Superfund Research Program
Control of Toxin and Obesity Induced Liver Fibrosis by B Cells
Project Leader: Michael Karin
Grant Number: P42ES010337
Funding Period: 2017-2023
- Project Summary
- 284 - Researchers Pinpoint Molecule Fueling Liver Cancer Development -- Karin
Release Date: 08/01/2018
New research out of the University of California, San Diego (UCSD) Superfund Research Program (SRP) Center explains how liver cells with DNA damage manage to survive and divide, fueling liver cancer. The study highlights the importance of a family of molecules called CD44 proteins, which are located on the surface of cells.
- 278 - Chronic Inflammation Suppresses Immune Cells that Fight Liver Cancer -- Karin
Release Date: 02/07/2018
Researchers at the University of California San Diego (UCSD) showed that chronic liver inflammation can promote cancer by suppressing one of the body's natural mechanisms to fight cancer development. The study, funded in part by the Superfund Research Program (SRP), explains the success of some types of cancer immunotherapy and suggests novel targets for new therapies.