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Your Environment. Your Health.

Progress Reports: Boston University: Early Life Exposure to Tetrachloroethylene (PCE)-Contaminated Drinking Water and Social Stressors may Interact to Increase the Risk of Substance Use Later in Life

Superfund Research Program

Early Life Exposure to Tetrachloroethylene (PCE)-Contaminated Drinking Water and Social Stressors may Interact to Increase the Risk of Substance Use Later in Life

Project Leader: Ann Aschengrau
Co-Investigators: Lisa Gallagher, Richard Saitz, Renee Boynton-Jarrett
Grant Number: P42ES007381
Funding Period: 2000-2020
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Progress Reports

Year:   2019  2018  2017  2016  2015  2014  2013  2012  2010  2009  2008  2007  2006  2005  2004  2003  2002  2001  2000 

Over the past year, Aschengrau and her team have finalized the study questionnaire after cognitive and pre-testing; identified approximately 200 birth defect cases and 200 controls; nearly completed gathering and incorporating the exposure data into a Geographic Information System; and communicated goals of the BU SRP and this project to local and state authorities, including water companies, engineering departments, librarians, and historical societies, and the Massachusetts Department of Environmental Protection. Aschengrau and her team have also prepared two manuscripts describing the impact of early life exposure to PCE on the occurrence of placental dysfunction disorders and the risk of cancer and other adverse health outcomes; collaborated with the Analyzing Patterns in Epidemiologic and Toxicologic Data project on a manuscript describing spatial analyses of mental illness; and collaborated with investigators at Harvard University on manuscripts on the risk of benign gynecological conditions in relation to air pollution. Aschengrau also presented her PCE exposure assessment methods and research findings at the annual meeting of the International Society of Exposure Science, and chaired a session on drinking water contaminants at the annual meeting of the International Society for Environmental Epidemiology.

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