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Who We Fund: Publications associated with Training And Career Development - AREA (Secondary only)

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 138 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Arsenic exposure impairs intestinal stromal cells.   Kellett, Michael P; Jatko, Jordan T; Darling, Caitlin L; Ventrello, Scott W; Bain, Lisa J R15ES031766, R15ES031766, R15ES031766, R15ES031766 Toxicol Lett (2022 May 15) 35378173 Exiting the NIEHS site 2022 
Balancing Risks and Benefits of E-Cigarettes in the Real World.   Cohen, Joanna E; Krishnan-Sarin, Suchitra; Eissenberg, Thomas; Gould, Thomas J; Berman, Micah L ... R15ES032138, R15ES032138 Am J Public Health (2022 02) 35080942 Exiting the NIEHS site 2022 
Diethylene glycol produces nephrotoxic and neurotoxic effects in female rats.   Jamison, Courtney N; Dayton, Robert D; Latimer, Brian; McKinney, Mary P; Mitchell, Hannah G; Mc ... R15ES029704, R15ES029704 Clin Toxicol (Phila) (2022 Mar) 34278906 Exiting the NIEHS site 2022 
Dioxin Disrupts Thyroid Hormone and Glucocorticoid Induction of klf9, a Master Regulator of Frog Met ...   Han, David T; Zhao, Weichen; Powell, Wade H R15ES011130, R15ES011130 Toxicol Sci (2022 04 26) 35172007 Exiting the NIEHS site 2022 
Identification of Somatic Mitochondrial DNA Mutations, Heteroplasmy, and Increased Levels of Catenan ...   Young, Matthew J; Sachidanandam, Ravi; Hales, Dale B; Brard, Laurent; Robinson, Kathy; Rahman, ... R15ES033394, R15ES033394 Life (Basel) (2022 Apr 09) 35455053 Exiting the NIEHS site 2022 
Increased JUUL Emissions from Initial Puffs after Removing and Reinserting Pod.   Soule, Eric K; Sousan, Sinan; Streuber, Dillon; Fresquez, Sarah E; Mooring, Ronald; Salman, Ro ... R15ES032138, R15ES032138 Chem Res Toxicol (2022 03 21) 35258926 Exiting the NIEHS site 2022 
Laboratory Determination of Gravimetric Correction Factors for Real-time Area Measurements of Electr ...   Sousan, Sinan; Pender, Jack; Streuber, Dillon; Haley, Meaghan; Shingleton, Will; Soule, Eric R15ES032138, R15ES032138 Aerosol Sci Technol (2022) 35527743 Exiting the NIEHS site 2022 
Lipid Composition of the Cell Membrane Outer Leaflet Regulates Endocytosis of Nanomaterials through ...   Nazemidashtarjandi, Saeed; Sharma, Vishva M; Puri, Vishwajeet; Farnoud, Amir M; Burdick, Monica ... R15ES030140, R15ES030140 ACS Nano (2022 02 22) 35138811 Exiting the NIEHS site 2022 
The behavioral effects of gestational and lactational benzo[a]pyrene exposure vary by sex and genoty ...   Honaker, Amanda; Kyntchev, Angela; Foster, Emma; Clough, Katelyn; Hawk, Greg; Asiedu, Emmanuel ... R15ES030541, R15ES030541 Neurotoxicol Teratol (2022 Jan-Feb) 34890772 Exiting the NIEHS site 2022 
Are individuals consistent? Endocrine reaction norms under different ecological challenges.   Baldan, Davide; Negash, Mekail; Ouyang, Jenny Q R15ES030548, R15ES030548 J Exp Biol (2021 06 15) 34142697 Exiting the NIEHS site 2021 
Biochemical and photochemical mechanisms that produce different UV-induced mutation spectra.   Sugiyama, Tomohiko; Keinard, Brianna; Best, Griffin; Sanyal, Mahima R R15ES029723, R15ES029723 Mutat Res (2021 Jul-Dec) 34563793 Exiting the NIEHS site 2021 
CATMoS: Collaborative Acute Toxicity Modeling Suite.   Mansouri, Kamel; Karmaus, Agnes L; Fitzpatrick, Jeremy; Patlewicz, Grace; Pradeep, Prachi; Albe ... P42ES016465, R01ES031080, R15ES023148, R15ES023148, R43ES031038 Environ Health Perspect (2021 04) 33929906 Exiting the NIEHS site 2021 
Characterization of Lipid Order and Domain Formation in Model Membranes Using Fluorescence Microscop ...   Fuhrer, Andrew; Farnoud, Amir M R15ES030140, R15ES030140 Methods Mol Biol (2021) 32770512 Exiting the NIEHS site 2021 
Construction of a Virtual Opioid Bioprofile: A Data-Driven QSAR Modeling Study to Identify New Analg ...   Jia, Xuelian; Ciallella, Heather L; Russo, Daniel P; Zhao, Linlin; James, Morgan H; Zhu, Hao P30ES005022, R01ES031080, R15ES023148, R15ES023148 ACS Sustain Chem Eng (2021 Mar 15) 34239782 Exiting the NIEHS site 2021 
Drosophila Passive Avoidance Behavior as a New Paradigm to Study Associative Aversive Learning.   Pak, Elena S; Murashov, Alexander K R15ES029673, R15ES029673, R15ES029673, R15ES029673 J Vis Exp (2021 10 15) 34723949 Exiting the NIEHS site 2021 
Effects of dim artificial light at night on locomotor activity, cardiovascular physiology, and circa ...   Alaasam, Valentina J; Liu, Xu; Niu, Ye; Habibian, Justine S; Pieraut, Simon; Ferguson, Brad S; ... R15ES030548, R15ES030548 Environ Pollut (2021 Aug 01) 33838441 Exiting the NIEHS site 2021 
Evidence of potential tobacco industry influence in Tobacco Regulatory Science.   Lee, Joseph G L; Soule, Eric K R15ES032138, R15ES032138 Tob Control (2021 Aug 13) 34389687 Exiting the NIEHS site 2021 
Glycogen Synthase Kinase 3 Beta Regulates the Human Aryl Hydrocarbon Receptor Cellular Content and A ...   Yang, Yujie; Chan, William K R15ES023104, R15ES023104 Int J Mol Sci (2021 Jun 05) 34198826 Exiting the NIEHS site 2021 
Increased toxicity and retention of perflourooctane sulfonate (PFOS) in humanized CYP2B6-Transgenic ...   Hamilton, Matthew C; Heintz, Melissa M; Pfohl, Marisa; Marques, Emily; Ford, Lucie; Slitt, Ang ... P42ES027706, R15ES017321, R15ES017321 Food Chem Toxicol (2021 Jun) 33838175 Exiting the NIEHS site 2021 
Infrared thermography is an effective, noninvasive measure of HPA activation.   Ouyang, Jenny Q; Macaballug, Paul; Chen, Hao; Hodach, Kristiana; Tang, Shelly; Francis, Jacob ... R15ES030548, R15ES030548 Stress (2021 09) 33480292 Exiting the NIEHS site 2021 
MEHP induces alteration of mitochondrial function and inhibition of steroid biosynthesis in MA-10 mo ...   Traore, Kassim; More, Prajakta; Adla, Akhil; Dogbey, Godwin; Papadopoulos, Vassilios; Zirkin, ... R15ES032102, R15ES032102, R15ES032102, R15ES032102 Toxicology (2021 11) 34627990 Exiting the NIEHS site 2021 
Neurotoxic effects of nephrotoxic compound diethylene glycol.   Jamison, Courtney N; Dayton, Robert D; Latimer, Brian; McKinney, Mary P; Mitchell, Hannah G; Mc ... R15ES029704, R15ES029704 Clin Toxicol (Phila) (2021 Sep) 33475432 Exiting the NIEHS site 2021 
Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with ...   Mishra, Rosalin; Yuan, Long; Patel, Hima; Karve, Aniruddha S; Zhu, Haizhou; White, Aaron; Alan ... R15ES029675, R15ES029675 Int J Mol Sci (2021 Feb 19) 33669867 Exiting the NIEHS site 2021 
Predictive modeling of estrogen receptor agonism, antagonism, and binding activities using machine- ...   Ciallella, Heather L; Russo, Daniel P; Aleksunes, Lauren M; Grimm, Fabian A; Zhu, Hao P30ES005022, R01ES031080, R15ES023148, R15ES023148 Lab Invest (2021 04) 32778734 Exiting the NIEHS site 2021 
Revealing Adverse Outcome Pathways from Public High-Throughput Screening Data to Evaluate New Toxica ...   Ciallella, Heather L; Russo, Daniel P; Aleksunes, Lauren M; Grimm, Fabian A; Zhu, Hao P30ES005022, R01ES031080, R15ES023148, R15ES023148 Environ Sci Technol (2021 08 03) 34304572 Exiting the NIEHS site 2021 
The Aryl Hydrocarbon Receptor Undergoes Chaperone-Mediated Autophagy in Triple-Negative Breast Cance ...   Chen, Jinyun; Yang, Yujie; Russu, Wade A; Chan, William K R15ES023104, R15ES023104 Int J Mol Sci (2021 Feb 06) 33562118 Exiting the NIEHS site 2021 
The Role of AhR in the Hallmarks of Brain Aging: Friend and Foe.   Ojo, Emmanuel S; Tischkau, Shelley A R15ES030556, R15ES030556, R15ES030556, R15ES030556 Cells (2021 10 13) 34685709 Exiting the NIEHS site 2021 
A machine learning approach to estimation of phase diagrams for three-component lipid mixtures.   Aghaaminiha, Mohammadreza; Ghanadian, Sara Akbar; Ahmadi, Ehsan; Farnoud, Amir M R15ES030140, R15ES030140 Biochim Biophys Acta Biomembr (2020 09 01) 32407774 Exiting the NIEHS site 2020 
Advancing computer-aided drug discovery (CADD) by big data and data-driven machine learning modeling ...   Zhao, Linlin; Ciallella, Heather L; Aleksunes, Lauren M; Zhu, Hao P30ES005022, R01ES031080, R15ES023148, R15ES023148 Drug Discov Today (2020 09) 32663517 Exiting the NIEHS site 2020 
Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research.   Neuman, Manuela G; Seitz, Helmut Karl; French, Samuel W; Malnick, Stephen; Tsukamoto, Heidekazu ... R15ES023685, R15ES023685 Biomedicines (2020 Mar 18) 32197424 Exiting the NIEHS site 2020 
An aryl hydrocarbon receptor from the caecilian Gymnopis multiplicata suggests low dioxin affinity i ...   Kazzaz, Sarah A; Giani Tagliabue, Sara; Franks, Diana G; Denison, Michael S; Hahn, Mark E; Bona ... R15ES011130, R15ES011130 Gen Comp Endocrinol (2020 12 01) 32858041 Exiting the NIEHS site 2020 
Analysis of model PM2.5-induced inflammation and cytotoxicity by the combination of a virtual carbon ...   Liu, Guohong; Yan, Xiliang; Sedykh, Alexander; Pan, Xiujiao; Zhao, Xiaoli; Yan, Bing; Zhu, Ha ... R15ES023148, R15ES023148 Ecotoxicol Environ Saf (2020 Mar 15) 31972454 Exiting the NIEHS site 2020 
Big Data and Artificial Intelligence Modeling for Drug Discovery.   Zhu, Hao R15ES023148, R15ES023148 Annu Rev Pharmacol Toxicol (2020 01 06) 31518513 Exiting the NIEHS site 2020 
CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskel ...   Salem, Fatema B; Bunner, Wyatt P; Prabhu, Vishwanath V; Kuyateh, Abu-Bakarr; O'Bryant, Collin T ... R15ES029673, R15ES029673, R15ES029673, R15ES029673 J Biol Chem (2020 08 07) 32424038 Exiting the NIEHS site 2020 
Construction of a web-based nanomaterial database by big data curation and modeling friendly nanostr ...   Yan, Xiliang; Sedykh, Alexander; Wang, Wenyi; Yan, Bing; Zhu, Hao P30ES005022, R01ES031080, R15ES023148, R15ES023148 Nat Commun (2020 05 20) 32433469 Exiting the NIEHS site 2020 
Dugesia japonica is the best suited of three planarian species for high-throughput toxicology screen ...   Ireland, Danielle; Bochenek, Veronica; Chaiken, Daniel; Rabeler, Christina; Onoe, Sumi; Soni, ... R15ES031354, R15ES031354 Chemosphere (2020 Aug) 32298908 Exiting the NIEHS site 2020 
Gender differences in diet-induced steatotic disease in Cyp2b-null mice.   Heintz, Melissa M; McRee, Rebecca; Kumar, Ramiya; Baldwin, William S R15ES017321, R15ES017321 PLoS One (2020) 32155178 Exiting the NIEHS site 2020 
Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2 ...   St John, Nick; Freedland, Julian; Baldino, Henri; Doyle, Francis; Cera, Cinzia; Begley, Thomas ... R15ES023685, R15ES023685 G3 (Bethesda) (2020 11 05) 32994210 Exiting the NIEHS site 2020 
Induction of Eryptosis in Red Blood Cells Using a Calcium Ionophore.   Bigdelou, Parnian; Farnoud, Amir M R15ES030140, R15ES030140 J Vis Exp (2020 01 21) 32065143 Exiting the NIEHS site 2020 
Lipid Chemical Structure Modulates the Disruptive Effects of Nanomaterials on Membrane Models.   Nazemidashtarjandi, Saeed; Vahedi, Amid; Farnoud, Amir M R15ES030140, R15ES030140 Langmuir (2020 05 12) 32312045 Exiting the NIEHS site 2020 
Loss of membrane asymmetry alters the interactions of erythrocytes with engineered silica nanopartic ...   Bigdelou, Parnian; Vahedi, Amid; Kiosidou, Evangelia; Farnoud, Amir M R15ES030140, R15ES030140 Biointerphases (2020 06 29) 32600052 Exiting the NIEHS site 2020 
Mechanism-Driven Read-Across of Chemical Hepatotoxicants Based on Chemical Structures and Biological ...   Zhao, Linlin; Russo, Daniel P; Wang, Wenyi; Aleksunes, Lauren M; Zhu, Hao P30ES005022, R01ES031080, R15ES023148, R15ES023148 Toxicol Sci (2020 04 01) 32073637 Exiting the NIEHS site 2020 
Selective Autophagy Maintains the Aryl Hydrocarbon Receptor Levels in HeLa Cells: A Mechanism That I ...   Yang, Yujie; Chan, William K R15ES023104, R15ES023104 Int J Mol Sci (2020 May 13) 32414129 Exiting the NIEHS site 2020 
Supplemental taurine during adolescence and early adulthood has sex-specific effects on cognition, b ...   Brown, Josephine; Villalona, Yislain; Weimer, Jamie; Ludwig, Clare Pickering; Hays, Breann T; M ... R15ES030541, R15ES030541 Neurotoxicol Teratol (2020 May - Jun) 32289445 Exiting the NIEHS site 2020 
Targeting Dysfunctional Vascular Endothelial Cells Using Immunoliposomes Under Flow Conditions.   Kheradmandi, Mahsa; Ackers, Ian; Burdick, Monica M; Malgor, Ramiro; Farnoud, Amir M R15ES030140, R15ES030140 Cell Mol Bioeng (2020 Jun) 32426057 Exiting the NIEHS site 2020 
Advancing Computational Toxicology in the Big Data Era by Artificial Intelligence: Data-Driven and M ...   Ciallella, Heather L; Zhu, Hao R15ES023148, R15ES023148 Chem Res Toxicol (2019 04 15) 30907586 Exiting the NIEHS site 2019 
Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced N ...   Rooney, John P; Oshida, Keiyu; Kumar, Ramiya; Baldwin, William S; Corton, J Christopher R15ES017321, R15ES017321 Toxicol Sci (2019 01 01) 30203046 Exiting the NIEHS site 2019 
Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis.   Heintz, Melissa M; Kumar, Ramiya; Rutledge, Meredith M; Baldwin, William S R15ES017321, R15ES017321 J Nutr Biochem (2019 08) 31202118 Exiting the NIEHS site 2019 
Down-Regulation of p23 in Normal Lung Epithelial Cells Reduces Toxicities From Exposure to Benzo[a]p ...   Chen, Jinyun; Yakkundi, Poonam; Chan, William K R15ES023104, R15ES023104 Toxicol Sci (2019 01 01) 30204910 Exiting the NIEHS site 2019 
Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across.   Russo, Daniel P; Strickland, Judy; Karmaus, Agnes L; Wang, Wenyi; Shende, Sunil; Hartung, Thom ... R15ES023148, R15ES023148 Environ Health Perspect (2019 04) 30933541 Exiting the NIEHS site 2019 
Novel Experimental Modules to Introduce Students to Nanoparticle Characterization in a Chemical Engi ...   Vahedi, Amid; Farnoud, Amir M R15ES030140, R15ES030140 J Chem Educ (2019 Sep 10) 34045773 Exiting the NIEHS site 2019 
Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selec ...   Zhu, Haizhou; Mishra, Rosalin; Yuan, Long; Abdul Salam, Safnas F; Liu, Jing; Gray, George; Ste ... R15ES029675, R15ES029675 ChemMedChem (2019 11 20) 31696673 Exiting the NIEHS site 2019 
Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors as a First Ste ...   Baldwin, William S R15ES017321, R15ES017321 Nucl Receptor Res (2019) 31815118 Exiting the NIEHS site 2019 
Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance.   Liu, Zhenxing; Tabuloc, Christine A; Xue, Yongbo; Cai, Yao; Mcintire, Pearson; Niu, Ye; Lam, ... R15ES030548, R15ES030548 PLoS Genet (2019 10) 31658266 Exiting the NIEHS site 2019 
SUR-8 interacts with PP1-87B to stabilize PERIOD and regulate circadian rhythms in Drosophila.   Xue, Yongbo; Chiu, Joanna C; Zhang, Yong R15ES030548, R15ES030548 PLoS Genet (2019 11) 31710605 Exiting the NIEHS site 2019 
tRNA modification and cancer: potential for therapeutic prevention and intervention.   Endres, Lauren; Fasullo, Michael; Rose, Rebecca R15ES023685, R15ES023685 Future Med Chem (2019 04) 30744422 Exiting the NIEHS site 2019 
Using a hybrid read-across method to evaluate chemical toxicity based on chemical structure and biol ...   Guo, Yajie; Zhao, Linlin; Zhang, Xiaoyi; Zhu, Hao R15ES023148, R15ES023148 Ecotoxicol Environ Saf (2019 Aug 30) 31004930 Exiting the NIEHS site 2019 
Comparing Multiple Machine Learning Algorithms and Metrics for Estrogen Receptor Binding Prediction.   Russo, Daniel P; Zorn, Kimberley M; Clark, Alex M; Zhu, Hao; Ekins, Sean R15ES023148, R15ES023148 Mol Pharm (2018 10 01) 30114914 Exiting the NIEHS site 2018 
Cyp2b-Knockdown Mice Poorly Metabolize Corn Oil and Are Age-Dependent Obese.   Damiri, Basma; Baldwin, William S R15ES017321, R15ES017321 Lipids (2018 09) 30421529 Exiting the NIEHS site 2018 
Dioxin Exposure Alters Molecular and Morphological Responses to Thyroid Hormone in Xenopus laevis Cu ...   Taft, Justin D; Colonnetta, Megan M; Schafer, Rachel E; Plick, Natalie; Powell, Wade H R15ES011130, R15ES011130 Toxicol Sci (2018 01 01) 29294139 Exiting the NIEHS site 2018 
DNA damaging agents trigger the expression of the HML silent mating type locus in Saccharomyces cere ...   Derevensky, Michael; Fasullo, Michael R15ES023685, R15ES023685 Mutat Res Genet Toxicol Environ Mutagen (2018 Nov) 30249477 Exiting the NIEHS site 2018 
High fat diet induced obesity is mitigated in Cyp3a-null female mice.   Kumar, Ramiya; Litoff, Elizabeth J; Boswell, W Tyler; Baldwin, William S R15ES017321, R15ES017321 Chem Biol Interact (2018 Jun 01) 29738703 Exiting the NIEHS site 2018 
Non-Mammalian Nuclear Receptors: From Evolution to Human Disease.   Gissendanner, Chris R; Baldwin, William S; Schaaf, Marcel J M R15ES017321, R15ES017321 Nucl Receptor Res (2018) 30221173 Exiting the NIEHS site 2018 
p23 protects the human aryl hydrocarbon receptor from degradation via a heat shock protein 90-indepe ...   Pappas, Beverly; Yang, Yujie; Wang, Yu; Kim, Kyung; Chung, Hee Jae; Cheung, Michael; Ngo, Kat ... R15ES023104, R15ES023104 Biochem Pharmacol (2018 06) 29555469 Exiting the NIEHS site 2018 
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory t ...   Hamm, Jon; Sullivan, Kristie; Clippinger, Amy J; Strickland, Judy; Bell, Shannon; Bhhatarai, B ... P30ES005022, R15ES023148, R15ES023148 Toxicol In Vitro (2017 Jun) 28069485 Exiting the NIEHS site 2017 
An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae.   Fasullo, Michael; Freedland, Julian; St John, Nicholas; Cera, Cinzia; Egner, Patricia; Hartog, ... R15ES023685, R15ES023685 Environ Mol Mutagen (2017 05) 28436563 Exiting the NIEHS site 2017 
Annotation of the Nuclear Receptors in an Estuarine Fish species, Fundulus heteroclitus.   Baldwin, William S; Boswell, W Tyler; Ginjupalli, Gautam; Litoff, Elizabeth J R15ES017321, R15ES017321 Nucl Receptor Res (2017) 28804711 Exiting the NIEHS site 2017 
Both RAD5-dependent and independent pathways are involved in DNA damage-associated sister chromatid ...   Fasullo, Michael T; Sun, Mingzeng R15ES023685, R15ES023685 AIMS Genet (2017) 28596989 Exiting the NIEHS site 2017 
CIIPro: a new read-across portal to fill data gaps using public large-scale chemical and biological ...   Russo, Daniel P; Kim, Marlene T; Wang, Wenyi; Pinolini, Daniel; Shende, Sunil; Strickland, Jud ... P30ES005022, R15ES023148, R15ES023148 Bioinformatics (2017 02 01) 28172359 Exiting the NIEHS site 2017 
Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-n ...   Kumar, Ramiya; Mota, Linda C; Litoff, Elizabeth J; Rooney, John P; Boswell, W Tyler; Courter, ... R15ES017321, R15ES017321 PLoS One (2017) 28350814 Exiting the NIEHS site 2017 
CYP1A1 I462V polymorphism is associated with reduced genotoxicity in yeast despite positive associat ...   Freedland, Julian; Cera, Cinzia; Fasullo, Michael R15ES023685, R15ES023685 Mutat Res Genet Toxicol Environ Mutagen (2017 Mar) 28283091 Exiting the NIEHS site 2017 
Elucidation of the Molecular Determinants for Optimal Perfluorooctanesulfonate Adsorption Using a Co ...   Liu, Yin; Su, Gaoxing; Wang, Fei; Jia, Jianbo; Li, Shuhuan; Zhao, Linlin; Shi, Yali; Cai, Ya ... R15ES023148, R15ES023148 Environ Sci Technol (2017 Jun 20) 28537376 Exiting the NIEHS site 2017 
Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin al ...   Sengupta, Namrata; Reardon, Delaney C; Gerard, Patrick D; Baldwin, William S R15ES017321, R15ES017321 PLoS One (2017) 28542405 Exiting the NIEHS site 2017 
Experimental Errors in QSAR Modeling Sets: What We Can Do and What We Cannot Do.   Zhao, Linlin; Wang, Wenyi; Sedykh, Alexander; Zhu, Hao P30ES005022, R15ES023148, R15ES023148 ACS Omega (2017 Jun 30) 28691113 Exiting the NIEHS site 2017 
Predicting Nano-Bio Interactions by Integrating Nanoparticle Libraries and Quantitative Nanostructur ...   Wang, Wenyi; Sedykh, Alexander; Sun, Hainan; Zhao, Linlin; Russo, Daniel P; Zhou, Hongyu; Yan, ... P30ES005022, R15ES023148, R15ES023148 ACS Nano (2017 12 26) 29149552 Exiting the NIEHS site 2017 
RNA sequencing indicates that atrazine induces multiple detoxification genes in Daphnia magna and th ...   Schmidt, Allison M; Sengupta, Namrata; Saski, Christopher A; Noorai, Rooksana E; Baldwin, Willi ... R15ES017321, R15ES017321 Chemosphere (2017 Dec) 28968576 Exiting the NIEHS site 2017 
Subfunctionalization of Paralogous Aryl Hydrocarbon Receptors from the Frog Xenopus Laevis: Distinct ...   Freeburg, Scott H; Engelbrecht, Eric; Powell, Wade H R15ES011130, R15ES011130 Toxicol Sci (2017 02) 27994169 Exiting the NIEHS site 2017 
Toward a systematic exploration of nano-bio interactions.   Bai, Xue; Liu, Fang; Liu, Yin; Li, Cong; Wang, Shenqing; Zhou, Hongyu; Wang, Wenyi; Zhu, Hao ... P30ES005022, R15ES023148, R15ES023148 Toxicol Appl Pharmacol (2017 05 15) 28344110 Exiting the NIEHS site 2017 
Accessing the High-Throughput Screening Data Landscape.   Russo, Daniel P; Zhu, Hao R15ES023148, R15ES023148 Methods Mol Biol (2016) 27518633 Exiting the NIEHS site 2016 
Analysis of Draize eye irritation testing and its prediction by mining publicly available 2008-2014 ...   Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... R15ES023148, R15ES023148, T32ES007141 ALTEX (2016) 26863293 Exiting the NIEHS site 2016 
Analysis of public oral toxicity data from REACH registrations 2008-2014.   Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... R15ES023148, R15ES023148, T32ES007141 ALTEX (2016) 26863198 Exiting the NIEHS site 2016 
Analysis of publically available skin sensitization data from REACH registrations 2008-2014.   Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... R15ES023148, R15ES023148, T32ES007141 ALTEX (2016) 26863411 Exiting the NIEHS site 2016 
Binding studies using Pichia pastoris expressed human aryl hydrocarbon receptor and aryl hydrocarbon ...   Zheng, Yujuan; Xie, Jinghang; Huang, Xin; Dong, Jin; Park, Miki S; Chan, William K R15ES023104, R15ES023104 Protein Expr Purif (2016 06) 26923060 Exiting the NIEHS site 2016 
CIIPro: a new read-across portal to fill data gaps using public large-scale chemical and biological ...   Russo, Daniel P; Kim, Marlene T; Wang, Wenyi; Pinolini, Daniel; Shende, Sunil; Strickland, Jud ... P30ES005022, R15ES023148, R15ES023148 Bioinformatics (2016 Oct 14) 27742693 Exiting the NIEHS site 2016 
Curating and Preparing High-Throughput Screening Data for Quantitative Structure-Activity Relationsh ...   Kim, Marlene T; Wang, Wenyi; Sedykh, Alexander; Zhu, Hao R15ES023148, R15ES023148 Methods Mol Biol (2016) 27518634 Exiting the NIEHS site 2016 
Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combinin ...   Xiang, Jinbao; Zhang, Zhuoqi; Mu, Yan; Xu, Xianxiu; Guo, Sigen; Liu, Yongjin; Russo, Daniel P ... P30ES005022, R15ES023148, R15ES023148 ACS Comb Sci (2016 05 09) 27082930 Exiting the NIEHS site 2016 
From fighting depression to conquering tumors: a novel tricyclic thiazepine compound as a tubulin po ...   Mu, Y; Liu, Y; Xiang, J; Zhang, Q; Zhai, S; Russo, D P; Zhu, H; Bai, X; Yan, B R15ES023148, R15ES023148 Cell Death Dis (2016 Mar 17) 26986511 Exiting the NIEHS site 2016 
Global analysis of publicly available safety data for 9,801 substances registered under REACH from 2 ...   Luechtefeld, Thomas; Maertens, Alexandra; Russo, Daniel P; Rovida, Costanza; Zhu, Hao; Hartung, ... R15ES023148, R15ES023148, T32ES007141 ALTEX (2016) 26863090 Exiting the NIEHS site 2016 
Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element ...   Kim, Marlene Thai; Huang, Ruili; Sedykh, Alexander; Wang, Wenyi; Xia, Menghang; Zhu, Hao P30ES005022, R15ES023148, R15ES023148 Environ Health Perspect (2016 05) 26383846 Exiting the NIEHS site 2016 
Perturbations in polar lipids, starvation survival and reproduction following exposure to unsaturate ...   Sengupta, Namrata; Gerard, Patrick D; Baldwin, William S R15ES017321, R15ES017321 Chemosphere (2016 Feb) 26606184 Exiting the NIEHS site 2016 
Predictive Modeling of Estrogen Receptor Binding Agents Using Advanced Cheminformatics Tools and Mas ...   Ribay, Kathryn; Kim, Marlene T; Wang, Wenyi; Pinolini, Daniel; Zhu, Hao P30ES005022, R15ES023148, R15ES023148 Front Environ Sci (2016 Mar) 27642585 Exiting the NIEHS site 2016 
Selective suppression of the human aryl hydrocarbon receptor function can be mediated through bindin ...   Ren, Lina; Thompson, John D; Cheung, Michael; Ngo, Katherine; Sung, Sarah; Leong, Scott; Chan, ... R15ES023104, R15ES023104 Biochem Pharmacol (2016 May 01) 26970402 Exiting the NIEHS site 2016 
Supporting read-across using biological data.   Zhu, Hao; Bouhifd, Mounir; Donley, Elizabeth; Egnash, Laura; Kleinstreuer, Nicole; Kroese, E D ... P30ES005022, R15ES023148, R15ES023148, T32ES007141 ALTEX (2016) 26863516 Exiting the NIEHS site 2016 
Toward Good Read-Across Practice (GRAP) guidance.   Ball, Nicholas; Cronin, Mark T D; Shen, Jie; Blackburn, Karen; Booth, Ewan D; Bouhifd, Mounir; ... P30ES005022, R15ES023148, R15ES023148, T32ES007141 ALTEX (2016) 26863606 Exiting the NIEHS site 2016 
An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3 ...   Shoots, Jenny; Fraccalvieri, Domenico; Franks, Diana G; Denison, Michael S; Hahn, Mark E; Bonat ... R15ES011130, R15ES011130 Environ Sci Technol (2015 Jun 02) 25941739 Exiting the NIEHS site 2015 
Arachidonic acid enhances reproduction in Daphnia magna and mitigates changes in sex ratios induced ...   Ginjupalli, Gautam K; Gerard, Patrick D; Baldwin, William S R15ES017321, R15ES017321 Environ Toxicol Chem (2015 Mar) 25393616 Exiting the NIEHS site 2015 
Developing Enhanced Blood-Brain Barrier Permeability Models: Integrating External Bio-Assay Data in ...   Wang, Wenyi; Kim, Marlene T; Sedykh, Alexander; Zhu, Hao R15ES023148, R15ES023148 Pharm Res (2015 Sep) 25862462 Exiting the NIEHS site 2015 
Experimental modulation and computational model of nano-hydrophobicity.   Li, Shuhuan; Zhai, Shumei; Liu, Yin; Zhou, Hongyu; Wu, Jinmei; Jiao, Qing; Zhang, Bin; Zhu, ... R15ES023148, R15ES023148 Biomaterials (2015 Jun) 25818437 Exiting the NIEHS site 2015 
Improving both aqueous solubility and anti-cancer activity by assessing progressive lead optimizatio ...   Liu, Yin; Li, Fei; Wu, Ling; Wang, Wenyi; Zhu, Hao; Zhang, Qiu; Zhou, Hongyu; Yan, Bing R15ES023148, R15ES023148 Bioorg Med Chem Lett (2015 May 01) 25827524 Exiting the NIEHS site 2015 
Repression of multiple CYP2D genes in mouse primary hepatocytes with a single siRNA construct.   Elraghy, Omaima; Baldwin, William S R15ES017321, R15ES017321 In Vitro Cell Dev Biol Anim (2015 Jan) 25124873 Exiting the NIEHS site 2015 
The HR96 activator, atrazine, reduces sensitivity of D. magna to triclosan and DHA.   Sengupta, Namrata; Litoff, Elizabeth J; Baldwin, William S R15ES017321, R15ES017321 Chemosphere (2015 Jun) 25747156 Exiting the NIEHS site 2015 
Activation of aflatoxin B1 by expression of human CYP1A2 polymorphisms in Saccharomyces cerevisiae.   Fasullo, Michael; Smith, Autumn; Egner, Patricia; Cera, Cinzia R15ES023685, R15ES023685 Mutat Res Genet Toxicol Environ Mutagen (2014 Feb) 24472830 Exiting the NIEHS site 2014 
Annotation of the Daphnia magna nuclear receptors: comparison to Daphnia pulex.   Litoff, Elizabeth J; Garriott, Travis E; Ginjupalli, Gautam K; Butler, LaToya; Gay, Claudy; Sco ... R15ES017321, R15ES017321 Gene (2014 Nov 15) 25239664 Exiting the NIEHS site 2014 
Big data in chemical toxicity research: the use of high-throughput screening assays to identify pote ...   Zhu, Hao; Zhang, Jun; Kim, Marlene T; Boison, Abena; Sedykh, Alexander; Moran, Kimberlee R15ES023148, R15ES023148 Chem Res Toxicol (2014 Oct 20) 25195622 Exiting the NIEHS site 2014 
Bisphenol A regulation of testicular endocrine function in male rats is affected by diet.   Nanjappa, Manjunatha K; Ahuja, Manuj; Dhanasekaran, Muralikrishnan; Coleman, Elaine S; Braden, ... R15ES015886, R15ES015886, R15ES015886, R15ES015886 Toxicol Lett (2014 Mar 21) 24472609 Exiting the NIEHS site 2014 
Critical evaluation of human oral bioavailability for pharmaceutical drugs by using various cheminfo ...   Kim, Marlene T; Sedykh, Alexander; Chakravarti, Suman K; Saiakhov, Roustem D; Zhu, Hao R15ES023148, R15ES023148 Pharm Res (2014 Apr) 24306326 Exiting the NIEHS site 2014 
Design, synthesis and experimental validation of novel potential chemopreventive agents using random ...   Sprague, Brienne; Shi, Qian; Kim, Marlene T; Zhang, Liying; Sedykh, Alexander; Ichiishi, Eiich ... R15ES023148, R15ES023148 J Comput Aided Mol Des (2014 Jun) 24840854 Exiting the NIEHS site 2014 
Profiling animal toxicants by automatically mining public bioassay data: a big data approach for com ...   Zhang, Jun; Hsieh, Jui-Hua; Zhu, Hao R15ES023148, R15ES023148 PLoS One (2014) 24950175 Exiting the NIEHS site 2014 
Testicular development in male rats is sensitive to a soy-based diet in the neonatal period.   Napier, India D; Simon, Liz; Perry, Devin; Cooke, Paul S; Stocco, Douglas M; Sepehr, Estatira; ... R15ES015886, R15ES015886, R15ES015886, R15ES015886 Biol Reprod (2014 Feb) 24451983 Exiting the NIEHS site 2014 
The HR97 (NR1L) group of nuclear receptors: a new group of nuclear receptors discovered in Daphnia s ...   Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S R15ES017321, R15ES017321 Gen Comp Endocrinol (2014 Sep 15) 25092536 Exiting the NIEHS site 2014 
Tuning cell autophagy by diversifying carbon nanotube surface chemistry.   Wu, Ling; Zhang, Yi; Zhang, Chengke; Cui, Xuehui; Zhai, Shumei; Liu, Yin; Li, Changlong; Zhu, ... R15ES023148, R15ES023148 ACS Nano (2014 Mar 25) 24552177 Exiting the NIEHS site 2014 
Discovery of novel antimalarial compounds enabled by QSAR-based virtual screening.   Zhang, Liying; Fourches, Denis; Sedykh, Alexander; Zhu, Hao; Golbraikh, Alexander; Ekins, Sean ... R15ES023148, R15ES023148 J Chem Inf Model (2013 Feb 25) 23252936 Exiting the NIEHS site 2013 
From QSAR to QSIIR: searching for enhanced computational toxicology models.   Zhu, Hao R15ES023148, R15ES023148 Methods Mol Biol (2013) 23086837 Exiting the NIEHS site 2013 
Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux an ...   Sedykh, Alexander; Fourches, Denis; Duan, Jianmin; Hucke, Oliver; Garneau, Michel; Zhu, Hao; B ... R15ES023148, R15ES023148 Pharm Res (2013 Apr) 23269503 Exiting the NIEHS site 2013 
Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and ...   Zhang, Liying; Sedykh, Alexander; Tripathi, Ashutosh; Zhu, Hao; Afantitis, Antreas; Mouchlis, ... R15ES023148, R15ES023148 Toxicol Appl Pharmacol (2013 Oct 01) 23707773 Exiting the NIEHS site 2013 
Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis.   Odio, Camila; Holzman, Sarah A; Denison, Michael S; Fraccalvieri, Domenico; Bonati, Laura; Fran ... R15ES011130, R15ES011130 Biochemistry (2013 Mar 12) 23394719 Exiting the NIEHS site 2013 
The time- and age-dependent effects of the juvenile hormone analog pesticide, pyriproxyfen on Daphni ...   Ginjupalli, Gautam K; Baldwin, William S R15ES017321, R15ES017321 Chemosphere (2013 Aug) 23714148 Exiting the NIEHS site 2013 
The use of pseudo-equilibrium constant affords improved QSAR models of human plasma protein binding.   Zhu, Xiang-Wei; Sedykh, Alexander; Zhu, Hao; Liu, Shu-Shen; Tropsha, Alexander R15ES023148, R15ES023148 Pharm Res (2013 Jul) 23568522 Exiting the NIEHS site 2013 
Daphnia HR96 is a promiscuous xenobiotic and endobiotic nuclear receptor.   Karimullina, Elina; Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S R15ES017321, R15ES017321 Aquat Toxicol (2012 Jul 15) 22466357 Exiting the NIEHS site 2012 
Induction of cytochrome P450 family 1 mRNAs and activities in a cell line from the frog Xenopus laev ...   Iwamoto, Daniel V; Kurylo, Chad M; Schorling, Kelly M; Powell, Wade H R15ES011130, R15ES011130 Aquat Toxicol (2012 Jun 15) 22446828 Exiting the NIEHS site 2012 
Lentiviral-mediated RNAi knockdown yields a novel mouse model for studying Cyp2b function.   Damiri, Basma; Holle, Eric; Yu, Xianzhong; Baldwin, William S R15ES017321, R15ES017321 Toxicol Sci (2012 Feb) 22083726 Exiting the NIEHS site 2012 
Predicting chemical ocular toxicity using a combinatorial QSAR approach.   Solimeo, Renee; Zhang, Jun; Kim, Marlene; Sedykh, Alexander; Zhu, Hao R15ES023148, R15ES023148 Chem Res Toxicol (2012 Dec 17) 23148656 Exiting the NIEHS site 2012 
The industrial chemical bisphenol A (BPA) interferes with proliferative activity and development of ...   Nanjappa, Manjunatha K; Simon, Liz; Akingbemi, Benson T R15ES015886, R15ES015886, R15ES015886, R15ES015886 Biol Reprod (2012 May) 22302688 Exiting the NIEHS site 2012 
Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes ...   Mota, Linda C; Barfield, Christina; Hernandez, Juan P; Baldwin, William S R15ES017321, R15ES017321 Toxicol Appl Pharmacol (2011 May 1) 21376070 Exiting the NIEHS site 2011 
Selective imaging and killing of cancer cells with protein-activated near-infrared fluorescing nanop ...   Rungta, Parul; Bandera, Yuriy P; Roeder, Ryan D; Li, Yangchun; Baldwin, William S; Sharma, Dee ... R15ES017321, R15ES017321 Macromol Biosci (2011 Jul 07) 21480531 Exiting the NIEHS site 2011 
Constitutive androstane receptor -null mice are sensitive to the toxic effects of parathion: associa ...   Mota, Linda C; Hernandez, Juan P; Baldwin, William S R15ES017321, R15ES017321 Drug Metab Dispos (2010 Sep) 20573718 Exiting the NIEHS site 2010 
Developmental exposures of male rats to soy isoflavones impact Leydig cell differentiation.   Sherrill, Jessica D; Sparks, Morgan; Dennis, John; Mansour, Mahmoud; Kemppainen, Barbara W; Bar ... R15ES015886, R15ES015886, R15ES015886, R15ES015886 Biol Reprod (2010 Sep) 20554919 Exiting the NIEHS site 2010 
Dose-responsive gene expression changes in juvenile and adult mummichogs (Fundulus heteroclitus) aft ...   Gonzalez, Horacio O; Hu, Jianjun; Gaworecki, Kristen M; Roling, Jonathan A; Baldwin, William S; ... R15ES017321, R15ES017321 Mar Environ Res (2010 Aug) 20451245 Exiting the NIEHS site 2010 
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: ...   Van Aggelen, Graham; Ankley, Gerald T; Baldwin, William S; Bearden, Daniel W; Benson, William H ... R15ES017321, R15ES017321 Environ Health Perspect (2010 Jan) 20056575 Exiting the NIEHS site 2010 
Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription ...   Hannas, Bethany R; Wang, Ying H; Baldwin, William S; Li, Yangchun; Wallace, Andrew D; LeBlanc, ... R15ES017321, R15ES017321, T32ES007046 Gen Comp Endocrinol (2010 Jun 1) 20346363 Exiting the NIEHS site 2010 
Responsiveness of a Xenopus laevis cell line to the aryl hydrocarbon receptor ligands 6-formylindolo ...   Laub, Leo B; Jones, Brian D; Powell, Wade H R15ES011130, R15ES011130 Chem Biol Interact (2010 Jan 05) 19799885 Exiting the NIEHS site 2010 
A concentration addition model for the activation of the constitutive androstane receptor by xenobio ...   Baldwin, William S; Roling, Jonathan A R15ES017321, R15ES017321 Toxicol Sci (2009 Jan) 18832183 Exiting the NIEHS site 2009 
Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolis ...   Hernandez, J P; Mota, L C; Baldwin, W S R15ES017321, R15ES017321 Curr Pharmacogenomics Person Med (2009 Jun 01) 20871735 Exiting the NIEHS site 2009 
Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).   Hernandez, J P; Mota, L C; Huang, W; Moore, D D; Baldwin, W S R15ES017321, R15ES017321 Toxicology (2009 Feb 4) 19041682 Exiting the NIEHS site 2009 
An aryl hydrocarbon receptor repressor from Xenopus laevis: function, expression, and role in dioxin ...   Zimmermann, Anna L; King, Elizabeth A; Dengler, Emelyne; Scogin, Shana R; Powell, Wade H R15ES011130, R15ES011130 Toxicol Sci (2008 Jul) 18385208 Exiting the NIEHS site 2008 
Developmental differences in elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during Xenopu ...   Philips, Blythe H; Susman, Thomas C; Powell, Wade H R15ES011130, R15ES011130 Mar Environ Res (2006 Jul) 16697456 Exiting the NIEHS site 2006 
Aryl hydrocarbon receptors in the frog Xenopus laevis: two AhR1 paralogs exhibit low affinity for 2, ...   Lavine, Jeremy A; Rowatt, Ashley J; Klimova, Tatyana; Whitington, Aric J; Dengler, Emelyne; Bec ... R15ES011130, R15ES011130 Toxicol Sci (2005 Nov) 15958654 Exiting the NIEHS site 2005 
ARNT gene multiplicity in amphibians: characterization of ARNT2 from the frog Xenopus laevis.   Rowatt, Ashley J; DePowell, John J; Powell, Wade H R15ES011130, R15ES011130 J Exp Zool B Mol Dev Evol (2003 Dec 15) 14984034 Exiting the NIEHS site 2003 
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