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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

University of California-Berkeley

Superfund Research Program

Biomarkers of Genetic Damage in Human Cells

Project Leader: Martyn T. Smith
Grant Number: P42ES004705
Funding Period: 1995 - 2006

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Project Summary (1995-2000)

This project continues to develop new biomarkers of genetic damage for use in studying human populations. The overall goal is to develop highly predictive biomarkers of leukemia risk with the aim of understanding the causes of leukemia in human populations. Leukemias and lymphomas are the fourth most common type of cancer in the United States and often cluster near Superfund sites and other hazardous facilities. New methods to determine what risk factors play a role in leukemia development and to predict which environmental chemicals might cause leukemia will be generated. Collaborations with investigators from Projects 4 and 6 will be undertaken to better understand the role of different risk factors in childhood leukemia.

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