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Publication Detail

Title: Recent advances in drug repurposing using machine learning.

Authors: Urbina, Fabio; Puhl, Ana C; Ekins, Sean

Published In Curr Opin Chem Biol, (2021 12)

Abstract: Drug repurposing aims to find new uses for already existing and approved drugs. We now provide a brief overview of recent developments in drug repurposing using machine learning alongside other computational approaches for comparison. We also highlight several applications for cancer using kinase inhibitors, Alzheimer's disease as well as COVID-19.

PubMed ID: 34274565 Exiting the NIEHS site

MeSH Terms: Alzheimer Disease/drug therapy*; Antineoplastic Agents/therapeutic use; Antiviral Agents/therapeutic use; COVID-19/drug therapy*; Clemastine/pharmacology; Computational Biology/methods; Dipyridamole/pharmacology; Drug Repositioning/trends*; Humans; Hydroxychloroquine/pharmacology; Lenalidomide/pharmacology; Machine Learning*; Neoplasms/drug therapy*; Neuroprotective Agents/therapeutic use; Piperazines/pharmacology; Piperidines/pharmacology; Protein Kinase Inhibitors/pharmacology

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