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Study Information
Study Attribute Value
CEBS Accession Number: 002-03251-0022-0000-7
Chemical Name: Cell Phone Radiation: GSM
CASRN: CELLPRADGSM
NTP Study Type: Genetic Toxicology - Micronucleus
NTP Study ID: G08013B
Strain and Species: Harlan Sprague Dawley Rat
Study Result: Male: Negative; Female: Negative

Blood

Start Date Sample Collection Time Sex Methodology Used Route Dosing Regimen
2012-12-20 1 hour Male Flow Cytometry Whole Body Exposure Whole Body Exposure x 94, 94 day
  Dose
(w/kg)		 Animal
Number		 Polychromatic Erythrocytes
Trend P: 0.9853836145969832		 Normochromatic Erythrocytes
Trend P: 0.9108250564306494
No. Examined Total MN Cells Percent PCE MN Cells
per 1000		 No. Examined Total MN Cells Percent NCE MN Cells
per 1000
Vehicle Control Air 
 0         
 507 20000 16 1.0 0.8 1971224 466 99.0 0.2 
 0         
 526 20000 23 1.0 1.2 2011588 1378 99.0 0.7 
 0         
 556 20000 19 0.9 1.0 2206832 373 99.1 0.2 
 0         
 590 20000 14 0.8 0.7 2570711 1232 99.2 0.5 
 0         
 603 20000 12 1.1 0.6 1849505 181 98.9 0.1
Average ± SEM   0.946 ± 0.051 0.840 ± 0.097   0.000 ± 0.000 0.334 ± 0.109
 
Test Chemical Cell Phone Radiation: GSM 
1.5       
 711 20000 9 1.1 0.5 1846736 505 98.9 0.3 
1.5       
 741 20000 8 1.1 0.4 1831386 202 98.9 0.1 
1.5       
 745 20000 18 1.0 0.9 1982489 326 99.0 0.2 
1.5       
 746 20000 17 0.9 0.9 2136221 218 99.1 0.1 
1.5       
 794 20000 9 1.1 0.5 1827680 116 98.9 0.1
Average ± SEM   1.032 ± 0.030 0.610 ± 0.109   0.000 ± 0.000 0.143 ± 0.036
Pairwise P   0.920   1.000
 
Test Chemical Cell Phone Radiation: GSM 
3         
 1025 20000 13 1.1 0.7 1884453 113 98.9 0.1 
3         
 922 20000 6 1.0 0.3 1935701 117 99.0 0.1 
3         
 952 20000 10 1.1 0.5 1788080 213 98.9 0.1 
3         
 958 20000 12 0.8 0.6 2621710 119 99.2 0.0 
3         
 967 20000 19 1.1 1.0 1863071 208 98.9 0.1
Average ± SEM   1.000 ± 0.062 0.600 ± 0.106   0.000 ± 0.000 0.079 ± 0.015
Pairwise P   0.961   1.000
 
Test Chemical Cell Phone Radiation: GSM 
6         
 1185 20000 8 1.1 0.4 1865990 355 98.9 0.2 
6         
 1204 20000 8 1.3 0.4 1527258 104 98.7 0.1 
6         
 1216 20000 14 1.0 0.7 2012506 230 99.0 0.1 
6         
 1232 20000 6 1.1 0.3 1784338 215 98.9 0.1 
6         
 1233 20000 13 1.0 0.7 2048732 322 99.0 0.2
Average ± SEM   1.082 ± 0.058 0.490 ± 0.078   0.000 ± 0.000 0.130 ± 0.021
Pairwise P   0.972   1.000
 

Blood

Start Date Sample Collection Time Sex Methodology Used Route Dosing Regimen
2012-12-20 1 hour Female Flow Cytometry Whole Body Exposure Whole Body Exposure x 94, 94 day
  Dose
(w/kg)		 Animal
Number		 Polychromatic Erythrocytes
Trend P: 0.5656051266288146		 Normochromatic Erythrocytes
Trend P: 0.7373049830651437
No. Examined Total MN Cells Percent PCE MN Cells
per 1000		 No. Examined Total MN Cells Percent NCE MN Cells
per 1000
Vehicle Control Air 
 0         
 617 20000 15 0.5 0.8 3898448 1190 99.5 0.3 
 0         
 638 20000 13 0.7 0.7 2877599 249 99.3 0.1 
 0         
 640 20000 9 0.7 0.5 2702727 240 99.3 0.1 
 0         
 662 20000 16 0.5 0.8 4292188 437 99.5 0.1 
 0         
 702 20000 9 0.9 0.5 2213602 165 99.1 0.1
Average ± SEM   0.659 ± 0.078 0.620 ± 0.073   0.000 ± 0.000 0.131 ± 0.044
 
Test Chemical Cell Phone Radiation: GSM 
1.5       
 850 20000 6 0.9 0.3 2157807 455 99.1 0.2 
1.5       
 867 20000 17 0.9 0.9 2305102 794 99.1 0.3 
1.5       
 886 20000 13 0.5 0.7 3922604 457 99.5 0.1 
1.5       
 903 20000 16 0.7 0.8 2809231 440 99.3 0.2 
1.5       
 906 20000 9 0.8 0.5 2397131 441 99.2 0.2
Average ± SEM   0.764 ± 0.073 0.610 ± 0.104   0.000 ± 0.000 0.202 ± 0.039
Pairwise P   0.519   0.377
 
Test Chemical Cell Phone Radiation: GSM 
3         
 1047 20000 18 0.8 0.9 2487713 332 99.2 0.1 
3         
 1049 20000 18 0.8 0.9 2621788 363 99.2 0.1 
3         
 1060 20000 12 0.6 0.6 3261376 424 99.4 0.1 
3         
 1072 20000 10 1.0 0.5 1913281 113 99.0 0.1 
3         
 1082 20000 12 0.5 0.6 4075005 367 99.5 0.1
Average ± SEM   0.737 ± 0.092 0.700 ± 0.084   0.000 ± 0.000 0.110 ± 0.015
Pairwise P   0.495   0.447
 
Test Chemical Cell Phone Radiation: GSM 
6         
 1236 20000 11 1.1 0.6 1787369 194 98.9 0.1 
6         
 1239 20000 13 0.9 0.7 2116086 466 99.1 0.2 
6         
 1285 20000 16 0.9 0.8 2098685 337 99.1 0.2 
6         
 1313 20000 11 1.0 0.6 1934785 174 99.0 0.1 
6         
 1314 20000 8 0.9 0.4 2086174 121 99.1 0.1
Average ± SEM   0.992 ± 0.033 0.590 ± 0.066   0.000 ± 0.000 0.127 ± 0.029
Pairwise P   0.525   0.476