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Study Information
Study Attribute Value
CEBS Accession Number: 002-02810-0005-0000-8
Chemical Name: Sodium azide
CASRN: 26628-22-8
NTP Study Type: Genetic Toxicology - Bacterial Mutagenicity
NTP Study ID: G10164
Vehicle Control: Dimethyl Sulfoxide
Study Result: Positive

Table Instructions and Notes:
You are currently viewing the results for this Salmonella study's detailed data.
Individual strain data is presented as mean ± standard error.
Abbreviations are noted at bottom of page.
Trial summary calls are shown in parentheses.
Standard NTP Protocol

Strain: TA100
Dose No Activation
(Positive) 		No Activation
(Positive) 		10% RLI
(Positive) 		10% RLI
(Positive)
Protocol Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 194 15.1 161 10.5 109 10.1 123 12 
 0.25      
 361 10.3 324 14.5 
 0.1       
 318 10.1 199 3.6 
 0.5       
 552 21.3 443 12.9 106 9.5 145 10.1 
1         
 823 19.4 656 25.4 111 7.2 134 11.7 
2.5       
 1362 23.2 1179 19.4 134 6.2 188 10.1 
5         
 223 21 437 14.2 
10         
 2014 67.5 2273 75.4 800 30.2 1136 13.4 
50         
 3142 13.8 3134 26.7
Positive Control 838 39.1 698 18 473 45 2156 108

Strain: TA98
Dose No Activation
(Negative) 		No Activation
(Negative) 		10% RLI
(Negative) 		10% RLI
(Negative)
Protocol Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 20 3.2 16 3.5 33 5 26 3.5 
2.5       
 24 2.7 25 4.1 26 3.8 25 .6 
10         
 25 3.5 27 3.2 27 5.5 29 7 
50         
 26 1.5 22 1 33 4.1 34 3.8 
200         
 49 7.7 27 6.1 28 3.2 37 6.4 
500         
 32 4 23 2 30 1.8 45 5.3 
1000         
 22 4.7 t t 29 1.2
Positive Control 497 131.4 423 25.5 121 13.2 1256 34.9

Strain: eColi pKM101
Dose No Activation
(Positive) 		No Activation
(Positive) 		10% RLI
(Positive) 		10% RLI
(Positive)
Protocol Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 143 9 124 4.8 149 30.2 173 15.8 
2.5       
 154 3.1 106 3.2 132 4.7 199 5.6 
10         
 196 19 132 5.8 143 1.5 192 8 
50         
 310 16.8 237 2.4 240 4 298 5.7 
200         
 496 10.5 412 21.3 446 18.9 518 30.9 
500         
 611 6.8 553 14.6 621 45.4 635 7.5 
1000         
 501 25 525 33.7 848 12.2 412 23.6
Positive Control 929 30.7 1235 13.4 417 40 1116 57.2

Abbreviations:
RLI = induced male Sprague Dawley rat liver S9
HLI = induced male Syrian hamster liver S9
s = Slight Toxicity; p = Precipitate; x = Slight Toxicity and Precipitate; t = Toxic;