Word
(http://tools.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/P01ES016738/format/word)
|
Excel
(http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/P01ES016738/format/word)
|
PDF
(http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/P01ES016738/format/word)
|
Excel
(http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/P01ES016738/format/word)
|
PDF
(http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/P01ES016738/format/word)
Who We Fund: Publication Detail
| Project Title: | La Jolla-Parkinson's Disease Center Grant |
|---|---|
| PI: | lipton, stuart a |
| Institution: | sanford-burnham medical research instit |
| Grant Number: | P01ES016738 |
| Count | Publication Title | Authors | Journal (Pub date) | Volume/Page | PubMed Link |
|---|---|---|---|---|---|
1 |
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. | Xiong, Hui; Wang, Danling; Chen, Linan; Choo, Yeun Su; Ma, Hong; Tang, Chengyuan; Xia, Kun; Jiang, Wei; Ronai, Ze'ev; Zhuang, Xiaoxi; Zhang, Zhuohua | J Clin Invest (2009 Mar) | 119 / 650-60 |
PubMed Citation
|
2 |
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. | Cho, Dong-Hyung; Nakamura, Tomohiro; Fang, Jianguo; Cieplak, Piotr; Godzik, Adam; Gu, Zezong; Lipton, Stuart A | Science (2009 Apr 3) | 324 / 102-5 |
PubMed Citation
|
3 |
Detection of protein ubiquitination. | Choo, Yeun Su; Zhang, Zhuohua | J Vis Exp (2009) | / |
PubMed Citation
|
4 |
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha- ... | Spencer, Brian; Potkar, Rewati; Trejo, Margarita; Rockenstein, Edward; Patrick, Christina; Gindi, Ryan; Adame, Anthony; Wyss-Coray, Tony; Masliah, Eliezer | J Neurosci (2009 Oct 28) | 29 / 13578-88 |
PubMed Citation
|
5 |
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neuro ... | Okamoto, Shu-ichi; Pouladi, Mahmoud A; Talantova, Maria; Yao, Dongdong; Xia, Peng; Ehrnhoefer, Dagmar E; Zaidi, Rameez; Clemente, Arjay; Kaul, Marcus; Graham, Rona K; Zhang, Dongxian; Vincent Chen, H-S; Tong, Gary; Hayden, Michael R; Lipton, Stuart A | Nat Med (2009 Dec) | 15 / 1407-13 |
PubMed Citation
|
6 |
Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alph ... | Koob, Andrew O; Ubhi, Kiren; Paulsson, Johan F; Kelly, Jeffery; Rockenstein, Edward; Mante, Michael; Adame, Anthony; Masliah, Eliezer | Exp Neurol (2010 Feb) | 221 / 267-74 |
PubMed Citation
|
7 |
Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: possible pharmacological ... | Nakamura, Tomohiro; Lipton, Stuart A | Cell Calcium (2010 Feb) | 47 / 190-7 |
PubMed Citation
|
8 |
Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfuncti ... | Gu, Zezong; Nakamura, Tomohiro; Lipton, Stuart A | Mol Neurobiol (2010 Jun) | 41 / 55-72 |
PubMed Citation
|
9 |
S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneratio ... | Nakamura, Tomohiro; Cieplak, Piotr; Cho, Dong-Hyung; Godzik, Adam; Lipton, Stuart A | Mitochondrion (2010 Aug) | 10 / 573-8 |
PubMed Citation
|
10 |
Direct reprogramming of mouse fibroblasts to neural progenitors. | Kim, Janghwan; Efe, Jem A; Zhu, Saiyong; Talantova, Maria; Yuan, Xu; Wang, Shufen; Lipton, Stuart A; Zhang, Kang; Ding, Sheng | Proc Natl Acad Sci U S A (2011 May 10) | 108 / 7838-43 |
PubMed Citation
|
11 |
Critical role of PINK1 in regulating Parkin protein levels in vivo. | Choo, Yeun Su; Tang, Chengyuan; Zhang, Zhuohua | Arch Neurol (2011 May) | 68 / 684-5 |
PubMed Citation
|
12 |
Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and n ... | Nakamura, T; Lipton, S A | Cell Death Differ (2011 Sep) | 18 / 1478-86 |
PubMed Citation
|
13 |
On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homo ... | Numajiri, Naoki; Takasawa, Kumi; Nishiya, Tadashi; Tanaka, Hirotaka; Ohno, Kazuki; Hayakawa, Wataru; Asada, Mariko; Matsuda, Hiromi; Azumi, Kaoru; Kamata, Hideaki; Nakamura, Tomohiro; Hara, Hideaki; Minami, Masabumi; Lipton, Stuart A; Uehara, Takashi | Proc Natl Acad Sci U S A (2011 Jun 21) | 108 / 10349-54 |
PubMed Citation
|
14 |
Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein ... | Tan, Jieqiong; Zhang, Tongmei; Jiang, Li; Chi, Jingwei; Hu, Dongshen; Pan, Qian; Wang, Danling; Zhang, Zhuohua | J Biol Chem (2011 Aug 26) | 286 / 29654-62 |
PubMed Citation
|
15 |
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. | Ambasudhan, Rajesh; Talantova, Maria; Coleman, Ronald; Yuan, Xu; Zhu, Saiyong; Lipton, Stuart A; Ding, Sheng | Cell Stem Cell (2011 Aug 5) | 9 / 113-8 |
PubMed Citation
|
16 |
S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptid ... | Qu, Jing; Nakamura, Tomohiro; Cao, Gang; Holland, Emily A; McKercher, Scott R; Lipton, Stuart A | Proc Natl Acad Sci U S A (2011 Aug 23) | 108 / 14330-5 |
PubMed Citation
|
17 |
Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock protein ... | Satoh, Takumi; Rezaie, Tayebeh; Seki, Masaaki; Sunico, Carmen R; Tabuchi, Takahito; Kitagawa, Tomomi; Yanagitai, Mika; Senzaki, Mutsumi; Kosegawa, Chihiro; Taira, Hideharu; McKercher, Scott R; Hoffman, Jennifer K; Roth, Gregory P; Lipton, Stuart A | J Neurochem (2011 Nov) | 119 / 569-78 |
PubMed Citation
|
18 |
Embargoed Publication: Title Restricted | Premkumar, Lakshmanane; Dobaczewska, Malgorzata K; Riedl, Stefan J | J Struct Biol (2011 Dec) | 176 / 414-8 |
PubMed Citation
|
19 |
MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian r ... | Cho, Eun-Gyung; Zaremba, Jeffrey D; McKercher, Scott R; Talantova, Maria; Tu, Shichun; Masliah, Eliezer; Chan, Shing Fai; Nakanishi, Nobuki; Terskikh, Alexey; Lipton, Stuart A | PLoS One (2011) | 6 / e24027 |
PubMed Citation
|
20 |
Aýý neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-asparta ... | You, Haitao; Tsutsui, Shigeki; Hameed, Shahid; Kannanayakal, Thomas J; Chen, Lina; Xia, Peng; Engbers, Jordan D T; Lipton, Stuart A; Stys, Peter K; Zamponi, Gerald W | Proc Natl Acad Sci U S A (2012 Jan 31) | 109 / 1737-42 |
PubMed Citation
|
21 |
Regulation of parkin and PINK1 by neddylation. | Choo, Yeun Su; Vogler, Georg; Wang, Danling; Kalvakuri, Sreehari; Iliuk, Anton; Tao, W Andy; Bodmer, Rolf; Zhang, Zhuohua | Hum Mol Genet (2012 Jun 1) | 21 / 2514-23 |
PubMed Citation
|
22 |
Isobaric tagging-based quantification by mass spectrometry of differentially regulated proteins in s ... | Banerjee, Sugato; Liao, Lujian; Russo, Rossella; Nakamura, Tomohiro; McKercher, Scott R; Okamoto, Shu-ichi; Haun, Florian; Nikzad, Rana; Zaidi, Rameez; Holland, Emily; Eroshkin, Alexey; Yates 3rd, John R; Lipton, Stuart A | Exp Neurol (2012 Aug) | 236 / 298-306 |
PubMed Citation
|
23 |
Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death i ... | Nakamura, Tomohiro; Cho, Dong-Hyung; Lipton, Stuart A | Exp Neurol (2012 Nov) | 238 / 12-21 |
PubMed Citation
|
24 |
S-nitrosylation of Cdk5: potential implications in amyloid-ýý-related neurotoxicity in Alzheimer dis ... | Qu, Jing; Nakamura, Tomohiro; Holland, Emily A; McKercher, Scott R; Lipton, Stuart A | Prion (2012 Sep-Oct) | 6 / 364-70 |
PubMed Citation
|
25 |
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. | Xiong, Hui; Wang, Danling; Chen, Linan; Choo, Yeun Su; Ma, Hong; Tang, Chengyuan; Xia, Kun; Jiang, Wei; Ronai, Ze'ev; Zhuang, Xiaoxi; Zhang, Zhuohua | J Clin Invest (2009 Mar) | 119 / 650-60 |
PubMed Citation
|
26 |
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. | Cho, Dong-Hyung; Nakamura, Tomohiro; Fang, Jianguo; Cieplak, Piotr; Godzik, Adam; Gu, Zezong; Lipton, Stuart A | Science (2009 Apr 3) | 324 / 102-5 |
PubMed Citation
|
27 |
Detection of protein ubiquitination. | Choo, Yeun Su; Zhang, Zhuohua | J Vis Exp (2009) | / |
PubMed Citation
|
28 |
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha- ... | Spencer, Brian; Potkar, Rewati; Trejo, Margarita; Rockenstein, Edward; Patrick, Christina; Gindi, Ryan; Adame, Anthony; Wyss-Coray, Tony; Masliah, Eliezer | J Neurosci (2009 Oct 28) | 29 / 13578-88 |
PubMed Citation
|
29 |
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neuro ... | Okamoto, Shu-ichi; Pouladi, Mahmoud A; Talantova, Maria; Yao, Dongdong; Xia, Peng; Ehrnhoefer, Dagmar E; Zaidi, Rameez; Clemente, Arjay; Kaul, Marcus; Graham, Rona K; Zhang, Dongxian; Vincent Chen, H-S; Tong, Gary; Hayden, Michael R; Lipton, Stuart A | Nat Med (2009 Dec) | 15 / 1407-13 |
PubMed Citation
|
30 |
Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alph ... | Koob, Andrew O; Ubhi, Kiren; Paulsson, Johan F; Kelly, Jeffery; Rockenstein, Edward; Mante, Michael; Adame, Anthony; Masliah, Eliezer | Exp Neurol (2010 Feb) | 221 / 267-74 |
PubMed Citation
|
31 |
Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: possible pharmacological ... | Nakamura, Tomohiro; Lipton, Stuart A | Cell Calcium (2010 Feb) | 47 / 190-7 |
PubMed Citation
|
32 |
Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfuncti ... | Gu, Zezong; Nakamura, Tomohiro; Lipton, Stuart A | Mol Neurobiol (2010 Jun) | 41 / 55-72 |
PubMed Citation
|
33 |
S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneratio ... | Nakamura, Tomohiro; Cieplak, Piotr; Cho, Dong-Hyung; Godzik, Adam; Lipton, Stuart A | Mitochondrion (2010 Aug) | 10 / 573-8 |
PubMed Citation
|
34 |
Direct reprogramming of mouse fibroblasts to neural progenitors. | Kim, Janghwan; Efe, Jem A; Zhu, Saiyong; Talantova, Maria; Yuan, Xu; Wang, Shufen; Lipton, Stuart A; Zhang, Kang; Ding, Sheng | Proc Natl Acad Sci U S A (2011 May 10) | 108 / 7838-43 |
PubMed Citation
|
35 |
Critical role of PINK1 in regulating Parkin protein levels in vivo. | Choo, Yeun Su; Tang, Chengyuan; Zhang, Zhuohua | Arch Neurol (2011 May) | 68 / 684-5 |
PubMed Citation
|
36 |
Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and n ... | Nakamura, T; Lipton, S A | Cell Death Differ (2011 Sep) | 18 / 1478-86 |
PubMed Citation
|
37 |
On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homo ... | Numajiri, Naoki; Takasawa, Kumi; Nishiya, Tadashi; Tanaka, Hirotaka; Ohno, Kazuki; Hayakawa, Wataru; Asada, Mariko; Matsuda, Hiromi; Azumi, Kaoru; Kamata, Hideaki; Nakamura, Tomohiro; Hara, Hideaki; Minami, Masabumi; Lipton, Stuart A; Uehara, Takashi | Proc Natl Acad Sci U S A (2011 Jun 21) | 108 / 10349-54 |
PubMed Citation
|
38 |
Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein ... | Tan, Jieqiong; Zhang, Tongmei; Jiang, Li; Chi, Jingwei; Hu, Dongshen; Pan, Qian; Wang, Danling; Zhang, Zhuohua | J Biol Chem (2011 Aug 26) | 286 / 29654-62 |
PubMed Citation
|
39 |
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. | Ambasudhan, Rajesh; Talantova, Maria; Coleman, Ronald; Yuan, Xu; Zhu, Saiyong; Lipton, Stuart A; Ding, Sheng | Cell Stem Cell (2011 Aug 5) | 9 / 113-8 |
PubMed Citation
|
40 |
S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptid ... | Qu, Jing; Nakamura, Tomohiro; Cao, Gang; Holland, Emily A; McKercher, Scott R; Lipton, Stuart A | Proc Natl Acad Sci U S A (2011 Aug 23) | 108 / 14330-5 |
PubMed Citation
|
41 |
Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock protein ... | Satoh, Takumi; Rezaie, Tayebeh; Seki, Masaaki; Sunico, Carmen R; Tabuchi, Takahito; Kitagawa, Tomomi; Yanagitai, Mika; Senzaki, Mutsumi; Kosegawa, Chihiro; Taira, Hideharu; McKercher, Scott R; Hoffman, Jennifer K; Roth, Gregory P; Lipton, Stuart A | J Neurochem (2011 Nov) | 119 / 569-78 |
PubMed Citation
|
42 |
Embargoed Publication: Title Restricted | Premkumar, Lakshmanane; Dobaczewska, Malgorzata K; Riedl, Stefan J | J Struct Biol (2011 Dec) | 176 / 414-8 |
PubMed Citation
|
43 |
MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian r ... | Cho, Eun-Gyung; Zaremba, Jeffrey D; McKercher, Scott R; Talantova, Maria; Tu, Shichun; Masliah, Eliezer; Chan, Shing Fai; Nakanishi, Nobuki; Terskikh, Alexey; Lipton, Stuart A | PLoS One (2011) | 6 / e24027 |
PubMed Citation
|
44 |
Aýý neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-asparta ... | You, Haitao; Tsutsui, Shigeki; Hameed, Shahid; Kannanayakal, Thomas J; Chen, Lina; Xia, Peng; Engbers, Jordan D T; Lipton, Stuart A; Stys, Peter K; Zamponi, Gerald W | Proc Natl Acad Sci U S A (2012 Jan 31) | 109 / 1737-42 |
PubMed Citation
|
45 |
Regulation of parkin and PINK1 by neddylation. | Choo, Yeun Su; Vogler, Georg; Wang, Danling; Kalvakuri, Sreehari; Iliuk, Anton; Tao, W Andy; Bodmer, Rolf; Zhang, Zhuohua | Hum Mol Genet (2012 Jun 1) | 21 / 2514-23 |
PubMed Citation
|
46 |
Isobaric tagging-based quantification by mass spectrometry of differentially regulated proteins in s ... | Banerjee, Sugato; Liao, Lujian; Russo, Rossella; Nakamura, Tomohiro; McKercher, Scott R; Okamoto, Shu-ichi; Haun, Florian; Nikzad, Rana; Zaidi, Rameez; Holland, Emily; Eroshkin, Alexey; Yates 3rd, John R; Lipton, Stuart A | Exp Neurol (2012 Aug) | 236 / 298-306 |
PubMed Citation
|
47 |
Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death i ... | Nakamura, Tomohiro; Cho, Dong-Hyung; Lipton, Stuart A | Exp Neurol (2012 Nov) | 238 / 12-21 |
PubMed Citation
|
48 |
S-nitrosylation of Cdk5: potential implications in amyloid-ýý-related neurotoxicity in Alzheimer dis ... | Qu, Jing; Nakamura, Tomohiro; Holland, Emily A; McKercher, Scott R; Lipton, Stuart A | Prion (2012 Sep-Oct) | 6 / 364-70 |
PubMed Citation
|
