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Mount Sinai School of Medicine

Superfund Research Program

Lead Mobilization During Pregnancy and Lactation in Urban Women

Project Leader: Jacqueline M. Moline
Grant Number: P42ES007384
Funding Period: 1995 - 2001

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Project Summary (1995-2000)

This project provides quantitative data on the hypothesis that maternal lead stores can be mobilized during pregnancy and lactation, and may potentially adversely affect maternal and fetal health. The working hypothesis of this project is that skeletal lead is mobilized during pregnancy and lactation, resulting in increased blood lead levels and decreased bone lead concentrations. In addition, the role of body iron stores on the mobilization of lead is investigated. Data from this study will provide a basis for the development of scientifically based recommendations for the prevention of lead poisoning in urban children and women.

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