Project Title: | GENOTOXICITY AND REPAIR OF TOBACCO-SPECIFIC NITROSAMINE DNA ADDUCTS |
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PI: | Spratt, Thomas E |
Institution: | Pennsylvania State Univ Hershey Med Ctr |
Grant Number: | R01ES021762 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA ... | Prakasha Gowda, A S; Spratt, Thomas E | R01ES021762 | Chem Res Toxicol (2017 Nov 20) | 29053918 | 2017 |
Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells. | Gowda, A S Prakasha; Suo, Zucai; Spratt, Thomas E | R01ES021762 | Chem Res Toxicol (2017 Feb 20) | 28067485 | 2017 |
Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase ... | Gowda, A S Prakasha; Krzeminski, Jacek; Amin, Shantu; Suo, Zucai; Spratt, Thomas E | R01ES021762 | Chem Res Toxicol (2017 May 15) | 28402640 | 2017 |
N2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Pol ... | Gowda, A S Prakasha; Lee, Marietta; Spratt, Thomas E | R01ES021762 | Angew Chem Int Ed Engl (2017 Mar 01) | 28140505 | 2017 |
Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases. | Basu, Ashis K; Pande, Paritosh; Bose, Arindam | R01ES021762, R01ES023350 | Chem Res Toxicol (2017 Jan 17) | 27760288 | 2017 |
DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl- ... | Gowda, A S Prakasha; Spratt, Thomas E | R01ES021762 | Chem Res Toxicol (2016 Nov 21) | 27741574 | 2016 |
DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Forme ... | Gowda, A S Prakasha; Spratt, Thomas E | R01ES021762 | Chem Res Toxicol (2016 Mar 21) | 26868090 | 2016 |
Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenz ... | Patra, Amritraj; Politica, Dustin A; Chatterjee, Arindom; Tokarsky, E John; Suo, Zucai; Basu, ... | R01ES021762 | Chembiochem (2016 Nov 03) | 27556902 | 2016 |
Base-Displaced Intercalated Structure of the N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduc ... | Politica, Dustin A; Malik, Chanchal K; Basu, Ashis K; Stone, Michael P | R01ES021762 | Chem Res Toxicol (2015 Dec 21) | 26641105 | 2015 |
Biological relevance of oxidative debris present in as-prepared graphene oxide. | Pattammattel, Ajith; Williams, Christina L; Pande, Paritosh; Tsui, William G; Basu, Ashis K; Ku ... | R01ES021762 | RSC Adv (2015 Jan 01) | 26257893 | 2015 |
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguan ... | Bose, Arindam; Pande, Paritosh; Jasti, Vijay P; Millsap, Amy D; Hawkins, Edward K; Rizzo, Carm ... | R01ES021762 | Nucleic Acids Res (2015 Sep 30) | 26220181 | 2015 |
Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency. | Gowda, A S Prakasha; Moldovan, George-Lucian; Spratt, Thomas E | R01ES021762 | J Biol Chem (2015 Jun 26) | 25963146 | 2015 |
Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitros ... | Weerasooriya, Savithri; Jasti, Vijay P; Bose, Arindam; Spratt, Thomas E; Basu, Ashis K | R01ES021762 | DNA Repair (Amst) (2015 Nov) | 26460881 | 2015 |
Unlike catalyzing error-free bypass of 8-oxodGuo, DNA polymerase λ is responsible for a significant ... | Pande, Paritosh; Haraguchi, Kazuhiro; Jiang, Yu-Lin; Greenberg, Marc M; Basu, Ashis K | R01ES021762 | Biochemistry (2015 Mar 17) | 25741586 | 2015 |
Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replicat ... | Pednekar, Varsha; Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K | R01ES021762 | Chem Res Toxicol (2014 Feb 17) | 24392701 | 2014 |
Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in ... | Pande, Paritosh; Malik, Chanchal K; Bose, Arindam; Jasti, Vijay P; Basu, Ashis K | R01ES021762 | Biochemistry (2014 Aug 19) | 25080294 | 2014 |
Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences. | Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K | R01ES021762, R01ES023350 | PLoS One (2014) | 25226389 | 2014 |