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Who We Fund: Publication Detail

Project Title: GENOTOXICITY AND REPAIR OF TOBACCO-SPECIFIC NITROSAMINE DNA ADDUCTS
PI: Spratt, Thomas E
Institution: Pennsylvania State Univ Hershey Med Ctr
Grant Number: R01ES021762

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Viewing 17 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA ...   Prakasha Gowda, A S; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2017 Nov 20) 29053918 Exiting the NIEHS site 2017 
Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells.   Gowda, A S Prakasha; Suo, Zucai; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2017 Feb 20) 28067485 Exiting the NIEHS site 2017 
Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase ...   Gowda, A S Prakasha; Krzeminski, Jacek; Amin, Shantu; Suo, Zucai; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2017 May 15) 28402640 Exiting the NIEHS site 2017 
N2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Pol ...   Gowda, A S Prakasha; Lee, Marietta; Spratt, Thomas E R01ES021762 Angew Chem Int Ed Engl (2017 Mar 01) 28140505 Exiting the NIEHS site 2017 
Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.   Basu, Ashis K; Pande, Paritosh; Bose, Arindam R01ES021762, R01ES023350 Chem Res Toxicol (2017 Jan 17) 27760288 Exiting the NIEHS site 2017 
DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl- ...   Gowda, A S Prakasha; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2016 Nov 21) 27741574 Exiting the NIEHS site 2016 
DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Forme ...   Gowda, A S Prakasha; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2016 Mar 21) 26868090 Exiting the NIEHS site 2016 
Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenz ...   Patra, Amritraj; Politica, Dustin A; Chatterjee, Arindom; Tokarsky, E John; Suo, Zucai; Basu, ... R01ES021762 Chembiochem (2016 Nov 03) 27556902 Exiting the NIEHS site 2016 
Base-Displaced Intercalated Structure of the N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduc ...   Politica, Dustin A; Malik, Chanchal K; Basu, Ashis K; Stone, Michael P R01ES021762 Chem Res Toxicol (2015 Dec 21) 26641105 Exiting the NIEHS site 2015 
Biological relevance of oxidative debris present in as-prepared graphene oxide.   Pattammattel, Ajith; Williams, Christina L; Pande, Paritosh; Tsui, William G; Basu, Ashis K; Ku ... R01ES021762 RSC Adv (2015 Jan 01) 26257893 Exiting the NIEHS site 2015 
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguan ...   Bose, Arindam; Pande, Paritosh; Jasti, Vijay P; Millsap, Amy D; Hawkins, Edward K; Rizzo, Carm ... R01ES021762 Nucleic Acids Res (2015 Sep 30) 26220181 Exiting the NIEHS site 2015 
Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency.   Gowda, A S Prakasha; Moldovan, George-Lucian; Spratt, Thomas E R01ES021762 J Biol Chem (2015 Jun 26) 25963146 Exiting the NIEHS site 2015 
Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitros ...   Weerasooriya, Savithri; Jasti, Vijay P; Bose, Arindam; Spratt, Thomas E; Basu, Ashis K R01ES021762 DNA Repair (Amst) (2015 Nov) 26460881 Exiting the NIEHS site 2015 
Unlike catalyzing error-free bypass of 8-oxodGuo, DNA polymerase λ is responsible for a significant ...   Pande, Paritosh; Haraguchi, Kazuhiro; Jiang, Yu-Lin; Greenberg, Marc M; Basu, Ashis K R01ES021762 Biochemistry (2015 Mar 17) 25741586 Exiting the NIEHS site 2015 
Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replicat ...   Pednekar, Varsha; Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K R01ES021762 Chem Res Toxicol (2014 Feb 17) 24392701 Exiting the NIEHS site 2014 
Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in ...   Pande, Paritosh; Malik, Chanchal K; Bose, Arindam; Jasti, Vijay P; Basu, Ashis K R01ES021762 Biochemistry (2014 Aug 19) 25080294 Exiting the NIEHS site 2014 
Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences.   Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K R01ES021762, R01ES023350 PLoS One (2014) 25226389 Exiting the NIEHS site 2014 
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