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Your Environment. Your Health.

Person Details: A. Jay Gandolfi

Superfund Research Program

A. Jay Gandolfi

University of Arizona
Department of Pharmacology
College of Pharmacy
PO Box 210207
Tucson, Arizona 85721-0207
Phone: 520-626-6696
Fax: 520-626-2466
Email: gandolfi@pharmacy.arizona.edu

Projects

Research Briefs

Hazardous Waste Sites

Iron King Mine and Humboldt Smelter

  • University of Arizona: Critical Events in the Transformation of Human Bladder Cells by Low-Level Arsenic Exposure

Publications

2020

  • Lopez-Carillo L, Gamboa-Loira B, Gandolfi A, Cebrian ME. 2020. Inorganic arsenic methylation capacity and breast cancer by immunohistochemical subtypes in northern Mexican women. Environ Res doi:10.1016/j.envres.2020.109361
  • Michel-Ramirez G, Recio-Vega R, Lantz RC, Gandolfi A, Olivas-Calderon E, Chau BT, Amistadi M. 2020. Assessment of YAP gene polymorphisms and arsenic interaction in Mexican women with breast cancer. J Appl Toxicol 40(3):342-351. doi:10.1002/jat.3907 PMID:31631368 PMCID:PMC7012748

2018

  • Garcia-Rico L, Meza-Figueroa D, Gandolfi A, del Rivero CI, Martinez-Cinco MA, Meza-Montenegro MM. 2018. Health risk assessment and urinary excretion of children exposed to arsenic through drinking water and soils in Sonora, Mexico. Biol Trace Elem Res doi:10.1007/s12011-018-1347-5 PMID:29721859

2017

  • Michel-Ramirez G, Recio-Vega R, Ocampo-Gomez G, Palacios-Sanchez E, Delgado-Macias M, Delgado-Gaona M, Lantz RC, Gandolfi A, Gonzalez-Cortes. 2017. Association between YAP expression in neoplastic and non-neoplastic breast tissue with arsenic urinary levels. J Appl Toxicol 37:1195-1202. doi:10.1002/jat.3481 PMID:28524356
  • Moreno Ramirez D, Vea L, Field JA, Baker PB, Gandolfi A, Maier RM. 2017. Transferable training modules: Building environmental education opportunities with and for Mexican Community Health Workers (Promotores de Salud). Journal of Family Community Health 40:306-315. doi:10.1097/FCH.0000000000000111 PMID:28323677 PMCID:PMC5562520 (accepted for publication)
  • Oliva-Gonzalez C, Uresti-Rivera E, Galicia-Cruz O, Jasso-Robles F, Gandolfi A, Escudero-Lourdes C. 2017. The tumor suppressor phosphatase and tensin homolog protein (PTEN) is negatively regulated by NF-kappa b p50 homodimers and involves histone 3 methylation/deacetylation in UROtsa cells chronically exposed to monomethylarsonous acid. Toxicol Lett 280:92-98. doi:10.1016/j.toxlet.2017.08.013 PMID:28823542

2016

  • Lopez-Carrillo L, Gamboa-Loira B, Becerra W, Hernandez-Alcaraz C, Hernandez-Ramirez RU, Gandolfi A, Franco-Marina F, Cebrian ME. 2016. Dietary micronutrient intake and its relationship with arsenic metabolism in Mexican women. Environ Res 151:445-450. doi:10.1016/j.envres.2016.08.015 PMID:27565879
  • Recio-Vega R, Gonzalez-Cortes, Olivas-Calderon E, Gandolfi A, Michel-Ramirez G, Lantz RC. 2016. Association between polymorphisms in arsenic metabolism genes and urinary arsenic methylation profiles in girls and boys chronically exposed to arsenic. Environ Mol Mutagen 57(7):516-525. doi:10.1002/em.22026 PMID:27327299 PMCID:PMC4980171

2015

  • Olivas-Calderon E, Recio-Vega R, Gandolfi A, Lantz RC, Gonzalez-Cortes, Gonzalez-De Alba C, Froines JR, Espinosa-Fematt JA. 2015. Lung inflammation biomarkers and lung function in children chronically exposed to arsenic. Toxicol Appl Pharmacol 287(2):161-167. doi:10.1016/j.taap.2015.06.001 PMID:26048584 PMCID:PMC4751871
  • Ramirez-Andreotta M, Brusseau ML, Artiola JF, Maier RM, Gandolfi A. 2015. Building a co-created citizen science program with gardeners neighboring a superfund site: The Gardenroots case study. Int Public Health J 7(1):PMID:25954473 PMCID:PMC4420190
  • Recio-Vega R, Gonzalez-Cortes, Olivas-Calderon E, Lantz RC, Gandolfi A, Gonzalez-De Alba C. 2015. In utero and early childhood exposure to arsenic decreases lung function in children. J Appl Toxicol 35(4):358-366. doi:10.1002/jat.3023 PMID:25131850 PMCID:PMC4750377

2014

  • Burchiel SW, Lauer FT, Beswick EJ, Gandolfi A, Parvez F, Liu K, Hudson LG. 2014. Differential susceptibility of human peripheral blood T cells to suppression by environmental levels of sodium arsenite and monomethylarsonous acid. PLoS One 9:8. doi:10.1371/journal.pone.0109192 PMID:25271956 PMCID:PMC4182801
  • Ezeh PC, Lauer FT, MacKenzie D, McClain S, Liu K, Hudson LG, Gandolfi A, Burchiel SW. 2014. Arsenite selectively inhibits mouse bone marrow lymphoid progenitor cell development in vivo and in vitro and suppresses humoral immunity in vivo. PLoS One 9(4):e93920. doi:10.1371/journal.pone.0093920 PMID:24714590 PMCID:PMC3979857
  • Medeiros MK, Le TM, Troup D, Novak P, Gandolfi A. 2014. Expression of selected pathway-marker genes in human urothelial cells exposed chronically to a non-cytotoxic concentration of monomethylarsonous acid. Toxicol Rep 1:421-434. doi:10.1016/j.toxrep.2014.07.004 PMID:25177542 PMCID:PMC4144464
  • Ramirez-Andreotta M, Brusseau ML, Artiola JF, Maier RM, Gandolfi A. 2014. Building a co-created citizen science program with gardeners neighboring a superfund site: The Gardenroots case study. Chapter 15 in: Public Health: Improving Health via Inter-Professional Collaborations. Nova Science Publishers, pp.183-201.
  • Ramirez-Andreotta M, Brusseau ML, Artiola JF, Maier RM, Gandolfi A. 2014. Environmental research translation: enhancing interactions with communities at contaminated sites. Sci Total Environ 497-498:651-664. doi:10.1016/j.scitotenv.2014.08.021 PMID:25173762 PMCID:PMC4186773
  • Zhou X, Sun X, Mobarak C, Gandolfi A, Burchiel SW, Hudson LG, Liu K. 2014. Differential binding of monomethylarsonous acid compared to arsenite and arsenic trioxide with zinc finger peptides and proteins. Chem Res Toxicol 27(4):690-698. doi:10.1021/tx500022j PMID:24611629 PMCID:PMC3998772

2013

  • Diaz-Villasenor A, Cruz L, Cebrian A, Hernandez-Ramirez RU, Hiriart M, Garcia-Vargas GG, Bassol S, Sordo M, Gandolfi A, Klimecki WT, Cebrian ME, Ostrosky-Wegman P, Lopez-Carillo L. 2013. Arsenic exposure and calpain-10 polymorphisms impair the function of pancreatic beta-cells in humans: A pilot study of risk factors for T2DM. PLoS One 8:doi:10.1371/journal.pone.0051642 PMID:23349674 PMCID:PMC3551951
  • Gilbert-Diamond D, Li Z, Perry AE, Spencer SK, Gandolfi A, Karagas MR. 2013. A population-based case-control study of urinary arsenic species and squamous cell carcinoma in New Hampshire, USA. Environ Health Perspect 121(10):1154-1160. doi:10.1289/ehp.1206178 PMID:23872349 PMCID:PMC3801199

2012

  • Canet MJ, Hardwick RN, Lake AD, Kopplin MJ, Scheffer GL, Klimecki WT, Gandolfi A, Cherrington NJ. 2012. Altered arsenic disposition in experimental nonalcoholic fatty liver disease. Drug Metab Dispos 40(9):1817-1824. doi:10.1124/dmd.112.046177 PMID:22699396 PMCID:PMC3422539
  • Escudero-Lourdes C, Wu T, Camarillo JM, Gandolfi A. 2012. Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid MMA(III) -induced malignant transformation of urothelial cells. Toxicol Appl Pharmacol 258:10-18. doi:10.1016/j.taap.2011.10.002 PMID:22015448 PMCID:PMC3254786
  • Gandolfi A, Lau SS, Yassine H, Kimzey MJ, Galligan MA, Stump CS. 2012. Adjusting for urinary creatinine overestimates arsenic concentrations in diabetics. Cardiorenal Med 2:26-32. PMID:22493600 PMCID:PMC3318926
  • Medeiros MK, Zheng XH, Novak P, Wnek SM, Chyan V, Escudero-Lourdes C, Gandolfi A. 2012. Global gene expression changes in human urothelial cells exposed to low-level monomethylarsonous acid. Toxicology 291:102-12. doi:10.1016/j.tox.2011.11.002 PMID:22108045 PMCID:PMC3245769
  • Meza-Montenegro MM, Gandolfi A, Valenzuela-Quintanar AI, Balderas-Cortes JJ, Yanez-Estrada L, Gutierrez-Coronado ML, Cuevas-Robles A. 2012. Exposure assessment of organochlorine pesticides, arsenic, and lead in chilren from the major agricultureal areas in Sonora, Mexico. Arch Environ Contam Toxicol doi:10.1007/s00244-012-9846-4 PMID:23254566 PMCID:PMC4023507

2011

  • Gilbert-Diamond D, Cottingham KL, Gruber JF, Punshon T, Sayarath V, Gandolfi A, Baker E, Jackson BP, Folt CL, Karagas MR. 2011. Rice consumption contributes to arsenic exposure in US women. Proc Natl Acad Sci U S A 108(51):20656-20660. doi:10.1073/pnas.1109127108 PMID:22143778 PMCID:PMC3251121
  • Wnek SM, Kuhlman CL, Camarillo JM, Medeiros MK, Liu KJ, Lau SS, Gandolfi A. 2011. Interdependent genotoxic mechanisms of monomethylarsonous acid: Role of ROS-induced DNA damage and poly(ADP-ribose) polymerase-1 inhibition in the malignant transformation of urothelial cells. Toxicol Appl Pharmacol 257:1-13. doi:10.1016/j.taap.2011.08.029 PMID:21925530 PMCID:PMC3220758

2010

  • Escudero-Lourdes C, Medeiros MK, Cardenas-Gonzalez MC, Wnek SM, Gandolfi A. 2010. Low level exposure to monomethyl arsonous acid-induced the over-production of inflammation-related cytokines and the activation of cell signals associated with tumor progression in a urothelial cell model. Toxicol Appl Pharmacol 244(2):162-173. doi:10.1016/j.taap.2009.12.029 PMID:20045430 PMCID:PMC2846965
  • Wnek SM, Jensen TJ, Severson PL, Futscher BW, Gandolfi A. 2010. Monomethylarsonous acid produces irreversible events resulting in malignant transformation of a human bladder cell line following 12 weeks of low-level exposure. Toxicol Sci 116(1):44-57. doi:10.1093/toxsci/kfq106 PMID:20375083 PMCID:PMC2886861

2009

2008

  • Eblin KE, Bredfeldt TG, Gandolfi A. 2008. Immortalized human urothelial cells as a model of arsenic-induced bladder cancer. Toxicology 248(2-3):67-76. doi:10.1016/j.tox.2008.03.020 PMID:18456381
  • Eblin KE, Hau AM, Jensen TJ, Gandolfi A, Futscher BW. 2008. The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: acute studies. Toxicology 250(1):47-54. doi:10.1016/j.tox.2008.05.018 PMID:18588940 PMCID:PMC2567114
  • Jensen TJ, Eblin KE, Gandolfi A, Novak P. 2008. Epigenetic remodeling during arsenical-induced malignant transformation. Carcinogenesis 29:1500-8. PMID:18448484
  • Meza MM, Kopplin MJ, Burgess JL, Gandolfi A. 2008. Urinary arsenic methylation profile in children exposed to low arsenic levels through drinking water. Toxicol Sci 90:957-970. doi:10.1080/02772240701782140

2007

  • Eblin KE, Bredfeldt TG, Buffington SE, Gandolfi A. 2007. Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis. Toxicol Sci 95(2):321-330. PMID:17093206
  • Meza MM, Gandolfi A, Klimecki WT. 2007. Developmental and genetic modulation of arsenic biotransformation: a gene by environment interaction?. Toxicol Appl Pharmacol 222(3):381-387. doi:10.1016/j.taap.2006.12.018 PMID:17306849 PMCID:PMC2040165
  • Wang X, Sun Z, Chen W, Eblin KE, Gandolfi A, Zhang DD. 2007. Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity. Toxicol Appl Pharmacol 225(2):206-13. PMID:17765279

2006

  • Bredfeldt TG, Jagadish B, Eblin KE, Mash EA, Gandolfi A. 2006. Monomethylarsonous acid induces transformation of human bladder cells. Toxicol Appl Pharmacol 216(1):69-79. PMID:16806342
  • Eblin KE, Bowen ME, Cromey DW, Bredfeldt TG, Mash EA, Lau SS, Gandolfi A. 2006. Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture. Toxicol Appl Pharmacol 217(1):7-14. PMID:16930658
  • Peraza MA, Cromey DW, Carolus B, Carter DE, Gandolfi A. 2006. Morphological and functional alterations in human proximal tubular cell line induced by low level inorganic arsenic: evidence for targeting of mitochondria and initiated apoptosis. J Appl Toxicol 26(4):356-67. PMID:16773642

2005

  • Billings KE, Bredfeldt TG, Zheng XH, Kopplin MJ, Watts GS, Sens DA, Mash EA, Gandolfi A. 2005. Characterization of human bladder urothelial cells malignantly transformed by arsenite. Environ Health Perspect 84(S1):31.
  • Bredfeldt TG, Billings KE, Zheng XH, Mash EA, Domann FE, Lau SS, Sens DA, Gandolfi A. 2005. Arsenite and monomethyl arsonous acid-induced toxicity ion human urothelial cells. Environ Health Perspect 84(S1):31.
  • Kirkpatrick DS, Weldon SF, Tsaprailis G, Liebler DC, Gandolfi A. 2005. Proteomic identification of ubiquitinated proteins from human cells expressing His-tagged ubiquitin. Proteomics 5(8):2104-2111. PMID:15852347
  • Meza MM, Yu L, Rodriguez YY, Guild M, Thompson D, Gandolfi A, Klimecki WT. 2005. Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children. Environ Health Perspect 113(6):775-781. PMID:15929903
  • Sierra-Alvarez R, Field JA, Cortinas I, Feijoo G, Moreira MT, Kopplin MJ, Gandolfi A. 2005. Anaerobic microbial mobilization and biotransformation of arsenate adsorbed onto activated alumina. Water Res 39(1):199-209. doi:10.1016/j.watres.2004.09.014 PMID:15607178
  • Zheng XH, Bredfeldt TG, Watts GS, Gandolfi A. 2005. Toxicogenomical study on human bladder epithelium exposed to arsenic. Environ Health Perspect 84(S1):238.

2004

  • Bredfeldt TG, Kopplin MJ, Gandolfi A. 2004. Effects of arsenite on UROtsa cells: low-level arsenite causes accumulation of ubiquitinated proteins that is enhanced by reduction in cellular glutathione levels. Toxicol Appl Pharmacol 198(3):412-418. PMID:15276421
  • Field JA, Sierra-Alvarez R, Cortinas I, Feijoo G, Moreira MT, Kopplin MJ, Gandolfi A. 2004. Facile reduction of arsenate in methanogenic sludge. Biodegradation 15(3):185-196. PMID:15228076
  • Meza MM, Kopplin MJ, Burgess JL, Gandolfi A. 2004. Arsenic drinking water exposure and urinary excretion among adults in the Yaqui Valley, Sonora, Mexico. Environ Res 96(2):119-126. doi:10.1016/j.envres.2003.08.010 PMID:15325872
  • Nyman DW, Stratton MS, Kopplin MJ, Dalkin BL, Nagle RB, Gandolfi A. 2004. Selenium and selenomethionine levels in prostate cancer patients. Cancer Detect Prev 28(1):8-16. PMID:15041072

2003

  • Carter DE, Aposhian HV, Gandolfi A. 2003. The metabolism of inorganic arsenic oxides, gallium arsenide, and arsine: a toxicochemical review. Toxicol Appl Pharmacol 193(3):309-334. PMID:14678742
  • Gandolfi A. 2003. In vitro techniques in screening and mechanistic studies: organ perfusion, slices, and nephron components. In: Toxicology and the Kidney - Third Edition.
  • Kirkpatrick DS, Dale KV, Catania JM, Gandolfi A. 2003. Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK 293 cells. Toxicol Appl Pharmacol 186(2):101-109. PMID:12639501
  • Kirkpatrick DS, Weldon SF, Tsaprailis G, Liebler DC, Gandolfi A. 2003. Qualitative and quantitative analysis of changes in the ubiquitin pathway in human cells using LC-MS/MS. Mol Cell Proteomics
  • Peraza MA, Carter DE, Gandolfi A. 2003. Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2). Cell Biol Toxicol 19(4):253-264. PMID:14686617
  • Quanrud DM, Arnold RG, Lansey KE, Begay CK, Ela WP, Gandolfi A. 2003. Fate of effluent organic matter during soil aquifer treatment: biodegradability, chlorine reactivity and genotoxicity. J Water Health 1(1):33-44. PMID:15384271
  • Sierra-Alvarez R, Field JA, Cortinas I, Kopplin MJ, Gandolfi A. 2003. Microbial reduction and mobilization of arsenate under landfill conditions. In: Proceedings of the 7th International Symposium on In Situ and On-Site Bioremediation. Orlando, FL.
  • Yenal U, Field JA, Sierra-Alvarez R, Kopplin MJ, Begay CK, Gandolfi A. 2003. Anaerobic biodegradation of organoarsenical pesticides, methyarsonic acid (MMAV) and dimethylarsinic acid (DMAV). In: Proceedings of the Southwest Environmental Health Sciences Center(SWEHSC)/Superfund Science Fair, May 20, 2003. Tucson, AZ.
  • Zheng XH, Watts GS, Vaught S, Gandolfi A. 2003. Low-level arsenate induced gene expression in HEK 293 cells. Toxicology 187(1):39-48. PMID:12679051

2002

  • Dale KV, Liebler DC, Gandolfi A. 2002. Identification of ubiquitin-conjugated proteins using lc-ms techniques: potential molecular indicators of toxic insults. Environ Health Perspect 66:A1083.
  • Peraza MA, Kopplin MJ, Carter DE, Gandolfi A. 2002. Inorganic arsenic biotransformation and mitochondrial toxicity in HK-2 human proximal tubular cells. Environ Health Perspect 66:A403.
  • Sipes IG, McQueen CA, Gandolfi A. 2002. Inorganic arsenic biotransformation and mitochondrial toxicity in HK-2 human proximal tubular cells. In: Comprehensive Toxicology. Vol. 14, Cellular and Molecular Toxicology. Elsevier-Academic Press, pp.644.

2001

  • Dale KV, Liebler DC, Gandolfi A. 2001. Identification of ubiquitin-conjugated proteins using lc-ms techniques: potential molecular indicators of toxic insults. In: Proceedings of the Symposium on Gene Expression, December 2-4. Bethesda, MD.
  • Gandolfi A. 2001. Hazardous Waste Risk and Remediation in the Southwest. In: Proceedings of the Superfund Basic Research Program Annual Meeting: Assessing Risks of Hormonally Active Agents, December 10-12, 2001. University of Florida Conference Center, Gainsville, FL.
  • Gandolfi A. 2001. Organ Perfusion, Slices and Nephron Components in Toxicology of the Kidney. In: In Vitro Techniques in Screening and Mechanistic Studies (3rd edition). Raven Press,
  • Wijeweera JB, Gandolfi A, Parrish AR, Lantz RC. 2001. Sodium arsenite enhances AP-1 and NFKB DNA binding and induces stress protein expression in precision-cut rat lung slices. Toxicol Sci 61(2):283-294. PMID:11353137

2000

  • Catania JM, Gandolfi A. 2000. Increased ubiquitin-conjugated proteins following low-level arsenite exposure. In: Proceedings of the SEGH (Society for Environmental Geochemistry and Health) Fourth International Conference on Arsenic Exposure and Health Effects, June 18-22. San Diego, CA.
  • Zheng XH, Gandolfi A, Wilson CL, Parrish AR. 2000. Analysis of differential expressed genes in rabbit renal cortical slices exposed to arsenic compounds. In: Proceedings of the SEGH (Society for Environmental Geochemistry and Health) Fourth International Conference on Arsenic Exposure and Health Effects, June 18-22. San Diego, CA.
  • Zheng XH, Parrish AR, Gandolfi A. 2000. Analysis of differentially-expressed genes in rabbit renal cortical slices exposed to arsenic compounds. Southwest Environmental Health Sciences Center Newsletter
  • Zheng XH, Wilson CL, Parrish AR, Gandolfi A. 2000. Differential gene expression in rabbit renal cortical slices exposed to arsenic compounds. Toxicol Sci 54:

1999

  • Keith RL, Gandolfi A, McIntyre LC, Ashbaugh MD, Fernando Q. 1999. Analysis of heavy metal deposition in biological tissue by sectional mapping using m-PIXE. Nucl Instrum Methods Phys Res A 149:167-176.
  • Parrish AR, Zheng XH, Turney KD, Younis HS, Gandolfi A. 1999. Enhanced transcription factor DNA binding and gene expression induced by arsenite or arsenate in renal slices. Toxicol Sci 50:98-105. PMID:10445758
  • Turney KD, Parrish AR, Gandolfi A. 1999. Selective activation in the MAPK pathway by Hg(II). Toxicol Sci 48:331.
  • Turney KD, Parrish AR, Orozco J, Gandolfi A. 1999. Selective activation in the MAPK pathway by Hg(II) in precision-cut rabbit renal cortical slices. Toxicol Appl Pharmacol 160(3):262-270. PMID:10544060
  • Wei H, Qiu L, Divine KK, Ashbaugh MD, McIntyre LC, Fernando Q, Gandolfi A. 1999. Toxicity and transport of three synthesized mercury-thiol-complexes in isolated rabbit renal proximal tubule suspensions. Drug Chem Toxicol 22(2):323-341. PMID:10234470
  • Zheng XH, Parrish AR, Turney KD, Younis HS, Gandolfi A. 1999. Arsenite [AS(III)] and arsenate [AS(V)] enhance DNA binding of the AP-1 and elk-1 transcription factors and c-jun and c-fos gene expression in precision-cut renal slices. Toxicol Sci 48:351.

1998

  • Gandolfi A, Parrish AR, Turney KD, Zheng XH. 1998. Molecular alteration in renal tissue following in vitro exposure to nanomolar levels of Hg(II), As(III) or As(V). In: Proceedings of the Superfund Basic Research Program (SBRP) Conference, 1998. Boston, MA.
  • Keith RL, McIntyre LC, Ashbaugh MD, Fernando Q, Gandolfi A. 1998. Characterization of heavy metal deposition in rabbit renal tissue using micro-proton induced x-ray emission. In: Proceedings of the Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.
  • Parrish AR, Fisher RL, Bral CM, Burghardt RC, Gandolfi A, Brendel K, Ramos KS. 1998. Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver slices. Toxicol Appl Pharmacol 152:302-308. PMID:9852999
  • Qiu L, Lott JR, Fernando Q, Ashbaugh MD, McIntyre LC, Keith RL, Wei H, Gandolfi A. 1998. The PIXE and micro-PIXE facility at the University of Arizona. In: Proceedings of the Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.
  • Turney KD, Parrish AR, Gandolfi A. 1998. Changes in AP-1 and c-jun expression in precision-cut rabbit renal cortical slices following exposure to Hg(II). Environ Health Perspect 31:380.
  • Turney KD, Parrish AR, Gandolfi A. 1998. Increased AP-1 and c-jun in renal slices following exposure to Hg(II). In: Proceedings of the Symposium on Risk Considerations for Environmental Health and Safety. The University of Arizona, Tucson, AZ.
  • Wei H, Qiu L, Divine KK, Ashbaugh MD, McIntyre LC, Fernando Q, Gandolfi A. 1998. Accumulation of HgCl2 and three synthesized Hg-S-conjugates in isolated rabbit renal proximal tubule suspensions. In: Proceedings of the Superfund Basic Research Program: A Decade of Improving Health through Multi-Disciplinary Research. Chapel Hill, NC.
  • Wijeweera JB, Gandolfi A, Zheng XH. 1998. Interactive toxicity and stress protein expression by vinylidene chloride and monochloroacetate in precision-cut liver slices. Environ Health Perspect 106(Suppl.6):1319-1323. PMID:9860887
  • Zheng XH, Younis HS, Turney KD, Parrish AR, Gandolfi A. 1998. Molecular alterations in renal cortical slices following exposure to sub-toxic levels of arsenic. Toxicol Sci 42:323.
  • Zheng XH, Younis HS, Turney KD, Parrish AR, Gandolfi A. 1998. Molecular alterations in renal slices following arsenite exposure. In: Proceedings of the Symposium on Risk Considerations for Environmental Health and Safety. The University of Arizona, Tucson, AZ.

1997

  • Keith RL, Gandolfi A, McIntyre LC, Ashbaugh MD, Fernando Q. 1997. Use of the nuclear microprobe at the University of Arizona for the study of heavy metal deposition in rabbit renal tissue. Nucl Instrum Methods Phys Res A 130:358-361.
  • Keith RL, McIntyre LC, Ashbaugh MD, Fernando Q, Gandolfi A. 1997. Characterization of heavy metal deposition in rabbit renal tissue using micro-proton induced x-ray emission. Environ Health Perspect 36:185.
  • Keith RL, Setiarahardjo I, Fernando Q, Aposhian HV, Gandolfi A. 1997. Utilization of renal slices to evaluate the efficacy of chelators to remove mercury from the kidney. Toxicology 116:67-75. PMID:9020508
  • McIntyre LC, Leavitt JA, Ashbaugh MD, Borgardt J, Keith RL, Gandolfi A, Qiu L, Lott JR, Fernando Q. 1997. The nuclear microprobe at the University of Arizona. Nucl Instrum Methods Phys Res A 130(1-4):45-50. doi:10.1016/S0168-583X(97)00177-8
  • Wei H, Qiu L, Divine KK, Ashbaugh MD, McIntyre LC, Fernando Q, Gandolfi A. 1997. Accumulation of HgCl2 and three synthesized Hg-S-conjugates in isolated rabbit renal proximal tubule suspensions. Environ Health Perspect 36:185.
  • Wei H, Qiu L, Divine KK, Ashbaugh MD, McIntyre LC, Fernando Q, Gandolfi A. 1997. Accumulation of HgCl2 and three synthesized Hg-S-conjugates in isolated rabbit renal proximal tubule suspensions. In: Proceedings of the TCE Symposium, The University of Arizona, Tucson, AZ.
  • Wijeweera JB, Zheng XH, Gandolfi A. 1997. Interactive toxicity of MCA and VDC in precision-cut rat livers slices. In: Proceedings of the Current Issues in Chemical Mixtures Conference. Colorado State University, Ft. Collins, CO.

1996

  • Gandolfi A, Brendel K, Fernando Q. 1996. Preparation and use of precision-cut renal cortical slices in renal toxicology. In: Methods of Renal Toxicology. CRC Press, Inc., Boca Raton, FL. pp.109-122.
  • Keith RL, Gandolfi A, McIntyre LC, Ashbaugh MD, Qiu L, Lott JR, Fernando Q. 1996. Use of the nuclear microprobe at the University of Arizona for the study of heavy metal deposition in rabbit renal tissue. In: Proceedings of the International Conference on Nuclear Microprobe Technology and Applications. Sante Fe, NM.
  • Keith RL, Leavitt JA, McIntyre LC, Fernando Q, Gandolfi A. 1996. Assessment of heavy metal accumulation in renal tissue using micro-proton induced x-ray emission (mu-PIXE). Environ Health Perspect 30:258.
  • Wei H, Divine KK, Gandolfi A. 1996. Uptake and toxicity of HgCl2 and synthesized Hg(SG)2 and Hg(CYS)2 in isolated rabbit renal proximal tubule suspensions. Environ Health Perspect 30:129.

1995

  • Burton CA, Hatlelid K, Divine KK, Carter DE, Fernando Q, Brendel K, Gandolfi A. 1995. Glutathione effects on toxicity and uptake of mercuric chloride and sodium arsenite in rabbit renal cortical slices. Environ Health Perspect 103(Suppl.1):81-84. PMID:7621807
  • Gandolfi A, Brendel K, Fisher RL, Michaud J. 1995. Use of tissue slices in chemical mixture toxicology and interspecies investigations. Toxicology 105(2-3):285-290. PMID:8571365
  • Hasal SJ, Aposhian HV, Gandolfi A, Brendel K. 1995. Human and rabbit renal cortical slices in aerated submersion culture as a model to evaluate heavy metal chelators. Environ Health Perspect 15:310.
  • Keith RL, Leavitt JA, McIntyre LC, Fernando Q, Gandolfi A. 1995. Use of micro-proton induced x-ray emission (mu-PIXE) for heavy metal analysis. Environ Health Perspect 15:106.
  • Keith RL, McGuinness SJ, Gandolfi A, Lowe TP, Chen Q, Fernando Q. 1995. Interaction of metals during their uptake and accumulation in rabbit renal cortical slices. Environ Health Perspect 103(Suppl.1):77-80. PMID:7621806
  • Wijeweera JB, Thomas CM, Gandolfi A, Brendel K. 1995. Sodium arsenite and heat shock induce stress proteins in precision-cut liver slices. Toxicology 104:35-45. PMID:8560500

1993

  • Lowe TP, Chen Q, Fernando Q, Keith RL, Gandolfi A. 1993. Elemental analysis of renal slices by proton-induced X-ray emission. Environ Health Perspect 101:302. PMID:8275986
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