Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02945-0005-0000-7 |
Chemical Name: | Trichloroethylene |
CASRN: | 79-01-6 |
NTP Study Type: | Genetic Toxicology - Bacterial Mutagenicity |
NTP Study ID: | 574937 |
Vehicle Control: | Dimethyl Sulfoxide |
Study Result: | Negative |
Table Instructions and Notes:
You are currently viewing the results for this Salmonella study's detailed data.
Individual strain data is presented as mean ± standard error.
Abbreviations are noted at bottom of page.
Trial summary calls are shown in parentheses.
Standard NTP Protocol
You are currently viewing the results for this Salmonella study's detailed data.
Individual strain data is presented as mean ± standard error.
Abbreviations are noted at bottom of page.
Trial summary calls are shown in parentheses.
Standard NTP Protocol
Dose |
No Activation (Positive) |
No Activation (Negative) |
10% RLI (Positive) |
10% RLI (Negative) |
||||
---|---|---|---|---|---|---|---|---|
Protocol | Plate Test - Vapor from liquid | Preincubation | Plate Test - Vapor from liquid | Preincubation | ||||
ug/Plate | Mean | ±SEM | Mean | ±SEM | Mean | ±SEM | Mean | ±SEM |
0 |
84 | 1.9 | 106 | 2.3 | 90 | 2.3 | 117 | 10.4 |
0.32 |
93 | 1.8 | 114 | 9.6 | ||||
0.63 |
98 | 3.5 | 154 | 2.3 | ||||
2.5 |
162 | .9 | 169 | 8.2 | ||||
1.25 |
138 | 4.6 | 173 | 9.3 | ||||
33 |
102 | 6.7 | 112 | 7.8 | ||||
100 |
98 | 8.4 | 101 | 6.4 | ||||
333 |
92 | 11 | 112 | 3.2 | ||||
1000 |
92 | 1.2 | 100 | 6.9 | ||||
3333 |
84 | 6.1 | 92 s | 5.4 | ||||
10000 |
72 s | 2.1 | 101 s | 11.4 | ||||
Positive Control | 692 | 32.5 | 1005 | 14.5 | 693 | 38.1 |
Dose |
No Activation (Positive) |
No Activation (Negative) |
10% RLI (Positive) |
10% RLI (Negative) |
||||
---|---|---|---|---|---|---|---|---|
Protocol | Plate Test - Vapor from liquid | Preincubation | Plate Test - Vapor from liquid | Preincubation | ||||
ug/Plate | Mean | ±SEM | Mean | ±SEM | Mean | ±SEM | Mean | ±SEM |
0 |
7 | 1.5 | 8 | 2 | 8 | 1.5 | 11 | .9 |
0.32 |
16 | 1.7 | 12 | 3.8 | ||||
0.63 |
26 | .9 | 19 | 2.6 | ||||
2.5 |
98 | 8.5 | 79 | 4.7 | ||||
1.25 |
51 | 4.2 | 53 | 1.7 | ||||
33 |
11 | 1.2 | 10 | .3 | ||||
100 |
8 | 1.3 | 8 | 1.5 | ||||
333 |
11 | .9 | 12 | 2 | ||||
1000 |
12 | 1.2 | 10 | .3 | ||||
3333 |
10 | 1.7 | 8 | 1.5 | ||||
10000 |
11 s | 1.5 | 9 s | 2.4 | ||||
Positive Control | 37 | 2.4 | 51 | 3.8 | 105 | 2.4 |
Abbreviations:
RLI = induced male Sprague Dawley rat liver S9
HLI = induced male Syrian hamster liver S9
s = Slight Toxicity; p = Precipitate; x = Slight Toxicity and Precipitate; t = Toxic;
RLI = induced male Sprague Dawley rat liver S9
HLI = induced male Syrian hamster liver S9
s = Slight Toxicity; p = Precipitate; x = Slight Toxicity and Precipitate; t = Toxic;