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Your Environment. Your Health.

Publication Detail

Title: TRPA1: An asthma target with a zing.

Authors: Jordt, Sven-Eric

Published In J Exp Med, (2021 Apr 05)

Abstract: Asthma therapy has advanced remarkably; however, a significant number of patients respond poorly to current interventions. Balestrini et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20201637) advance the concept that sensory nerves control inflammation in asthma, demonstrating that a novel inhibitor of TRPA1, a nerve receptor for irritants and reactive endogenous mediators, suppresses inflammation and airway smooth muscle contraction in several preclinical species.

PubMed ID: 33625497 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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