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Study Information
Study Attribute Value
CEBS Accession Number: 002-03251-0021-0000-6
Chemical Name: Cell Phone Radiation: GSM
CASRN: CELLPRADGSM
NTP Study Type: Genetic Toxicology - Micronucleus
NTP Study ID: G08013
Strain and Species: B6C3F1 Mouse
Study Result: Male: Negative; Female: Negative

Blood

Start Date Sample Collection Time Sex Methodology Used Route Dosing Regimen
2012-09-20 1 hour Male Flow Cytometry Whole Body Exposure Whole Body Exposure x 94, 94 day
  Dose
(w/kg)		 Animal
Number		 Polychromatic Erythrocytes
Trend P: 0.7327661498514245		 Normochromatic Erythrocytes
Trend P: 0.560921624849393
No. Examined Total MN Cells Percent PCE MN Cells
per 1000		 No. Examined Total MN Cells Percent NCE MN Cells
per 1000
Vehicle Control Air 
 0         
 101 20000 44 1.5 2.2 1331273 1847 98.5 1.4 
 0         
 12 20000 51 1.4 2.6 1394993 2124 98.6 1.5 
 0         
 40 20000 51 1.6 2.6 1261016 2013 98.4 1.6 
 0         
 5 20000 58 1.3 2.9 1523465 2372 98.7 1.6 
 0         
 98 20000 51 1.4 2.6 1392152 2012 98.6 1.4
Average ± SEM   1.433 ± 0.044 2.550 ± 0.111   0.000 ± 0.000 1.502 ± 0.038
 
Test Chemical Cell Phone Radiation: GSM 
2.5       
 229 20000 56 1.4 2.8 1412182 2104 98.6 1.5 
2.5       
 233 19999 61 1.5 3.1 1345626 1800 98.5 1.3 
2.5       
 267 20618 48 1.3 2.3 1558079 2309 98.7 1.5 
2.5       
 268 20000 58 1.5 2.9 1347247 2070 98.5 1.5 
2.5       
 269 20000 62 1.3 3.1 1513232 2395 98.7 1.6
Average ± SEM   1.387 ± 0.036 2.836 ± 0.138   0.000 ± 0.000 1.486 ± 0.041
Pairwise P   0.384   0.695
 
Test Chemical Cell Phone Radiation: GSM 
5         
 456 20000 54 1.3 2.7 1462271 2111 98.7 1.4 
5         
 458 20000 52 1.4 2.6 1374610 2043 98.6 1.5 
5         
 460 20000 35 1.2 1.8 1613770 2427 98.8 1.5 
5         
 478 20000 56 1.4 2.8 1372892 1932 98.6 1.4 
5         
 486 20000 50 1.5 2.5 1357355 1894 98.5 1.4
Average ± SEM   1.379 ± 0.043 2.470 ± 0.187   0.000 ± 0.000 1.447 ± 0.021
Pairwise P   0.455   0.781
 
Test Chemical Cell Phone Radiation: GSM 
10         
 656 20000 53 1.6 2.7 1207786 1875 98.4 1.6 
10         
 703 20000 51 1.6 2.6 1229042 1789 98.4 1.5 
10         
 714 20000 52 1.3 2.6 1493395 2212 98.7 1.5 
10         
 731 20000 41 1.3 2.1 1549351 2235 98.7 1.4 
10         
 733 20000 56 1.4 2.8 1411621 2185 98.6 1.5
Average ± SEM   1.445 ± 0.072 2.530 ± 0.127   0.000 ± 0.000 1.496 ± 0.023
Pairwise P   0.484   0.674
 

Blood

Start Date Sample Collection Time Sex Methodology Used Route Dosing Regimen
2012-09-21 1 hour Female Flow Cytometry Whole Body Exposure Whole Body Exposure x 94, 94 day
  Dose
(w/kg)		 Animal
Number		 Polychromatic Erythrocytes
Trend P: 0.9367207473669552		 Normochromatic Erythrocytes
Trend P: 0.8906655313158905
No. Examined Total MN Cells Percent PCE MN Cells
per 1000		 No. Examined Total MN Cells Percent NCE MN Cells
per 1000
Vehicle Control Air 
 0         
 151 20462 58 1.0 2.8 2080829 2624 99.0 1.3 
 0         
 187 20000 47 1.2 2.4 1685676 1984 98.8 1.2 
 0         
 198 20000 69 1.4 3.5 1394923 1672 98.6 1.2 
 0         
 199 20000 38 1.4 1.9 1419224 1649 98.6 1.2 
 0         
 202 20000 61 1.6 3.1 1227373 1372 98.4 1.1
Average ± SEM   1.311 ± 0.108 2.717 ± 0.271   0.000 ± 0.000 1.183 ± 0.024
 
Test Chemical Cell Phone Radiation: GSM 
2.5       
 327 20000 35 1.0 1.8 1982529 2084 99.0 1.1 
2.5       
 348 20000 81 1.1 4.1 1811291 2424 98.9 1.3 
2.5       
 384 20000 44 1.1 2.2 1847489 2046 98.9 1.1 
2.5       
 407 20000 48 1.3 2.4 1543872 1739 98.7 1.1 
2.5       
 416 20000 42 1.4 2.1 1359988 1486 98.6 1.1
Average ± SEM   1.178 ± 0.082 2.500 ± 0.402   0.000 ± 0.000 1.143 ± 0.050
Pairwise P   0.774   0.827
 
Test Chemical Cell Phone Radiation: GSM 
5         
 528 20000 53 1.0 2.7 2008298 2280 99.0 1.1 
5         
 573 20000 48 1.1 2.4 1829798 1890 98.9 1.0 
5         
 583 20000 51 1.3 2.6 1560517 1710 98.7 1.1 
5         
 597 20000 47 1.3 2.4 1545773 1636 98.7 1.1 
5         
 598 20000 36 1.2 1.8 1692693 1931 98.8 1.1
Average ± SEM   1.156 ± 0.055 2.350 ± 0.147   0.000 ± 0.000 1.093 ± 0.021
Pairwise P   0.850   0.893
 
Test Chemical Cell Phone Radiation: GSM 
10         
 736 20000 41 1.5 2.1 1346923 1514 98.5 1.1 
10         
 746 20000 49 1.5 2.5 1274734 1387 98.5 1.1 
10         
 782 20000 44 1.6 2.2 1247300 1581 98.4 1.3 
10         
 794 20000 33 1.4 1.7 1364525 1477 98.6 1.1 
10         
 836 20000 49 1.1 2.5 1775812 1849 98.9 1.0
Average ± SEM   1.429 ± 0.083 2.160 ± 0.149   0.000 ± 0.000 1.121 ± 0.039
Pairwise P   0.878   0.916