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Climate Change and Human Health Literature Portal Warmer weather as a risk factor for hospitalisations due to urinary tract infections


Climate Change and Human Health Literature Portal

Simmering JE, Cavanaugh JE, Polgreen LA, Polgreen PM
Epidemiology and Infection. 146 (3): 386-393

The incidence of urinary tract infections (UTIs) is seasonal, and this seasonality may be explained by changes in weather, specifically, temperature. Using data from the Nationwide Inpatient Sample, we identified the geographic location for 581 813 hospital admissions with the primary diagnosis of a UTI and 56 630 773 non-UTI hospitalisations in the United States. Next, we used data from the National Climatic Data Center to estimate the monthly average temperature for each location. Using a case-control design, we modelled the odds of a hospital admission having a primary diagnosis of UTI as a function of demographics, payer, location, patient severity, admission month, year and the average temperature for the admission month. We found, after controlling for patient factors and month of admission, the odds of a UTI diagnosis increased with higher temperatures in a dose-dependent manner. For example, relative to months with average temperatures of 5-7.5 degrees C, an admission in a month with an average temperature of 27.5-30 degrees C has 20% higher odds of a primary diagnosis of UTI. However, in months with extremely high average temperatures (above 30 degrees C), the odds of a UTI admissions decrease, perhaps due to changes in behaviour. Thus, at a population level, UTI-related hospitalisations are associated with warmer weather.

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Resource Description

    Meteorological Factor, Seasonality, Temperature
    • Meteorological Factor, Seasonality, Temperature: Heat
    United States
    Urologic Impact
    Research Article
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