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Publication Detail

Title: A tipping point in cancer epidemiology: embracing a life course exposomic framework.

Authors: Wright, Rosalind J; Hanson, Heidi A

Published In Trends Cancer, (2022 Apr)

Abstract: The pathogenesis of multifactorial malignant diseases, with variable onset, severity, and natural history, reflects development-specific exposures and individual responses to these exposures influenced by underlying genetic predisposition. Embedded in life course theory, exposomics provides a framework to more fully elucidate how environmental factors alter cancer risk, disease course, and response to treatment across the lifespan.

PubMed ID: 35181274 Exiting the NIEHS site

MeSH Terms: Environmental Exposure/adverse effects; Humans; Life Change Events*; Neoplasms*/etiology; Neoplasms*/genetics

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