Superfund Research Program
Early Life Exposure to Tetrachloroethylene (PCE)-Contaminated Drinking Water and Social Stressors may Interact to Increase the Risk of Substance Use Later in Life
Over the past year, Aschengrau and her team have finalized the study questionnaire after cognitive and pre-testing; identified approximately 200 birth defect cases and 200 controls; nearly completed gathering and incorporating the exposure data into a Geographic Information System; and communicated goals of the BU SRP and this project to local and state authorities, including water companies, engineering departments, librarians, and historical societies, and the Massachusetts Department of Environmental Protection. Aschengrau and her team have also prepared two manuscripts describing the impact of early life exposure to PCE on the occurrence of placental dysfunction disorders and the risk of cancer and other adverse health outcomes; collaborated with the Analyzing Patterns in Epidemiologic and Toxicologic Data project on a manuscript describing spatial analyses of mental illness; and collaborated with investigators at Harvard University on manuscripts on the risk of benign gynecological conditions in relation to air pollution. Aschengrau also presented her PCE exposure assessment methods and research findings at the annual meeting of the International Society of Exposure Science, and chaired a session on drinking water contaminants at the annual meeting of the International Society for Environmental Epidemiology.