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Progress Reports: University of California-Berkeley: Research Translation Core

Superfund Research Program

Research Translation Core

Project Leader: Martyn T. Smith
Co-Investigator: Lisa Alvarez-Cohen
Grant Number: P42ES004705
Funding Period: 2006-2022
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Progress Reports

Year:   2020  2019  2018  2017  2016  2014  2013  2011  2010  2009  2008  2007  2006 

The University of California-Berkeley (UC Berkeley) SRP Research Translation Core worked with investigators and trainees to translate and improve the relevance of the team’s research, through partnerships with collaborators including government agencies and others, facilitation of technology transfer, engagement with business and industry, and communication to a broad audience using a variety of tools. The researchers continued to expand the Key Characteristics (KCs) approach, and published papers on male (Arzuaga et al., 2019, PMC6792367) and female (Luderer et al., 2019, PMC6791466) reproductive toxicants and endocrine disruptors (La Merrill et al., 2019, PMC6902641). The research team refined the application of KCs to carcinogenic hazard identification, and the resulting paper is undergoing review. Martyn Smith and Lauren Zeise (OEHHA) hosted a meeting, Key Characteristics of Neurotoxicants, at the University of California-Davis in September 2019. An expert working group with participants from academia, U.S. EPA, U.S. FDA, and NIEHS identified KCs of neurotoxicants that could be used to support hazard identification and are drafting a manuscript. The researchers hosted a large interactive workshop, The Problem of PFAS Contamination in California: How Can We Make Rapid Progress to Address it?, in Berkeley on December 13, 2019. The focus was on applying grouping and read-across approaches. The investigators have actively engaged in research translation efforts in a variety of ways during this research period including assessment of Superfund chemicals, and developing and promoting approaches and research strategies to improve toxicity testing and hazard assessment. The researchers have been proactive in sharing these efforts through NIEHS and their own web and social media outlets.

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