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Study Information
Study Attribute Value
CEBS Accession Number: 002-01900-0005-0000-7
Chemical Name: Coconut oil acid diethanolamine condensate
CASRN: 68603-42-9
NTP Study Type: Genetic Toxicology - Micronucleus
NTP Study ID: A44271
Strain and Species: B6C3F1 Mouse
Study Result: Male: Positive; Female: Positive

Blood

Start Date Sample Collection Time Sex Cell Methodology Used Dosing Regimen Route Trend Test P-Value
1992-02-12 0 hour Female NCE Slide Scoring Dermal x 66, 92 day Dermal 0.001
  Dose (mg/kg) Number of Animals Scored Mean MN-NCE/1000 NCE ± SEM Pairwise P
Vehicle Control Ethanol 
 0         
 5 1.400 ± 0.100
Test Chemical Coconut oil acid diethanolamine condensate 
50         
 5 1.700 ± 0.250 0.295 
100         
 5 2.200 ± 0.250 0.091 
200         
 5 2.300 ± 0.410 0.069 
400         
 5 2.100 ± 0.370 0.118 
800         
 5 3.400 ± 0.190 0.002

Blood

Start Date Sample Collection Time Sex Cell Methodology Used Dosing Regimen Route Trend Test P-Value
1992-02-12 0 hour Male NCE Slide Scoring Dermal x 66, 92 day Dermal 0.015
  Dose (mg/kg) Number of Animals Scored Mean MN-NCE/1000 NCE ± SEM Pairwise P
Vehicle Control Ethanol 
 0         
 5 1.600 ± 0.400
Test Chemical Coconut oil acid diethanolamine condensate 
50         
 5 2.300 ± 0.250 0.131 
100         
 5 2.900 ± 0.430 0.026 
200         
 5 3.000 ± 0.610 0.019 
400         
 5 2.700 ± 0.200 0.047 
800         
 5 3.500 ± 0.420 0.004