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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Person Details: Dr. Barbara J. Strupp

Superfund Research Program

Dr. Barbara J. Strupp

Cornell University
109 Savage Hall

Ithaca, New York 14853-6301
Phone: 607-255-2694
Fax: 607-255-1033
Email: bjs13@cornell.edu

Projects

Research Briefs

Publications

2004

  • Driscoll LL, Carroll JC, Moon J, Crnic LS, Levitsky DA, Strupp BJ. 2004. Imparied sustained attention and error-induced stereotypy in the aged Ts65Dn mouse: a mouse model of Down syndrome and Alzheimer's disease. Behav Neurosci 118(6):1196-1205. PMID:15598129
  • Stangle DE, Strawderman MS, Smith D, Kuypers M, Strupp BJ. 2004. Reductions in blood lead overestimate reductions in brain lead following repeated succimer regimens in a rodent model of chilhood lead exposure. Environ Health Perspect 112(3):302-308.

2001

  • Morgan RE, Garavan H, Smith EG, Driscoll LL, Levitsky DA, Strupp BJ. 2001. Early lead exposure produces lasting changes in sustained attention, response initiation, and reactivity to errors. Neurotoxicol Teratol 23(6):519-531. PMID:11792522

2000

  • Bayer LE, Brown AP, Mactutus CF, Booze RM, Strupp BJ. 2000. Prenatal cocaine exposure increases sensitivity to the attentional effects of the dopamine D1 agonist SKF81297. J Neurosci 20(23):8902-8908. PMID:11102500
  • Beaudin S, White TL, Hermer-Vasquez L, Strangle D, Strupp BJ. 2000. Enduring attentional dysfunction following a short period of early postnatal lead exposure: Evidence for an inverted U-shaped dose-response curve. Neurotoxicol Teratol 22:459.
  • Bushnell PJ, Marrocco RT, Strupp BJ, Sarter MF, Levin ED, Warburton DH. 2000. Attention as a target of intoxication; Insights and methods from studies of drug abuse. Neurotoxicol Teratol 22(4):487-502. PMID:10974587
  • Garavan H, Morgan RE, Levitsky DA, Hermer-Vasquez L, Strupp BJ. 2000. Enduring effects of early lead exposure: Evidence for a specific deficit in associative ability. Neurotoxicol Teratol 22(2):151-164. PMID:10758344
  • Garavan H, Morgan RE, Mactutus CF, Levitsky DA, Booze RM, Strupp BJ. 2000. Prenatal cocaine exposure impairs selective attention: evidence from serial reversal and extradimensional shift tasks. Behav Neurosci 114(4):725-738. PMID:10959532
  • Morgan RE, Levitsky DA, Strupp BJ. 2000. Effects of chronic lead exposure on learning and reaction time in a visual discrimination task. Neurotoxicol Teratol 22(3):337-345. PMID:10840177
  • Strangle D, Beaudin S, White TL, Hermer-Vasquez L, Strupp BJ. 2000. The effects of early postnatal lead exposure on selective attention. Neurotoxicol Teratol 22:456.
  • Strupp BJ, Driscoll LL, Beaudin S, Hermer-Vasquez L, Garavan H, Levitsky DA. 2000. Early lead (Pb) exposure: the emerging cognitive profile. Neurotoxicol Teratol 21(3):332-333.
  • White TL, Hermer-Vasquez L, Beaudin S, Strangle D, Strupp BJ. 2000. Long-term effects of early postnatal lead exposure on extradimensional shift performance. Neurotoxicol Teratol A22:456.

1999

  • Driscoll LL, Gardiner SA, Beaudin S, Strupp BJ. 1999. Enduring effects of early lead exposure in a vigilence test: Contribution of cholinergic alterations. Neurotoxicol Teratol 21(3):331.
  • Driscoll LL, Strupp BJ. 1999. Lead exposure produces subsensitivity to the motor but not the mnemonic effects of MK-801. Society for Neuroscience Abstracts 25(1):634.
  • Driscoll LL, Wu JJ, Zurich KJ, Strupp BJ. 1999. Chronic lead exposure alters explicit memory function. Toxicol Sci 48(1-S):360.
  • Strupp BJ, Morgan RE, Garavan H. 1999. Enduring effects of early lead exposure: Assessment of sustained attention, inhibitory control, and information processing speed. Toxicol Sci 48(1-S):360.

1998

  • Cremin JD, Olsen HE, Seaton C, Woolard D, Littles S, Strupp BJ, Smith DR. 1998. Effects of neo-natal Pb exposure on protein kinase C (PKC) in rat brain regions. Toxicol Sci 42:27.
  • Cremin JD, Olsen HE, Strupp BJ, Smith DR. 1998. Pb Effects on brain region protein kinase C (PKC) in a neo-natal rat model. Neurotoxicol Teratol 20:362-363.
  • Driscoll LL, Gilbert ME, Strupp BJ. 1998. Cholinergic and noradrenergic modulation of long-term explicit memory are altered by chronic low-level lead exposure. Neurotoxicol Teratol 20:362-363.
  • Higley M, Hermer-Vasquez L, Strupp BJ. 1998. Recovery of function following early lesions of the amygdala. Society for Neuroscience Abstracts 24(2):
  • Patton L, Smith DR, Strupp BJ. 1998. Evaluation of succimer chelation in removing lead (Pb) from brain, bone, kidney and blood: Effects of treatment duration and body lead burden. Neurotoxicol Teratol 20:363.
  • Smith DR, Bayer LE, Strupp BJ. 1998. Efficacy of succimer chelation for reducing brain Pb levels in a rodent model. Environ Res 78:168-176. PMID:9719621
  • Strupp BJ, Patton L, Smith DR. 1998. Evaluation of succimer chelation for reducing brain-Pb levels in a rodent model. Toxicol Sci 42:27.

1997

  • Driscoll LL, Gilbert ME, Strupp BJ. 1997. Lead-exposed rats are more sensitive to the effects of scopolamine on long-term explicit memory. Society for Neuroscience Abstracts 23:215.
  • Higley M, Garavan H, Morgan RE, Finlay BL, Strupp BJ. 1997. A preliminary test of the hypothesis that impaired stimulus-response-reward learning in lead-exposed rats reflects amygdala dysfunction. Society for Neuroscience Abstracts 23:2210.
  • Hilson J, Strupp BJ. 1997. Analyses of response patterns clarify lead effects in olfactory reversal and extra-dimensional shift tasks: Assessment of inhibitory control, associative ability, and memory. Behav Neurosci 111(3):532-542.
  • Strupp BJ, Diamond A. 1997. Assessing cognitive function in animal models of mental retardation. Ment Retard Dev Disabil Res Rev 2:216-226.

1996

  • Alber SA, Strupp BJ. 1996. An in-depth analysis of lead effects in a delayed spatial alternation task: assessment of mnemonic effects, side bias and proactive interference. Neurotoxicol Teratol 18(1):3-15. PMID:8700040
  • Garavan H, Strupp BJ. 1996. Enduring alterations in response patterns in rats exposed to lead (Pb) during early development: I. Two-choice olfactory serial reversal task. Neurotoxicol Teratol 18(3):336.
  • Morgan RE, Strupp BJ. 1996. Enduring attentional effects of early lead (Pb) exposure. Neurotoxicol Teratol 18(3):341-342.
  • Sawyer RL, Strupp BJ. 1996. Enduring alterations in response patterns in rats exposed to lead (Pb) during early development: II. Three-choice olfactory serial reversal task and an extra-dimensional shift (EDS). Neurotoxicol Teratol 18(3):336.
  • Strupp BJ, Hilson J. 1996. An analysis of response patterns sheds light on the basis of impaired learning of reversal and nonreversal shifts in rats chronically exposed to lead (Pb). Neurotoxicol Teratol 18:341.

1995

  • Bayer LE, Strupp BJ. 1995. Attentional effects of idazoxan in lead-exposed and control rats. Society for Neuroscience Abstracts 21:31.
  • Bunsey MD, Strupp BJ. 1995. Idazoxan alters distractibility: evidence that endogenous norepinephrine plays a role in response inhibition. Behav Neurosci 109:903-911.
  • Koger S, Strupp BJ, Alber SA, Levitsky DA. 1995. A fine-grained analysis of lead (Pb) effects in a delayed spatial alternation task: assessment of mnemonic effects, side bias, and proactive interference. Neurotoxicol Teratol 17:381.
  • Levitsky DA, Strupp BJ. 1995. Malnutrition and the brain; Changing concepts, changing concerns. J Nutr 125:2233S-2243S. PMID:7542703
  • Morgan RE, Strupp BJ, Levitsky DA, Alber SA. 1995. Effects of low-level lead (Pb) exposure on reaction time and learning rate in a visual discrimination task: Evidence for the specificity of the cognitive impairment. Neurotoxicol Teratol 17:383.
  • Strupp BJ, Braga-Costa T, Drazen S, Wu C, Raffman H, Alber SA, Bayer LE, Levitsky DA. 1995. Altered attention, declarative memory, and reward efficacy in rats exposed to lead during early development: evidence for dysfunction of prefrontal cortex, hippocampus, and nucleus accumbens. Society for Neuroscience Abstracts 21:1940.
  • Strupp BJ, Hilson J, Drazen S, Levitsky DA, Alber SA. 1995. Specificity of the cognitive dysfunction produced by low-level lead (Pb) exposure. Neurotoxicol Teratol 17:373.
  • Strupp BJ, Levitsky DA. 1995. Enduring cognitive effects of early malnutrition: A theoretical re-appraisal. J Nutr 125:2221S-2232S. PMID:7542704
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