transg ...   Poole, L G; Pant, A; Baker, K S; Kopec, A K; Cline-Fedewa, H M; Iismaa, S E; Flick, M J; Luye ... T32ES007255 J Thromb Haemost (2019 Jan) 30415489 Exiting the NIEHS site 2019 
Chronic low-level cadmium exposure in rats affects cytokine production by activated T cells.   Turley, Alexandra E; Zagorski, Joseph W; Kennedy, Rebekah C; Freeborn, Robert A; Bursley, Jenna ... T32ES007255 Toxicol Res (Camb) (2019 Mar 01) 30997022 Exiting the NIEHS site 2019 
Dichotomous Role of Plasmin in Regulation of Macrophage Function after Acetaminophen Overdose.   Roth, Katherine; Strickland, Jenna; Joshi, Nikita; Deng, Meihong; Kennedy, Rebekah C; Rockwell, ... T32ES007255 Am J Pathol (2019 10) 31381887 Exiting the NIEHS site 2019 
Differential Sensitivity of Kupffer Cells and Hepatic Monocyte-Derived Macrophages to Bacterial Lipo ...   Roth, Katherine; Rockwell, Cheryl E; Copple, Bryan L T32ES007255 Clin Exp Gastroenterol Hepatol (2019 Jan-May) 31555773 Exiting the NIEHS site 2019 
Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahe ...   Baker, Kevin S; Kopec, Anna K; Pant, Asmita; Poole, Lauren G; Cline-Fedewa, Holly; Ivkovich, D ... T32ES007255 Arterioscler Thromb Vasc Biol (2019 10) 31412737 Exiting the NIEHS site 2019 
Distinct Subsets of Lateral Hypothalamic Neurotensin Neurons are Activated by Leptin or Dehydration.   Brown, Juliette A; Wright, Anna; Bugescu, Raluca; Christensen, Lyndsay; Olson, David P; Leinnin ... T32ES007255 Sci Rep (2019 02 12) 30755658 Exiting the NIEHS site 2019 
Docosahexaenoic Acid Consumption Impedes Early Interferon- and Chemokine-Related Gene Expression Whi ...   Benninghoff, Abby D; Bates, Melissa A; Chauhan, Preeti S; Wierenga, Kathryn A; Gilley, Kristen ... R01ES027353, T32ES007255 Front Immunol (2019) 31921124 Exiting the NIEHS site 2019 
Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by ...   Wierenga, Kathryn A; Wee, Josephine; Gilley, Kristen N; Rajasinghe, Lichchavi D; Bates, Melissa ... R01ES027353, T32ES007255 Front Immunol (2019) 31616405 Exiting the NIEHS site 2019 
Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throug ...   Benham, Vanessa; Bullard, Blair; Dexheimer, Thomas S; Bernard, Matthew P; Neubig, Richard R; Li ... T32ES007255 Sci Rep (2019 07 16) 31311976 Exiting the NIEHS site 2019 
Imiquimod and interferon-alpha augment monocyte-mediated astrocyte secretion of MCP-1, IL-6 and IP-1 ...   Rizzo, Michael D; Crawford, Robert B; Bach, Anthony; Sermet, Sera; Amalfitano, Andrea; Kaminski ... T32ES007255 J Neuroimmunol (2019 08 15) 31136945 Exiting the NIEHS site 2019 
Lupus, Silica, and Dietary Omega-3 Fatty Acid Interventions.   Wierenga, Kathryn A; Harkema, Jack R; Pestka, James J R01ES027353, T32ES007255 Toxicol Pathol (2019 Dec) 31725357 Exiting the NIEHS site 2019 
Suppression of CpG-ODN-mediated IFNα and TNFα response in human plasmacytoid dendritic cells (pDC) b ...   Henriquez, Joseph E; Crawford, Robert B; Kaminski, Norbert E T32ES007255 Toxicol Appl Pharmacol (2019 04 15) 30807757 Exiting the NIEHS site 2019 
Δ9-Tetrahydrocannabinol Suppresses Monocyte-Mediated Astrocyte Production of Monocyte Chemoattractan ...   Rizzo, Michael D; Crawford, Robert B; Bach, Anthony; Sermet, Sera; Amalfitano, Andrea; Kaminski ... T32ES007255 J Pharmacol Exp Ther (2019 10) 31383729 Exiting the NIEHS site 2019 
A role for FGF2 in visceral adiposity-associated mammary epithelial transformation.   Benham, Vanessa; Chakraborty, Debrup; Bullard, Blair; Bernard, Jamie J T32ES007255 Adipocyte (2018) 29561195 Exiting the NIEHS site 2018 
Characterizing Serpinb2 as a Modulator of TCDD-Induced Suppression of the B Cell.   Dornbos, Peter; Warren, Melanie; Crawford, Robert B; Kaminski, Norbert E; Threadgill, David W; ... P42ES004911, T32ES007255 Chem Res Toxicol (2018 11 19) 30339366 Exiting the NIEHS site 2018 
Comparison of Hepatic NRF2 and Aryl Hydrocarbon Receptor Binding in 2,3,7,8-Tetrachlorodibenzo-p-dio ...   Nault, Rance; Doskey, Claire M; Fader, Kelly A; Rockwell, Cheryl E; Zacharewski, Tim P42ES004911, T32ES007255 Mol Pharmacol (2018 Aug) 29752288 Exiting the NIEHS site 2018 
Dietary Docosahexaenoic Acid Prevents Silica-Induced Development of Pulmonary Ectopic Germinal Cente ...   Bates, Melissa A; Akbari, Peyman; Gilley, Kristen N; Wagner, James G; Li, Ning; Kopec, Anna K; ... R01ES027353, T32ES007255 Front Immunol (2018) 30258439 Exiting the NIEHS site 2018 
Differential effects of the Nrf2 activators tBHQ and CDDO-Im on the early events of T cell activatio ...   Zagorski, Joseph W; Turley, Alexandra E; Freeborn, Robert A; VanDenBerg, Kelly R; Dover, Heathe ... T32ES007255 Biochem Pharmacol (2018 Jan) 29155145 Exiting the NIEHS site 2018 
Exposure to aflatoxin and fumonisin in children at risk for growth impairment in rural Tanzania.   Chen, Chen; Mitchell, Nicole J; Gratz, Jean; Houpt, Eric R; Gong, Yunyun; Egner, Patricia A; G ... T32ES007255 Environ Int (2018 06) 29544138 Exiting the NIEHS site 2018 
HIV-infected cannabis users have lower circulating CD16+ monocytes and IFN-γ-inducible protein 10 le ...   Rizzo, Michael D; Crawford, Robert B; Henriquez, Joseph E; Aldhamen, Yasser A; Gulick, Peter; A ... T32ES007255 AIDS (2018 Feb 20) 29194121 Exiting the NIEHS site 2018 
Incorporating population-level genetic variability within laboratory models in toxicology: From the ...   Dornbos, Peter; LaPres, John J P42ES004911, T32ES007255 Toxicology (2018 Feb 15) 29275117 Exiting the NIEHS site 2018 
Interferon-α-Mediated Activation of T Cells from Healthy and HIV-Infected Individuals Is Suppressed ...   Henriquez, Joseph E; Rizzo, Michael D; Crawford, Robert B; Gulick, Peter; Kaminski, Norbert E T32ES007255 J Pharmacol Exp Ther (2018 Oct) 30026298 Exiting the NIEHS site 2018 
Lateral Hypothalamic Area Neurotensin Neurons Are Required for Control of Orexin Neurons and Energy ...   Brown, Juliette; Sagante, Andrew; Mayer, Thomas; Wright, Anna; Bugescu, Raluca; Fuller, Patric ... T32ES007255 Endocrinology (2018 Sep 01) 30010830 Exiting the NIEHS site 2018 
The Nrf2 activator tBHQ inhibits the activation of primary murine natural killer cells.   Boss, Allison P; Freeborn, Robert A; Duriancik, David M; Kennedy, Rebekah C; Gardner, Elizabeth ... T32ES007255 Food Chem Toxicol (2018 Nov) 30171972 Exiting the NIEHS site 2018 
Aflatoxin exposure during the first 36 months of life was not associated with impaired growth in Nep ...   Mitchell, Nicole J; Hsu, Hui-Husan; Chandyo, Ram Krishna; Shrestha, Binob; Bodhidatta, Ladaporn ... T32ES007255 PLoS One (2017) 28212415 Exiting the NIEHS site 2017 
Chronic aflatoxin exposure in children living in Bhaktapur, Nepal: Extension of the MAL-ED study.   Mitchell, Nicole J; Riley, Ronald T; Egner, Patricia A; Groopman, John D; Wu, Felicia T32ES007255 J Expo Sci Environ Epidemiol (2017 01) 26732375 Exiting the NIEHS site 2017 
Evaluating a Gene-Environment Interaction in Amyotrophic Lateral Sclerosis: Methylmercury Exposure a ...   Bailey, Jordan M; Colón-Rodríguez, Alexandra; Atchison, William D T32ES007255 Curr Environ Health Rep (2017 Jun) 28397096 Exiting the NIEHS site 2017 
Persistent alterations in immune cell populations and function from a single dose of perfluorononano ...   Rockwell, Cheryl E; Turley, Alexandra E; Cheng, Xingguo; Fields, Patrick E; Klaassen, Curtis D T32ES007255 Food Chem Toxicol (2017 Feb) 27939831 Exiting the NIEHS site 2017 
Δ9-Tetrahydrocannabinol Suppresses Secretion of IFNα by Plasmacytoid Dendritic Cells From Healthy an ...   Henriquez, Joseph E; Rizzo, Michael D; Schulz, Matthias A; Crawford, Robert B; Gulick, Peter; K ... T32ES007255 J Acquir Immune Defic Syndr (2017 08 15) 28692581 Exiting the NIEHS site 2017 
Data of enzymatic activities of the electron transport chain and ATP synthase complexes in mouse hep ...   Hwang, Hye Jin; Steidemann, Michelle; Dunivin, Taylor K; Rizzo, Mike; LaPres, John J P42ES004911, T32ES007255 Data Brief (2016 Sep) 27284569 Exiting the NIEHS site 2016 
Data on AHR-dependent changes in the mitochondrial proteome in response to ,3,7,8-tetrachlorodibenzo ...   Hwang, Hye Jin; Dornbos, Peter; LaPres, John J P42ES004911, T32ES007255 Data Brief (2016 Sep) 27331086 Exiting the NIEHS site 2016 
Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fib ...   Nault, Rance; Fader, Kelly A; Ammendolia, Dustin A; Dornbos, Peter; Potter, Dave; Sharratt, Bo ... T32ES007255 Toxicol Sci (2016 Dec) 27562557 Exiting the NIEHS site 2016 
Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 an ...   Brown, Isola A M; McClain, Jonathon L; Watson, Ralph E; Patel, Bhavik A; Gulbransen, Brian D T32ES007255 Cell Mol Gastroenterol Hepatol (2016 Jan 01) 26771001 Exiting the NIEHS site 2016 
Methylmercury-Dependent Increases in Fluo4 Fluorescence in Neonatal Rat Cerebellar Slices Depend on ...   Bradford, Aaron B; Mancini, Jayme D; Atchison, William D T32ES007255 J Pharmacol Exp Ther (2016 Jan) 26514794 Exiting the NIEHS site 2016 
Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-diox ...   Hwang, Hye Jin; Dornbos, Peter; Steidemann, Michelle; Dunivin, Taylor K; Rizzo, Mike; LaPres, ... P42ES004911, T32ES007255 Toxicol Appl Pharmacol (2016 08 01) 27105554 Exiting the NIEHS site 2016 
Modeling the emetic potencies of food-borne trichothecenes by benchmark dose methodology.   Male, Denis; Wu, Wenda; Mitchell, Nicole J; Bursian, Steven; Pestka, James J; Wu, Felicia T32ES007255 Food Chem Toxicol (2016 Aug) 27292944 Exiting the NIEHS site 2016 
Potential economic losses to the US corn industry from aflatoxin contamination.   Mitchell, Nicole J; Bowers, Erin; Hurburgh, Charles; Wu, Felicia T32ES007255 Food Addit Contam Part A Chem Anal Control Expo Risk Assess (2016) 26807606 Exiting the NIEHS site 2016 
Sensitive Assessment of Hippocampal Learning Using Temporally Dissociated Passive Avoidance Task.   Eagle, Andrew L; Wang, Hongbing; Robison, Alfred J T32ES007255 Bio Protoc (2016 Jun 05) 29119127 Exiting the NIEHS site 2016 
Sirtuin-3 Is Expressed by Enteric Neurons but It Does not Play a Major Role in Their Regulation of O ...   Bubenheimer, Rebecca K; Brown, Isola A M; Fried, David E; McClain, Jonathon L; Gulbransen, Bria ... T32ES007255 Front Cell Neurosci (2016) 27047337 Exiting the NIEHS site 2016 
The Influence of Human Interindividual Variability on the Low-Dose Region of Dose-Response Curve Ind ...   Dornbos, Peter; Crawford, Robert B; Kaminski, Norbert E; Hession, Sarah L; LaPres, John J P42ES004911, T32ES007255 Toxicol Sci (2016 Oct) 27473338 Exiting the NIEHS site 2016 
Comparison of the structure, function and autophagic maintenance of mitochondria in nigrostriatal an ...   Hawong, Hae-Young; Patterson, Joseph R; Winner, Brittany M; Goudreau, John L; Lookingland, Keit ... T32ES007255 Brain Res (2015 Oct 05) 26141374 Exiting the NIEHS site 2015 
Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress.   Vialou, Vincent; Thibault, Mackenzie; Kaska, Sophia; Cooper, Sarah; Gajewski, Paula; Eagle, An ... T32ES007255 Neuropharmacology (2015 Dec) 26164345 Exiting the NIEHS site 2015 
Experience-Dependent Induction of Hippocampal ΔFosB Controls Learning.   Eagle, Andrew L; Gajewski, Paula A; Yang, Miyoung; Kechner, Megan E; Al Masraf, Basma S; Kenned ... T32ES007255 J Neurosci (2015 Oct 07) 26446228 Exiting the NIEHS site 2015 
Hypoxia Inducible Factors Modulate Mitochondrial Oxygen Consumption and Transcriptional Regulation o ...   Hwang, Hye Jin; Lynn, Scott G; Vengellur, Ajith; Saini, Yogesh; Grier, Elizabeth A; Ferguson-Mi ... T32ES007255 Biochemistry (2015 Jun 23) 26030260 Exiting the NIEHS site 2015 
Role of Hypoxia-Inducible Factors in the Development of Liver Fibrosis.   Roth, Katherine J; Copple, Bryan L T32ES007255 Cell Mol Gastroenterol Hepatol (2015 Nov) 28210703 Exiting the NIEHS site 2015 
The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells.   Turley, Alexandra E; Zagorski, Joseph W; Rockwell, Cheryl E T32ES007255 Cytokine (2015 Feb) 25484350 Exiting the NIEHS site 2015 
Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1α-depe ...   Mochizuki, Akie; Pace, Aaron; Rockwell, Cheryl E; Roth, Katherine J; Chow, Aaron; O'Brien, Kat ... T32ES007255 J Immunol (2014 Apr 15) 24639359 Exiting the NIEHS site 2014 
Trovafloxacin enhances lipopolysaccharide-stimulated production of tumor necrosis factor-α by macrop ...   Poulsen, Kyle L; Olivero-Verbel, Jesus; Beggs, Kevin M; Ganey, Patricia E; Roth, Robert A T32ES007255 J Pharmacol Exp Ther (2014 Jul) 24817034 Exiting the NIEHS site 2014 
2,3,7,8-TCDD enhances the sensitivity of mice to concanavalin A immune-mediated liver injury.   Fullerton, Aaron M; Roth, Robert A; Ganey, Patricia E P42ES004911, T32ES007255 Toxicol Appl Pharmacol (2013 Jan 15) 23164664 Exiting the NIEHS site 2013 
An IP3R3- and NPY-expressing microvillous cell mediates tissue homeostasis and regeneration in the m ...   Jia, Cuihong; Hayoz, Sebastien; Hutch, Chelsea R; Iqbal, Tania R; Pooley, Apryl E; Hegg, Colle ... T32ES007255 PLoS One (2013) 23516531 Exiting the NIEHS site 2013 
Evaluation of insulin-like growth factor acid-labile subunit as a potential biomarker of effect for ...   Flannery, Brenna M; Amuzie, Chidozie J; Pestka, James J T32ES007255 Toxicology (2013 Feb 08) 23298694 Exiting the NIEHS site 2013 
IL-17A synergistically enhances bile acid-induced inflammation during obstructive cholestasis.   O'Brien, Kate M; Allen, Katryn M; Rockwell, Cheryl E; Towery, Keara; Luyendyk, James P; Copple, ... T32ES007255 Am J Pathol (2013 Nov) 24012680 Exiting the NIEHS site 2013 
o-p'-DDT-mediated uterotrophy and gene expression in immature C57BL/6 mice and Sprague-Dawley rats.   Kwekel, Joshua C; Forgacs, Agnes L; Williams, Kurt J; Zacharewski, Timothy R T32ES007255 Toxicol Appl Pharmacol (2013 Dec 15) 24096037 Exiting the NIEHS site 2013 
Pretreatment with TCDD exacerbates liver injury from Concanavalin A: critical role for NK cells.   Fullerton, Aaron M; Roth, Robert A; Ganey, Patricia E P42ES004911, T32ES007255 Toxicol Sci (2013 Nov) 23970800 Exiting the NIEHS site 2013 
Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and ...   Sparkenbaugh, Erica M; Ganey, Patricia E; Roth, Robert A T32ES007255 Am J Physiol Gastrointest Liver Physiol (2012 Apr) 22223132 Exiting the NIEHS site 2012 
Exposure to an environmental neurotoxicant hastens the onset of amyotrophic lateral sclerosis-like p ...   Johnson, Frank O; Yuan, Yukun; Hajela, Ravindra K; Chitrakar, Alisha; Parsell, Dawn M; Atchison ... T32ES007255 J Pharmacol Exp Ther (2011 Aug) 21586603 Exiting the NIEHS site 2011 
Natural killer cells mediate severe liver injury in a murine model of halothane hepatitis.   Dugan, Christine M; Fullerton, Aaron M; Roth, Robert A; Ganey, Patricia E T32ES007255 Toxicol Sci (2011 Apr) 21245496 Exiting the NIEHS site 2011 
The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity.   Sparkenbaugh, Erica M; Saini, Yogesh; Greenwood, Krista K; LaPres, John J; Luyendyk, James P; C ... T32ES007255 J Pharmacol Exp Ther (2011 Aug) 21576378 Exiting the NIEHS site 2011 
2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated suppression of toll-like receptor stimulated B-lymphocy ...   North, Colin M; Crawford, Robert B; Lu, Haitian; Kaminski, Norbert E P42ES004911, T32ES007255 Toxicol Sci (2010 Jul) 20348231 Exiting the NIEHS site 2010 
A mouse model of severe halothane hepatitis based on human risk factors.   Dugan, Christine M; MacDonald, Allen E; Roth, Robert A; Ganey, Patricia E T32ES007255 J Pharmacol Exp Ther (2010 May) 20124411 Exiting the NIEHS site 2010 
A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cel ...   Appledorn, Daniel M; Aldhamen, Yasser A; Depas, William; Seregin, Sergey S; Liu, Chyong-Jy J; S ... T32ES007255 PLoS One (2010) 20221448 Exiting the NIEHS site 2010 
Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity.   Maddox, Jane F; Amuzie, Chidozie J; Li, Maoxiang; Newport, Sandra W; Sparkenbaugh, Erica; Cuff, ... T32ES007255 J Toxicol Environ Health A (2010) 19953420 Exiting the NIEHS site 2010 
Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatot ...   Liguori, Michael J; Ditewig, Amy C; Maddox, Jane F; Luyendyk, James P; Lehman-McKeeman, Lois D; ... T32ES007255 Int J Mol Sci (2010 Nov 18) 21151465 Exiting the NIEHS site 2010 
Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, ...   Shaw, Patrick J; Ditewig, Amy C; Waring, Jeffrey F; Liguori, Michael J; Blomme, Eric A; Ganey, ... T32ES007255 Toxicol Sci (2009 Jan) 18930950 Exiting the NIEHS site 2009 
Inhalation of cigarette smoke induces regions of altered DNA methylation (RAMs) in SENCAR mouse lung ...   Phillips, Jennifer M; Goodman, Jay I T32ES007255 Toxicology (2009 Jun 16) 19464564 Exiting the NIEHS site 2009 
Involvement of Blimp-1 and AP-1 dysregulation in the 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated su ...   Schneider, Dina; Manzan, Maria A; Yoo, Byung Sun; Crawford, Robert B; Kaminski, Norbert P42ES004911, T32ES007255 Toxicol Sci (2009 Apr) 19237549 Exiting the NIEHS site 2009 
Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA me ...   Phillips, Jennifer M; Goodman, Jay I T32ES007255 Toxicol Sci (2009 Apr) 19233941 Exiting the NIEHS site 2009 
Phenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical ...   Phillips, Jennifer M; Burgoon, Lyle D; Goodman, Jay I T32ES007255 Toxicol Sci (2009 Jun) 19270015 Exiting the NIEHS site 2009 
Simultaneous in vivo time course and dose response evaluation for TCDD-induced impairment of the LPS ...   North, Colin M; Crawford, Robert B; Lu, Haitian; Kaminski, Norbert E P42ES004911, T32ES007255 Toxicol Sci (2009 Nov) 19675145 Exiting the NIEHS site 2009 
Sulindac metabolism and synergy with tumor necrosis factor-alpha in a drug-inflammation interaction ...   Zou, Wei; Beggs, Kevin M; Sparkenbaugh, Erica M; Jones, A Daniel; Younis, Husam S; Roth, Rober ... T32ES007255 J Pharmacol Exp Ther (2009 Oct) 19638570 Exiting the NIEHS site 2009 
TCDD-mediated suppression of the in vitro anti-sheep erythrocyte IgM antibody forming cell response ...   North, Colin M; Kim, Byung-Sam; Snyder, Neil; Crawford, Robert B; Holsapple, Michael P; Kaminsk ... P42ES004911, T32ES007255 Toxicol Sci (2009 Jan) 18948302 Exiting the NIEHS site 2009 
The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression chan ...   Phillips, Jennifer M; Burgoon, Lyle D; Goodman, Jay I T32ES007255 Toxicol Sci (2009 Aug) 19482888 Exiting the NIEHS site 2009 
The role of environmental mercury, lead and pesticide exposure in development of amyotrophic lateral ...   Johnson, Frank O; Atchison, William D T32ES007255 Neurotoxicology (2009 Sep) 19632272 Exiting the NIEHS site 2009 
2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated impairment of B cell differentiation involves dysregula ...   Schneider, Dina; Manzan, Maria A; Crawford, Robert B; Chen, Weimin; Kaminski, Norbert E P42ES004911, T32ES007255 J Pharmacol Exp Ther (2008 Aug) 18483191 Exiting the NIEHS site 2008 
Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivi ...   Springs, Alison E B; Karmaus, Peer W F; Crawford, Robert B; Kaplan, Barbara L F; Kaminski, Norb ... T32ES007255 J Leukoc Biol (2008 Dec) 18791168 Exiting the NIEHS site 2008 
Identification of genes that may play critical roles in phenobarbital (PB)-induced liver tumorigenes ...   Phillips, Jennifer M; Goodman, Jay I T32ES007255 Toxicol Sci (2008 Jul) 18359763 Exiting the NIEHS site 2008 
Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to i ...   Buchweitz, John P; Karmaus, Peer W F; Williams, Kurt J; Harkema, Jack R; Kaminski, Norbert E T32ES007255 J Leukoc Biol (2008 Mar) 18073275 Exiting the NIEHS site 2008 
2,2',4,4'-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated ...   Bezdecny, Steven A; Karmaus, Peer; Roth, Robert A; Ganey, Patricia E P42ES004911, T32ES007255 Toxicol Appl Pharmacol (2007 Jun 15) 17482227 Exiting the NIEHS site 2007 
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury depend ...   Shaw, Patrick J; Hopfensperger, Marie J; Ganey, Patricia E; Roth, Robert A T32ES007255 Toxicol Sci (2007 Nov) 17709330 Exiting the NIEHS site 2007 
Modulation of airway responses to influenza A/PR/8/34 by Delta9-tetrahydrocannabinol in C57BL/6 mice ...   Buchweitz, John P; Karmaus, Peer W F; Harkema, Jack R; Williams, Kurt J; Kaminski, Norbert E T32ES007255 J Pharmacol Exp Ther (2007 Nov) 17726158 Exiting the NIEHS site 2007 
Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylat ...   Phillips, Jennifer M; Yamamoto, Yukio; Negishi, Masahiko; Maronpot, Robert R; Goodman, Jay I T32ES007255 Toxicol Sci (2007 Mar) 17172636 Exiting the NIEHS site 2007 
The role of tumor necrosis factor alpha in lipopolysaccharide/ranitidine-induced inflammatory liver ...   Tukov, Francis F; Luyendyk, James P; Ganey, Patricia E; Roth, Robert A T32ES007255 Toxicol Sci (2007 Nov) 17698507 Exiting the NIEHS site 2007 
Time-dependent airway epithelial and inflammatory cell responses induced by influenza virus A/PR/8/3 ...   Buchweitz, John P; Harkema, Jack R; Kaminski, Norbert E T32ES007255 Toxicol Pathol (2007 Apr) 17487773 Exiting the NIEHS site 2007 
Altered methylation in gene-specific and GC-rich regions of DNA is progressive and nonrandom during ...   Bachman, Ammie N; Curtin, Geoffrey M; Doolittle, David J; Goodman, Jay I T32ES007255 Toxicol Sci (2006 Jun) 16569730 Exiting the NIEHS site 2006 
Atrazine concentrations, gonadal gross morphology and histology in ranid frogs collected in Michigan ...   Murphy, M B; Hecker, M; Coady, K K; Tompsett, A R; Jones, P D; Du Preez, L H; Everson, G J; S ... T32ES007255 Aquat Toxicol (2006 Mar 10) 16300839 Exiting the NIEHS site 2006 
Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitid ...   Luyendyk, James P; Lehman-McKeeman, Lois D; Nelson, David M; Bhaskaran, Vasanthi M; Reilly, Tim ... T32ES007255 J Pharmacol Exp Ther (2006 May) 16401727 Exiting the NIEHS site 2006 
dbZach: A MIAME-compliant toxicogenomic supportive relational database.   Burgoon, Lyle D; Boutros, Paul C; Dere, Edward; Zacharewski, Timothy R P42ES004911, T32ES007255 Toxicol Sci (2006 Apr) 16403854 Exiting the NIEHS site 2006 
Diethanolamine and phenobarbital produce an altered pattern of methylation in GC-rich regions of DNA ...   Bachman, Ammie N; Kamendulis, Lisa M; Goodman, Jay I T32ES007255 Toxicol Sci (2006 Apr) 16396840 Exiting the NIEHS site 2006 
Dioxin induces an estrogen-like, estrogen receptor-dependent gene expression response in the murine ...   Boverhof, Darrell R; Kwekel, Joshua C; Humes, Daryl G; Burgoon, Lyle D; Zacharewski, Timothy R P42ES004911, T32ES007255 Mol Pharmacol (2006 May) 16467188 Exiting the NIEHS site 2006 
Evaluation of the methoxytriazine herbicide prometon using a short-term fathead minnow reproduction ...   Villeneuve, Daniel L; Murphy, Margaret B; Kahl, Michael D; Jensen, Kathleen M; Butterworth, Bri ... T32ES007255 Environ Toxicol Chem (2006 Aug) 16916034 Exiting the NIEHS site 2006 
Identification and characterization of genes susceptible to transcriptional cross-talk between the h ...   Lee, KangAe; Burgoon, Lyle D; Lamb, Laura; Dere, Edward; Zacharewski, Timothy R; Hogenesch, Jo ... P42ES004911, T32ES007255 Chem Res Toxicol (2006 Oct) 17040097 Exiting the NIEHS site 2006 
Induction of cytochrome P4501A in African brown house snake (Lamprophis fuliginosus) primary hepatoc ...   Hecker, Markus; Murphy, Margaret B; Giesy, John P; Hopkins, William A T32ES007255 Environ Toxicol Chem (2006 Feb) 16519311 Exiting the NIEHS site 2006 
Modeling inflammation-drug interactions in vitro: a rat Kupffer cell-hepatocyte coculture system.   Tukov, Francis F; Maddox, Jane F; Amacher, David E; Bobrowski, Walter F; Roth, Robert A; Ganey, ... T32ES007255 Toxicol In Vitro (2006 Dec) 16782301 Exiting the NIEHS site 2006 
Phenobarbital induces progressive patterns of GC-rich and gene-specific altered DNA methylation in t ...   Bachman, Ammie N; Phillips, Jennifer M; Goodman, Jay I T32ES007255 Toxicol Sci (2006 Jun) 16537655 Exiting the NIEHS site 2006 
Plasma steroid hormone concentrations, aromatase activities and GSI in ranid frogs collected from ag ...   Murphy, M B; Hecker, M; Coady, K K; Tompsett, A R; Higley, E B; Jones, P D; Du Preez, L H; So ... T32ES007255 Aquat Toxicol (2006 May 1) 16427146 Exiting the NIEHS site 2006 
Sediment TCDD-EQs and EROD and MROD activities in Ranid frogs from agricultural and nonagricultural ...   Murphy, M B; Hecker, M; Coady, K K; Tompsett, A R; Jones, P D; Newsted, J L; Wong, H L; du Pr ... T32ES007255 Arch Environ Contam Toxicol (2006 Oct) 16788744 Exiting the NIEHS site 2006 
Unique gene expression and hepatocellular injury in the lipopolysaccharide-ranitidine drug idiosyncr ...   Luyendyk, James P; Lehman-McKeeman, Lois D; Nelson, David M; Bhaskaran, Vasanthi M; Reilly, Tim ... T32ES007255 Toxicol Sci (2006 Apr) 16415329 Exiting the NIEHS site 2006 
A cross-species analysis of the rodent uterotrophic program: elucidation of conserved responses and ...   Kwekel, Joshua C; Burgoon, Lyle D; Burt, Jeremy W; Harkema, Jack R; Zacharewski, Timothy R T32ES007255 Physiol Genomics (2005 Nov 17) 16174780 Exiting the NIEHS site 2005 
Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharid ...   Luyendyk, James P; Shaw, Patrick J; Green, Christopher D; Maddox, Jane F; Ganey, Patricia E; Ro ... T32ES007255 J Pharmacol Exp Ther (2005 Sep) 15933155 Exiting the NIEHS site 2005 
Effects of 2,2',4,4'-tetrachlorobiphenyl on granulocytic HL-60 cell function and expression of cyclo ...   Bezdecny, Steven A; Roth, Robert A; Ganey, Patricia E P42ES004911, T32ES007255 Toxicol Sci (2005 Apr) 15673847 Exiting the NIEHS site 2005 
Effects of atrazine on CYP19 gene expression and aromatase activity in testes and on plasma sex ster ...   Hecker, Markus; Park, June-Woo; Murphy, Margaret B; Jones, Paul D; Solomon, Keith R; Van Der Kr ... T32ES007255 Toxicol Sci (2005 Aug) 15901915 Exiting the NIEHS site 2005 
Protocols for the assurance of microarray data quality and process control.   Burgoon, L D; Eckel-Passow, J E; Gennings, C; Boverhof, D R; Burt, J W; Fong, C J; Zacharewski ... P42ES004911, T32ES007255 Nucleic Acids Res (2005) 16272462 Exiting the NIEHS site 2005 
Acute exposure to methylmercury causes Ca2+ dysregulation and neuronal death in rat cerebellar granu ...   Limke, Tobi L; Bearss, Jeremy J; Atchison, William D T32ES007255 Toxicol Sci (2004 Jul) 15141107 Exiting the NIEHS site 2004 
Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: contri ...   Harrigan, George G; LaPlante, Roxanne H; Cosma, Greg N; Cockerell, Gary; Goodacre, Royston; Mad ... T32ES007255 Toxicol Lett (2004 Feb 02) 14687757 Exiting the NIEHS site 2004 
Gene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide an ...   Luyendyk, James P; Mattes, William B; Burgoon, Lyle D; Zacharewski, Timothy R; Maddox, Jane F; ... T32ES007255 Toxicol Sci (2004 Jul) 15084757 Exiting the NIEHS site 2004 
Neutrophils contribute to endotoxin enhancement of allyl alcohol hepatotoxicity.   Kinser, Shawn; Sneed, Rosie; Roth, Robert; Ganey, Patricia T32ES007255 J Toxicol Environ Health A (2004 Jun 25) 15205035 Exiting the NIEHS site 2004 
Reproductive responses of common carp (Cyprinus carpio) exposed in cages to influent of the Las Vega ...   Snyder, Erin M; Snyder, Shane A; Kelly, Kevin L; Gross, Timothy S; Villeneuve, Daniel L; Fitzge ... T32ES007255 Environ Sci Technol (2004 Dec 01) 15597896 Exiting the NIEHS site 2004 
Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposu ...   Luyendyk, James P; Maddox, Jane F; Green, Christopher D; Ganey, Patricia E; Roth, Robert A T32ES007255 Hepatology (2004 Dec) 15565632 Exiting the NIEHS site 2004 
Augmentation of aflatoxin B1 hepatotoxicity by endotoxin: involvement of endothelium and the coagula ...   Luyendyk, James P; Copple, Bryan L; Barton, Charles C; Ganey, Patricia E; Roth, Robert A T32ES007255 Toxicol Sci (2003 Mar) 12604847 Exiting the NIEHS site 2003 
Comparative susceptibility of B cells with different lineages to cytotoxicity and apoptosis inductio ...   Uzarski, Rebecca L; Pestka, James J T32ES007255 J Toxicol Environ Health A (2003 Nov 28) 14710595 Exiting the NIEHS site 2003 
Endothelial cell injury and coagulation system activation during synergistic hepatotoxicity from mon ...   Yee, Steven B; Hanumegowda, Umesh M; Copple, Bryan L; Shibuya, Masabumi; Ganey, Patricia E; Rot ... T32ES007255 Toxicol Sci (2003 Jul) 12730616 Exiting the NIEHS site 2003 
Evidence for interactions between intracellular calcium stores during methylmercury-induced intracel ...   Limke, Tobi L; Otero-Montanez, James K L; Atchison, William D T32ES007255 J Pharmacol Exp Ther (2003 Mar) 12604669 Exiting the NIEHS site 2003 
Liver inflammation during monocrotaline hepatotoxicity.   Copple, Bryan L; Ganey, Patricia E; Roth, Robert A T32ES007255 Toxicology (2003 Aug 28) 12927372 Exiting the NIEHS site 2003 
Potentiation of trichothecene-induced leukocyte cytotoxicity and apoptosis by TNF-alpha and Fas acti ...   Uzarski, Rebecca L; Islam, Zahidul; Pestka, James J T32ES007255 Chem Biol Interact (2003 Oct 25) 14597125 Exiting the NIEHS site 2003 
Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver inju ...   Luyendyk, James P; Maddox, Jane F; Cosma, Gregory N; Ganey, Patricia E; Cockerell, Gary L; Roth ... T32ES007255 J Pharmacol Exp Ther (2003 Oct) 12893837 Exiting the NIEHS site 2003 
Relationship of trichothecene structure to COX-2 induction in the macrophage: selective action of ty ...   Moon, Yuseok; Uzarski, Rebecca; Pestka, James J T32ES007255 J Toxicol Environ Health A (2003 Oct 24) 14514436 Exiting the NIEHS site 2003 
Role of neutrophils in the synergistic liver injury from monocrotaline and bacterial lipopolysacchar ...   Yee, Steven B; Hanumegowda, Umesh M; Hotchkiss, Jon A; Ganey, Patricia E; Roth, Robert A T32ES007255 Toxicol Sci (2003 Mar) 12604833 Exiting the NIEHS site 2003 
The role of Kupffer cells and TNF-alpha in monocrotaline and bacterial lipopolysaccharide-induced li ...   Yee, Steven B; Ganey, Patricia E; Roth, Robert A T32ES007255 Toxicol Sci (2003 Jan) 12520082 Exiting the NIEHS site 2003 
Thrombin and protease-activated receptor-1 agonists promote lipopolysaccharide-induced hepatocellula ...   Copple, Bryan L; Moulin, Frederic; Hanumegowda, Umesh M; Ganey, Patricia E; Roth, Robert A T32ES007255 J Pharmacol Exp Ther (2003 May) 12606620 Exiting the NIEHS site 2003 
Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebell ...   Limke, Tobi L; Atchison, William D T32ES007255 Toxicol Appl Pharmacol (2002 Jan 1) 11781080 Exiting the NIEHS site 2002 
Enhancement of allyl alcohol hepatotoxicity by endotoxin requires extrahepatic factors.   Kinser, Shawn; Copple, Bryan L; Roth, Robert A; Ganey, Patricia E T32ES007255 Toxicol Sci (2002 Oct) 12377996 Exiting the NIEHS site 2002 
Gestational and lactational exposure of male mice to diethylstilbestrol causes long-term effects on ...   Fielden, Mark R; Halgren, Robert G; Fong, Cora J; Staub, Christophe; Johnson, Larry; Chou, Kar ... T32ES007255 Endocrinology (2002 Aug) 12130571 Exiting the NIEHS site 2002 
Assessment of clone identity and sequence fidelity for 1189 IMAGE cDNA clones.   Halgren, R G; Fielden, M R; Fong, C J; Zacharewski, T R T32ES007255 Nucleic Acids Res (2001 Jan 15) 11139630 Exiting the NIEHS site 2001 
Bacterial lipopolysaccharide enhances aflatoxin B1 hepatotoxicity in rats by a mechanism that depend ...   Barton, C C; Barton, E X; Ganey, P E; Kunkel, S L; Roth, R A T32ES007255 Hepatology (2001 Jan) 11124822 Exiting the NIEHS site 2001 
Hepatic and extrahepatic factors critical for liver injury during lipopolysaccharide exposure.   Moulin, F; Copple, B L; Ganey, P E; Roth, R A T32ES007255 Am J Physiol Gastrointest Liver Physiol (2001 Dec) 11705747 Exiting the NIEHS site 2001 
Bacterial lipopolysaccharide exposure augments aflatoxin B(1)-induced liver injury.   Barton, C C; Hill, D A; Yee, S B; Barton, E X; Ganey, P E; Roth, R A T32ES007255 Toxicol Sci (2000 Jun) 10828277 Exiting the NIEHS site 2000 
Lipopolysaccharide augments aflatoxin B(1)-induced liver injury through neutrophil-dependent and -in ...   Barton, C C; Ganey, P E; Roth, R A T32ES007255 Toxicol Sci (2000 Nov) 11053557 Exiting the NIEHS site 2000 
Malignant transformation of human fibroblast cell strain MSU-1.1 by N-methyl-N-nitrosourea: evidence ...   Boley, S E; McManus, T P; Maher, V M; McCormick, J J T32ES007255 Cancer Res (2000 Aug 1) 10945617 Exiting the NIEHS site 2000 
Synergistic hepatotoxicity from coexposure to bacterial endotoxin and the pyrrolizidine alkaloid mon ...   Yee, S B; Kinser, S; Hill, D A; Barton, C C; Hotchkiss, J A; Harkema, J R; Ganey, P E; Roth, ... T32ES007255 Toxicol Appl Pharmacol (2000 Aug 1) 10906281 Exiting the NIEHS site 2000 
Bile duct epithelial cells exposed to alpha-naphthylisothiocyanate produce a factor that causes neut ...   Hill, D A; Jean, P A; Roth, R A T32ES007255 Toxicol Sci (1999 Jan) 10048160 Exiting the NIEHS site 1999 
In vitro culture of microdissected rat nasal airway tissues.   Fanucchi, M V; Harkema, J R; Plopper, C G; Hotchkiss, J A T32ES007255 Am J Respir Cell Mol Biol (1999 Jun) 10340947 Exiting the NIEHS site 1999 
Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in muscle and eggs of salmonid f ...   Giesy, J P; Kannan, K; Kubitz, J A; Williams, L L; Zabik, M J P42ES004911, T32ES007255 Arch Environ Contam Toxicol (1999 May) 10227863 Exiting the NIEHS site 1999 
The catalytic mechanism of the glutathione-dependent dehydroascorbate reductase activity of thioltra ...   Washburn, M P; Wells, W W T32ES007255 Biochemistry (1999 Jan 5) 9890907 Exiting the NIEHS site 1999 
Thioltransferase overexpression increases resistance of MCF-7 cells to adriamycin.   Meyer, E B; Wells, W W T32ES007255 Free Radic Biol Med (1999 Mar) 10218667 Exiting the NIEHS site 1999 
Alpha-naphthylisothiocyanate causes neutrophils to release factors that are cytotoxic to hepatocytes ...   Hill, D A; Roth, R A T32ES007255 Toxicol Appl Pharmacol (1998 Jan) 9465276 Exiting the NIEHS site 1998 
Cytotoxicity of naphthylisothiocyanates in rat hepatocyte-neutrophil cocultures.   Jean, P A; Kessel, S L; Hill, D A; Roth, R A T32ES007255 Toxicol Lett (1998 May) 9704817 Exiting the NIEHS site 1998 
Lipopolysaccharide activation of murine splenocytes and splenic B cells increased the expression of ...   Marcus, R S; Holsapple, M P; Kaminski, N E T32ES007255 J Pharmacol Exp Ther (1998 Dec) 9864300 Exiting the NIEHS site 1998 
Glutathione dependent reduction of alloxan to dialuric acid catalyzed by thioltransferase (glutaredo ...   Washburn, M P; Wells, W W T32ES007255 Free Radic Biol Med (1997) 9215802 Exiting the NIEHS site 1997 
Pathways mediating Ca2+ entry in rat cerebellar granule cells following in vitro exposure to methyl ...   Marty, M S; Atchison, W D T32ES007255 Toxicol Appl Pharmacol (1997 Dec) 9439727 Exiting the NIEHS site 1997 
Purification and characterization of a glutathione dependent dehydroascorbate reductase from human e ...   Xu, D P; Washburn, M P; Sun, G P; Wells, W W T32ES007255 Biochem Biophys Res Commun (1996 Apr 5) 8660320 Exiting the NIEHS site 1996 
1-naphthylisothiocyanate-induced elevation of biliary glutathione.   Jean, P A; Bailie, M B; Roth, R A T32ES007255 Biochem Pharmacol (1995 Jan 18) 7840796 Exiting the NIEHS site 1995 
Naphthylisothiocyanate disposition in bile and its relationship to liver glutathione and toxicity.   Jean, P A; Roth, R A T32ES007255 Biochem Pharmacol (1995 Oct 26) 7503798 Exiting the NIEHS site 1995 
Methylmercury-induced elevations in intrasynaptosomal zinc concentrations: an 19F-NMR study.   Denny, M F; Atchison, W D T32ES007255 J Neurochem (1994 Jul) 8207443 Exiting the NIEHS site 1994 
Methylmercury alters intrasynaptosomal concentrations of endogenous polyvalent cations.   Denny, M F; Hare, M F; Atchison, W D T32ES007255 Toxicol Appl Pharmacol (1993 Oct) 7692622 Exiting the NIEHS site 1993 
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