Skip Navigation

Publication Detail

Title: A "diels-alderase" at last.

Authors: Townsend, Craig A

Published In Chembiochem, (2011 Oct 17)

Abstract: Diels this Alder your thinking? Electrocyclization reactions are exceedingly rare in metabolic pathways. Why is this so? Recently a [4+2] cycloaddition catalyzed by a monofunctional "Diels-Alderase" has been characterized. How does a 500-fold rate enhancement shown by this enzyme stack up?

PubMed ID: 21796752 Exiting the NIEHS site

MeSH Terms: Biocatalysis; Chorismate Mutase/metabolism; Cycloaddition Reaction/methods*; Cyclohexanecarboxylic Acids/metabolism; Cyclohexenes/metabolism; Methyltransferases/metabolism; S-Adenosylmethionine/metabolism

to Top