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Study Information
Study Attribute Value
CEBS Accession Number: 002-01808-0001-0000-0
Chemical Name: C.I. Solvent black 5
CASRN: 11099-03-9
NTP Study Type: Genetic Toxicology - Bacterial Mutagenicity
NTP Study ID: 203446
Vehicle Control: Dimethyl Sulfoxide
Study Result: Positive

Table Instructions and Notes:
You are currently viewing the results for this Salmonella study's detailed data.
Individual strain data is presented as mean ± standard error.
Abbreviations are noted at bottom of page.
Trial summary calls are shown in parentheses.
Standard NTP Protocol

Strain: TA100
Dose No Activation
(Negative) 		5% RLI
(Negative) 		30% RLI
(Equivocal) 		30% RLI
(Negative) 		30% HLI
(Negative) 		10% RLI
(Negative)
Protocol Preincubation Preincubation Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 135 2.3 149 8.8 130 7.8 142 5.6 159 .6 160 .9 
1         
 161 8.1 154 11.7 137 13.3 
3         
 139 2 121 13.7 151 3.7 
10         
 163 1.9 147 8.4 165 9.7 145 2.7 
33         
 138 7.2 134 6.2 200 2 150 4.6 136 3.3 
100         
 125 p 1.5 136 p 6.4 196 p 17.6 153 p 12 133 p 5.8 127 p 1.2 
333         
 94 p 5.2 137 p 5.8 115 p 14.1 
666         
 45 x 2.7 
1000         
 117 p 9.2 112 p 17.7 
1666         
 126 p 8.6 
3333         
 122 p 7.4 
6666         
 93 p 46.5
Positive Control 620 21 516 14.1 392 33 787 42.9 529 8.4 374 16.5

Strain: TA98
Dose No Activation
(Negative) 		30% RLI
(Positive) 		30% RLI
(Positive) 		30% RLI
(Positive) 		30% HLI
(Negative)
Protocol Preincubation Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 17 3.2 29 2.3 26 3.1 29 .6 34 3.3 
1         
 25 6.1 21 1.2 
3         
 27 2.3 34 3.8 
10         
 16 2.7 40 20 47 3.2 
33         
 16 1 117 10.8 99 3.4 84 6.1 
100         
 16 p 1.5 77 p 38.9 56 p 28.5 119 p 6.9 27 p 2.7 
333         
 14 p 1.5 46 p 3.5 24 p 1.3 
666         
 13 p 1.5 
1000         
 23 p 2.2 15 p 2.5 
1666         
 18 p 4 
3333         
 20 p 2.5 
6666         
 15 p 1.5
Positive Control 645 32 115 7.3 159 17.1 161 14.8 251 .9

Abbreviations:
RLI = induced male Sprague Dawley rat liver S9
HLI = induced male Syrian hamster liver S9
s = Slight Toxicity; p = Precipitate; x = Slight Toxicity and Precipitate; t = Toxic;