Climate Change and Human Health Literature Portal
- Publisher http://dx.doi.org/10.2188/jea.JE20080074
Background: Although the relation between day-to-day temperature change and coronary heart disease (CHD) mortality is well established, it is unknown whether temperature variation within 1 day, ie, diurnal temperature range (DTR), is an independent risk factor for acute CHD death. Methods: We used time-series and case-crossover approaches to assess the relation between DTR and daily CHD mortality between 2001 and 2004 in Shanghai, China. Specifically, we used exposures averaged over periods varying from I to 5 days to assess the effects of DTR on CHD mortality. We estimated the percent increase in the number of daily deaths related to CHD that were associated with DTR, after adjustment for daily meteorologic conditions (temperature and relative humidity) and levels of outdoor air pollutants. Results: Both time-series and case-crossover analyses showed that DTR was significantly associated with the number of daily deaths related to CHD. A 1 degrees C increase in 2-day lagged DTR corresponded to a 2.46% (95% CI, 1.76% to 3.16%) increase in CHD mortality on time-series analysis, a 3.21% (95% CI, 2.23% to 4.19%) increase on unidirectional case-crossover analysis, and a 2.13% (95% CI, 1.04% to 3.22%) increase on bidirectional case-crossover analysis. Conclusions: Our findings suggest that DTR is an independent risk factor for acute CHD death.
Resource Description
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Air Pollution, Meteorological Factor, Temperature
- Air Pollution, Meteorological Factor, Temperature: Ground-Level Ozone, Particulate Matter, Other Air Pollution, Specify
- Ground-Level Ozone, Particulate Matter, Other Air Pollution, Specify: NO2;SO2
- Air Pollution, Meteorological Factor, Temperature: Variability
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Urban
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Non-United States
- Non-United States: Asia
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Cardiovascular Impact, Developmental Impact
- Cardiovascular Impact, Developmental Impact: Other Cardiovascular Impact, Specify
- Other Cardiovascular Impact, Specify: congenital heart defect mortality
- Cardiovascular Impact, Developmental Impact: Birth Outcome
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Research Article