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Your Environment. Your Health.

Project 1: Arsenic and Maternal and Infant Immune Function

Parent Title:
Children's Environmental Health & Disease Prevention Research Center at Dartmouth
Grant Number:
Principal Investigator:
Karagas, Margaret Rita (Contact); Nadeau, Kari C (subcontract, Stanford University)
Dartmouth College
Most Recent Award Year:
Lifestage of Participants:
Exposure: Prenatal; Infant (0-1 year); Adulthood (mother)
Assessment: Infant (0-1 year); Adulthood (mother)
Metals: Arsenic; Cadmium; Lead; Manganese; Mercury/methylmercury; Zinc
Nutrition/Diet/Supplements: Folate; Selenium
Health Outcomes:
Immune Outcomes: Immune function; Infection
Biological Sample:
Blood; Urine (mother)
Other Participant Data:
Vaccine response (antibody titers to tetanus and diphtheria)
Genes or Other DNA Products Studied:
Genes involved in arsenic metabolism

Related NIEHS-Funded Study Populations

The New Hampshire Birth Cohort Study

Principal Investigator:
Dartmouth College
New Hampshire; Vermont
Number of Participants::
2,000+ Mother-infant pairs
Brief Description::
This is a prospective pregnancy cohort study of mothers who use private wells for household water in New Hampshire designed to evaluate maternal/child health impacts of arsenic and other contaminants. The study has recruited over 2,500 mother-infant pairs (over 4,000 individuals) since 2009.
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