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National Institute of Environmental Health Sciences

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Publication Detail

Title: Regulation of ARGONAUTE10 Expression Enables Temporal and Spatial Precision in Axillary Meristem Initiation in Arabidopsis.

Authors: Zhang, Cui; Fan, Lusheng; Le, Brandon H; Ye, Peiyi; Mo, Beixin; Chen, Xuemei

Published In Dev Cell, (2020 12 07)

Abstract: Axillary meristems (AMs) give rise to lateral shoots and are critical to plant architecture. Understanding how developmental cues and environmental signals impact AM development will enable the improvement of plant architecture in agriculture. Here, we show that ARGONAUTE10 (AGO10), which sequesters miR165/166, promotes AM development through the miR165/166 target gene REVOLUTA. We reveal that AGO10 expression is precisely controlled temporally and spatially by auxin, brassinosteroids, and light to result in AM initiation only in the axils of leaves at a certain age. AUXIN RESPONSE FACTOR 5 (ARF5) activates while BRASSINAZOLE-RESISTANT 1 (BZR1) and PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) repress AGO10 transcription directly. In axils of young leaves, BZR1 and PIF4 repress AGO10 expression to prevent AM initiation. In axils of older leaves, ARF5 upregulates AGO10 expression to promote AM initiation. Our results uncover the spatiotemporal control of AM development through the cooperation of hormones and light converging on a regulator of microRNA.

PubMed ID: 33232670 Exiting the NIEHS site

MeSH Terms: Arabidopsis Proteins/genetics*; Arabidopsis Proteins/metabolism; Arabidopsis/genetics*; Arabidopsis/growth & development; Argonaute Proteins/genetics*; Argonaute Proteins/metabolism; Brassinosteroids/metabolism; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant*; Indoleacetic Acids/metabolism; Light Signal Transduction; Meristem/genetics; Meristem/growth & development*; Mutation/genetics; Plant Leaves/metabolism; Time Factors; Transcription, Genetic

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