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Study Information
Study Attribute Value
CEBS Accession Number: 002-01370-0005-0000-8
Chemical Name: 2-Nitroethanol
CASRN: 625-48-9
NTP Study Type: Genetic Toxicology - Bacterial Mutagenicity
NTP Study ID: G625489C
Vehicle Control: Dimethyl Sulfoxide
Study Result: Weakly Positive

Table Instructions and Notes:
You are currently viewing the results for this Salmonella study's detailed data.
Individual strain data is presented as mean ± standard error.
Abbreviations are noted at bottom of page.
Trial summary calls are shown in parentheses.
Standard NTP Protocol

Strain: TA100
Dose No Activation
(Equivocal)
No Activation
(Negative)
Protocol Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM
 0         
85 3.7 64 5.4
12.5       
90 2.5 74 1.9
50         
94 1.3 74 9.5
125         
99 8.7 71 8.4
500         
122 13.5 75 7.9
1000         
43 4.7 t
1500         
t t
Positive Control 727 3.8 839 15.2

Strain: eColi pKM101
Dose No Activation
(Weakly Positive)
No Activation
(Weakly Positive)
Protocol Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM
 0         
149 6.4 127 8
50         
153 15.6 128 3.9
125         
152 10.4 130 4.3
500         
154 15.1 161 3.5
1000         
214 9.6 187 17.6
1500         
251 9.1 227 9.8
3000         
t t
Positive Control 1136 16.9 1045 67

Abbreviations:
RLI = induced male Sprague Dawley rat liver S9
HLI = induced male Syrian hamster liver S9
s = Slight Toxicity; p = Precipitate; x = Slight Toxicity and Precipitate; t = Toxic;