Title: From Enhancers to Keratinocyte Cancers.
Authors: Capell, Brian C
Published In J Invest Dermatol, (2021 05)
Abstract: Epigenetic dysregulation and disruption of gene enhancer networks are both pervasive in human cancers, and yet, their roles in keratinocyte cancers are poorly understood. Utilizing patient samples, Yao et al. (2020) provide an initial framework for understanding the underlying mechanisms by integrating enhancer and transcriptional alterations that occur during the progression of basal cell and squamous cell carcinomas.
PubMed ID: 33888214
MeSH Terms: Carcinoma, Squamous Cell*/genetics; Enhancer Elements, Genetic*/genetics; Epigenomics; Gene Regulatory Networks; Humans; Keratinocytes