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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Novel Δ8-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals.

Authors: Meehan-Atrash, Jiries; Rahman, Irfan

Published In Chem Res Toxicol, (2022 Jan 17)

Abstract: Cannabis e-cigarettes containing Δ8-tetrahydrocannabinol (Δ8-THC) produced synthetically from hemp-derived cannabidiol (CBD) have recently risen in popularity as a legal means of cannabis consumption, but questions surrounding purity and unlabeled additives have created doubts of their safety. Herein, NMR, GC-MS, and ICP-MS were used to analyze major components of 27 products from 10 brands, and it was determined none of these had accurate Δ8-THC labeling, 11 had unlabeled cutting agents, and all contained reaction side-products including olivetol, Δ4(8)-iso-tetrahydrocannabinol, 9-ethoxyhexahydrocannabinol, Δ9-tetrahydrocannabinol (Δ9-THC), heavy metals, and a novel previously undescribed cannabinoid, iso-tetrahydrocannabifuran.

PubMed ID: 34889611 Exiting the NIEHS site

MeSH Terms: Dronabinol/analogs & derivatives; Dronabinol/chemical synthesis*; Dronabinol/chemistry; Metals, Heavy/chemistry*; Molecular Structure; Nebulizers and Vaporizers

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