Superfund Research Program
Spores for the Stabilization and On-Site Application of Bacterial Whole-Cell Biosensing Systems
Patent Status: Expired
Authors: Daunert, S., P. Pasini, S.K. Deo, A. Date
The presently-disclosed subject matter is directed to biosensors comprising spore-forming bacterial cells and/or spores generated therefrom, a recognition unit within each spore-forming cell for binding an analyte of interest, and a reporter molecule within each spore-forming cell for detecting binding of the analyte of interest, wherein the reporter molecule generates a detectable signal upon binding of the analyte by the recognition element. The presently-disclosed subject matter further provides methods of using the biosensors and systems and kits including the biosensors.
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