Superfund Research Program
Biomarkers of Exposure versus Effect: Improving the Scientific Basis for Risk Assessment
Project Leader: James A. Swenberg
Grant Number: P42ES005948
Funding Period: 1995-2018
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Research Briefs
- 258 - New Breakthrough in Understanding Gene Regulation -- Swenberg
Release Date: 06/01/2016A team of researchers at the University of North Carolina, Chapel Hill Superfund Research Program (UNC SRP) Center and Yale University developed a new method to study DNA modifications that led them to a paradigm-shifting discovery of a new mechanism of gene regulation in mouse cells. The new method and resulting discoveries are important breakthroughs that open new possibilities for understanding gene regulation in mice and humans, particularly during development.
- 201 - What a Difference a Methyl Group Makes -- Swenberg
Release Date: 09/07/2011Some proteins can turn genes on or off, like a light switch, by adding or removing a methyl group. Scientists are uncovering how these switches are wired, offering new insights for research on stem cells and cancer.
- 170 - Biomarkers to Investigate the Toxicity and Carcinogenicity of PHAHs -- Swenberg
Release Date: 02/04/2009 - 96 - DNA Adducts as Biomarkers of Exposure and Effect -- Swenberg
Release Date: 12/04/2002