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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Arsenic exposure impairs intestinal stromal cells. | Kellett, Michael P; Jatko, Jordan T; Darling, Caitlin L; Ventrello, Scott W; Bain, Lisa J | R15ES031766, R15ES031766, R15ES031766, R15ES031766 | Toxicol Lett (2022 May 15) |
35378173
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2022 |
Balancing Risks and Benefits of E-Cigarettes in the Real World. | Cohen, Joanna E; Krishnan-Sarin, Suchitra; Eissenberg, Thomas; Gould, Thomas J; Berman, Micah L ... | R15ES032138, R15ES032138 | Am J Public Health (2022 02) |
35080942
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2022 |
Diethylene glycol produces nephrotoxic and neurotoxic effects in female rats. | Jamison, Courtney N; Dayton, Robert D; Latimer, Brian; McKinney, Mary P; Mitchell, Hannah G; Mc ... | R15ES029704, R15ES029704 | Clin Toxicol (Phila) (2022 Mar) |
34278906
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2022 |
Dioxin Disrupts Thyroid Hormone and Glucocorticoid Induction of klf9, a Master Regulator of Frog Met ... | Han, David T; Zhao, Weichen; Powell, Wade H | R15ES011130, R15ES011130 | Toxicol Sci (2022 04 26) |
35172007
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2022 |
Identification of Somatic Mitochondrial DNA Mutations, Heteroplasmy, and Increased Levels of Catenan ... | Young, Matthew J; Sachidanandam, Ravi; Hales, Dale B; Brard, Laurent; Robinson, Kathy; Rahman, ... | R15ES033394, R15ES033394 | Life (Basel) (2022 Apr 09) |
35455053
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2022 |
Increased JUUL Emissions from Initial Puffs after Removing and Reinserting Pod. | Soule, Eric K; Sousan, Sinan; Streuber, Dillon; Fresquez, Sarah E; Mooring, Ronald; Salman, Ro ... | R15ES032138, R15ES032138 | Chem Res Toxicol (2022 03 21) |
35258926
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2022 |
Laboratory Determination of Gravimetric Correction Factors for Real-time Area Measurements of Electr ... | Sousan, Sinan; Pender, Jack; Streuber, Dillon; Haley, Meaghan; Shingleton, Will; Soule, Eric | R15ES032138, R15ES032138 | Aerosol Sci Technol (2022) |
35527743
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2022 |
Lipid Composition of the Cell Membrane Outer Leaflet Regulates Endocytosis of Nanomaterials through ... | Nazemidashtarjandi, Saeed; Sharma, Vishva M; Puri, Vishwajeet; Farnoud, Amir M; Burdick, Monica ... | R15ES030140, R15ES030140 | ACS Nano (2022 02 22) |
35138811
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2022 |
The behavioral effects of gestational and lactational benzo[a]pyrene exposure vary by sex and genoty ... | Honaker, Amanda; Kyntchev, Angela; Foster, Emma; Clough, Katelyn; Hawk, Greg; Asiedu, Emmanuel ... | R15ES030541, R15ES030541 | Neurotoxicol Teratol (2022 Jan-Feb) |
34890772
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2022 |
Are individuals consistent? Endocrine reaction norms under different ecological challenges. | Baldan, Davide; Negash, Mekail; Ouyang, Jenny Q | R15ES030548, R15ES030548 | J Exp Biol (2021 06 15) |
34142697
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2021 |
Biochemical and photochemical mechanisms that produce different UV-induced mutation spectra. | Sugiyama, Tomohiko; Keinard, Brianna; Best, Griffin; Sanyal, Mahima R | R15ES029723, R15ES029723 | Mutat Res (2021 Jul-Dec) |
34563793
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2021 |
CATMoS: Collaborative Acute Toxicity Modeling Suite. | Mansouri, Kamel; Karmaus, Agnes L; Fitzpatrick, Jeremy; Patlewicz, Grace; Pradeep, Prachi; Albe ... | P42ES016465, R01ES031080, R15ES023148, R15ES023148, R43ES031038 | Environ Health Perspect (2021 04) |
33929906
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2021 |
Characterization of Lipid Order and Domain Formation in Model Membranes Using Fluorescence Microscop ... | Fuhrer, Andrew; Farnoud, Amir M | R15ES030140, R15ES030140 | Methods Mol Biol (2021) |
32770512
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2021 |
Construction of a Virtual Opioid Bioprofile: A Data-Driven QSAR Modeling Study to Identify New Analg ... | Jia, Xuelian; Ciallella, Heather L; Russo, Daniel P; Zhao, Linlin; James, Morgan H; Zhu, Hao | P30ES005022, R01ES031080, R15ES023148, R15ES023148 | ACS Sustain Chem Eng (2021 Mar 15) |
34239782
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2021 |
Drosophila Passive Avoidance Behavior as a New Paradigm to Study Associative Aversive Learning. | Pak, Elena S; Murashov, Alexander K | R15ES029673, R15ES029673, R15ES029673, R15ES029673 | J Vis Exp (2021 10 15) |
34723949
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2021 |
Effects of dim artificial light at night on locomotor activity, cardiovascular physiology, and circa ... | Alaasam, Valentina J; Liu, Xu; Niu, Ye; Habibian, Justine S; Pieraut, Simon; Ferguson, Brad S; ... | R15ES030548, R15ES030548 | Environ Pollut (2021 Aug 01) |
33838441
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2021 |
Evidence of potential tobacco industry influence in Tobacco Regulatory Science. | Lee, Joseph G L; Soule, Eric K | R15ES032138, R15ES032138 | Tob Control (2021 Aug 13) |
34389687
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2021 |
Glycogen Synthase Kinase 3 Beta Regulates the Human Aryl Hydrocarbon Receptor Cellular Content and A ... | Yang, Yujie; Chan, William K | R15ES023104, R15ES023104 | Int J Mol Sci (2021 Jun 05) |
34198826
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2021 |
Increased toxicity and retention of perflourooctane sulfonate (PFOS) in humanized CYP2B6-Transgenic ... | Hamilton, Matthew C; Heintz, Melissa M; Pfohl, Marisa; Marques, Emily; Ford, Lucie; Slitt, Ang ... | P42ES027706, R15ES017321, R15ES017321 | Food Chem Toxicol (2021 Jun) |
33838175
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2021 |
Infrared thermography is an effective, noninvasive measure of HPA activation. | Ouyang, Jenny Q; Macaballug, Paul; Chen, Hao; Hodach, Kristiana; Tang, Shelly; Francis, Jacob ... | R15ES030548, R15ES030548 | Stress (2021 09) |
33480292
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2021 |
MEHP induces alteration of mitochondrial function and inhibition of steroid biosynthesis in MA-10 mo ... | Traore, Kassim; More, Prajakta; Adla, Akhil; Dogbey, Godwin; Papadopoulos, Vassilios; Zirkin, ... | R15ES032102, R15ES032102, R15ES032102, R15ES032102 | Toxicology (2021 11) |
34627990
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2021 |
Neurotoxic effects of nephrotoxic compound diethylene glycol. | Jamison, Courtney N; Dayton, Robert D; Latimer, Brian; McKinney, Mary P; Mitchell, Hannah G; Mc ... | R15ES029704, R15ES029704 | Clin Toxicol (Phila) (2021 Sep) |
33475432
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2021 |
Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with ... | Mishra, Rosalin; Yuan, Long; Patel, Hima; Karve, Aniruddha S; Zhu, Haizhou; White, Aaron; Alan ... | R15ES029675, R15ES029675 | Int J Mol Sci (2021 Feb 19) |
33669867
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2021 |
Predictive modeling of estrogen receptor agonism, antagonism, and binding activities using machine- ... | Ciallella, Heather L; Russo, Daniel P; Aleksunes, Lauren M; Grimm, Fabian A; Zhu, Hao | P30ES005022, R01ES031080, R15ES023148, R15ES023148 | Lab Invest (2021 04) |
32778734
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2021 |
Revealing Adverse Outcome Pathways from Public High-Throughput Screening Data to Evaluate New Toxica ... | Ciallella, Heather L; Russo, Daniel P; Aleksunes, Lauren M; Grimm, Fabian A; Zhu, Hao | P30ES005022, R01ES031080, R15ES023148, R15ES023148 | Environ Sci Technol (2021 08 03) |
34304572
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2021 |
The Aryl Hydrocarbon Receptor Undergoes Chaperone-Mediated Autophagy in Triple-Negative Breast Cance ... | Chen, Jinyun; Yang, Yujie; Russu, Wade A; Chan, William K | R15ES023104, R15ES023104 | Int J Mol Sci (2021 Feb 06) |
33562118
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2021 |
The Role of AhR in the Hallmarks of Brain Aging: Friend and Foe. | Ojo, Emmanuel S; Tischkau, Shelley A | R15ES030556, R15ES030556, R15ES030556, R15ES030556 | Cells (2021 10 13) |
34685709
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2021 |
A machine learning approach to estimation of phase diagrams for three-component lipid mixtures. | Aghaaminiha, Mohammadreza; Ghanadian, Sara Akbar; Ahmadi, Ehsan; Farnoud, Amir M | R15ES030140, R15ES030140 | Biochim Biophys Acta Biomembr (2020 09 01) |
32407774
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2020 |
Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling ... | Zhao, Linlin; Ciallella, Heather L; Aleksunes, Lauren M; Zhu, Hao | P30ES005022, R01ES031080, R15ES023148, R15ES023148 | Drug Discov Today (2020 09) |
32663517
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2020 |
Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research. | Neuman, Manuela G; Seitz, Helmut Karl; French, Samuel W; Malnick, Stephen; Tsukamoto, Heidekazu ... | R15ES023685, R15ES023685 | Biomedicines (2020 Mar 18) |
32197424
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2020 |
An aryl hydrocarbon receptor from the caecilian Gymnopis multiplicata suggests low dioxin affinity i ... | Kazzaz, Sarah A; Giani Tagliabue, Sara; Franks, Diana G; Denison, Michael S; Hahn, Mark E; Bona ... | R15ES011130, R15ES011130 | Gen Comp Endocrinol (2020 12 01) |
32858041
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2020 |
Analysis of model PM2.5-induced inflammation and cytotoxicity by the combination of a virtual carbon ... | Liu, Guohong; Yan, Xiliang; Sedykh, Alexander; Pan, Xiujiao; Zhao, Xiaoli; Yan, Bing; Zhu, Ha ... | R15ES023148, R15ES023148 | Ecotoxicol Environ Saf (2020 Mar 15) |
31972454
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2020 |
Big Data and Artificial Intelligence Modeling for Drug Discovery. | Zhu, Hao | R15ES023148, R15ES023148 | Annu Rev Pharmacol Toxicol (2020 01 06) |
31518513
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2020 |
CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskel ... | Salem, Fatema B; Bunner, Wyatt P; Prabhu, Vishwanath V; Kuyateh, Abu-Bakarr; O'Bryant, Collin T ... | R15ES029673, R15ES029673, R15ES029673, R15ES029673 | J Biol Chem (2020 08 07) |
32424038
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2020 |
Construction of a web-based nanomaterial database by big data curation and modeling friendly nanostr ... | Yan, Xiliang; Sedykh, Alexander; Wang, Wenyi; Yan, Bing; Zhu, Hao | P30ES005022, R01ES031080, R15ES023148, R15ES023148 | Nat Commun (2020 05 20) |
32433469
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2020 |
Dugesia japonica is the best suited of three planarian species for high-throughput toxicology screen ... | Ireland, Danielle; Bochenek, Veronica; Chaiken, Daniel; Rabeler, Christina; Onoe, Sumi; Soni, ... | R15ES031354, R15ES031354 | Chemosphere (2020 Aug) |
32298908
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2020 |
Gender differences in diet-induced steatotic disease in Cyp2b-null mice. | Heintz, Melissa M; McRee, Rebecca; Kumar, Ramiya; Baldwin, William S | R15ES017321, R15ES017321 | PLoS One (2020) |
32155178
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2020 |
Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2 ... | St John, Nick; Freedland, Julian; Baldino, Henri; Doyle, Francis; Cera, Cinzia; Begley, Thomas ... | R15ES023685, R15ES023685 | G3 (Bethesda) (2020 11 05) |
32994210
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2020 |
Induction of Eryptosis in Red Blood Cells Using a Calcium Ionophore. | Bigdelou, Parnian; Farnoud, Amir M | R15ES030140, R15ES030140 | J Vis Exp (2020 01 21) |
32065143
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2020 |
Lipid Chemical Structure Modulates the Disruptive Effects of Nanomaterials on Membrane Models. | Nazemidashtarjandi, Saeed; Vahedi, Amid; Farnoud, Amir M | R15ES030140, R15ES030140 | Langmuir (2020 05 12) |
32312045
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2020 |
Loss of membrane asymmetry alters the interactions of erythrocytes with engineered silica nanopartic ... | Bigdelou, Parnian; Vahedi, Amid; Kiosidou, Evangelia; Farnoud, Amir M | R15ES030140, R15ES030140 | Biointerphases (2020 06 29) |
32600052
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2020 |
Mechanism-Driven Read-Across of Chemical Hepatotoxicants Based on Chemical Structures and Biological ... | Zhao, Linlin; Russo, Daniel P; Wang, Wenyi; Aleksunes, Lauren M; Zhu, Hao | P30ES005022, R01ES031080, R15ES023148, R15ES023148 | Toxicol Sci (2020 04 01) |
32073637
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2020 |
Selective Autophagy Maintains the Aryl Hydrocarbon Receptor Levels in HeLa Cells: A Mechanism That I ... | Yang, Yujie; Chan, William K | R15ES023104, R15ES023104 | Int J Mol Sci (2020 May 13) |
32414129
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2020 |
Supplemental taurine during adolescence and early adulthood has sex-specific effects on cognition, b ... | Brown, Josephine; Villalona, Yislain; Weimer, Jamie; Ludwig, Clare Pickering; Hays, Breann T; M ... | R15ES030541, R15ES030541 | Neurotoxicol Teratol (2020 May - Jun) |
32289445
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2020 |
Targeting Dysfunctional Vascular Endothelial Cells Using Immunoliposomes Under Flow Conditions. | Kheradmandi, Mahsa; Ackers, Ian; Burdick, Monica M; Malgor, Ramiro; Farnoud, Amir M | R15ES030140, R15ES030140 | Cell Mol Bioeng (2020 Jun) |
32426057
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2020 |
Advancing Computational Toxicology in the Big Data Era by Artificial Intelligence: Data-Driven and M ... | Ciallella, Heather L; Zhu, Hao | R15ES023148, R15ES023148 | Chem Res Toxicol (2019 04 15) |
30907586
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2019 |
Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced N ... | Rooney, John P; Oshida, Keiyu; Kumar, Ramiya; Baldwin, William S; Corton, J Christopher | R15ES017321, R15ES017321 | Toxicol Sci (2019 01 01) |
30203046
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2019 |
Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis. | Heintz, Melissa M; Kumar, Ramiya; Rutledge, Meredith M; Baldwin, William S | R15ES017321, R15ES017321 | J Nutr Biochem (2019 08) |
31202118
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2019 |
Down-Regulation of p23 in Normal Lung Epithelial Cells Reduces Toxicities From Exposure to Benzo[a]p ... | Chen, Jinyun; Yakkundi, Poonam; Chan, William K | R15ES023104, R15ES023104 | Toxicol Sci (2019 01 01) |
30204910
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2019 |
Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across. | Russo, Daniel P; Strickland, Judy; Karmaus, Agnes L; Wang, Wenyi; Shende, Sunil; Hartung, Thom ... | R15ES023148, R15ES023148 | Environ Health Perspect (2019 04) |
30933541
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2019 |
Novel Experimental Modules to Introduce Students to Nanoparticle Characterization in a Chemical Engi ... | Vahedi, Amid; Farnoud, Amir M | R15ES030140, R15ES030140 | J Chem Educ (2019 Sep 10) |
34045773
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2019 |
Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selec ... | Zhu, Haizhou; Mishra, Rosalin; Yuan, Long; Abdul Salam, Safnas F; Liu, Jing; Gray, George; Ste ... | R15ES029675, R15ES029675 | ChemMedChem (2019 11 20) |
31696673
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2019 |
Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors as a First Ste ... | Baldwin, William S | R15ES017321, R15ES017321 | Nucl Receptor Res (2019) |
31815118
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2019 |
Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance. | Liu, Zhenxing; Tabuloc, Christine A; Xue, Yongbo; Cai, Yao; Mcintire, Pearson; Niu, Ye; Lam, ... | R15ES030548, R15ES030548 | PLoS Genet (2019 10) |
31658266
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2019 |
SUR-8 interacts with PP1-87B to stabilize PERIOD and regulate circadian rhythms in Drosophila. | Xue, Yongbo; Chiu, Joanna C; Zhang, Yong | R15ES030548, R15ES030548 | PLoS Genet (2019 11) |
31710605
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2019 |
tRNA modification and cancer: potential for therapeutic prevention and intervention. | Endres, Lauren; Fasullo, Michael; Rose, Rebecca | R15ES023685, R15ES023685 | Future Med Chem (2019 04) |
30744422
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2019 |
Using a hybrid read-across method to evaluate chemical toxicity based on chemical structure and biol ... | Guo, Yajie; Zhao, Linlin; Zhang, Xiaoyi; Zhu, Hao | R15ES023148, R15ES023148 | Ecotoxicol Environ Saf (2019 Aug 30) |
31004930
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2019 |
Comparing Multiple Machine Learning Algorithms and Metrics for Estrogen Receptor Binding Prediction. | Russo, Daniel P; Zorn, Kimberley M; Clark, Alex M; Zhu, Hao; Ekins, Sean | R15ES023148, R15ES023148 | Mol Pharm (2018 10 01) |
30114914
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2018 |
Cyp2b-Knockdown Mice Poorly Metabolize Corn Oil and Are Age-Dependent Obese. | Damiri, Basma; Baldwin, William S | R15ES017321, R15ES017321 | Lipids (2018 09) |
30421529
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2018 |
Dioxin Exposure Alters Molecular and Morphological Responses to Thyroid Hormone in Xenopus laevis Cu ... | Taft, Justin D; Colonnetta, Megan M; Schafer, Rachel E; Plick, Natalie; Powell, Wade H | R15ES011130, R15ES011130 | Toxicol Sci (2018 01 01) |
29294139
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2018 |
DNA damaging agents trigger the expression of the HML silent mating type locus in Saccharomyces cere ... | Derevensky, Michael; Fasullo, Michael | R15ES023685, R15ES023685 | Mutat Res Genet Toxicol Environ Mutagen (2018 Nov) |
30249477
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2018 |
High fat diet induced obesity is mitigated in Cyp3a-null female mice. | Kumar, Ramiya; Litoff, Elizabeth J; Boswell, W Tyler; Baldwin, William S | R15ES017321, R15ES017321 | Chem Biol Interact (2018 Jun 01) |
29738703
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2018 |
Non-Mammalian Nuclear Receptors: From Evolution to Human Disease. | Gissendanner, Chris R; Baldwin, William S; Schaaf, Marcel J M | R15ES017321, R15ES017321 | Nucl Receptor Res (2018) |
30221173
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2018 |
p23 protects the human aryl hydrocarbon receptor from degradation via a heat shock protein 90-indepe ... | Pappas, Beverly; Yang, Yujie; Wang, Yu; Kim, Kyung; Chung, Hee Jae; Cheung, Michael; Ngo, Kat ... | R15ES023104, R15ES023104 | Biochem Pharmacol (2018 06) |
29555469
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2018 |
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory t ... | Hamm, Jon; Sullivan, Kristie; Clippinger, Amy J; Strickland, Judy; Bell, Shannon; Bhhatarai, B ... | P30ES005022, R15ES023148, R15ES023148 | Toxicol In Vitro (2017 Jun) |
28069485
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2017 |
An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae. | Fasullo, Michael; Freedland, Julian; St John, Nicholas; Cera, Cinzia; Egner, Patricia; Hartog, ... | R15ES023685, R15ES023685 | Environ Mol Mutagen (2017 05) |
28436563
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2017 |
Annotation of the Nuclear Receptors in an Estuarine Fish species, Fundulus heteroclitus. | Baldwin, William S; Boswell, W Tyler; Ginjupalli, Gautam; Litoff, Elizabeth J | R15ES017321, R15ES017321 | Nucl Receptor Res (2017) |
28804711
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2017 |
Both RAD5-dependent and independent pathways are involved in DNA damage-associated sister chromatid ... | Fasullo, Michael T; Sun, Mingzeng | R15ES023685, R15ES023685 | AIMS Genet (2017) |
28596989
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2017 |
CIIPro: a new read-across portal to fill data gaps using public large-scale chemical and biological ... | Russo, Daniel P; Kim, Marlene T; Wang, Wenyi; Pinolini, Daniel; Shende, Sunil; Strickland, Jud ... | P30ES005022, R15ES023148, R15ES023148 | Bioinformatics (2017 02 01) |
28172359
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2017 |
Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-n ... | Kumar, Ramiya; Mota, Linda C; Litoff, Elizabeth J; Rooney, John P; Boswell, W Tyler; Courter, ... | R15ES017321, R15ES017321 | PLoS One (2017) |
28350814
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2017 |
CYP1A1 I462V polymorphism is associated with reduced genotoxicity in yeast despite positive associat ... | Freedland, Julian; Cera, Cinzia; Fasullo, Michael | R15ES023685, R15ES023685 | Mutat Res Genet Toxicol Environ Mutagen (2017 Mar) |
28283091
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2017 |
Elucidation of the Molecular Determinants for Optimal Perfluorooctanesulfonate Adsorption Using a Co ... | Liu, Yin; Su, Gaoxing; Wang, Fei; Jia, Jianbo; Li, Shuhuan; Zhao, Linlin; Shi, Yali; Cai, Ya ... | R15ES023148, R15ES023148 | Environ Sci Technol (2017 Jun 20) |
28537376
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2017 |
Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin al ... | Sengupta, Namrata; Reardon, Delaney C; Gerard, Patrick D; Baldwin, William S | R15ES017321, R15ES017321 | PLoS One (2017) |
28542405
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2017 |
Experimental Errors in QSAR Modeling Sets: What We Can Do and What We Cannot Do. | Zhao, Linlin; Wang, Wenyi; Sedykh, Alexander; Zhu, Hao | P30ES005022, R15ES023148, R15ES023148 | ACS Omega (2017 Jun 30) |
28691113
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2017 |
Predicting Nano-Bio Interactions by Integrating Nanoparticle Libraries and Quantitative Nanostructur ... | Wang, Wenyi; Sedykh, Alexander; Sun, Hainan; Zhao, Linlin; Russo, Daniel P; Zhou, Hongyu; Yan, ... | P30ES005022, R15ES023148, R15ES023148 | ACS Nano (2017 12 26) |
29149552
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2017 |
RNA sequencing indicates that atrazine induces multiple detoxification genes in Daphnia magna and th ... | Schmidt, Allison M; Sengupta, Namrata; Saski, Christopher A; Noorai, Rooksana E; Baldwin, Willi ... | R15ES017321, R15ES017321 | Chemosphere (2017 Dec) |
28968576
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2017 |
Subfunctionalization of Paralogous Aryl Hydrocarbon Receptors from the Frog Xenopus Laevis: Distinct ... | Freeburg, Scott H; Engelbrecht, Eric; Powell, Wade H | R15ES011130, R15ES011130 | Toxicol Sci (2017 02) |
27994169
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2017 |
Toward a systematic exploration of nano-bio interactions. | Bai, Xue; Liu, Fang; Liu, Yin; Li, Cong; Wang, Shenqing; Zhou, Hongyu; Wang, Wenyi; Zhu, Hao ... | P30ES005022, R15ES023148, R15ES023148 | Toxicol Appl Pharmacol (2017 05 15) |
28344110
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2017 |
Accessing the High-Throughput Screening Data Landscape. | Russo, Daniel P; Zhu, Hao | R15ES023148, R15ES023148 | Methods Mol Biol (2016) |
27518633
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2016 |
Analysis of Draize eye irritation testing and its prediction by mining publicly available 2008-2014 ... | Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... | R15ES023148, R15ES023148, T32ES007141 | ALTEX (2016) |
26863293
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2016 |
Analysis of public oral toxicity data from REACH registrations 2008-2014. | Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... | R15ES023148, R15ES023148, T32ES007141 | ALTEX (2016) |
26863198
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2016 |
Analysis of publically available skin sensitization data from REACH registrations 2008-2014. | Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... | R15ES023148, R15ES023148, T32ES007141 | ALTEX (2016) |
26863411
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2016 |
Binding studies using Pichia pastoris expressed human aryl hydrocarbon receptor and aryl hydrocarbon ... | Zheng, Yujuan; Xie, Jinghang; Huang, Xin; Dong, Jin; Park, Miki S; Chan, William K | R15ES023104, R15ES023104 | Protein Expr Purif (2016 06) |
26923060
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2016 |
CIIPro: a new read-across portal to fill data gaps using public large-scale chemical and biological ... | Russo, Daniel P; Kim, Marlene T; Wang, Wenyi; Pinolini, Daniel; Shende, Sunil; Strickland, Jud ... | P30ES005022, R15ES023148, R15ES023148 | Bioinformatics (2016 Oct 14) |
27742693
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2016 |
Curating and Preparing High-Throughput Screening Data for Quantitative Structure-Activity Relationsh ... | Kim, Marlene T; Wang, Wenyi; Sedykh, Alexander; Zhu, Hao | R15ES023148, R15ES023148 | Methods Mol Biol (2016) |
27518634
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2016 |
Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combinin ... | Xiang, Jinbao; Zhang, Zhuoqi; Mu, Yan; Xu, Xianxiu; Guo, Sigen; Liu, Yongjin; Russo, Daniel P ... | P30ES005022, R15ES023148, R15ES023148 | ACS Comb Sci (2016 05 09) |
27082930
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2016 |
From fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin po ... | Mu, Y; Liu, Y; Xiang, J; Zhang, Q; Zhai, S; Russo, D P; Zhu, H; Bai, X; Yan, B | R15ES023148, R15ES023148 | Cell Death Dis (2016 Mar 17) |
26986511
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2016 |
Global analysis of publicly available safety data for 9,801 substances registered under REACH from 2 ... | Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... | R15ES023148, R15ES023148, T32ES007141 | ALTEX (2016) |
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2016 |
Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element ... | Kim, Marlene Thai; Huang, Ruili; Sedykh, Alexander; Wang, Wenyi; Xia, Menghang; Zhu, Hao | P30ES005022, R15ES023148, R15ES023148 | Environ Health Perspect (2016 05) |
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2016 |
Perturbations in polar lipids, starvation survival and reproduction following exposure to unsaturate ... | Sengupta, Namrata; Gerard, Patrick D; Baldwin, William S | R15ES017321, R15ES017321 | Chemosphere (2016 Feb) |
26606184
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2016 |
Predictive Modeling of Estrogen Receptor Binding Agents Using Advanced Cheminformatics Tools and Mas ... | Ribay, Kathryn; Kim, Marlene T; Wang, Wenyi; Pinolini, Daniel; Zhu, Hao | P30ES005022, R15ES023148, R15ES023148 | Front Environ Sci (2016 Mar) |
27642585
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2016 |
Selective suppression of the human aryl hydrocarbon receptor function can be mediated through bindin ... | Ren, Lina; Thompson, John D; Cheung, Michael; Ngo, Katherine; Sung, Sarah; Leong, Scott; Chan, ... | R15ES023104, R15ES023104 | Biochem Pharmacol (2016 May 01) |
26970402
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2016 |
Supporting read-across using biological data. | Zhu, Hao; Bouhifd, Mounir; Donley, Elizabeth; Egnash, Laura; Kleinstreuer, Nicole; Kroese, E D ... | P30ES005022, R15ES023148, R15ES023148, T32ES007141 | ALTEX (2016) |
26863516
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2016 |
Toward Good Read-Across Practice (GRAP) guidance. | Ball, Nicholas; Cronin, Mark T D; Shen, Jie; Blackburn, Karen; Booth, Ewan D; Bouhifd, Mounir; ... | P30ES005022, R15ES023148, R15ES023148, T32ES007141 | ALTEX (2016) |
26863606
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2016 |
An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3 ... | Shoots, Jenny; Fraccalvieri, Domenico; Franks, Diana G; Denison, Michael S; Hahn, Mark E; Bonat ... | R15ES011130, R15ES011130 | Environ Sci Technol (2015 Jun 02) |
25941739
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2015 |
Arachidonic acid enhances reproduction in Daphnia magna and mitigates changes in sex ratios induced ... | Ginjupalli, Gautam K; Gerard, Patrick D; Baldwin, William S | R15ES017321, R15ES017321 | Environ Toxicol Chem (2015 Mar) |
25393616
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2015 |
Developing Enhanced Blood-Brain Barrier Permeability Models: Integrating External Bio-Assay Data in ... | Wang, Wenyi; Kim, Marlene T; Sedykh, Alexander; Zhu, Hao | R15ES023148, R15ES023148 | Pharm Res (2015 Sep) |
25862462
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2015 |
Experimental modulation and computational model of nano-hydrophobicity. | Li, Shuhuan; Zhai, Shumei; Liu, Yin; Zhou, Hongyu; Wu, Jinmei; Jiao, Qing; Zhang, Bin; Zhu, ... | R15ES023148, R15ES023148 | Biomaterials (2015 Jun) |
25818437
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2015 |
Improving both aqueous solubility and anti-cancer activity by assessing progressive lead optimizatio ... | Liu, Yin; Li, Fei; Wu, Ling; Wang, Wenyi; Zhu, Hao; Zhang, Qiu; Zhou, Hongyu; Yan, Bing | R15ES023148, R15ES023148 | Bioorg Med Chem Lett (2015 May 01) |
25827524
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2015 |
Repression of multiple CYP2D genes in mouse primary hepatocytes with a single siRNA construct. | Elraghy, Omaima; Baldwin, William S | R15ES017321, R15ES017321 | In Vitro Cell Dev Biol Anim (2015 Jan) |
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2015 |
The HR96 activator, atrazine, reduces sensitivity of D. magna to triclosan and DHA. | Sengupta, Namrata; Litoff, Elizabeth J; Baldwin, William S | R15ES017321, R15ES017321 | Chemosphere (2015 Jun) |
25747156
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2015 |
Activation of aflatoxin B1 by expression of human CYP1A2 polymorphisms in Saccharomyces cerevisiae. | Fasullo, Michael; Smith, Autumn; Egner, Patricia; Cera, Cinzia | R15ES023685, R15ES023685 | Mutat Res Genet Toxicol Environ Mutagen (2014 Feb) |
24472830
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2014 |
Annotation of the Daphnia magna nuclear receptors: comparison to Daphnia pulex. | Litoff, Elizabeth J; Garriott, Travis E; Ginjupalli, Gautam K; Butler, LaToya; Gay, Claudy; Sco ... | R15ES017321, R15ES017321 | Gene (2014 Nov 15) |
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2014 |
Big data in chemical toxicity research: the use of high-throughput screening assays to identify pote ... | Zhu, Hao; Zhang, Jun; Kim, Marlene T; Boison, Abena; Sedykh, Alexander; Moran, Kimberlee | R15ES023148, R15ES023148 | Chem Res Toxicol (2014 Oct 20) |
25195622
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2014 |
Bisphenol A regulation of testicular endocrine function in male rats is affected by diet. | Nanjappa, Manjunatha K; Ahuja, Manuj; Dhanasekaran, Muralikrishnan; Coleman, Elaine S; Braden, ... | R15ES015886, R15ES015886, R15ES015886, R15ES015886 | Toxicol Lett (2014 Mar 21) |
24472609
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2014 |
Critical evaluation of human oral bioavailability for pharmaceutical drugs by using various cheminfo ... | Kim, Marlene T; Sedykh, Alexander; Chakravarti, Suman K; Saiakhov, Roustem D; Zhu, Hao | R15ES023148, R15ES023148 | Pharm Res (2014 Apr) |
24306326
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2014 |
Design, synthesis and experimental validation of novel potential chemopreventive agents using random ... | Sprague, Brienne; Shi, Qian; Kim, Marlene T; Zhang, Liying; Sedykh, Alexander; Ichiishi, Eiich ... | R15ES023148, R15ES023148 | J Comput Aided Mol Des (2014 Jun) |
24840854
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2014 |
Profiling animal toxicants by automatically mining public bioassay data: a big data approach for com ... | Zhang, Jun; Hsieh, Jui-Hua; Zhu, Hao | R15ES023148, R15ES023148 | PLoS One (2014) |
24950175
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2014 |
Testicular development in male rats is sensitive to a soy-based diet in the neonatal period. | Napier, India D; Simon, Liz; Perry, Devin; Cooke, Paul S; Stocco, Douglas M; Sepehr, Estatira; ... | R15ES015886, R15ES015886, R15ES015886, R15ES015886 | Biol Reprod (2014 Feb) |
24451983
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2014 |
The HR97 (NR1L) group of nuclear receptors: a new group of nuclear receptors discovered in Daphnia s ... | Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S | R15ES017321, R15ES017321 | Gen Comp Endocrinol (2014 Sep 15) |
25092536
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2014 |
Tuning cell autophagy by diversifying carbon nanotube surface chemistry. | Wu, Ling; Zhang, Yi; Zhang, Chengke; Cui, Xuehui; Zhai, Shumei; Liu, Yin; Li, Changlong; Zhu, ... | R15ES023148, R15ES023148 | ACS Nano (2014 Mar 25) |
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2014 |
Discovery of novel antimalarial compounds enabled by QSAR-based virtual screening. | Zhang, Liying; Fourches, Denis; Sedykh, Alexander; Zhu, Hao; Golbraikh, Alexander; Ekins, Sean ... | R15ES023148, R15ES023148 | J Chem Inf Model (2013 Feb 25) |
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2013 |
From QSAR to QSIIR: searching for enhanced computational toxicology models. | Zhu, Hao | R15ES023148, R15ES023148 | Methods Mol Biol (2013) |
23086837
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2013 |
Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux an ... | Sedykh, Alexander; Fourches, Denis; Duan, Jianmin; Hucke, Oliver; Garneau, Michel; Zhu, Hao; B ... | R15ES023148, R15ES023148 | Pharm Res (2013 Apr) |
23269503
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2013 |
Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and ... | Zhang, Liying; Sedykh, Alexander; Tripathi, Ashutosh; Zhu, Hao; Afantitis, Antreas; Mouchlis, ... | R15ES023148, R15ES023148 | Toxicol Appl Pharmacol (2013 Oct 01) |
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2013 |
Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis. | Odio, Camila; Holzman, Sarah A; Denison, Michael S; Fraccalvieri, Domenico; Bonati, Laura; Fran ... | R15ES011130, R15ES011130 | Biochemistry (2013 Mar 12) |
23394719
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2013 |
The time- and age-dependent effects of the juvenile hormone analog pesticide, pyriproxyfen on Daphni ... | Ginjupalli, Gautam K; Baldwin, William S | R15ES017321, R15ES017321 | Chemosphere (2013 Aug) |
23714148
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2013 |
The use of pseudo-equilibrium constant affords improved QSAR models of human plasma protein binding. | Zhu, Xiang-Wei; Sedykh, Alexander; Zhu, Hao; Liu, Shu-Shen; Tropsha, Alexander | R15ES023148, R15ES023148 | Pharm Res (2013 Jul) |
23568522
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2013 |
Daphnia HR96 is a promiscuous xenobiotic and endobiotic nuclear receptor. | Karimullina, Elina; Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S | R15ES017321, R15ES017321 | Aquat Toxicol (2012 Jul 15) |
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2012 |
Induction of cytochrome P450 family 1 mRNAs and activities in a cell line from the frog Xenopus laev ... | Iwamoto, Daniel V; Kurylo, Chad M; Schorling, Kelly M; Powell, Wade H | R15ES011130, R15ES011130 | Aquat Toxicol (2012 Jun 15) |
22446828
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2012 |
Lentiviral-mediated RNAi knockdown yields a novel mouse model for studying Cyp2b function. | Damiri, Basma; Holle, Eric; Yu, Xianzhong; Baldwin, William S | R15ES017321, R15ES017321 | Toxicol Sci (2012 Feb) |
22083726
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2012 |
Predicting chemical ocular toxicity using a combinatorial QSAR approach. | Solimeo, Renee; Zhang, Jun; Kim, Marlene; Sedykh, Alexander; Zhu, Hao | R15ES023148, R15ES023148 | Chem Res Toxicol (2012 Dec 17) |
23148656
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2012 |
The industrial chemical bisphenol A (BPA) interferes with proliferative activity and development of ... | Nanjappa, Manjunatha K; Simon, Liz; Akingbemi, Benson T | R15ES015886, R15ES015886, R15ES015886, R15ES015886 | Biol Reprod (2012 May) |
22302688
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2012 |
Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes ... | Mota, Linda C; Barfield, Christina; Hernandez, Juan P; Baldwin, William S | R15ES017321, R15ES017321 | Toxicol Appl Pharmacol (2011 May 1) |
21376070
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2011 |
Selective imaging and killing of cancer cells with protein-activated near-infrared fluorescing nanop ... | Rungta, Parul; Bandera, Yuriy P; Roeder, Ryan D; Li, Yangchun; Baldwin, William S; Sharma, Dee ... | R15ES017321, R15ES017321 | Macromol Biosci (2011 Jul 07) |
21480531
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2011 |
Constitutive androstane receptor -null mice are sensitive to the toxic effects of parathion: associa ... | Mota, Linda C; Hernandez, Juan P; Baldwin, William S | R15ES017321, R15ES017321 | Drug Metab Dispos (2010 Sep) |
20573718
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2010 |
Developmental exposures of male rats to soy isoflavones impact Leydig cell differentiation. | Sherrill, Jessica D; Sparks, Morgan; Dennis, John; Mansour, Mahmoud; Kemppainen, Barbara W; Bar ... | R15ES015886, R15ES015886, R15ES015886, R15ES015886 | Biol Reprod (2010 Sep) |
20554919
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2010 |
Dose-responsive gene expression changes in juvenile and adult mummichogs (Fundulus heteroclitus) aft ... | Gonzalez, Horacio O; Hu, Jianjun; Gaworecki, Kristen M; Roling, Jonathan A; Baldwin, William S; ... | R15ES017321, R15ES017321 | Mar Environ Res (2010 Aug) |
20451245
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2010 |
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: ... | Van Aggelen, Graham; Ankley, Gerald T; Baldwin, William S; Bearden, Daniel W; Benson, William H ... | R15ES017321, R15ES017321 | Environ Health Perspect (2010 Jan) |
20056575
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2010 |
Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription ... | Hannas, Bethany R; Wang, Ying H; Baldwin, William S; Li, Yangchun; Wallace, Andrew D; LeBlanc, ... | R15ES017321, R15ES017321, T32ES007046 | Gen Comp Endocrinol (2010 Jun 1) |
20346363
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2010 |
Responsiveness of a Xenopus laevis cell line to the aryl hydrocarbon receptor ligands 6-formylindolo ... | Laub, Leo B; Jones, Brian D; Powell, Wade H | R15ES011130, R15ES011130 | Chem Biol Interact (2010 Jan 05) |
19799885
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2010 |
A concentration addition model for the activation of the constitutive androstane receptor by xenobio ... | Baldwin, William S; Roling, Jonathan A | R15ES017321, R15ES017321 | Toxicol Sci (2009 Jan) |
18832183
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2009 |
Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolis ... | Hernandez, J P; Mota, L C; Baldwin, W S | R15ES017321, R15ES017321 | Curr Pharmacogenomics Person Med (2009 Jun 01) |
20871735
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2009 |
Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR). | Hernandez, J P; Mota, L C; Huang, W; Moore, D D; Baldwin, W S | R15ES017321, R15ES017321 | Toxicology (2009 Feb 4) |
19041682
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2009 |
An aryl hydrocarbon receptor repressor from Xenopus laevis: function, expression, and role in dioxin ... | Zimmermann, Anna L; King, Elizabeth A; Dengler, Emelyne; Scogin, Shana R; Powell, Wade H | R15ES011130, R15ES011130 | Toxicol Sci (2008 Jul) |
18385208
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2008 |
Developmental differences in elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during Xenopu ... | Philips, Blythe H; Susman, Thomas C; Powell, Wade H | R15ES011130, R15ES011130 | Mar Environ Res (2006 Jul) |
16697456
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2006 |
Aryl hydrocarbon receptors in the frog Xenopus laevis: two AhR1 paralogs exhibit low affinity for 2, ... | Lavine, Jeremy A; Rowatt, Ashley J; Klimova, Tatyana; Whitington, Aric J; Dengler, Emelyne; Bec ... | R15ES011130, R15ES011130 | Toxicol Sci (2005 Nov) |
15958654
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2005 |
ARNT gene multiplicity in amphibians: characterization of ARNT2 from the frog Xenopus laevis. | Rowatt, Ashley J; DePowell, John J; Powell, Wade H | R15ES011130, R15ES011130 | J Exp Zool B Mol Dev Evol (2003 Dec 15) |
14984034
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2003 |