This study deploys the livelihoods theory in political ecology together with integrated methods including remote sensing, participatory geographic information systems, interviews and focus group discussions to explore the intricate and dynamic linkages between perennial wildfires and household food insecurity among smallholder farmers in the northern savannah zone of Ghana. Our results suggest that wildfires are a major pathway to household food insecurity in two ways, as perceived by the farmers. First, in instances where wildfires destroy the major crops of smallholders, they are unable to find enough food for the lean season which results in transitory food insecurity. Secondly, in the long term, the environmental impacts of wildfires on the soil lead to lower yields and inadequate food to meet household nutritional needs. Farmers then deploy certain strategies such as early-harvesting and switching to early-maturing crops to avoid with the perennial fires and these strategies further reinforce other dimensions of food insecurity such as nutrition insecurity. Because livelihoods strategies such as crop farming, hunting, charcoal production and herding intersect in the northern savannah zone, we recommend policy options that will engage community members in finding common ways of using shared spaces sustainably. Government should also adopt policies that will encourage domestication of certain livelihood strategies such as cattle herding.