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Your Environment. Your Health.

Person Details: Dean E. Carter

Superfund Research Program

Dean E. Carter

University of Arizona
College of Pharmacy
PO Box 210207
Tuscon, Arizona 85721-0207
Phone: 520-626-4294
Fax: 520-626-2466




  • Peraza MA, Cromey DW, Carolus B, Carter DE, Gandolfi A. 2006. Morphological and functional alterations in human proximal tubular cell line induced by low level inorganic arsenic: evidence for targeting of mitochondria and initiated apoptosis. J Appl Toxicol 26(4):356-67. PMID:16773642


  • Aposhian HV, Zakharyan RA, Healy SM, Wildfang E, Petrick JS, Sampayo-Reyes A, Board PG, Carter DE, Mazumder G, Aposhian MM. 2003. Enzymology and Toxicity of Inorganic Arsenic. In: Arsenic Exposure and Health Effects: Proceedings of the Fifth International Conference on Arsenic Exposure and Health Effects, San Diego, California. Elsiever Science Ltd., Oxford, United Kingdom. pp.225-240.
  • Carter DE, Aposhian HV, Gandolfi A. 2003. The metabolism of inorganic arsenic oxides, gallium arsenide, and arsine: a toxicochemical review. Toxicol Appl Pharmacol 193(3):309-334. PMID:14678742
  • Peraza MA, Carter DE, Gandolfi A. 2003. Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2). Cell Biol Toxicol 19(4):253-264. PMID:14686617


  • Peraza MA, Kopplin MJ, Carter DE, Gandolfi A. 2002. Inorganic arsenic biotransformation and mitochondrial toxicity in HK-2 human proximal tubular cells. Environ Health Perspect 66:A403.


  • Ayala-Fierro F, Baldwin AL, Wilson LM, Valeski JE, Carter DE. 2000. Structural alterations in the rat kidney after acute arsine exposure. Laboratory Investigation 80(1):87-97. PMID:10653007
  • Ayala-Fierro F, Carter DE. 2000. LLC-PK1 cells as a model for renal toxicity caused by arsine exposure. J Toxicol Environ Health A 60:67-79. PMID:10832618
  • Mitchell RD, Ayala-Fierro F, Carter DE. 2000. Systemic indicators of inorganic arsenic toxicity in four animal species. J Toxicol Environ Health A 59(2):119-134. doi:10.1080/009841000157014 PMID:10653439
  • Petrick JS, Ayala-Fierro F, Cullen WR, Carter DE, Aposhian HV. 2000. Monomethylarsonous acid (MMAIII) is more toxic than arsenite in chang human hepatocytes. Toxicol Appl Pharmacol 163(2):203-207. PMID:10698679
  • Petrick JS, Ayala-Fierro F, Cullen WR, Carter DE, Aposhian HV. 2000. The most toxic arsenical in the inorganic arsenic biotransformation pathway. In: Proceedings of the Fourth International Conference on Arsenic Exposure and Health Effects. San Diego, CA.
  • Rael LT, Ayala-Fierro F, Carter DE. 2000. The effects of sulfur-, thiol-, and thiol inhibitor compounds on arsine-induced toxicity in the human erythrocyte membrane. Toxicol Sci 55(2):468-477. PMID:10828280
  • Varady RG, Arnold RG, Carter DE, Guzman R, Pena C. 2000. Hazardous waste and the U.S.-Mexico border region. Toward a binational, university-based institution. Environmental Practice 2(1):38-45.


  • Ayala-Fierro F, Barber DS, Rael LT, Carter DE. 1999. In vitro tissue specificity for arsine and arsenite toxicity in the rat. Toxicol Sci 52(1):122-129. PMID:10568705
  • Divine KK, Ayala-Fierro F, Barber DS, Carter DE. 1999. Glutathione, albumin, cysteine, and cys-gly effects on toxicity and accumulation of mercury chloride in porcine renal proximal tubular epithelial cells. J Toxicol Environ Health A 57(7):489-505.
  • Zakharyan RA, Ayala-Fierro F, Cullen WR, Carter DE, Aposhian HV. 1999. Enzymatic methylation of arsenic compounds: VII. Monomethylarsonous acid (MMAIII) is the substrate for MMA methyltransferase of rabbit liver and human hepatocytes. Toxicol Appl Pharmacol 158(1):9-15. PMID:10387927


  • Winski SL, Carter DE. 1998. Arsenate toxicity in human erythrocytes: characterization of morphologic changes and determination of the mechanism of damage. J Toxicol Environ Health A 53(A):345-355. PMID:9515938


  • Barber DS, Ayala-Fierro F, Casarez EA, Rael LT, Winski SL, Carter DE. 1997. Introduction to Environmental Toxicology. In: Environment and Health. UNAM, Programa Universitario de Medio Ambiente, Mexico City, Mexico.
  • Carter DE, Pena C. 1997. Superfund Basic Research Program Mexico Outreach Core. Center for Toxicology Newsletter


  • Carter DE, Pena C, Varady RG, Suk WA. 1996. Environmental health and hazardous waste issues related to the U.S. Mexico border. Environ Health Perspect 104(6):590-594. PMID:8793340


  • Burton CA, Hatlelid K, Divine KK, Carter DE, Fernando Q, Brendel K, Gandolfi A. 1995. Glutathione effects on toxicity and uptake of mercuric chloride and sodium arsenite in rabbit renal cortical slices. Environ Health Perspect 103(Suppl.1):81-84. PMID:7621807
  • Winski SL, Carter DE. 1995. Interactions of rat red blood cell sulfhydryls with arsenate and arsenite. J Toxicol Environ Health A 46(3):379-397. PMID:7473865
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