Superfund Research Program

Julian I. Schroeder

University of California-San Diego
Division of Biological Sciences, 0116
9500 Gilman Drive
La Jolla, California 92093-0116
Phone: 858-534-7759
Fax: 858-534-7108
Email: jischroeder@ucsd.edu

Projects

• University of California-San Diego: Molecular Mechanisms of Heavy Metal Detoxification and Accumulation in Plants (2000-2017)
• University of California-San Diego: Molecular Mechanisms of Heavy Metal Detoxification and Engineering Accumulation in Plants (2017-2023)

Research Briefs

• 260 - Identifying Mechanisms for Regulating Gas Exchange in Plants
• 192 - Discovery of the Key to Metal Accumulation in Plants
• 110 - Resistance to Heavy Metals - a Possible Tool for Phytoremediation

Patents

• A Genomic Scale Artificial microRNA Library as a Tool to Investigate the Functionally Redundant Gene Space in Arabidopsis thaliana
• ABAleon, A Genetically Encoded Nano-Biosensor to Visualize Time-Resolved Abscisic Acid Concentration Changes in Vivo
• Composition for Phytochelatin Transport
• Compositions and Methods for Mediating Plant Stomatal Development in Response to Carbon Dioxide and Applications for Engineering Drought Tolerance in Plants
• Controlling CO2-Regulated Stomatal Apertures, Water Transpiration and Water Use Efficiency in Plants
• Enhancing Drought, Salinity and Cold Tolerance in Plants and Trees
• Improved Methods to Extract Signaling Proteins from Crop Plants
• Mechanisms that Mediate Interference Signaling Between Pathogen Immunity Signaling and ABA-Induced Abiotic Stress Resistance Signaling
• Method to Improve Drought Tolerance in Plants
• Novel Genes Mediating Plant Stomatal Development and Applications for Engineering Drought Tolerance
• Phytochelatin Synthases and Uses Therefor
• Plant CO2 Sensors, Nucleic Acids Encoding Them, and Methods for Making and Using Them
• Plant Sensors, Nucleic Acids Encoding Them, and Methods for Making and Using Them
• Yeast Transporters that Mediate Cadmium and Arsenic Tolerance

Publications

2023

• Kushwaha P, Tran A, Quintero D, Song M, Yu Q, Yu RT, Downes M, Evans RM, Babst-Kostecka AA, Schroeder JI, Maier RM. 2023. Zinc accumulation in Atriplex lentiformis is driven by plant genes and the soil microbiome. Sci Total Environ 899:165667. doi:10.1016/j.scitotenv.2023.165667 PMID:37478925

2022

• Waadt R, Seller CA, Hsu P, Takahashi Y, Munemasa S, Schroeder JI. 2022. Plant hormone regulation of abiotic stress responses. Nat Rev Mol Cell Biol doi:10.1038/s41580-022-00479-6 PMID:35513717

2021

• Jalakas P, Takahashi Y, Waadt R, Schroeder JI, Merilo E. 2021. Molecular mechanisms of stomatal closure in response to rising vapour pressure deficit. New Phytol 232(2):doi:10.1111/nph.17592 PMID:34197630 (ahead of print)
• Jobe TO, Yu Q, Hauser F, Xie Q, Meng Y, Maassen T, Kopriva S, Schroeder JI. 2021. The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana. FEBS Lett 595(12):1696-1707. doi:10.1002/1873-3468.14096 PMID:33960401 PMCID:PMC8238853
• Xie Q, Yu Q, Jobe TO, Pham A, Ge C, Guo Q, Liu J, Liu H, Zhang H, Zhao Y, Xue S, Hauser F, Schroeder JI. 2021. An amiRNA screen uncovers redundant CBF and ERF34/35 transcription factors that differentially regulate arsenite and cadmium responses. Plant Cell Environ 44(5):1692-1706. doi:10.1111/pce.14023 PMID:33554343 PMCID:PMC8068611
• Yu Q, Zhang Z, Wang M, Scavo A, Schroeder JI, Qiu B. 2021. Identification and characterization of SaeIF1 from the eukaryotic translation factor SUI1 family in cadmium hyperaccumulator Sedum alfredii. Planta 253:12. doi:10.1007/s00425-020-03539-3 PMID:33389204 PMCID:PMC7847809
• Zhang L, Takahashi Y, Schroeder JI. 2021. Protein kinase sensors: An overview of new designs for visualizing kinase dynamics in single plant cells. Plant Physiol 187(2):527-536. doi:10.1093/plphys/kiab277

2020

• Cooper AM, Felix D, Alcantara F, Zaslavsky I, Work A, Watson P, Pezzoli K, Yu Q, Zhu D, Scavo A, Zarabi Y, Schroeder JI. 2020. Monitoring and mitigation of toxic heavy metals and arsenic accumulation in food crops: a case study of an urban community garden. Plant Direct 4(1):e00198. doi:10.1002/pld3.198 PMID:31956855 PMCID:PMC6957986
• Hsu P, Dubeaux G, Takahashi Y, Schroeder JI. 2020. Signaling mechanisms in abscisic acid-mediated stomatal closure. The Plant Journal 15:doi:10.1111/tpj.15067 PMID:33145840
• Schulze S, Dubeaux G, Ceciliato PH, Munemasa S, Nuhkat M, Yarmolinsky D, Aguilar J, Diaz R, Azoulay-Shemer T, Steinhorst L, Offenborn JN, Kudla J, KOLLIST H, Schroeder JI. 2020. A role for calcium-dependent protein kinases in differential CO2- and ABA-controlled stomatal closing and low CO2-induced stomatal opening in Arabidopsis. New Phytologist 15:doi:10.1111/nph.17079 PMID:33187027
• Takahashi Y, Zhang J, Hsu P, Ceciliato PH, Dubeaux G, Munemasa S, Ge C, Zhao Y, Hauser F, Schroeder JI. 2020. MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and rapid osmotic stress response. Nat Commun 11(1):12. doi:10.1038/s41467-019-13875-y PMID:31896774 PMCID:PMC6940395

2019

• Bailey-Serres J, Parker JE, Ainsworth EA, Oldroyd GE, Schroeder JI. 2019. Genetic strategies for improving crop yields. Nature 575:109-118. doi:10.1038/s41586-019-1679-0 PMID:31695205 PMCID:PMC7024682
• Ceciliato PH, Zhang J, Liu Q, Shen X, Hu H, Liu C, Shaffner AR, Schroeder JI. 2019. Intact leaf gas exchange provides a robust method for measuring the kinetics of stomatal conductance responses to abscisic acid and other small molecules in Arabidopsis and grasses. Plant Methods 15:10. doi:10.1186/s13007-019-0423-y PMID:31019545 PMCID:PMC6472101
• Hauser F, Ceciliato PH, Lin Y, Guo D, Gregerson J, Abbasi N, Youhanna D, Park J, Dubeaux G, Shani E, Poomchongkho N, Schroeder JI. 2019. A seed resource for screening functionally redundant genes and isolation of new mutants impaired in CO2 and ABA responses. J Exp Bot 70:641-65. doi:10.1093/jxb/ery363 PMID:30346611 PMCID:PMC6322574
• Park J, Kim T, Takahashi Y, Schwab R, Dressano K, Stephan AB, Ceciliato PH, Ramirez E, Garin V, Huffaker A, Schroeder JI. 2019. Chemical genetic identification of a lectin receptor kinase that transduces immune responses and interferes with abscisic acid signaling. The Plant Journal doi:10.1111/tpj.14232 PMID:30659683 PMCID:PMC6488365

2018

• Dangl J, Osbourn A, Orzaez D, Li Z, Long SP, Schroeder JI. 2018. What Is the Next Frontier in Plant Engineering?. Cell 174(3):499-500. doi:10.1016/j.cell.2018.07.012 PMID:30053421
• Hsu P, Takahashi Y, Munemasa S, Merilo E, Laanemets K, Waadt R, Patar D, KOLLIST H, Schroeder JI. 2018. Abscisic acid-independent stomatal CO2 signal transduction pathway and convergence of CO2 and ABA signaling downstream of OST1 kinase. Proc Natl Acad Sci U S A 115:E9971-E9980. doi:10.1073/pnas.1809204115 PMID:30282744 PMCID:PMC6196521
• Li Z, Takahashi Y, Scavo A, Brandt B, Nguyen D, Rieu P, Schroeder JI. 2018. Abscisic acid-induced degradation of Arabidopsis guanine nucleotide exchange factor requires calcium-dependent protein kinases. Proc Natl Acad Sci U S A 115(19):E4522-E4531. doi:10.1073/pnas.1719659115 PMID:29686103 PMCID:PMC5948973
• Toldsepp K, Zhang J, Takahashi Y, Sindarovska y, Horack H, Ceciliato PH, Koolmeister K, Wang Y, Vaahtera L, Jakobson L, Park J, BROSCHE M, KOLLIST H, Schroeder JI. 2018. Mitogen-activated protein kinases MPK4 and MPK12 are key components mediating CO2-induced stomatal movements. The Plant Journal 96:1018-1035. doi:10.1111/tpj.14087 PMID:30203878 PMCID:PMC6261798
• Zhang Y, Nasser V, Pisanty O, Omary M, Wulff N, Donato MD, Tal I, Hauser F, Hao P, Roth O, Fromm H, Schroeder JI, Geisler M, Nour-Eldin HH, Shani E. 2018. A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport. Nat Commun 9:4204. doi:10.1038/s41467-018-06410-y PMID:30310073 PMCID:PMC6182007

2017

• Azoulay-Shemer T, Hsu P, Schroeder JI. 2017. Seeing is believing. Nat Plants 3(10):765-766. doi:10.1038/s41477-017-0025-5 PMID:28970562 PMCID:28970562

2016

• Aleman F, Yazaki J, Lee M, Takahashi Y, Kim AY, Li Z, Kinoshita T, Ecker JR, Schroeder JI. 2016. An ABA-increased interaction of the PYL6 ABA receptor with MYC2 transcription factor: a putative link of ABA and JA signaling. Sci Rep 6:28941. doi:10.1038/srep28941 PMID:27357749 PMCID:PMC4928087
• Engineer C, Hashimoto-Sugimoto M, Negi J, Israelsson-Nordstrom M, Azoulay-Shemer T, Rappel WJ, Iba K, Schroeder JI. 2016. CO2 sensing and CO2 regulation of stomatal conductance: advances and open questions. Trends Plant Sci 21(1):16-30. doi:10.1016/j.tplants.2015.08.014 PMID:26482956 PMCID:PMC4707055
• Stephan AB, Kunz H, Yang E, Schroeder JI. 2016. Rapid hyperosmotic-induced Ca2+ responses in Arabidopsis thaliana exhibit sensory potentiation and involvement of plastidial KEA transporters. Proc Natl Acad Sci U S A 113(35):E5242-E5249. doi:10.1073/pnas.1519555113 PMID:27528686 PMCID:PMC5024618
• Suzuki K, Yamaji N, Costa A, Okuma E, Kobayashi NI, Kashiwagi T, Katsuhara M, Wang C, Tanoi K, Murata Y, Schroeder JI, Ma JF, Horie T. 2016. OsHKT1;4-mediated Na(+) transport in stems contributes to Na(+) exclusion from leaf blades of rice at the reproductive growth stage upon salt stress. BMC Plant Biol 16:22. doi:10.1186/s12870-016-0709-4 PMID:26786707 PMCID:PMC4719677
• Wang C, Hu H, Qin X, Zeise B, Xu D, Rappel WJ, Boron W, Schroeder JI. 2016. Reconstitution of CO2 regulation of SLAC1 anion channel and function of CO2-permeable PIP2;1 aquaporin as carbonic anhydrase 4 interactor. Plant Cell 28(2):568-582. doi:10.1105/tpc.15.00637 PMID:26764375 PMCID:PMC4790870
• Yamamoto Y, Negi J, Wang C, Isogai Y, Schroeder JI, Iba K. 2016. The transmembrane region of guard cell SLAC1 channels perceives CO2 signals via an ABA-independent pathway in Arabidopsis. Plant Cell 28(2):557-567. doi:10.1105/tpc.15.00583 PMID:26764376 PMCID:PMC4790869
• Yazaki J, Galli M, Kim AY, Nito K, Aleman F, Chang KN, Carvunis A, Quan R, Nguyen H, Song L, Alvarez J, Huang SC, Chen H, Ramachandran N, Altmann S, Gutierrez RA, Hill DE, Schroeder JI, Chory J, LaBaer J, Vidal M, Braun P, Ecker JR. 2016. Mapping transcription factor interactome networks using HaloTag protein arrays. Proc Natl Acad Sci U S A 113(29):E4238-E4247. doi:10.1073/pnas.1603229113 PMID:27357687 PMCID:PMC4961138
• Zhang Z, Xie Q, Jobe TO, Kau AR, Wang C, Li Y, Qiu B, Wang Q, Mendoza-Cozatl DG, Schroeder JI. 2016. Identification of AtOPT4 as a plant glutathione transporter. Mol Plant 9(3):481-484. doi:10.1016/j.molp.2015.07.013 PMID:26283048 PMCID:PMC5139274

2015

• Azoulay-Shemer T, Palomares A, Bagheri A, Israelsson-Nordstrom M, Engineer C, Bargmann BO, Stephan AB, Schroeder JI. 2015. Guard cell photosynthesis is critical for stomatal turgor production, yet does not directly mediate CO2 - and ABA-induced stomatal closing. Plant J 83(4):567-581. doi:10.1111/tpj.12916 PMID:26096271 PMCID:PMC4532624
• Brandt B, Munemasa S, Wang C, Nguyen D, Yong T, Yang PG, Poretsky E, Belknap TF, Waadt R, Aleman F, Schroeder JI. 2015. Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells. Elife 4:doi:10.7554/eLife.03599 PMID:26192964 PMCID:PMC4507714
• Keinath NF, Waadt R, Brugman R, Schroeder JI, Grossmann G, Schumacher K, Krebs M. 2015. Live Cell Imaging with R-GECO1 Sheds Light on flg22- and Chitin-Induced Transient [Ca(2+)]cyt Patterns in Arabidopsis. Mol Plant 8(8):1188-1200. doi:10.1016/j.molp.2015.05.006 PMID:26002145 PMCID:PMC5134422
• Munemasa S, Hauser F, Park J, Waadt R, Brandt B, Schroeder JI. 2015. Mechanisms of abscisic acid-mediated control of stomatal aperture. Curr Opin Plant Biol 28:154-162. doi:10.1016/j.pbi.2015.10.010 PMID:26599955 PMCID:PMC4679528
• Waadt R, Hsu P, Schroeder JI. 2015. Abscisic acid and other plant hormones: methods to visualize distribution and signaling. Bioessays 37(12):1338-1349. doi:10.1002/bies.201500115 PMID:26577078 PMCID:PMC4677054

2014

• Deinlein U, Stephan AB, Horie T, Luo W, Xu G, Schroeder JI. 2014. Plant salt-tolerance mechanisms. Trends Plant Sci 19(6):371-379. doi:10.1016/j.tplants.2014.02.001 PMID:24630845 PMCID:PMC4041829
• Engineer C, Ghassemian M, Anderson JC, Peck SC, Hu H, Schroeder JI. 2014. Carbonic anhydrases, EPF2 and a novel protease mediate CO2 control of stomatal development. Nature 513(7517):246-250. doi:10.1038/nature13452 PMID:25043023 PMCID:PMC4274335
• Kunz H, Gierth M, Herdean A, Satoh-Cruz M, Kramer DM, Spetea C, Schroeder JI. 2014. Plastidial transporters KEA1, -2, and -3 are essential for chloroplast osmoregulation, integrity, and pH regulation in Arabidopsis. Proc Natl Acad Sci U S A 111(20):7480-7485. doi:10.1073/pnas.1323899111 PMID:24794527 PMCID:PMC4034250
• Mendoza-Cozatl DG, Xie Q, Akmakjian GZ, Jobe TO, Patel AU, Stacey MG, Song L, Demoin DW, Jurisson SS, Stacey G, Schroeder JI. 2014. OPT3 is a component of the iron-signaling network between leaves and roots and misregulation of OPT3 leads to an over-accumulation of cadmium in seeds. Mol Plant 7(9):1455-1469. doi:10.1093/mp/ssu067 PMID:24880337 PMCID:PMC4153440
• Song W, Mendoza-Cozatl DG, Lee Y, Schroeder JI, Ahn S, Lee H, Wicker T, Martinoia E. 2014. Phytochelatin-metal(loid) transport into vacuoles shows different substrate preferences in barley and Arabidopsis. Plant Cell Environ 37(5):1192-1201. doi:10.1111/pce.12227 PMID:24313707 PMCID:PMC4123957
• Stephan AB, Schroeder JI. 2014. Plant salt stress status is transmitted systemically via propagating calcium waves. Proc Natl Acad Sci U S A 111(17):6126-6127. doi:10.1073/pnas.1404895111 PMID:24737890 PMCID:PMC4036006
• Waadt R, Hitomi K, Nishimura N, Hitomi C, Adams SR, Getzoff ED, Schroeder JI. 2014. FRET-based reporters for the direct visualization of abscisic acid concentration changes and distribution in Arabidopsis. Elife 3:e01739. doi:10.7554/eLife.01739 PMID:24737861 PMCID:PMC3985518

2013

• Hauser F, Chen W, Deinlein U, Chang K, Ossowski S, Fitz J, Hannon GJ, Schroeder JI. 2013. A genomic-scale artificial microRNA library as a tool to investigate the functionally redundant gene space in Arabidopsis. Plant Cell 25(8):2848-2863. doi:10.1105/tpc.113.112805 PMID:23956262 PMCID:PMC3784584
• McDowell SC, Akmakjian GZ, Sladek C, Mendoza-Cozatl DG, Morrissey JB, Saini N, Mittler R, Baxter I, Salt DE, Ward JM, Schroeder JI, Guerinot ML, Harper JF. 2013. Elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown under varying soil conditions. PLoS One 8(5):e63014. doi:10.1371/journal.pone.0063014 PMID:23671651 PMCID:PMC3646034
• Schroeder JI, Delhaize E, Frommer WB, Guerinot ML, Harrison MJ, Herrera-Estrella L, Horie T, Kochian LV, Munns R, Nishizawa NK, Tsay Y, Sanders D. 2013. Using membrane transporters to improve crops for sustainable food production. Nature 497:60-66. doi:10.1038/nature11909 PMID:23636397 PMCID:PMC3954111

2012

• Jobe TO, Sung D, Akmakjian GZ, Pham AL, Komives EA, Mendoza-Cozatl DG, Schroeder JI. 2012. Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glutathione-deficient y-ECS and glutathione synthetase mutants impaired in cadmium-induced sulfate assimilation. Plant J 70:783-795. doi:10.1111/j.1365-313X.2012.04924.x PMID:22283708 PMCID:PMC4688143

2011

• Bohmer M, Schroeder JI. 2011. Quantitative transcriptomic analysis of abscisic acid-induced and reactive oxygen species-dependent expression changes and proteomic profiling in Arabidopsis suspension cells. Plant J 67(1):105-118. doi:10.1111/j.1365-313X.2011.04579.x PMID:21426425 PMCID:PMC3125488
• Hauser F, Waadt R, Schroeder JI. 2011. Evolution of abscisic acid synthesis and signaling mechanisms. Current Biology 21:R346-R355. doi:10.1016/j.cub.2011.03.015 PMID:21549957 PMCID:PMC3119208
• Horie T, Brodsky DE, Costa A, Kaneko T, Lo Schiavo F, Katsuhara M, Schroeder JI. 2011. K+ transport by the OsHKT2;4 transporter from rice with atypical Na+ transport properties and competition in permeation of K+ over Mg2+ and Ca2+ ions. Plant Physiol 156:1493-1507. doi:10.1104/pp.110.168047 PMID:21610181 PMCID:PMC3135959
• Jannat R, Uraji M, Morofuji M, Islam MM, Bloom RE, Nakamura Y, McClung CR, Schroeder JI, Mori IC, Murata Y. 2011. Roles of intracellular hydrogen peroxide accumulation in abscisic acid signaling in Arabidopsis guard cells. J Plant Physiol 168(16):1919-1926. doi:10.1016/j.jplph.2011.05.006 PMID:21665322 PMCID:PMC4073789
• Mendoza-Cozatl DG, Jobe TO, Hauser F, Schroeder JI. 2011. Long-distance transport, vacuolar sequestration, tolerance, and transcriptional responses induced by cadmium and arsenic. Curr Opin Plant Biol 14:554-562. doi:10.1016/j.pbi.2011.07.004 PMID:21820943 PMCID:PMC3191310
• Xue S, Yao X, Luo W, Jha D, Tester M, Horie T, Schroeder JI. 2011. AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells. PLoS One 6(9):e24725.. doi:10.1371/journal.pone.0024725 PMID:21931830 PMCID:PMC3170383

2010

• Costa A, Drago I, Behera S, Zottini M, Pizzo P, Schroeder JI, Pozzan T, Schiavo F. 2010. H2O2 in plant peroxisomes: an in vivo analysis uncovers a Ca(2+)-dependent scavenging system. Plant J 62(5):760-772. doi:10.1111/j.1365-313X.2010.04190.x PMID:20230493 PMCID:PMC2884081
• Mendoza-Cozatl DG, Zhai Z, Jobe TO, Akmakjian GZ, Song W, Limbo O, Russell MR, Kozlovskyy VI, Martinoia E, Vatamaniuk OK, Russell P, Schroeder JI. 2010. Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance. J Biol Chem 285(52):40416-40426. doi:10.1074/jbc.M110.155408 PMID:20937798 PMCID:PMC3003340
• Nishimura N, Sarkeshik A, Park S, Wang A, Carvalho PC, Lee S, Caddell DF, Cutler SR, Chory J, Yates JR, Schroeder JI, Nito K. 2010. PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis. Plant J 61(2):290-299. doi:10.1111/j.1365-313X.2009.04054.x PMID:19874541 PMCID:PMC2807913
• Pyo Y, Gierth M, Schroeder JI, Cho M. 2010. High-affinity K(+) transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment and postgermination growth under low-potassium conditions. Plant Physiol 153(2):863-875. doi:10.1104/pp.110.154369 PMID:20413648 PMCID:PMC2879780
• Song W, Park J, Mendoza-Cózatl D, Suter-Grotemeyer M, Shim D, Hortensteiner S, Geisler M, Weder B, Rea PA, Rentsch D, Schroeder JI. 2010. Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters. Proc Natl Acad Sci U S A 107(49):21187-21192. doi:10.1073/pnas.1013964107 PMID:21078981 PMCID:PMC3000282
• Yao X, Horie T, Xue S, Leung H, Katsuhara M, Brodsky DE, Wu Y, Schroeder JI. 2010. Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells. Plant Physiol 152(1):341-355. doi:10.1104/pp.109.145722 PMID:19889878 PMCID:PMC2799368

2009

• Horie T, Hauser F, Schroeder JI. 2009. HKT transporter-mediated salinity resistance mechanisms in Arabidopsis and monocot crop plants. Trends Plant Sci 14(12):660-668. doi:10.1016/j.tplants.2009.08.009 PMID:19783197 PMCID:PMC2787891
• Maser P, Schroeder JI, Ward JM. 2009. Plant ion channels: gene families, physiology, and functional genomics analyses. Annu Rev Physiol 71:59-82. doi:10.1146/annurev.physiol.010908.163204 PMID:18842100 PMCID:PMC4790454
• Nishimura N, Schroeder JI, Getzoff ED, Cutler SR, Hitomi C, Rambo RP, Arvai AS, Hitomi K. 2009. Structural mechanism of abscisic acid binding and signaling by dimeric PYR1. Science 326(5958):1373-1379. doi:10.1126/science.1181829 PMID:19933100 PMCID:PMC2835493
• Sung D, Kim T, Komives EA, Mendoza-Cózatl D, Schroeder JI. 2009. ARS5 is a component of the 26S proteasome complex, and negatively regulates thiol biosynthesis and arsenic tolerance in Arabidopsis. Plant J 59(5):802-813. doi:10.1111/j.1365-313X.2009.03914.x PMID:19453443 PMCID:PMC2830867

2008

• Horie T, Sugawara M, OKUNOU K, NAKAYAMA H, Schroeder JI, Shinmyo A, Yoshida K. 2008. Functions of HKT transporters in sodium transport in roots and in protecting leaves from salinity stress. Plant Biotechnology 25:233-239.
• Kim Y, Kim D, Shim D, Song W, Lee J, Schroeder JI, Kim S, Moran| N, Lee Y. 2008. Expression of the novel wheat gene TM20 confers enhanced cadmium tolerance to bakers' yeast. J Biol Chem 283:15893-15902. doi:10.1074/jbc.M708947200 PMID:18411273 PMCID:PMC2414300
• Mendoza-Cózatl D, Butko E, Springer F, Torpey JW, Komives EA, Kehr J, Schroeder JI. 2008. Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassica napus A role for thiol-peptides in the long-distance transport of cadmium and the effect of cadmium on iron translocation. Plant J 54(2):249-259. doi:10.1111/j.1365-313X.2008.03410.x PMID:18208526 PMCID:PMC2839885
• VAHISALU T, KOLLIST H, Wang Y, Nishimura N, Chan W, Valerio G, LAMMINMÄKI A, BROSCHE M, DESIKAN R, Schroeder JI, KANGASJÄRVI J, MOLDAU H. 2008. SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling. Nature 452:487-491. PMID:18305484

2007

• Horie T, Costa A, Kim T, Han M, Horie R, Leung H, Miyao A, Hirochika H, An G, Schroeder JI. 2007. Rice OsHKT2;1 transporter mediates large Na+ influx component into K+-starved roots for growth. EMBO J 26(12):3003-14. PMID:17541409

2006

• Chen A, Komives EA, Schroeder JI. 2006. An improved grafting technique for mature Arabidopsis plants demonstrates long-distance shoot-to-root transport of phytochelatins in Arabidopsis. Plant Physiol 141(1):108-120. doi:10.1104/pp.105.072637 PMID:16531489 PMCID:PMC1459314
• Nguyen V, Schroeder JI. 2006. The role of reactive oxygen species in hormonal responses. Plant Physiol 141(2):323-329. PMID:16760482
• Platten JD, Cotsaftis O, Berthomieu P, Bohnert H, Davenport RJ, Fairbairn DJ, Horie T, Leigh RA, Lin H, Luan S, Maser P, Pantoja O, Rodriguez-Navarro A, Schachtman DP, Schroeder JI, Sentenac H, Uozumi N, Very A, Zhu J, Dennis ES, Tester M. 2006. Nomenclature for HKT transporters, key determinants of plant salinity tolerance. Trends Plant Sci 11(8):372-374. PMID:16809061
• Schroeder JI, Kuhn JM. 2006. Plant biology: abscisic acid in bloom. Nature 439(7074):277-278. doi:10.1038/439277a PMID:16421556
• Schroeder JI, Nambara E. 2006. A quick release mechanism for abscisic acid. Cell 126(6):1023-1025. PMID:16990126

2005

• Sunarpi, Horie T, Motoda J, Kubo M, Yang H, Yoda K, Horie R, Chan W, Leung H, Hattori K, Konomi M, Osumi M, Yamagami M, Schroeder JI, Uozumi N. 2005. Enhanced salt tolerance mediated by AtHKT1 transporter-induced Na+ unloading from xylem vessels to xylem parenchyma cells. Plant J 44(6):928-938. PMID:16359386

2004

• Gong J, Waner DA, Horie T, Li S, Horie R, Abid KB, Schroeder JI. 2004. Microarray-based rapid cloning of an ion accumulation deletion mutant in Arabidopsis thaliana. Proc Natl Acad Sci U S A 101(43):15404-15409. PMID:15486089
• Li Y, Dhankher OP, Carreira L, Lee DA, Chen A, Schroeder JI, Balish RS, Meagher RB. 2004. Overexpression of phytochelatin synthase in Arabidopsis leads to enhanced arsenic tolerance and cadmium hypersensitivity. Plant and Cell Physiology 45(12):1787-1797. PMID:15653797
• Schroeder JI, Mori IC. 2004. Reactive oxygen species activation of plant Ca2+ channels. A signaling mechanism in polar growth, hormone transduction, stress signaling, and hypothetically mechanotransduction. Plant Physiol 135(2):702-708. PMID:15208417
• Thomine S, Schroeder JI. 2004. Plant metal transporters with homology to proteins of the NRAMP family. In: The NRAMP Family. Landes Bioscience, Georgetown, TX. pp.11.
• Wycisk K, Kim EJ, Schroeder JI, Kramer U. 2004. Enhancing the first enzymatic step in the histidine biosynthesis pathway increases the free histidine pool and nickel tolerance in Arabidopsis thaliana. FEBS Lett 578(1-2):128-134. PMID:15581629

2003

• Gong J, Lee DA, Schroeder JI. 2003. Long-distance root-to-shoot transport of phytochelatins and cadmium in Arabidopsis. Proc Natl Acad Sci U S A 100(17):10118-10123. PMID:12909714
• Lahner B, Gong J, Mahmoudian M, Smith EL, Abid KB, Rogers EE, Guerinot ML, Harper JF, Ward JM, McIntyre L, Schroeder JI, Salt DE. 2003. Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana. Nat Biotechnol 21(10):1215-1221. PMID:12949535
• Lee DA, Chen A, Schroeder JI. 2003. Ars1, an Arabidopsis mutant exhibiting increased tolerance to arsenate and increased phosphate uptake. Plant J 35(5):637-646. PMID:12940956
• Schroeder JI. 2003. Knockout of the guard cell K+ out channel and stomatal movements. Proc Natl Acad Sci U S A 100(9):4976-4977. PMID:12704226
• Thomine S, Lelievre F, Debarbieux E, Schroeder JI, Barbier-Brygoo H. 2003. AtNRAMP3, a multispecific vacuolar metal transporter involved in plant responses to iron deficiency. Plant J 34(5):685-695. PMID:12787249

2002

• Allen GJ, Murata Y, Chu SP, Nafisi M, Schroeder JI. 2002. Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltransferase mutant era1-2. Plant Cell 14(7):1649-1662. PMID:12119381 PMCID:PMC150713
• Beachy R, Bennetzen JL, Chassy BM, Chrispeels M, Chory J, Ecker JR, Noel JP, Kay SA, Dean C, Lamb C, Jones J, Santerre CR, Schroeder JI, Umen J, Yanofsky M, Wessler S, Zhao Y, Parrott W. 2002. Divergent perspectives on GM food. Nat Biotechnol 20(12):1195-1196. PMID:12454665
• Kuchitsu K, Ward JM, Allen GJ, Schelle I, Schroeder JI. 2002. Loading acetoxymethyl ester fluorescent dyes into the cytoplasam of Arabidopsis and Commelina guard cells. New Phytologist 153:527-533.
• Lee DA, Schroeder JI. 2002. Heavy metal stress. In: Arabidopsis - A Laboratory Manual. Cold Spring Harbor Laboratory Press, pp.75-77.
• Maser P, Eckelman B, Vaidyanathan R, Horie T, Fairbairn DJ, Kubo M, Yamagami M, Yamaguchi K, Nishimura M, Uozumi N, Robertson W, Sussman MR, Schroeder JI. 2002. Altered shoot/root Na+ distribution and bifurcating salt sensitivity in Arabidopsis by genetic disruption of the Na+ transporter AtHKT1. FEBS Lett 531(2):157-161. PMID:12417304
• Maser P, Hosoo Y, Goshima S, Horie T, Eckelman B, Yamada K, Yoshida K, Bakker EP, Shinmyo A, Oiki S, Schroeder JI, Uozumi N. 2002. Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in four-loop-per-subunit HKT transporters from plants. Proc Natl Acad Sci U S A 99(9):6428-6433. PMID:11959905

2001

• Clemens S, Schroeder JI, Degenkolb T. 2001. Caenorhabditis elegans express a functional phytochelatin synthase. FEBS J 268(13):3640-3643.
• Ghassemian M, Waner DA, Tchieu J, Gribskov M, Schroeder JI. 2001. An integrated Arabidopsis annotation database for Affymetrix Genechip data analysis, and tools for regulatory motif searches. Trends Plant Sci 6(10):448-449. PMID:11590042
• LaCombe B, Becker D, Hedrich R, DeSalle R, Hollman M, Kwak JM, Schroeder JI, Le Novere N, Nam HG, Spalding EP, Tester M, Turano FJ, Chiu J, Coruzzi G. 2001. The identity of plant glutamate receptors. Science 292:1486-1487. PMID:11379626
• Murata Y, Pei Z, Mori IC, Schroeder JI. 2001. ABA activation of plasma membrane Ca2+ channels in guard cells requires cytosolic NAD(P)H and is differentially disrupted upstream and downstream of reactive oxygen species production in the abi1-1 and abi2-1 PP2C mutants. Plant Cell 13:2513-2523.
• Schroeder JI, Kwak JM, Allen GJ. 2001. Guard cell abscisic acid signalling and engineering drought hardiness in plants. Nature 410:327-330. PMID:11268200

2000

• Pei Z, Murata Y, Benning G, Thomine S, Klusener B, Allen GJ, Grill E, Schroeder JI. 2000. Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells. Nature 406:731-734. PMID:10963598
• Thomine S, Wang R, Ward JM, Crawford NM, Schroeder JI. 2000. Cadmium and iron transport by members of a plant metal transporter family in Arabidopsis with homology to Nramp genes. Proc Natl Acad Sci U S A 97(9):4991-4996. PMID:10781110

1999

• Clemens S, Kim EJ, Neumann D, Schroeder JI. 1999. Tolerance to toxic metals by a gene family of phytochelatin synthases from plants and yeast. EMBO J 18(12):3325-3333. PMID:10369673
• Ou YC, Thompson SA, Ponce RA, Schroeder JI, Kavanagh TJ, Faustman EM. 1999. Induction of the cell cycle regulatory gene p21 (Waf1, Cip1) following methylmercury exposure in vitro and in vivo. Toxicol Appl Pharmacol 157:203-212. PMID:10373404