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Your Environment. Your Health.

Project Publications: Michigan State University: Hepatotoxicant-Induced Immune Suppression through TGF-beta Release

Superfund Research Program

Hepatotoxicant-Induced Immune Suppression through TGF-beta Release

Project Leader: Norbert E. Kaminski
Grant Number: P42ES004911
Funding Period: 1995 - 2000

Learn More About the Grantee

Visit the grantee's eNewsletter page Visit the grantee's eNewsletter page



  • McKarns SC, Kaminski NE. 2000. TGF-beta(1) differentially regulates IL-2 expression and [H-3]-thymidine incorporation in CD3 epsilon mAb- and CD28 mAb-activated splenocytes and thymocytes. Immunopharmocology 48(2):101-115. PMID:10936508


  • Han SH, Yea SS, Jeon YJ, Yang K, Kaminski NE. 1998. Transforming growth factor-beta 1 (TGF-beta1) promotes IL-2 mRNA expression through the up-regulation of NF-kappaB, AP-1 and NF-AT in EL4 cells. J Pharmacol Exp Ther 287(3):1105-1112. PMID:9864299


  • Jeon YJ, Han SH, Yang K, Kaminski NE. 1997. Induction of transforming growth factor β1 transcription by carbon tetrachloride leads to the inhibition of T helper 2 cell associated lymphokines. Toxicol Appl Pharmacol 144:27-35.


  • Delaney B, Kaminski NE. 1996. Liver-Immune interactions induced by hepatic regeneration: Similarities between partial hepatectomy and chemically-mediated hepatotoxicity. In: Experimental Immunotoxicology. CRC Press Inc, Boca Raton, FL. pp.157-167.
  • Han SH, Jeon YJ, Yang K, Kaminski NE. 1996. Induction of interleukin 2 gene expression by tranforming growth factor β1 in the murine T-cell line, EL4.IL-2. In: Proceedings of the 11th Annual Symposium on Mechanisms of Immunotoxicology. Virginia Beach, VA.
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