Superfund Research Program
Development and Application of Integrated In Vitro and Cell-Based Bioassays
Project Leader: Michael S. Denison
Co-Investigator: Isaac N. Pessah
Grant Number: P42ES004699
Funding Period: 1995-2015
Project-Specific Links
Research Briefs
225 - Commercial Paper and Rubber Products Contain Activators of the Aryl Hydrocarbon Receptor -- Denison, Di Giulio
Release Date: 09/04/2013Common commercial and consumer products, including newspapers and rubber bands, contain chemicals that are recognized by the body as toxins, according to a collaborative study by researchers at the Duke University and University of California, Davis Superfund Research Program (SRP) Centers.
216 - New Highly Sensitive On-Chip Nanoparticle Immunoassay -- Kennedy
Release Date: 12/05/2012A breakthrough in bioassay technology allows detection of attomolar concentrations of biomolecules on a microchip. This new nanotechnology approach to detecting proteins and other compounds increases sensitivity more than 1,000-fold over conventional assays, and yet is affordable and easy to use.
213 - Widely Used Antibacterial Agents May Lead to Significant Health Concerns -- Pessah, Hammock
Release Date: 09/05/2012Researchers at UC Davis show that triclosan, a chemical widely used in antibacterial products, impairs heart and skeletal muscle activity in animal models. Other studies link another antibacterial agent, triclocarban, to changes in regulatory pathways in mice and in human cells.
204 - CALUX Generation 3 - Enhanced Sensitivity for Low Volume/Low Concentration Samples -- Denison
Release Date: 12/07/2011Firefly genes make the CALUX contaminant detection tool literally light up in the presence of dioxin and related chemicals. New advances make the tool 10- to 100 times more sensitive.
150 - A New USEPA SW-846 Method 4435 for HAH Analysis -- Clark, Denison
Release Date: 06/06/20071 - Bioassay Developed for Detection of Dioxin-Like Chemicals -- Denison
Release Date: 08/07/1997